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Volumn 240, Issue 1, 2015, Pages 161-162

IMPROVE-IT clinical implications. Should the "high-intensity cholesterol-lowering therapy" strategy replace the "high-intensity statin therapy"?

Author keywords

Ezetimibe; High intensity cholesterol lowering therapy; IMPROVE IT

Indexed keywords

ATORVASTATIN; EZETIMIBE; EZETIMIBE PLUS SIMVASTATIN; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; PITAVASTATIN; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN; BIOLOGICAL MARKER; CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT;

EID: 84928314579     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2015.03.002     Document Type: Note
Times cited : (57)

References (13)
  • 1
    • 84922938167 scopus 로고    scopus 로고
    • IMPROVE-IT trial: a comparison of Ezetimibe/Simvastatin versus simvastatin monotherapy on cardiovascular outcomes after acute coronary syndromes. 2014 late-breaking clinical trial abstracts
    • Cannon, CP on behalf of the IMPROVE IT investigators IMPROVE-IT trial: a comparison of Ezetimibe/Simvastatin versus simvastatin monotherapy on cardiovascular outcomes after acute coronary syndromes. 2014 late-breaking clinical trial abstracts. Circulation 2014, 130:2105-2126.
    • (2014) Circulation , vol.130 , pp. 2105-2126
  • 2
    • 84886019060 scopus 로고    scopus 로고
    • In celebration of the 100th anniversary of the lipid hypothesis of atherosclerosis
    • Steinberg D. In celebration of the 100th anniversary of the lipid hypothesis of atherosclerosis. J.Lipid Res. 2013, 54:2946-2949.
    • (2013) J.Lipid Res. , vol.54 , pp. 2946-2949
    • Steinberg, D.1
  • 3
    • 50949102416 scopus 로고    scopus 로고
    • IMPROVE-IT Investigators. Rationale and design of IMPROVE-IT (IMProved reduction of outcomes: vytorin efficacy international trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes
    • Cannon C.P., Giugliano R.P., Blazing M.A., Harrington R.A., Peterson J.L., Sisk C.M., Strony J., Musliner T.A., McCabe C.H., Veltri E., Braunwald E., Califf R.M. IMPROVE-IT Investigators. Rationale and design of IMPROVE-IT (IMProved reduction of outcomes: vytorin efficacy international trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes. Am. Heart J. 2008, 156:826-832.
    • (2008) Am. Heart J. , vol.156 , pp. 826-832
    • Cannon, C.P.1    Giugliano, R.P.2    Blazing, M.A.3    Harrington, R.A.4    Peterson, J.L.5    Sisk, C.M.6    Strony, J.7    Musliner, T.A.8    McCabe, C.H.9    Veltri, E.10    Braunwald, E.11    Califf, R.M.12
  • 4
    • 84906675153 scopus 로고    scopus 로고
    • Understanding IMPROVE-IT and the cardinal role of LDL-C lowering in CVD prevention
    • Laufs U., Descamps O.S., Catapano A.L., Packard C.J. Understanding IMPROVE-IT and the cardinal role of LDL-C lowering in CVD prevention. Eur. Heart J. 2014, 35:1996-2000.
    • (2014) Eur. Heart J. , vol.35 , pp. 1996-2000
    • Laufs, U.1    Descamps, O.S.2    Catapano, A.L.3    Packard, C.J.4
  • 5
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials
    • Cholesterol Treatment Trialists' (CTT) Collaboration, Baigent C., Blackwell L., Emberson J., Holland L.E., Reith C., Bhala N., Peto R., Barnes E.H., Keech A., Simes J., Collins R. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 2010, 376:1670-1681.
    • (2010) Lancet , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3    Holland, L.E.4    Reith, C.5    Bhala, N.6    Peto, R.7    Barnes, E.H.8    Keech, A.9    Simes, J.10    Collins, R.11
  • 6
    • 18444374227 scopus 로고    scopus 로고
    • Clinical significance of statin pleiotropic effects: hypotheses versus evidence
    • Erratum in Circulation. 2005;112:e126
    • Davidson M.H. Clinical significance of statin pleiotropic effects: hypotheses versus evidence. Circulation 2005, 111:2280-2281. Erratum in Circulation. 2005;112:e126.
    • (2005) Circulation , vol.111 , pp. 2280-2281
    • Davidson, M.H.1
  • 7
    • 84892679366 scopus 로고    scopus 로고
    • OSLER Investigators. Efficacy and safety of longer-term administration of evolocumab (AMG 145) in patients with hypercholesterolemia: 52-week results from the Open-Label study of Long-Term evaluation against LDL-C (OSLER) randomized trial
