메뉴 건너뛰기




Volumn 17, Issue 5, 2015, Pages

Role for Combination Therapy in Diabetic Dyslipidemia

Author keywords

Dyslipidemia; Ezetimibe; Fibrates; Fish oil; Statins; Type 2 diabetes mellitus

Indexed keywords

ATORVASTATIN; COLESTIPOL; EZETIMIBE; FIBRIC ACID DERIVATIVE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ICOSAPENTAENOIC ACID; ICOSAPENTAENOIC ACID ETHYL ESTER; LAROPIPRANT; LAROPIPRANT PLUS NICOTINIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; NICOTINIC ACID; OMEGA 3 ACID ETHYL ESTER; PLACEBO; SIMVASTATIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTILIPEMIC AGENT;

EID: 84928347801     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-015-0589-5     Document Type: Review
Times cited : (24)

References (74)
  • 1
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27(5):1047–53.
    • (2004) Diabetes Care , vol.27 , Issue.5 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 2
    • 49649083150 scopus 로고    scopus 로고
    • Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study
    • Fox CS, Pencina MJ, Wilson PW, Paynter NP, Vasan RS, D’Agostino Sr RB. Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study. Diabetes Care. 2008;31(8):1582–4.
    • (2008) Diabetes Care , vol.31 , Issue.8 , pp. 1582-1584
    • Fox, C.S.1    Pencina, M.J.2    Wilson, P.W.3    Paynter, N.P.4    Vasan, R.S.5    D’Agostino, R.B.6
  • 3
    • 0018764335 scopus 로고
    • Diabetes and cardiovascular disease. The Framingham study
    • COI: 1:STN:280:DyaE1M7lsVCksg%3D%3D
    • Kannel WB, McGee DL. Diabetes and cardiovascular disease. The Framingham study. JAMA. 1979;241(19):2035–8.
    • (1979) JAMA , vol.241 , Issue.19 , pp. 2035-2038
    • Kannel, W.B.1    McGee, D.L.2
  • 4
    • 34247483998 scopus 로고    scopus 로고
    • Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study
    • Fox CS, Coady S, Sorlie PD, D’Agostino Sr RB, Pencina MJ, Vasan RS, et al. Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study. Circulation. 2007;115(12):1544–50.
    • (2007) Circulation , vol.115 , Issue.12 , pp. 1544-1550
    • Fox, C.S.1    Coady, S.2    Sorlie, P.D.3    D’Agostino, R.B.4    Pencina, M.J.5    Vasan, R.S.6
  • 5
    • 84907494626 scopus 로고    scopus 로고
    • Prevalence and incidence trends for diagnosed diabetes among adults aged 20 to 79 years, United States, 1980–2012
    • COI: 1:CAS:528:DC%2BC2cXhvVCjt7fE
    • Geiss LS, Wang J, Cheng YJ, Thompson TJ, Barker L, Li Y, et al. Prevalence and incidence trends for diagnosed diabetes among adults aged 20 to 79 years, United States, 1980–2012. JAMA. 2014;312(12):1218–26.
    • (2014) JAMA , vol.312 , Issue.12 , pp. 1218-1226
    • Geiss, L.S.1    Wang, J.2    Cheng, Y.J.3    Thompson, T.J.4    Barker, L.5    Li, Y.6
  • 6
    • 0037434064 scopus 로고    scopus 로고
    • Cardiovascular disease in type 2 diabetes mellitus: current management guidelines
    • Mooradian AD. Cardiovascular disease in type 2 diabetes mellitus: current management guidelines. Arch Intern Med. 2003;163(1):33–40.
    • (2003) Arch Intern Med , vol.163 , Issue.1 , pp. 33-40
    • Mooradian, A.D.1
  • 7
    • 0346962889 scopus 로고    scopus 로고
    • Treating to New Targets (TNT) Study: does lowering low-density lipoprotein cholesterol levels below currently recommended guidelines yield incremental clinical benefit?
    • Waters DD, Guyton JR, Herrington DM, McGowan MP, Wenger NK, Shear C, et al. Treating to New Targets (TNT) Study: does lowering low-density lipoprotein cholesterol levels below currently recommended guidelines yield incremental clinical benefit? Am J Cardiol. 2004;93(2):154–8.
    • (2004) Am J Cardiol , vol.93 , Issue.2 , pp. 154-158
    • Waters, D.D.1    Guyton, J.R.2    Herrington, D.M.3    McGowan, M.P.4    Wenger, N.K.5    Shear, C.6
  • 8
    • 33749049339 scopus 로고    scopus 로고
    • Lower is better: implications of the Treating to New Targets (TNT) study for Canadian patients
    • COI: 1:CAS:528:DC%2BD28XhtVWktrfO
    • Fitchett DH, Leiter LA, Goodman SG, Langer A. Lower is better: implications of the Treating to New Targets (TNT) study for Canadian patients. Can J Cardiol. 2006;22(10):835–9.
    • (2006) Can J Cardiol , vol.22 , Issue.10 , pp. 835-839
    • Fitchett, D.H.1    Leiter, L.A.2    Goodman, S.G.3    Langer, A.4
  • 9
    • 84880698302 scopus 로고    scopus 로고
    • Is type 2 diabetes really a coronary heart disease risk equivalent?
