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Volumn 6, Issue 3, 2015, Pages 325-333

Ezetimibe combined with standard diet and exercise therapy improves insulin resistance and atherosclerotic markers in patients with metabolic syndrome

Author keywords

Ezetimibe; Insulin resistance; Metabolic syndrome

Indexed keywords

ANTILIPEMIC AGENT; EZETIMIBE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84928279929     PISSN: 20401116     EISSN: 20401124     Source Type: Journal    
DOI: 10.1111/jdi.12298     Document Type: Article
Times cited : (15)

References (37)
  • 1
    • 0038054346 scopus 로고    scopus 로고
    • Evaluation of efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: a pooled analysis from two controlled phase III clinical studies
    • Knopp RH, Dujovne CA, Le Beaut A, et al. Ezetimibe Study Group. Evaluation of efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: a pooled analysis from two controlled phase III clinical studies. Int J Clin Pract 2003; 57: 363-368.
    • (2003) Int J Clin Pract , vol.57 , pp. 363-368
    • Knopp, R.H.1    Dujovne, C.A.2    Le Beaut, A.3
  • 2
    • 33750390318 scopus 로고    scopus 로고
    • Ezetimibe added to ongoing statin therapy improves LDL-C goal attainment and lipid profile in patients with diabetes or metabolic syndrome
    • Denke M, Pearson T, Mcbride P, et al. Ezetimibe added to ongoing statin therapy improves LDL-C goal attainment and lipid profile in patients with diabetes or metabolic syndrome. Diab Vasc Dis Res 2006; 3: 93-102.
    • (2006) Diab Vasc Dis Res , vol.3 , pp. 93-102
    • Denke, M.1    Pearson, T.2    Mcbride, P.3
  • 3
    • 57649176432 scopus 로고    scopus 로고
    • The effect of statin alone or in combination with ezetimibe on postprandial lipoprotein composition in obese metabolic syndrome patients
    • Hajer GR, Dallinga-Thie GM, van Vark-van der Zee LC, et al. The effect of statin alone or in combination with ezetimibe on postprandial lipoprotein composition in obese metabolic syndrome patients. Atherosclerosis 2009; 202: 216-224.
    • (2009) Atherosclerosis , vol.202 , pp. 216-224
    • Hajer, G.R.1    Dallinga-Thie, G.M.2    van Vark-van der Zee, L.C.3
  • 4
    • 65549092827 scopus 로고    scopus 로고
    • Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles
    • Winkler K, Schewe T, Pütz G, et al. Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles. Eur J Clin Invest 2009; 39: 463-470.
    • (2009) Eur J Clin Invest , vol.39 , pp. 463-470
    • Winkler, K.1    Schewe, T.2    Pütz, G.3
  • 5
    • 67649397411 scopus 로고    scopus 로고
    • Lipid-altering efficacy and safety of ezetimibe/simvastatin versus atorvastatin in patients with hypercholesterolemia and the metabolic syndrome (from the VYMET Study)
    • Robinson JG, Ballantyne CM, Grundy SM, et al. Lipid-altering efficacy and safety of ezetimibe/simvastatin versus atorvastatin in patients with hypercholesterolemia and the metabolic syndrome (from the VYMET Study). Am J Cardiol 2009; 103: 1694-1702.
    • (2009) Am J Cardiol , vol.103 , pp. 1694-1702
    • Robinson, J.G.1    Ballantyne, C.M.2    Grundy, S.M.3
  • 6
    • 77954915745 scopus 로고    scopus 로고
    • Relationships between metabolic syndrome and other baseline factors and the efficacy of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes and hypercholesterolemia
    • Goldberg RB, Guyton JR, Mazzone T, et al. Relationships between metabolic syndrome and other baseline factors and the efficacy of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes and hypercholesterolemia. Diabetes Care 2010; 33: 1021-1024.
