High serum β-lactams specific/total IgE ratio is associated with immediate reactions to β-lactams antibiotics

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Vultaggio, Alessandra ^a   Virgili, Gianni ^b   Gaeta, Francesco ^c   Romano, Antonino ^c   Maggi, Enrico ^b   Matucci, Andrea ^a  

^a Immunoallergology Unit   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c Allergy Unit   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMOXICILLOYL; AMPICILLIN; AMPICILLOYL; BACAMPICILLIN; BETA LACTAM ANTIBIOTIC; DIAGNOSTIC AGENT; IMMUNOGLOBULIN E ANTIBODY; PENICILLIN G; PENICILLOYL G; PENICILLOYL V; PIPERACILLIN; UNCLASSIFIED DRUG; BETA LACTAM; IMMUNOGLOBULIN E;

ADULT; AGED; ANAPHYLAXIS; ANGIONEUROTIC EDEMA; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; MAJOR CLINICAL STUDY; MALE; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SIMULATION; SKIN TEST; URTICARIA; ADOLESCENT; BLOOD; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; BETA-LACTAMS; FEMALE; HUMANS; IMMUNOGLOBULIN E; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84928254089     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121857     Document Type: Article

References (16)

1. Khan DA, Solensky R (2010) Drug allergy. J Allergy Clin Immunol 125:S126-37. doi: 10.1016/j.jaci. 2009.10.028 PMID: 20176256
2. Torres MJ, Blanca M, Fernandez J, Romano A, de Weck A, Aberer W, et al. (2003) ENDA: EAACI Interest Group on Drug Hypersensitivity. Diagnosis of immediate allergic reactions to beta-lactam antibiotics. Allergy 58:961-72. PMID: 14510712
3. Vultaggio A, Matucci A, Virgili G, Rossi O, Filì L, Parronchi P, et al. (2009) Influence of total serum IgE levels on the in vitro detection of β-lactams-specific IgE antibodies. Clin Exp Allergy 39:838-44. doi: 10.1111/j.1365-2222.2009.03219.x PMID: 19400911
4. Kerkhof M, Dubois AEJ, Postma DS, Schouten JP, Monchy JGR (2003) Role and interpretation of total serum IgE measurements in the diagnosis of allergic airway disease in adults. Allergy 58:905-11. PMID: 12911420
5. Jackola DR, Blumenthal MN, Rosenberg A (2004) Evidence for two independent distribution of serum immunoglobulin E in atopic families: cognate and non-cognate IgE. Human Immunol 65:20-30.
6. Matricardi PM, Bockelbrink A, Grüber C, Niggemann B, Hamelmann E, Wahn U, et al. (2009) Longitudinal trends of total and allergen-specific IgE throughout childhood. Allergy 64:1093-98. doi: 10.1111/j. 1398-9995.2009.02055.x PMID: 19630859
7. Ishizaka T, Conrad D, Schulman ES, Sterk AR, Ko CG, Ishizaka K (1984) IgE-mediated triggering signals for mediator release for human mast cells and basophils. Fed Proc 43:2840-45. PMID: 6207053
8. Di Lorenzo G, Mansueto P, Pacor ML, Rizzo M, Castello F, Martinelli N, et al. (2009) Evaluation of serum s-IgE/total IgE ratio in predicting clinical response to allergen-specific immunotherapy. J Allergy Clin Immunol 123:1103-10. doi: 10.1016/j.jaci.2009.02.012 PMID: 19356792
9. Janes H, Pepe MS (2008) Adjusting for covariates in studies of diagnostic, screening, or prognostic markers: An old concept in a new setting. Am J Epidemiol 168:89-97. doi: 10.1093/aje/kwn099 PMID: 18477651
10. Hayen A, Macaskill P, Irwig L, Bossuyt P (2010) Appropriate statistical methods are required to assess diagnostic tests for replacement, add-on, and triage. J Clin Epidemiol 63:883-91. doi: 10.1016/j. jclinepi.2009.08.024 PMID: 20079607
11. Pencina MJ, D'Agostino RB, Pencina KM, Janssens AC, Greenland P (2012) Interpreting incremental value of markers added to risk prediction models. Am J Epidemiol 176:473-81. PMID: 22875755
12. White IR, Royston P, Wood AM (2011) Multiple imputation using chained equations: Issues and guidance for practice. Statistics in Medicine 30: 377-99. doi: 10.1002/sim.4067 PMID: 21225900
13. Johansson SG, Nopp A, Oman H, Ankerst J, Cardell LO, Grönneberg R, et al. (2009) The size of the disease relevant IgE antibody fraction in relation to "total IgE" predicts the efficacy of anti-IgE (Xolair) treatment. Allergy 64:1472-77. doi: 10.1111/j.1398-9995.2009.02051.x PMID: 19393000
14. Federly TJ, Jones BL, Dai H, Dinakar C (2013) Interpretation of food specific immunoglobulin E levels in the context of total IgE. Ann Allergy Asthma Immunol 111:20-24. doi: 10.1016/j.anai.2013.05.012 PMID: 23806455
15. Johansson SGO, Adedoyn J, van Hage M, Gronneber R, Noop A (2013) False-positive penicillin immunoassay: An unoticed common problem. J Allergy Clin Immunol 132:235-37. doi: 10.1016/j.jaci.2012. 11.017 PMID: 23270810
16. Rutjes AW, Reitsma JB, Vandenbroucke JP, Glas AS, Bossuyt PM (2005) Case-control and two-gate designs in diagnostic accuracy studies. Clin Chem 51:1335-41. PMID: 15961549