Changes in the cerebrospinal fluid circulatory system of the developing rat: Quantitative volumetric analysis and effect on blood-CSF permeability interpretation

Fluids and Barriers of the CNS

Volumn 12, Issue 1, 2015, Pages

  Ghersi Egea, Jean François ^a,b   Babikian, Anaïd ^a   Blondel, Sandrine ^a   Strazielle, Nathalie ^b,c  

^a INSERM   (France)

^b LYON NEUROSCIENCE RESEARCH CENTER   (France)

^c Brain i   (France)

Author keywords

Blood brain barrier; Claudin; Embryo; Influx constant; Meninges; Postnatal development; Subarachnoid space; Ventricle

Indexed keywords

CLAUDIN 1; CLAUDIN 5;

ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID PERMEABILITY; BRAIN DEVELOPMENT; BRAIN VENTRICLE; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID FLOW; CEREBROSPINAL FLUID TO BRAIN VOLUME RATIO; CEREBROSPINAL FLUID TO CRANIAL CAVITY VOLUME RATIO; CHOROID PLEXUS; CISTERNA MAGNA; CISTERNAL SPACE; CONTROLLED STUDY; EMBRYO; FEMALE; FETUS; FLUORESCENCE; IMMUNOHISTOCHEMISTRY; NERVOUS SYSTEM PARAMETERS; NEWBORN; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SPRAGUE DAWLEY RAT; TIGHT JUNCTION; VENTRICULAR SPACE; VOLUMETRY;

EID: 84928227020     PISSN: None     EISSN: 20458118     Source Type: Journal    
DOI: 10.1186/s12987-015-0001-2     Document Type: Article

References (26)

1. Kivisakk P, Mahad DJ, Callahan MK, Trebst C, Tucky B, Wei T, et al. Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin. Proc Natl Acad Sci U S A. 2003;100:8389-94.
2. Onaivi ES, Schanz N, Lin ZC. Psychiatric disturbances regulate the innate immune system in CSF of conscious mice. Transl Psychiatry. 2014;4:e367.
3. Schmitt C, Strazielle N, Ghersi-Egea JF. Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain. J Neuroinflammation. 2012;9:187.
4. Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta. Sci Transl Med. 2012;4:147ra111.
5. Redzic ZB, Preston JE, Duncan JA, Chodobski A, Szmydynger-Chodobska J. The choroid plexus-cerebrospinal fluid system: from development to aging. Curr Top Dev Biol. 2005;71:1-52.
6. Chodobski A, Silverberg G, Szmydynger-Chodobska J. The role of the choroid plexus in transport and production of polypeptides. In: Zeng W, Chodobski A, editors. The blood-cerebrospinal fluid barrier. Boca Raton, Fl, USA: CRC Press; 2005 p. 237-74.
7. Schmitt C, Strazielle N, Richaud P, Bouron A, Ghersi-Egea JF. Active transport at the blood-CSF barrier contributes to manganese influx into the brain. J Neurochem. 2011;117:747-56.
8. Ghersi-Egea JF, Finnegan W, Chen JL, Fenstermacher JD. Rapid distribution of intraventricularly administered sucrose into cerebrospinal fluid cisterns via subarachnoid velae in rat. Neuroscience. 1996;75:1271-88.
9. Badaut J, Ghersi-Egea JF. The choroid plexus and cerebrospinal fluid system: roles in neurodegenerative diseases. In: Neman J, Chen TC, editors. The choroid plexus and cerebrospinal fluid: emerging roles in CNS development, maintenance, and disease progression. San Diego: Elsevier/Academic Press; 2014 in press.
10. Kratzer I, Liddelow SA, Saunders NR, Dziegielewska KM, Strazielle N, Ghersi-Egea JF. Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection. Fluids Barriers CNS. 2013;10:25.
11. Liddelow SA, Dziegielewska KM, Ek CJ, Habgood MD, Bauer H, Bauer HC, et al. Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach. PLoS One. 2013;8:e65629.
12. Strazielle N, Ghersi-Egea JF. Physiology of blood-brain interfaces in relation to brain disposition of small compounds and macromolecules. Mol Pharm. 2013;10:1473-91.
13. Kratzer I, Vasiljevic A, Rey C, Fevre-Montange M, Saunders N, Strazielle N, et al. Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier. Histochem Cell Biol. 2012;138:861-79.
14. Jones HC, Andersohn RW. Progressive changes in cortical water and electrolyte content at three stages of rat infantile hydrocephalus and the effect of shunt treatment. Exp Neurol. 1998;154:126-36.
15. Normand G, Clos J, Vincendon G, Gombos G. Postnatal development of rat cerebellum: glycosaminoglycan changes related to variation in water content, cell formation and organ growth. Int J Dev Neurosci. 1985;3:245-56.
16. Peterson GL. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem. 1977;83:346-56.
17. Ek CJ, Habgood MD, Dziegielewska KM, Potter A, Saunders NR. Permeability and route of entry for lipid-insoluble molecules across brain barriers in developing Monodelphis domestica. J Physiol. 2001;536:841-53.
18. Harris NG, Jones HC, Williams SC. MR imaging for measurements of ventricles and cerebral cortex in postnatal rats (H-Tx strain) with progressive inherited hydrocephalus. Exp Neurol. 1992;118:1-6.
19. Ghersi-Egea JF, Gorevic PD, Ghiso J, Frangione B, Patlak CS, Fenstermacher JD. Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J Neurochem. 1996;67:880-3.
20. Wright R, Kyriakopoulou V, Ledig C, Rutherford MA, Hajnal JV, Rueckert D, et al. Automatic quantification of normal cortical folding patterns from fetal brain MRI. Neuroimage. 2014;91:21-32.
21. Ennis SR, Keep RF. The effects of cerebral ischemia on the rat choroid plexus. J Cereb Blood Flow Metab. 2006;26:675-83.
22. Nehlig A, Pereira de Vasconcelos A, Boyet S. Postnatal changes in local cerebral blood flow measured by the quantitative autoradiographic [14C] iodoantipyrine technique in freely moving rats. J Cereb Blood Flow Metab. 1989;9:579-88.
23. Pereira de Vasconcelos A, Ferrandon A, Nehlig A. Local cerebral blood flow during lithium-pilocarpine seizures in the developing and adult rat: role of coupling between blood flow and metabolism in the genesis of neuronal damage. J Cereb Blood Flow Metab. 2002;22:196-205.
24. Johansson PA, Dziegielewska KM, Liddelow SA, Saunders NR. The blood-CSF barrier explained: when development is not immaturity. Bioessays. 2008;30:237-48.
25. Habgood MD, Knott GW, Dziegielewska KM, Saunders NR. The nature of the decrease in blood-cerebrospinal fluid barrier exchange during postnatal brain development in the rat. J Physiol. 1993;468:73-83.
26. Johansson PA, Dziegielewska KM, Ek CJ, Habgood MD, Liddelow SA, Potter AM, et al. Blood-CSF barrier function in the rat embryo. Eur J Neurosci. 2006;24:65-76.