    • (2010) Diabetes Care , vol.33 , pp. 1021-1024
    • Goldberg, R.B.1    Guyton, J.R.2    Mazzone, T.3
  • 7
    • 75649136240 scopus 로고    scopus 로고
    • Ezetimibe added to atorvastatin compared with doubling the atorvastatin dose in patients at high risk for coronary heart disease with diabetes mellitus, metabolic syndrome or neither
    • Conard S, Bays H, Leiter LA, et al. Ezetimibe added to atorvastatin compared with doubling the atorvastatin dose in patients at high risk for coronary heart disease with diabetes mellitus, metabolic syndrome or neither. Diabetes Obes Metab 2010; 12: 210-218.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 210-218
    • Conard, S.1    Bays, H.2    Leiter, L.A.3
  • 8
    • 84877651595 scopus 로고    scopus 로고
    • The effects of ezetimibe/simvastatin versus simvastatin monotherapy on platelet and inflammatory biomarkers in patients with metabolic syndrome
    • Miller M, DiNicolantonio JJ, Can M, et al. The effects of ezetimibe/simvastatin versus simvastatin monotherapy on platelet and inflammatory biomarkers in patients with metabolic syndrome. Cardiology 2013; 125: 74-77.
    • (2013) Cardiology , vol.125 , pp. 74-77
    • Miller, M.1    DiNicolantonio, J.J.2    Can, M.3
  • 9
    • 84873435386 scopus 로고    scopus 로고
    • A comparison of efficacy and safety of an ezetimibe/simvastatin combination compared with other intensified lipid-lowering treatment strategies in diabetic patients with symptomatic cardiovascular disease
    • Rosen JB, Jimenez JG, Pirags V, et al. A comparison of efficacy and safety of an ezetimibe/simvastatin combination compared with other intensified lipid-lowering treatment strategies in diabetic patients with symptomatic cardiovascular disease. Diab Vasc Dis Res 2013; 10: 277-286.
    • (2013) Diab Vasc Dis Res , vol.10 , pp. 277-286
    • Rosen, J.B.1    Jimenez, J.G.2    Pirags, V.3
  • 10
    • 79953084081 scopus 로고    scopus 로고
    • Effects of coadministered ezetimibe plus fenofibrate in mixed dyslipidemic patients with metabolic syndrome
    • Bays HE, Shah A, Macdonell G, et al. Effects of coadministered ezetimibe plus fenofibrate in mixed dyslipidemic patients with metabolic syndrome. Metab Syndr Relat Disord 2011; 9: 135-142.
    • (2011) Metab Syndr Relat Disord , vol.9 , pp. 135-142
    • Bays, H.E.1    Shah, A.2    Macdonell, G.3
  • 11
    • 80053091278 scopus 로고    scopus 로고
    • Lipid-altering efficacy of switching to ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk patients with and without metabolic syndrome
    • Averna M, Missault L, Vaverkova H, et al. Lipid-altering efficacy of switching to ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk patients with and without metabolic syndrome. Diab Vasc Dis Res 2011; 8: 262-270.
    • (2011) Diab Vasc Dis Res , vol.8 , pp. 262-270
    • Averna, M.1    Missault, L.2    Vaverkova, H.3
  • 12
    • 84859137880 scopus 로고    scopus 로고
    • Ezetimibe improves glucose metabolism by ameliorating hepatic function in Japanese patients with type 2 diabetes
    • Ichimori S, Shimoda S, Goto R, et al. Ezetimibe improves glucose metabolism by ameliorating hepatic function in Japanese patients with type 2 diabetes. J Diabetes Invest 2012; 3: 179-184.
    • (2012) J Diabetes Invest , vol.3 , pp. 179-184
    • Ichimori, S.1    Shimoda, S.2    Goto, R.3
  • 13
    • 84863554957 scopus 로고    scopus 로고
    • Ezetimibe ameliorates atherosclerotic and inflammatory markers, atherogenic lipid profiles, insulin sensitivity, and liver dysfunction in Japanese patients with hypercholesterolemia
    • Tamaki N, Ueno H, Morinaga Y, et al. Ezetimibe ameliorates atherosclerotic and inflammatory markers, atherogenic lipid profiles, insulin sensitivity, and liver dysfunction in Japanese patients with hypercholesterolemia. J Atheroscler Thromb 2012; 19: 532-538.