    • COI: 1:CAS:528:DC%2BC3sXhtVCgsbvK
    • Saely CH, Drexel H. Is type 2 diabetes really a coronary heart disease risk equivalent? Vasc Pharmacol. 2013;59(1–2):11–8.
    • (2013) Vasc Pharmacol , vol.59 , Issue.1-2 , pp. 11-18
    • Saely, C.H.1    Drexel, H.2
  • 10
    • 21544465313 scopus 로고    scopus 로고
    • Should diabetes be considered a coronary heart disease risk equivalent?: results from 25 years of follow-up in the Renfrew and Paisley survey
    • Whiteley L, Padmanabhan S, Hole D, Isles C. Should diabetes be considered a coronary heart disease risk equivalent?: results from 25 years of follow-up in the Renfrew and Paisley survey. Diabetes Care. 2005;28(7):1588–93.
    • (2005) Diabetes Care , vol.28 , Issue.7 , pp. 1588-1593
    • Whiteley, L.1    Padmanabhan, S.2    Hole, D.3    Isles, C.4
  • 11
    • 0023025526 scopus 로고
    • Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT)
    • COI: 1:STN:280:DyaL2s%2FjslWktg%3D%3D
    • Stamler J, Wentworth D, Neaton JD. Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT). JAMA. 1986;256(20):2823–8.
    • (1986) JAMA , vol.256 , Issue.20 , pp. 2823-2828
    • Stamler, J.1    Wentworth, D.2    Neaton, J.D.3
  • 12
    • 0030734710 scopus 로고    scopus 로고
    • Study 27. Plasma lipids and lipoproteins at diagnosis of NIDDM by age and sex
    • Prospective Diabetes UK. Study 27. Plasma lipids and lipoproteins at diagnosis of NIDDM by age and sex. Diabetes Care. 1997;20(11):1683–7.
    • (1997) Diabetes Care , vol.20 , Issue.11 , pp. 1683-1687
    • Prospective Diabetes, U.K.1
  • 13
    • 0022206133 scopus 로고
    • Lipids, diabetes, and coronary heart disease: insights from the Framingham Study
    • COI: 1:STN:280:DyaL28%2FkslGjtQ%3D%3D
    • Kannel WB. Lipids, diabetes, and coronary heart disease: insights from the Framingham Study. Am Heart J. 1985;110(5):1100–7.
    • (1985) Am Heart J , vol.110 , Issue.5 , pp. 1100-1107
    • Kannel, W.B.1
  • 14
    • 3142735789 scopus 로고    scopus 로고
    • The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up
    • Almdal T, Scharling H, Jensen JS, Vestergaard H. The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up. Arch Intern Med. 2004;164(13):1422–6.
    • (2004) Arch Intern Med , vol.164 , Issue.13 , pp. 1422-1426
    • Almdal, T.1    Scharling, H.2    Jensen, J.S.3    Vestergaard, H.4
  • 15
    • 60749131994 scopus 로고    scopus 로고
    • Dyslipidemia in type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BD1MXit1KrtLc%3D
    • Mooradian AD. Dyslipidemia in type 2 diabetes mellitus. Nat Clin Pract Endocrinol Metab. 2009;5(3):150–9.
    • (2009) Nat Clin Pract Endocrinol Metab , vol.5 , Issue.3 , pp. 150-159
    • Mooradian, A.D.1
  • 16
    • 0029922613 scopus 로고    scopus 로고
    • High prevalence of small LDL particles in non-insulin-dependent diabetic patients with nephropathy
    • COI: 1:CAS:528:DyaK28XjtlSmtb8%3D
    • Hirano T, Naito H, Kurokawa M, Ebara T, Nagano S, Adachi M, et al. High prevalence of small LDL particles in non-insulin-dependent diabetic patients with nephropathy. Atherosclerosis. 1996;123(1–2):57–72.
    • (1996) Atherosclerosis , vol.123 , Issue.1-2 , pp. 57-72
    • Hirano, T.1    Naito, H.2    Kurokawa, M.3    Ebara, T.4    Nagano, S.5    Adachi, M.6
  • 17
    • 85027944383 scopus 로고    scopus 로고
    • Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study
    • COI: 1:CAS:528:DC%2BC38XnsVKrsb4%3D
    • Parish S, Offer A, Clarke R, Hopewell JC, Hill MR, Otvos JD, et al. Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study. Circulation. 2012;125(20):2469–78.
    • (2012) Circulation , vol.125 , Issue.20 , pp. 2469-2478
    • Parish, S.1    Offer, A.2    Clarke, R.3    Hopewell, J.C.4    Hill, M.R.5    Otvos, J.D.6
  • 18
    • 0032913707 scopus 로고    scopus 로고
    • Dyslipidemia of central obesity and insulin resistance
    • Brunzell JD, Hokanson JE. Dyslipidemia of central obesity and insulin resistance. Diabetes Care. 1999;22 Suppl 3:C10–3.
