The QDREC web server: Determining dose-response characteristics of complex macroparasites in phenotypic drug screens

Bioinformatics

Volumn 31, Issue 9, 2015, Pages 1515-1518

  Asarnow, Daniel ^a   Rojo Arreola, Liliana ^b   Suzuki, Brian M ^b,c   Caffrey, Conor R ^b,c   Singh, Rahul ^a,c  

^a SAN FRANCISCO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of California at San Francisco   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VERMES;

ANTHELMINTIC AGENT; ANTISCHISTOSOMAL AGENT;

ANIMAL; COMPUTER PROGRAM; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; DRUG SENSITIVITY; GROWTH, DEVELOPMENT AND AGING; INTERNET; PHENOTYPE; PROCEDURES; SCHISTOSOMA; VALIDATION STUDY;

ANIMALS; ANTHELMINTICS; DOSE-RESPONSE RELATIONSHIP, DRUG; INTERNET; PARASITIC SENSITIVITY TESTS; PHENOTYPE; SCHISTOSOMA; SCHISTOSOMICIDES; SOFTWARE;

EID: 84928400310     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btu831     Document Type: Article

References (7)

1. Asarnow, D.E. and Singh, R. (2013) Segmenting the etiological agent of schistosomiasis for high-content screening. IEEE Trans. Med. Imaging, 32, 1007-1018.
2. Lee, H. et al. (2012) Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis. BMC Genomics, 13, S4.
3. Marcellino, C. et al. (2012) WormAssay: A novel computer application for whole-plate motion-based screening of macroscopic parasites. PLoS Negl. Trop. Dis., 6, e1494.
4. Paveley, R.A. et al. (2012) Whole organism high-content screening by labelfree, image-based Bayesian classification for parasitic diseases. PLoS Negl. Trop. Dis., 6, e1762.
5. Saha, U. and Singh, R. (2012) Vision-based tracking of complex macroparasites for high-content phenotypic drug screening. In: Bebis, G. et al. (eds.), Advances in Visual Computing(Lecture Notes in Computer Science). Springer, Heidelberg, pp. 104-114.
6. Singh, R. et al. (2009) Automated image-based phenotypic screening for high-throughput drug discovery. In: Proc. 22nd IEEE International Symposium on Computer-Based Medical Systems, 2009. CBMS 2009. IEEE, pp. 1-8.
7. World Health Organization (2013) Sustaining the drive to overcome the global impact of neglected tropical diseases: second WHO report on neglected tropical diseases. World Health Organization, Geneva, Switzerland.