    • (2012) J Atheroscler Thromb , vol.19 , pp. 532-538
    • Tamaki, N.1    Ueno, H.2    Morinaga, Y.3
  • 14
    • 77649196152 scopus 로고    scopus 로고
    • Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia
    • Yagi S, Akaike M, Aihara KI, et al. Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia. J Atheroscler Thromb 2010; 17: 173-180.
    • (2010) J Atheroscler Thromb , vol.17 , pp. 173-180
    • Yagi, S.1    Akaike, M.2    Aihara, K.I.3
  • 15
    • 84864381351 scopus 로고    scopus 로고
    • Ezetimibe improves endothelial function and inhibits Rho-kinase activity associated with inhibition of cholesterol absorption in humans
    • Nochioka K, Tanaka S, Miura M, et al. Ezetimibe improves endothelial function and inhibits Rho-kinase activity associated with inhibition of cholesterol absorption in humans. Circ J 2012; 76: 2023-2030.
    • (2012) Circ J , vol.76 , pp. 2023-2030
    • Nochioka, K.1    Tanaka, S.2    Miura, M.3
  • 16
    • 79960806592 scopus 로고    scopus 로고
    • Systolic blood pressure predicts cardiovascular mortality in a farming but not in a fishing community. - A 40-year follow up of the Japanese cohorts of the Seven Countries Study -
    • Hirai Y, Geleijnse JM, Adachi H, et al. Systolic blood pressure predicts cardiovascular mortality in a farming but not in a fishing community. - A 40-year follow up of the Japanese cohorts of the Seven Countries Study -. Circ J 2011; 75: 1890-1896.
    • (2011) Circ J , vol.75 , pp. 1890-1896
    • Hirai, Y.1    Geleijnse, J.M.2    Adachi, H.3
  • 17
    • 4043094921 scopus 로고    scopus 로고
    • Very long chain N-3 fatty acids intake and carotid atherosclerosis: an epidemiological study evaluated by ultrasonography
    • Hino A, Adachi H, Toyomasu K, et al. Very long chain N-3 fatty acids intake and carotid atherosclerosis: an epidemiological study evaluated by ultrasonography. Atherosclerosis 2004; 176: 145-149.
    • (2004) Atherosclerosis , vol.176 , pp. 145-149
    • Hino, A.1    Adachi, H.2    Toyomasu, K.3
  • 18
    • 83155180252 scopus 로고    scopus 로고
    • Plasma aldosterone levels and development of insulin resistance: prospective study in a general population
    • Kumagai E, Adachi H, Jacobs DR Jr, et al. Plasma aldosterone levels and development of insulin resistance: prospective study in a general population. Hypertension 2011; 58: 1043-1048.
    • (2011) Hypertension , vol.58 , pp. 1043-1048
    • Kumagai, E.1    Adachi, H.2    Jacobs Jr, D.R.3
  • 19
    • 84864661734 scopus 로고    scopus 로고
    • Serum hepatocyte growth factor and cancer mortality in an apparently healthy Japanese population
    • Otsuka M, Adachi H, Jacobs DR Jr, et al. Serum hepatocyte growth factor and cancer mortality in an apparently healthy Japanese population. J Epidemiol 2012; 22: 395-401.
    • (2012) J Epidemiol , vol.22 , pp. 395-401
    • Otsuka, M.1    Adachi, H.2    Jacobs Jr, D.R.3
  • 20
    • 84870557718 scopus 로고    scopus 로고
    • Plasma endothelin-1 level is a predictor of 10-year mortality in a general population: the Tanushimaru study
    • Yokoi K, Adachi H, Hirai Y, et al. Plasma endothelin-1 level is a predictor of 10-year mortality in a general population: the Tanushimaru study. Circ J 2012; 76: 2779-2784.
    • (2012) Circ J , vol.76 , pp. 2779-2784
    • Yokoi, K.1    Adachi, H.2    Hirai, Y.3
  • 21
    • 0023002525 scopus 로고
    • Intimal plus medial thickness of the arterial wall: a direct measurements with ultrasound imaging
    • Pignoli P, Tremoli E, Poli A, et al. Intimal plus medial thickness of the arterial wall: a direct measurements with ultrasound imaging. Circulation 1986; 74: 1399-1406.