    • (1999) Diabetes Care , vol.22 , pp. 10-13
    • Brunzell, J.D.1    Hokanson, J.E.2
  • 19
    • 23244459229 scopus 로고    scopus 로고
    • Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia
    • COI: 1:CAS:528:DC%2BD2MXmtlOnur0%3D
    • Adiels M, Boren J, Caslake MJ, Stewart P, Soro A, Westerbacka J, et al. Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia. Arterioscler Thromb Vasc Biol. 2005;25(8):1697–703.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.8 , pp. 1697-1703
    • Adiels, M.1    Boren, J.2    Caslake, M.J.3    Stewart, P.4    Soro, A.5    Westerbacka, J.6
  • 20
    • 0028858162 scopus 로고
    • Acute hyperinsulinemia decreases the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in NIDDM
    • COI: 1:CAS:528:DyaK2MXotVGhurc%3D
    • Cummings MH, Watts GF, Umpleby AM, Hennessy TR, Kelly JM, Jackson NC, et al. Acute hyperinsulinemia decreases the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in NIDDM. Diabetes. 1995;44(9):1059–65.
    • (1995) Diabetes , vol.44 , Issue.9 , pp. 1059-1065
    • Cummings, M.H.1    Watts, G.F.2    Umpleby, A.M.3    Hennessy, T.R.4    Kelly, J.M.5    Jackson, N.C.6
  • 21
    • 0037898380 scopus 로고    scopus 로고
    • Diabetic dyslipidaemia: from basic research to clinical practice
    • Taskinen MR. Diabetic dyslipidaemia: from basic research to clinical practice. Diabetologia. 2003;46(6):733–49.
    • (2003) Diabetologia , vol.46 , Issue.6 , pp. 733-749
    • Taskinen, M.R.1
  • 22
    • 31344447948 scopus 로고    scopus 로고
    • The metabolic syndrome: inflammation, diabetes mellitus, and cardiovascular disease
    • COI: 1:CAS:528:DC%2BD28XnvVagug%3D%3D
    • Haffner SM. The metabolic syndrome: inflammation, diabetes mellitus, and cardiovascular disease. Am J Cardiol. 2006;97(2A):3–11.
    • (2006) Am J Cardiol , vol.97 , Issue.2A , pp. 3-11
    • Haffner, S.M.1
  • 23
    • 0032487560 scopus 로고    scopus 로고
    • Dyslipoproteinaemia and hyperoxidative stress in the pathogenesis of endothelial dysfunction in non-insulin dependent diabetes mellitus: an hypothesis
    • COI: 1:CAS:528:DyaK1cXntVyjt7Y%3D
    • Watts GF, Playford DA. Dyslipoproteinaemia and hyperoxidative stress in the pathogenesis of endothelial dysfunction in non-insulin dependent diabetes mellitus: an hypothesis. Atherosclerosis. 1998;141(1):17–30.
    • (1998) Atherosclerosis , vol.141 , Issue.1 , pp. 17-30
    • Watts, G.F.1    Playford, D.A.2
  • 24
    • 77955652957 scopus 로고    scopus 로고
    • Metabolic dyslipidemia and risk of future coronary heart disease in apparently healthy men and women: the EPIC-Norfolk prospective population study
    • Rana JS, Visser ME, Arsenault BJ, Despres JP, Stroes ES, Kastelein JJ, et al. Metabolic dyslipidemia and risk of future coronary heart disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Int J Cardiol. 2010;143(3):399–404.
    • (2010) Int J Cardiol , vol.143 , Issue.3 , pp. 399-404
    • Rana, J.S.1    Visser, M.E.2    Arsenault, B.J.3    Despres, J.P.4    Stroes, E.S.5    Kastelein, J.J.6
  • 25
    • 84901441620 scopus 로고    scopus 로고
    • Weight loss, glycemic control, and cardiovascular disease risk factors in response to differential diet composition in a weight loss program in type 2 diabetes: a randomized controlled trial
    • COI: 1:CAS:528:DC%2BC2cXhtFGrt7rI
    • Rock CL, Flatt SW, Pakiz B, Taylor KS, Leone AF, Brelje K, et al. Weight loss, glycemic control, and cardiovascular disease risk factors in response to differential diet composition in a weight loss program in type 2 diabetes: a randomized controlled trial. Diabetes Care. 2014;37(6):1573–80.
    • (2014) Diabetes Care , vol.37 , Issue.6 , pp. 1573-1580
    • Rock, C.L.1    Flatt, S.W.2    Pakiz, B.3    Taylor, K.S.4    Leone, A.F.5    Brelje, K.6
  • 26
    • 84892649479 scopus 로고    scopus 로고
    • Standards of medical care in diabetes—2014
    • American Diabetes A. Standards of medical care in diabetes—2014. Diabetes Care. 2014;37 Suppl 1:S14–80.
    • (2014) Diabetes Care , vol.37 , pp. 14-80
  • 27
    • 0036500807 scopus 로고    scopus 로고
    • Cholesterol treatment guidelines update
    • Safeer RS, Ugalat PS. Cholesterol treatment guidelines update. Am Fam Physician. 2002;65(5):871–80.
