Comparative effectiveness of digoxin and propranolol for supraventricular tachycardia in infants

Pediatric Critical Care Medicine

Volumn 15, Issue 9, 2014, Pages 839-845

  Hornik, Christoph P ^a,b   Chu, Patricia Y ^b   Li, Jennifer S ^a,b   Clark, Reese H ^c   Smith, Phillip Brian ^a,b   Hill, Kevin D ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^c Pediatrix Obstetrix Center for Research and Education   (United States)

Author keywords

Digoxin; Infants; Propranolol; Supraventricular tachycardia

Indexed keywords

ADENOSINE; ADRENALIN; AMIODARONE; ATENOLOL; CREATININE; DIGOXIN; DOBUTAMINE; DOPAMINE; ESMOLOL; FLECAINIDE; INOTROPIC AGENT; MILRINONE; NORADRENALIN; PHENYLEPHRINE; PROPRANOLOL; SOTALOL; UREA; VERAPAMIL; ANTIARRHYTHMIC AGENT;

ARTICLE; BRADYCARDIA; BRONCHOSPASM; CARDIOVERSION; CENTRAL VENOUS CATHETERIZATION; CLINICAL EVALUATION; COHORT ANALYSIS; COMPARATIVE EFFECTIVENESS; COMPLETE HEART BLOCK; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; DRUG EXPOSURE; DRUG SAFETY; DRUG TREATMENT FAILURE; FEMALE; HEART VENTRICLE TACHYCARDIA; HOSPITAL DISCHARGE; HOSPITALIZED INFANT; HUMAN; HYPERCALCEMIA; HYPERKALEMIA; HYPOCALCEMIA; HYPOGLYCEMIA; HYPOKALEMIA; HYPOMAGNESEMIA; HYPOTENSION; INCIDENCE; INFANT; INOTROPISM; INTENSIVE CARE UNIT; KIDNEY DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY (TOPIC); NEWBORN INTENSIVE CARE; OXYGEN THERAPY; PEDIATRIC CARDIOLOGY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENCE RISK; REGISTER; RETROSPECTIVE STUDY; SUPRAVENTRICULAR TACHYCARDIA; TREATMENT OUTCOME; UREA NITROGEN BLOOD LEVEL; COMPARATIVE STUDY; ELECTROCARDIOGRAPHY; MULTIVARIATE ANALYSIS; NEWBORN; PROPORTIONAL HAZARDS MODEL; TACHYCARDIA, SUPRAVENTRICULAR;

ANTI-ARRHYTHMIA AGENTS; DIGOXIN; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MULTIVARIATE ANALYSIS; PROPORTIONAL HAZARDS MODELS; PROPRANOLOL; RETROSPECTIVE STUDIES; TACHYCARDIA, SUPRAVENTRICULAR;

EID: 84928292722     PISSN: 15297535     EISSN: 19473893     Source Type: Journal    
DOI: 10.1097/PCC.0000000000000229     Document Type: Article

References (21)

1. Lundberg A: Paroxysmal tachycardia in infancy. A clinical and experimental study. Acta Paediatr 1963; 52:192-195
2. Nadas AS, Daeschner CW, Roth A, et al: Paroxysmal tachycardia in infants and children; study of 41 cases. Pediatrics 1952; 9:167-181
3. Garson A Jr, Gillette PC: Electrophysiologic studies of supraventricular tachycardia in children. I. Clinical-electrophysiologic correlations. Am Heart J 1981; 102:233-250
4. Salerno JC, Seslar SP: Supraventricular tachycardia. Arch Pediatr Adolesc Med 2009; 163:268-274
5. Wong KK, Potts JE, Etheridge SP, et al: Medications used to manage supraventricular tachycardia in the infant a North American survey. Pediatr Cardiol 2006; 27:199-203
6. Sanatani S, Potts JE, Reed JH, et al: The study of antiarrhythmic medications in infancy (SAMIS): A multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants. Circ Arrhythm Electrophysiol 2012; 5:984-991
7. Perry JC: Supraventricular tachycardia treatment efficacy in infants: On further review. Circ Arrhythm Electrophysiol 2012; 5:882-883
8. Concato J, Shah N, Horwitz RI: Randomized, controlled trials, observational studies, and the hierarchy of research designs. N Engl J Med 2000; 342:1887-1892
9. Spitzer AR, Ellsbury DL, Handler D, et al: The Pediatrix BabySteps Data Warehouse and the Pediatrix QualitySteps improvement project system-tools for "meaningful use" in continuous quality improvement. Clin Perinatol 2010; 37:49-70
10. Olsen IE, Groveman SA, Lawson ML, et al: New intrauterine growth curves based on United States data. Pediatrics 2010; 125:e214-e224
11. Hornik CP, Herring AH, Benjamin DK Jr, et al; Best Pharmaceuticals for Children Act-Pediatric Trials Network: Adverse events associated with meropenem versus imipenem/cilastatin therapy in a large retrospective cohort of hospitalized infants. Pediatr Infect Dis J 2013; 32:748-753
12. O'Sullivan JJ, Gardiner HM, Wren C: Digoxin or flecainide for prophylaxis of supraventricular tachycardia in infants? J Am Coll Cardiol 1995; 26:991-994
13. Tortoriello TA, Snyder CS, Smith EO, et al: Frequency of recurrence among infants with supraventricular tachycardia and comparison of recurrence rates among those with and without preexcitation and among those with and without response to digoxin and/or propranolol therapy. Am J Cardiol 2003; 92:1045-1049
14. Weindling SN, Saul JP, Walsh EP: Efficacy and risks of medical therapy for supraventricular tachycardia in neonates and infants. Am Heart J 1996; 131:66-72
15. Laughon MM, Avant D, Tripathi N, et al: Drug labeling and exposure in neonates. JAMA Pediatr 2014; 168:130-136
16. Li JS, Colan SD, Sleeper LA, et al: Lessons learned from a pediatric clinical trial: The Pediatric Heart Network angiotensin-converting enzyme inhibition in mitral regurgitation study. Am Heart J 2011; 161:233-240
17. Clark RH, Bloom BT, Spitzer AR, et al: Empiric use of ampicillin and cefotaxime, compared with ampicillin and gentamicin, for neonates at risk for sepsis is associated with an increased risk of neonatal death. Pediatrics 2006; 117:67-74
18. Trembath A, Hornik CP, Clark R, et al; Best Pharmaceuticals for Children Act-Pediatric Trials Network: Comparative effectiveness of surfactant preparations in premature infants. J Pediatr 2013; 163:955-960.e1
19. Halkin H, Radomsky M, Blieden L, et al: Steady state serum digoxin concentration in relation to digitalis toxicity in neonates and infants. Pediatrics 1978; 61:184-188
20. Filippi L, Cavallaro G, Fiorini P, et al: Propranolol concentrations after oral administration in term and preterm neonates. J Matern Fetal Neonatal Med 2013; 26:833-840
21. Lang D, von Bernuth G: Serum concentration and serum half-life of digoxin in premature and mature newborns. Pediatrics 1977; 59:902-906