    • (1986) Circulation , vol.74 , pp. 1399-1406
    • Pignoli, P.1    Tremoli, E.2    Poli, A.3
  • 22
    • 0033858291 scopus 로고    scopus 로고
    • Carotid intima-media thickness in Japanese type 2 diabetic subjects
    • Yamasaki Y, Kodama M, Nishizawa H, et al. Carotid intima-media thickness in Japanese type 2 diabetic subjects. Diabetes Care 2000; 23: 1310-1315.
    • (2000) Diabetes Care , vol.23 , pp. 1310-1315
    • Yamasaki, Y.1    Kodama, M.2    Nishizawa, H.3
  • 23
    • 0027745291 scopus 로고
    • Cholesterol in remnant-like lipoproteins in human serum using monoclonal anti apo B-100 and anti apo A-I immunoaffinity mixed gels
    • Nakajima K, Saito T, Tamura A, et al. Cholesterol in remnant-like lipoproteins in human serum using monoclonal anti apo B-100 and anti apo A-I immunoaffinity mixed gels. Clin Chim Acta 1993; 223: 53-71.
    • (1993) Clin Chim Acta , vol.223 , pp. 53-71
    • Nakajima, K.1    Saito, T.2    Tamura, A.3
  • 24
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 25
    • 33644747113 scopus 로고    scopus 로고
    • The metabolic syndrome: a global public health problem and a new definition
    • Zimmet P, Magliano D, Matsuzawa Y, et al. The metabolic syndrome: a global public health problem and a new definition. J Atheroscler Thromb 2005; 12: 295-300.
    • (2005) J Atheroscler Thromb , vol.12 , pp. 295-300
    • Zimmet, P.1    Magliano, D.2    Matsuzawa, Y.3
  • 26
    • 33644849140 scopus 로고    scopus 로고
    • Metabolic syndrome - Definition and diagnostic criteria in Japan
    • Matsuzawa Y. Metabolic syndrome - Definition and diagnostic criteria in Japan. J Atheroscler Thromb 2005; 12: 301.
    • (2005) J Atheroscler Thromb , vol.12 , pp. 301
    • Matsuzawa, Y.1
  • 27
    • 76249107102 scopus 로고    scopus 로고
    • The effects of ezetimibe on surrogate markers of cholesterol absorption and synthesis in Japanese patients with dyslipidemia
    • Hiramitsu S, Ishiguro Y, Matsuyama H, et al. The effects of ezetimibe on surrogate markers of cholesterol absorption and synthesis in Japanese patients with dyslipidemia. J Atheroscler Thromb 2010; 17: 106-114.
    • (2010) J Atheroscler Thromb , vol.17 , pp. 106-114
    • Hiramitsu, S.1    Ishiguro, Y.2    Matsuyama, H.3
  • 28
    • 84869889959 scopus 로고    scopus 로고
    • Effects of ezetimibe on visceral fat in the metabolic syndrome: a randomized controlled study
    • Takase H, Dohi Y, Okado T, et al. Effects of ezetimibe on visceral fat in the metabolic syndrome: a randomized controlled study. Eur J Clin Invest 2012; 42: 1287-1294.
    • (2012) Eur J Clin Invest , vol.42 , pp. 1287-1294
    • Takase, H.1    Dohi, Y.2    Okado, T.3
  • 29
    • 84857359459 scopus 로고    scopus 로고
    • Effect of ezetimibe on remnant-like particle cholesterol in subjects with metabolic syndrome
    • Kotani K, Sakane N, Taniguchi N. Effect of ezetimibe on remnant-like particle cholesterol in subjects with metabolic syndrome. Med Princ Pract 2012; 21: 134-138.
    • (2012) Med Princ Pract , vol.21 , pp. 134-138
    • Kotani, K.1    Sakane, N.2    Taniguchi, N.3
  • 30
    • 36549013633 scopus 로고    scopus 로고
    • Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome
    • Deushi M, Nomura M, Kawakami A, et al. Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome. FEBS Lett 2007; 581: 5664-5670.