    • (2002) Am Fam Physician , vol.65 , Issue.5 , pp. 871-880
    • Safeer, R.S.1    Ugalat, P.S.2
  • 28
    • 84875787136 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with a Mediterranean diet
    • COI: 1:CAS:528:DC%2BC3sXls1akt7c%3D
    • Estruch R, Ros E, Salas-Salvado J, Covas MI, Corella D, Aros F, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013;368(14):1279–90.
    • (2013) N Engl J Med , vol.368 , Issue.14 , pp. 1279-1290
    • Estruch, R.1    Ros, E.2    Salas-Salvado, J.3    Covas, M.I.4    Corella, D.5    Aros, F.6
  • 29
    • 84891642790 scopus 로고    scopus 로고
    • Prevention of diabetes with Mediterranean diets: a subgroup analysis of a randomized trial
    • Salas-Salvado J, Bullo M, Estruch R, Ros E, Covas MI, Ibarrola-Jurado N, et al. Prevention of diabetes with Mediterranean diets: a subgroup analysis of a randomized trial. Ann Intern Med. 2014;160(1):1–10.
    • (2014) Ann Intern Med , vol.160 , Issue.1 , pp. 1-10
    • Salas-Salvado, J.1    Bullo, M.2    Estruch, R.3    Ros, E.4    Covas, M.I.5    Ibarrola-Jurado, N.6
  • 30
    • 84880323061 scopus 로고    scopus 로고
    • Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes
    • Look ARG, Wing RR, Bolin P, Brancati FL, Bray GA, Clark JM, et al. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med. 2013;369(2):145–54.
    • (2013) N Engl J Med , vol.369 , Issue.2 , pp. 145-154
    • Look, A.R.G.1    Wing, R.R.2    Bolin, P.3    Brancati, F.L.4    Bray, G.A.5    Clark, J.M.6
  • 31
    • 34548757192 scopus 로고    scopus 로고
    • Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial
    • Sigal RJ, Kenny GP, Boule NG, Wells GA, Prud’homme D, Fortier M, et al. Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial. Ann Intern Med. 2007;147(6):357–69.
    • (2007) Ann Intern Med , vol.147 , Issue.6 , pp. 357-369
    • Sigal, R.J.1    Kenny, G.P.2    Boule, N.G.3    Wells, G.A.4    Prud’homme, D.5    Fortier, M.6
  • 32
    • 0345374668 scopus 로고    scopus 로고
    • High-density lipoprotein-cholesterol, its subfractions, and responses to exercise training are dependent on endothelial lipase genotype
    • COI: 1:CAS:528:DC%2BD3sXosVyntbw%3D
    • Halverstadt A, Phares DA, Ferrell RE, Wilund KR, Goldberg AP, Hagberg JM. High-density lipoprotein-cholesterol, its subfractions, and responses to exercise training are dependent on endothelial lipase genotype. Metab Clin Exp. 2003;52(11):1505–11.
    • (2003) Metab Clin Exp , vol.52 , Issue.11 , pp. 1505-1511
    • Halverstadt, A.1    Phares, D.A.2    Ferrell, R.E.3    Wilund, K.R.4    Goldberg, A.P.5    Hagberg, J.M.6
  • 33
    • 30944434674 scopus 로고    scopus 로고
    • Apolipoprotein A1 genotype affects the change in high density lipoprotein cholesterol subfractions with exercise training
    • COI: 1:CAS:528:DC%2BD28Xos1ejug%3D%3D
    • Ruano G, Seip RL, Windemuth A, Zollner S, Tsongalis GJ, Ordovas J, et al. Apolipoprotein A1 genotype affects the change in high density lipoprotein cholesterol subfractions with exercise training. Atherosclerosis. 2006;185(1):65–9.
    • (2006) Atherosclerosis , vol.185 , Issue.1 , pp. 65-69
    • Ruano, G.1    Seip, R.L.2    Windemuth, A.3    Zollner, S.4    Tsongalis, G.J.5    Ordovas, J.6
  • 34
    • 0036281792 scopus 로고    scopus 로고
    • Changes in high-density lipoprotein-cholesterol subfractions with exercise training may be dependent on cholesteryl ester transfer protein (CETP) genotype
    • COI: 1:CAS:528:DC%2BD38XktlCru7w%3D
    • Wilund KR, Ferrell RE, Phares DA, Goldberg AP, Hagberg JM. Changes in high-density lipoprotein-cholesterol subfractions with exercise training may be dependent on cholesteryl ester transfer protein (CETP) genotype. Metab Clin Exp. 2002;51(6):774–8.
    • (2002) Metab Clin Exp , vol.51 , Issue.6 , pp. 774-778
    • Wilund, K.R.1    Ferrell, R.E.2    Phares, D.A.3    Goldberg, A.P.4    Hagberg, J.M.5
  • 35
    • 38049033935 scopus 로고    scopus 로고
    • Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis
    • Kearney PM, Blackwell L, Collins R, Keech A, Simes J, et al. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet. 2008;371(9607):117–25.