    • Koren M.J., Giugliano R.P., Raal F.J., Sullivan D., Bolognese M., Langslet G., Civeira F., Somaratne R., Nelson P., Liu T., Scott R., Wasserman S.M., Sabatine M.S. OSLER Investigators. Efficacy and safety of longer-term administration of evolocumab (AMG 145) in patients with hypercholesterolemia: 52-week results from the Open-Label study of Long-Term evaluation against LDL-C (OSLER) randomized trial. Circulation 2014, 129:234-243.
    • (2014) Circulation , vol.129 , pp. 234-243
    • Koren, M.J.1    Giugliano, R.P.2    Raal, F.J.3    Sullivan, D.4    Bolognese, M.5    Langslet, G.6    Civeira, F.7    Somaratne, R.8    Nelson, P.9    Liu, T.10    Scott, R.11    Wasserman, S.M.12    Sabatine, M.S.13
  • 8
    • 0035897696 scopus 로고    scopus 로고
    • Evaluation, and treatment of high blood cholesterol in adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult treatment panel III)
    • Expert Panel on Detection Evaluation, and treatment of high blood cholesterol in adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult treatment panel III). JAMA 2001, 285:2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 9
    • 79960539641 scopus 로고    scopus 로고
    • ESC committee for practice guidelines (CPG) 2008-2010 and 2010-2012 Committees. ESC/EAS guidelines for the management of dyslipidaemias: the task force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
    • European Association for Cardiovascular Prevention & Rehabilitation, Reiner Z., Catapano A.L., De Backer G., Graham I., Taskinen M.R., Wiklund O., Agewall S., Alegria E., Chapman M.J., Durrington P., Erdine S., Halcox J., Hobbs R., Kjekshus J., Filardi P.P., Riccardi G., Storey R.F., Wood D. ESC committee for practice guidelines (CPG) 2008-2010 and 2010-2012 Committees. ESC/EAS guidelines for the management of dyslipidaemias: the task force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur. Heart J. 2011, 32:1769-1818.
    • (2011) Eur. Heart J. , vol.32 , pp. 1769-1818
    • Reiner, Z.1    Catapano, A.L.2    De Backer, G.3    Graham, I.4    Taskinen, M.R.5    Wiklund, O.6    Agewall, S.7    Alegria, E.8    Chapman, M.J.9    Durrington, P.10    Erdine, S.11    Halcox, J.12    Hobbs, R.13    Kjekshus, J.14    Filardi, P.P.15    Riccardi, G.16    Storey, R.F.17    Wood, D.18
  • 10
    • 84893872136 scopus 로고    scopus 로고
    • The year in cardiology 2013: cardiovascular disease prevention
    • Gielen S., Landmesser U. The year in cardiology 2013: cardiovascular disease prevention. Eur. Heart J. 2014, 35:307-312.
    • (2014) Eur. Heart J. , vol.35 , pp. 307-312
    • Gielen, S.1    Landmesser, U.2
  • 11
    • 84893935789 scopus 로고    scopus 로고
    • An international atherosclerosis society position paper: global recommendations for the management of dyslipidemia-full report
    • Expert Dyslipidemia Panel of the International Atherosclerosis Society Panel members An international atherosclerosis society position paper: global recommendations for the management of dyslipidemia-full report. J.Clin. Lipidol. 2014, 8:29-60.
    • (2014) J.Clin. Lipidol. , vol.8 , pp. 29-60
  • 12
    • 84902576469 scopus 로고    scopus 로고
    • American College of Cardiology/American Heart association task force on practice Guidelines. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart association task force on practice Guidelines
    • Erratum in: J Am Coll Cardiol 2014;63:3024-3025
    • Stone N.J., Robinson J.G., Lichtenstein A.H., Bairey Merz C.N., Blum C.B., Eckel R.H., Goldberg A.C., Gordon D., Levy D., Lloyd-Jones D.M., McBride P., Schwartz J.S., Shero S.T., Smith S.C., Watson K., Wilson P.W. American College of Cardiology/American Heart association task force on practice Guidelines. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart association task force on practice Guidelines. J.Am. Coll. Cardiol. 2014, 63:2889-2934. Erratum in: J Am Coll Cardiol 2014;63:3024-3025.
    • (2014) J.Am. Coll. Cardiol. , vol.63 , pp. 2889-2934
    • Stone, N.J.1    Robinson, J.G.2    Lichtenstein, A.H.3    Bairey Merz, C.N.4    Blum, C.B.5    Eckel, R.H.6    Goldberg, A.C.7    Gordon, D.8    Levy, D.9    Lloyd-Jones, D.M.10    McBride, P.11    Schwartz, J.S.12    Shero, S.T.13    Smith, S.C.14    Watson, K.15    Wilson, P.W.16


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