    • (2007) FEBS Lett , vol.581 , pp. 5664-5670
    • Deushi, M.1    Nomura, M.2    Kawakami, A.3
  • 31
    • 37249049393 scopus 로고    scopus 로고
    • The effects of high dose pravastatin and low dose pravastatin and ezetimibe combination therapy on lipid, glucose metabolism and inflammation
    • Dagli N, Yavuzkir M, Karaca I. The effects of high dose pravastatin and low dose pravastatin and ezetimibe combination therapy on lipid, glucose metabolism and inflammation. Inflammation 2007; 30: 230-235.
    • (2007) Inflammation , vol.30 , pp. 230-235
    • Dagli, N.1    Yavuzkir, M.2    Karaca, I.3
  • 32
    • 84871738435 scopus 로고    scopus 로고
    • Double-blind randomized clinical trial of the effects of ezetimibe on postprandial hyperlipidemia and hyperglycaemia
    • Kikuchi K, Nezu U, Inazumi K, et al. Double-blind randomized clinical trial of the effects of ezetimibe on postprandial hyperlipidemia and hyperglycaemia. J Atheroscler Thromb 2012; 19: 1093-1101.
    • (2012) J Atheroscler Thromb , vol.19 , pp. 1093-1101
    • Kikuchi, K.1    Nezu, U.2    Inazumi, K.3
  • 33
    • 84864861863 scopus 로고    scopus 로고
    • Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial
    • Ridker PM, Pradhan A, MacFadyen JG, et al. Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial. Lancet 2012; 380: 565-571.
    • (2012) Lancet , vol.380 , pp. 565-571
    • Ridker, P.M.1    Pradhan, A.2    MacFadyen, J.G.3
  • 34
    • 84455190243 scopus 로고    scopus 로고
    • Ezetimibe monotherapy ameliorates vascular function in patients with hypercholesterolemia through decreasing oxidative stress
    • Kurobe H, Aihara K, Higashida M, et al. Ezetimibe monotherapy ameliorates vascular function in patients with hypercholesterolemia through decreasing oxidative stress. J Atheroscler Thromb 2011; 18: 1080-1089.
    • (2011) J Atheroscler Thromb , vol.18 , pp. 1080-1089
    • Kurobe, H.1    Aihara, K.2    Higashida, M.3
  • 35
    • 84874439177 scopus 로고    scopus 로고
    • Prospective inverse associations of sex hormone concentrations in men with biomarkers of inflammation and oxidative stress
    • Haring R, Baumeister SE, Völzke H, et al. Prospective inverse associations of sex hormone concentrations in men with biomarkers of inflammation and oxidative stress. J Androl 2012; 33: 944-950.
    • (2012) J Androl , vol.33 , pp. 944-950
    • Haring, R.1    Baumeister, S.E.2    Völzke, H.3
  • 36
    • 84870749692 scopus 로고    scopus 로고
    • Dietary cholesterol oxidation products accelerate plaque destabilization and rupture associated with monocyte infiltration/activation via the MCP-1-CCR2 pathway in mouse brachiocephalic arteries: therapeutic effects of Ezetimibe
    • Sato K, Nakano K, Katsuki S, et al. Dietary cholesterol oxidation products accelerate plaque destabilization and rupture associated with monocyte infiltration/activation via the MCP-1-CCR2 pathway in mouse brachiocephalic arteries: therapeutic effects of Ezetimibe. J Atheroscler Thromb 2012; 19: 986-998.
    • (2012) J Atheroscler Thromb , vol.19 , pp. 986-998
    • Sato, K.1    Nakano, K.2    Katsuki, S.3
  • 37
    • 84873304439 scopus 로고    scopus 로고
    • Effect of ezetimibe on major atherosclerotic disease events and all-cause mortality
    • Hayek S, Canepa Escaro F, Sattar A, et al. Effect of ezetimibe on major atherosclerotic disease events and all-cause mortality. Am J Cardiol 2013; 111: 532-539.
    • (2013) Am J Cardiol , vol.111 , pp. 532-539
    • Hayek, S.1    Canepa Escaro, F.2    Sattar, A.3


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