    • (2008) Lancet , vol.371 , Issue.9607 , pp. 117-125
    • Kearney, P.M.1    Blackwell, L.2    Collins, R.3    Keech, A.4    Simes, J.5
  • 36
    • 79959428660 scopus 로고    scopus 로고
    • Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis
    • COI: 1:CAS:528:DC%2BC3MXotVantLs%3D
    • Preiss D, Seshasai SR, Welsh P, Murphy SA, Ho JE, Waters DD, et al. Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis. JAMA. 2011;305(24):2556–64.
    • (2011) JAMA , vol.305 , Issue.24 , pp. 2556-2564
    • Preiss, D.1    Seshasai, S.R.2    Welsh, P.3    Murphy, S.A.4    Ho, J.E.5    Waters, D.D.6
  • 37
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials
    • Baigent C, Blackwell L, Emberson J, Holland LE, Reith C, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376(9753):1670–81.
    • (2010) Lancet , vol.376 , Issue.9753 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3    Holland, L.E.4    Reith, C.5
  • 40
    • 84864861863 scopus 로고    scopus 로고
    • Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial
    • COI: 1:CAS:528:DC%2BC38XhtF2hs7%2FI
    • Ridker PM, Pradhan A, MacFadyen JG, Libby P, Glynn RJ. Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial. Lancet. 2012;380(9841):565–71.
    • (2012) Lancet , vol.380 , Issue.9841 , pp. 565-571
    • Ridker, P.M.1    Pradhan, A.2    MacFadyen, J.G.3    Libby, P.4    Glynn, R.J.5
  • 41
    • 77549087054 scopus 로고    scopus 로고
    • Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials
    • COI: 1:CAS:528:DC%2BC3cXisFart74%3D
    • Sattar N, Preiss D, Murray HM, Welsh P, Buckley BM, de Craen AJ, et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet. 2010;375(9716):735–42.
    • (2010) Lancet , vol.375 , Issue.9716 , pp. 735-742
    • Sattar, N.1    Preiss, D.2    Murray, H.M.3    Welsh, P.4    Buckley, B.M.5    de Craen, A.J.6
  • 42
    • 56349154187 scopus 로고    scopus 로고
    • The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia
    • Fruchart JC, Sacks F, Hermans MP, Assmann G, Brown WV, Ceska R, et al. The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia. Am J Cardiol. 2008;102(10 Suppl):1–34.
    • (2008) Am J Cardiol , vol.102 , Issue.10 , pp. 1-34
    • Fruchart, J.C.1    Sacks, F.2    Hermans, M.P.3    Assmann, G.4    Brown, W.V.5    Ceska, R.6
  • 43
    • 0037472879 scopus 로고    scopus 로고
    • Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes
    • Gaede P, Vedel P, Larsen N, Jensen GV, Parving HH, Pedersen O. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med. 2003;348(5):383–93.
    • (2003) N Engl J Med , vol.348 , Issue.5 , pp. 383-393
    • Gaede, P.1    Vedel, P.2    Larsen, N.3    Jensen, G.V.4    Parving, H.H.5    Pedersen, O.6
  • 44
    • 38949210220 scopus 로고    scopus 로고
    • Effect of a multifactorial intervention on mortality in type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1cXhs1entLc%3D
    • Gaede P, Lund-Andersen H, Parving HH, Pedersen O. Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med. 2008;358(6):580–91.
    • (2008) N Engl J Med , vol.358 , Issue.6 , pp. 580-591
    • Gaede, P.1    Lund-Andersen, H.2    Parving, H.H.3    Pedersen, O.4
  • 45
    • 84891816690 scopus 로고    scopus 로고
    • Atherogenic dyslipidemia and combination pharmacotherapy in diabetes: recent clinical trials
    • Hamilton SJ, Watts GF. Atherogenic dyslipidemia and combination pharmacotherapy in diabetes: recent clinical trials. Rev Diabet Stud RDS. 2013;10(2–3):191–203.
    • (2013) Rev Diabet Stud RDS , vol.10 , Issue.2-3 , pp. 191-203
    • Hamilton, S.J.1    Watts, G.F.2
  • 46
    • 77952708442 scopus 로고    scopus 로고
    • Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis
    • COI: 1:CAS:528:DC%2BC3cXmsleksrc%3D
    • Jun M, Foote C, Lv J, Neal B, Patel A, Nicholls SJ, et al. Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis. Lancet. 2010;375(9729):1875–84.
    • (2010) Lancet , vol.375 , Issue.9729 , pp. 1875-1884
    • Jun, M.1    Foote, C.2    Lv, J.3    Neal, B.4    Patel, A.5    Nicholls, S.J.6
  • 47
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • COI: 1:STN:280:DyaK3M%2FhsFaksw%3D%3D
    • Brown G, Albers JJ, Fisher LD, Schaefer SM, Lin JT, Kaplan C, et al. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N Engl J Med. 1990;323(19):1289–98.
    • (1990) N Engl J Med , vol.323 , Issue.19 , pp. 1289-1298
    • Brown, G.1    Albers, J.J.2    Fisher, L.D.3    Schaefer, S.M.4    Lin, J.T.5    Kaplan, C.6
  • 48
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
    • COI: 1:CAS:528:DC%2BD3MXoslyhsLs%3D
    • Brown BG, Zhao XQ, Chait A, Fisher LD, Cheung MC, Morse JS, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med. 2001;345(22):1583–92.
    • (2001) N Engl J Med , vol.345 , Issue.22 , pp. 1583-1592
    • Brown, B.G.1    Zhao, X.Q.2    Chait, A.3    Fisher, L.D.4    Cheung, M.C.5    Morse, J.S.6
  • 49
    • 10044281651 scopus 로고    scopus 로고
    • Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins
    • COI: 1:CAS:528:DC%2BD2MXhtVGnt7s%3D
    • Taylor AJ, Sullenberger LE, Lee HJ, Lee JK, Grace KA. Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins. Circulation. 2004;110(23):3512–7.
    • (2004) Circulation , vol.110 , Issue.23 , pp. 3512-3517
    • Taylor, A.J.1    Sullenberger, L.E.2    Lee, H.J.3    Lee, J.K.4    Grace, K.A.5
  • 50
    • 33751217682 scopus 로고    scopus 로고
    • The effect of 24 months of combination statin and extended-release niacin on carotid intima-media thickness: ARBITER 3
    • COI: 1:CAS:528:DC%2BD28XhtlCku7jK
    • Taylor AJ, Lee HJ, Sullenberger LE. The effect of 24 months of combination statin and extended-release niacin on carotid intima-media thickness: ARBITER 3. Curr Med Res Opin. 2006;22(11):2243–50.
    • (2006) Curr Med Res Opin , vol.22 , Issue.11 , pp. 2243-2250
    • Taylor, A.J.1    Lee, H.J.2    Sullenberger, L.E.3
  • 51
    • 70350516769 scopus 로고    scopus 로고
    • Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: a randomized, placebo-controlled, magnetic resonance imaging study
    • COI: 1:CAS:528:DC%2BD1MXhsFSqurvM
    • Lee JM, Robson MD, Yu LM, Shirodaria CC, Cunnington C, Kylintireas I, et al. Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: a randomized, placebo-controlled, magnetic resonance imaging study. J Am Coll Cardiol. 2009;54(19):1787–94.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.19 , pp. 1787-1794
    • Lee, J.M.1    Robson, M.D.2    Yu, L.M.3    Shirodaria, C.C.4    Cunnington, C.5    Kylintireas, I.6
  • 54
    • 68949083513 scopus 로고    scopus 로고
    • Extended-release niacin (nicotinic acid)/laropiprant
    • COI: 1:CAS:528:DC%2BD1MXht1ehtLfE
    • Perry CM. Extended-release niacin (nicotinic acid)/laropiprant. Drugs. 2009;69(12):1665–79.
    • (2009) Drugs , vol.69 , Issue.12 , pp. 1665-1679
    • Perry, C.M.1
  • 55
    • 84886070404 scopus 로고    scopus 로고
    • Relationship of apolipoproteins A-1 and B, and lipoprotein(a) to cardiovascular outcomes: the AIM-HIGH trial (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes)
    • COI: 1:CAS:528:DC%2BC3sXhvVagsL3M
    • Albers JJ, Slee A, O’Brien KD, Robinson JG, Kashyap ML, Kwiterovich Jr PO, et al. Relationship of apolipoproteins A-1 and B, and lipoprotein(a) to cardiovascular outcomes: the AIM-HIGH trial (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes). J Am Coll Cardiol. 2013;62(17):1575–9.
    • (2013) J Am Coll Cardiol , vol.62 , Issue.17 , pp. 1575-1579
    • Albers, J.J.1    Slee, A.2    O’Brien, K.D.3    Robinson, J.G.4    Kashyap, M.L.5    Kwiterovich, P.O.6
  • 56
    • 33846429592 scopus 로고    scopus 로고
    • Drug Insight: mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors
    • COI: 1:CAS:528:DC%2BD2sXhvVWrsb4%3D
    • Gervois P, Fruchart JC, Staels B. Drug Insight: mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors. Nat Clin Pract Endocrinol Metab. 2007;3(2):145–56.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , Issue.2 , pp. 145-156
    • Gervois, P.1    Fruchart, J.C.2    Staels, B.3
  • 57
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial
    • COI: 1:STN:280:DC%2BD2MnjtVCnsg%3D%3D
    • Keech A, Simes RJ, Barter P, Best J, Scott R, Taskinen MR, et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet. 2005;366(9500):1849–61.
    • (2005) Lancet , vol.366 , Issue.9500 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, P.3    Best, J.4    Scott, R.5    Taskinen, M.R.6
  • 58
    • 64749095070 scopus 로고    scopus 로고
    • Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study
    • COI: 1:CAS:528:DC%2BD1MXjvVyqt7s%3D
    • Scott R, O’Brien R, Fulcher G, Pardy C, D’Emden M, Tse D, et al. Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabetes Care. 2009;32(3):493–8.
    • (2009) Diabetes Care , vol.32 , Issue.3 , pp. 493-498
    • Scott, R.1    O’Brien, R.2    Fulcher, G.3    Pardy, C.4    D’Emden, M.5    Tse, D.6
  • 59
    • 77951704587 scopus 로고    scopus 로고
    • Effects of combination lipid therapy in type 2 diabetes mellitus
    • The ACCORD study showed that niacin actually caused harm in diabetics when combined with statins and led to the withdrawal of its use in clinical practice in these patients
    • Group AS, Ginsberg HN, Elam MB, Lovato LC, Crouse 3rd JR, Leiter LA, et al. Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med. 2010;362(17):1563–74. The ACCORD study showed that niacin actually caused harm in diabetics when combined with statins and led to the withdrawal of its use in clinical practice in these patients.
    • (2010) N Engl J Med , vol.362 , Issue.17 , pp. 1563-1574
    • Group, A.S.1    Ginsberg, H.N.2    Elam, M.B.3    Lovato, L.C.4    Crouse, J.R.5    Leiter, L.A.6
  • 60
    • 79960700766 scopus 로고    scopus 로고
    • Efficacy of fibrates for cardiovascular risk reduction in persons with atherogenic dyslipidemia: a meta-analysis
    • COI: 1:CAS:528:DC%2BC3MXps12isr4%3D
    • Lee M, Saver JL, Towfighi A, Chow J, Ovbiagele B. Efficacy of fibrates for cardiovascular risk reduction in persons with atherogenic dyslipidemia: a meta-analysis. Atherosclerosis. 2011;217(2):492–8.
    • (2011) Atherosclerosis , vol.217 , Issue.2 , pp. 492-498
    • Lee, M.1    Saver, J.L.2    Towfighi, A.3    Chow, J.4    Ovbiagele, B.5
  • 61
    • 18244390229 scopus 로고    scopus 로고
    • A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial
    • COI: 1:CAS:528:DC%2BD2MXkslKlsro%3D
    • Pearson TA, Denke MA, McBride PE, Battisti WP, Brady WE, Palmisano J. A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial. Mayo Clin Proc. 2005;80(5):587–95.
    • (2005) Mayo Clin Proc , vol.80 , Issue.5 , pp. 587-595
    • Pearson, T.A.1    Denke, M.A.2    McBride, P.E.3    Battisti, W.P.4    Brady, W.E.5    Palmisano, J.6
  • 62
    • 33845296148 scopus 로고    scopus 로고
    • Ezetimibe/simvastatin vs atorvastatin in patients with type 2 diabetes mellitus and hypercholesterolemia: the VYTAL study
    • COI: 1:CAS:528:DC%2BD2sXhtVGntw%3D%3D
    • Goldberg RB, Guyton JR, Mazzone T, Weinstock RS, Polis A, Edwards P, et al. Ezetimibe/simvastatin vs atorvastatin in patients with type 2 diabetes mellitus and hypercholesterolemia: the VYTAL study. Mayo Clin Proc. 2006;81(12):1579–88.
    • (2006) Mayo Clin Proc , vol.81 , Issue.12 , pp. 1579-1588
    • Goldberg, R.B.1    Guyton, J.R.2    Mazzone, T.3    Weinstock, R.S.4    Polis, A.5    Edwards, P.6
  • 63
  • 64
    • 57449105069 scopus 로고    scopus 로고
    • Effect of statins alone versus statins plus ezetimibe on carotid atherosclerosis in type 2 diabetes: the SANDS (Stop Atherosclerosis in Native Diabetics Study) trial
    • COI: 1:CAS:528:DC%2BD1cXhsFajs7rJ
    • Fleg JL, Mete M, Howard BV, Umans JG, Roman MJ, Ratner RE, et al. Effect of statins alone versus statins plus ezetimibe on carotid atherosclerosis in type 2 diabetes: the SANDS (Stop Atherosclerosis in Native Diabetics Study) trial. J Am Coll Cardiol. 2008;52(25):2198–205.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.25 , pp. 2198-2205
    • Fleg, J.L.1    Mete, M.2    Howard, B.V.3    Umans, J.G.4    Roman, M.J.5    Ratner, R.E.6
  • 65
    • 72049129430 scopus 로고    scopus 로고
    • Extended-release niacin or ezetimibe and carotid intima-media thickness
    • COI: 1:CAS:528:DC%2BD1MXhsFSnsLzP
    • Taylor AJ, Villines TC, Stanek EJ, Devine PJ, Griffen L, Miller M, et al. Extended-release niacin or ezetimibe and carotid intima-media thickness. N Engl J Med. 2009;361(22):2113–22.
    • (2009) N Engl J Med , vol.361 , Issue.22 , pp. 2113-2122
    • Taylor, A.J.1    Villines, T.C.2    Stanek, E.J.3    Devine, P.J.4    Griffen, L.5    Miller, M.6
  • 66
    • 84923184260 scopus 로고    scopus 로고
    • American Heart Association Scientific Sessions, Chicago: The results of IMPROVE IT were presented after significant delays but showed a benefit of adding ezetemibe to statin therapy in patients after acute coronary syndromes. The results for diabetic patients have as yet not been released
    • Cannon CP, IMPROVE-IT trial: a comparison of ezetimibe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes after acute coronary syndromes. Chicago: American Heart Association Scientific Sessions; 2014. The results of IMPROVE IT were presented after significant delays but showed a benefit of adding ezetemibe to statin therapy in patients after acute coronary syndromes. The results for diabetic patients have as yet not been released.
    • (2014) IMPROVE-IT trial: a comparison of ezetimibe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes after acute coronary syndromes
    • Cannon, C.P.1
  • 67
    • 33947583493 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis
    • COI: 1:CAS:528:DC%2BD2sXjs1Ohtro%3D
    • Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Saito Y, Ishikawa Y, et al. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet. 2007;369(9567):1090–8.
    • (2007) Lancet , vol.369 , Issue.9567 , pp. 1090-1098
    • Yokoyama, M.1    Origasa, H.2    Matsuzaki, M.3    Matsuzawa, Y.4    Saito, Y.5    Ishikawa, Y.6
  • 68
    • 77949511855 scopus 로고    scopus 로고
    • Long-term up to 24-month efficacy and safety of concomitant prescription omega-3-acid ethyl esters and simvastatin in hypertriglyceridemic patients
    • COI: 1:CAS:528:DC%2BC3cXjt1Kqsbo%3D
    • Bays HE, Maki KC, McKenney J, Snipes R, Meadowcroft A, Schroyer R, et al. Long-term up to 24-month efficacy and safety of concomitant prescription omega-3-acid ethyl esters and simvastatin in hypertriglyceridemic patients. Curr Med Res Opin. 2010;26(4):907–15.
    • (2010) Curr Med Res Opin , vol.26 , Issue.4 , pp. 907-915
    • Bays, H.E.1    Maki, K.C.2    McKenney, J.3    Snipes, R.4    Meadowcroft, A.5    Schroyer, R.6
  • 69
    • 84897970506 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • The most recent AHA/ACC guidelines suggest statins for all diabetics who are 40 years old or greater. These recommendations have also been echoed by the most recent guidelines of the American Diabetes Association
    • Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;129(25 Suppl 2):S1–45. The most recent AHA/ACC guidelines suggest statins for all diabetics who are 40 years old or greater. These recommendations have also been echoed by the most recent guidelines of the American Diabetes Association.
    • (2014) Circulation , vol.129 , Issue.25 , pp. 1-45
    • Stone, N.J.1    Robinson, J.G.2    Lichtenstein, A.H.3    Bairey Merz, C.N.4    Blum, C.B.5    Eckel, R.H.6
  • 70
    • 79960539641 scopus 로고    scopus 로고
    • ESC/EAS guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
    • Reiner Z, Catapano AL, De Backer G, Graham I, et al. ESC/EAS guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur Heart J. 2011;32(14):1769–818.
    • (2011) Eur Heart J , vol.32 , Issue.14 , pp. 1769-1818
    • Reiner, Z.1    Catapano, A.L.2    De Backer, G.3    Graham, I.4
  • 71
    • 36348975228 scopus 로고    scopus 로고
    • Effects of torcetrapib in patients at high risk for coronary events
    • COI: 1:CAS:528:DC%2BD2sXhtlGns7bL
    • Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007;357(21):2109–22.
    • (2007) N Engl J Med , vol.357 , Issue.21 , pp. 2109-2122
    • Barter, P.J.1    Caulfield, M.2    Eriksson, M.3    Grundy, S.M.4    Kastelein, J.J.5    Komajda, M.6
  • 72
    • 84870045994 scopus 로고    scopus 로고
    • Effects of dalcetrapib in patients with a recent acute coronary syndrome
    • COI: 1:CAS:528:DC%2BC38XhslyltrvK
    • Schwartz GG, Olsson AG, Abt M, Ballantyne CM, Barter PJ, Brumm J, et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012;367(22):2089–99.
    • (2012) N Engl J Med , vol.367 , Issue.22 , pp. 2089-2099
    • Schwartz, G.G.1    Olsson, A.G.2    Abt, M.3    Ballantyne, C.M.4    Barter, P.J.5    Brumm, J.6
  • 73
    • 84891142213 scopus 로고    scopus 로고
    • Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial
    • COI: 1:CAS:528:DC%2BC2cXisVGisrY%3D
    • Nicholls SJ, Kastelein JJ, Schwartz GG, Bash D, Rosenson RS, Cavender MA, et al. Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial. JAMA. 2014;311(3):252–62.
    • (2014) JAMA , vol.311 , Issue.3 , pp. 252-262
    • Nicholls, S.J.1    Kastelein, J.J.2    Schwartz, G.G.3    Bash, D.4    Rosenson, R.S.5    Cavender, M.A.6
  • 74
    • 84878648305 scopus 로고    scopus 로고
    • Proprotein convertase subtilisin kexin 9 (PCSK9) inhibitors in the treatment of hypercholesterolemia and other pathologies
    • COI: 1:CAS:528:DC%2BC3sXovFKhurg%3D
    • Seidah NG. Proprotein convertase subtilisin kexin 9 (PCSK9) inhibitors in the treatment of hypercholesterolemia and other pathologies. Curr Pharm Des. 2013;19(17):3161–72.
    • (2013) Curr Pharm Des , vol.19 , Issue.17 , pp. 3161-3172
    • Seidah, N.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.