Ceftaroline CSF concentrations in a patient with ventriculoperitoneal shunt-related meningitis

Journal of Antimicrobial Chemotherapy

Volumn 70, Issue 3, 2015, Pages 953-954

  Kuriakose, Safia S ^a   Rabbat, Mohamed ^a   Gallagher, Jason C ^b  

^a ST JOSEPH S REGIONAL MEDICAL CENTER   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF PHARMACY   (United States)

Author keywords

Cephalosporins; CNS; MRSA

Indexed keywords

CEFAZOLIN; CEFTAROLINE; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; CREATININE; GENTAMICIN; LINEZOLID; MEROPENEM; NAFCILLIN; VANCOMYCIN; ANTIINFECTIVE AGENT;

ACTIVE TRANSPORT; AREA UNDER THE CURVE; BLOOD CULTURE; BLOOD SAMPLING; BRAIN VENTRICLE PERITONEUM SHUNT; CEREBROSPINAL FLUID CULTURE; COMPUTER ASSISTED TOMOGRAPHY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG PROTEIN BINDING; HUMAN; HYDROCEPHALUS; HYDROPHILICITY; LETHARGY; LETTER; LIPOPHILICITY; MENINGITIS; MENINX; MENTAL HEALTH; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN-RESISTANT STAPHYLOCOCCUS EPIDERMIDIS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR SIZE; NONHUMAN; OBSTRUCTIVE HYDROCEPHALUS; PLASMA PROTEIN BINDING; RABBIT MODEL; SERRATIA INFECTION; SERRATIA MARCESCENS; SHUNT INFECTION; STAPHYLOCOCCUS INFECTION; SURGICAL PATIENT; TREATMENT DURATION; TREATMENT FAILURE; VENTRICULOSTOMY CATHETER; VOLUME OF DISTRIBUTION; ADVERSE EFFECTS; CASE REPORT; CEREBROSPINAL FLUID; CHEMISTRY; MENINGITIS, BACTERIAL; PLASMA;

ANTI-BACTERIAL AGENTS; CEPHALOSPORINS; CEREBROSPINAL FLUID; HUMANS; MENINGITIS, BACTERIAL; PLASMA; VENTRICULOPERITONEAL SHUNT;

EID: 84928177565     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dku464     Document Type: Letter

References (8)

1. Saravolatz LD, Stein GE, Johnson LB. Ceftaroline: a novel cephalosporin with activity against methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2011; 52: 1156-63.
2. Polenakovik HM, Pleiman CM. Ceftaroline for meticillin-resistant Staphylococcus aureus bacteraemia: case series and review of the literature. Int J Antimicrob Agents 2013; 42: 450-5.
3. Ho TT, Cadena J, Childs LM et al. Methicillin-resistant Staphylococcus aureus bacteraemia and endocarditis treated with ceftaroline salvage therapy. J Antimicrob Chemother 2012; 67: 1267-70.
4. Jongsma K, Joson J, Heidari A. Ceftaroline in the treatment of concomitant methicillin-resistant and daptomycin-non-susceptible Staphylococcus aureus infective endocarditis and osteomyelitis: case report. J Antimicrob Chemother 2013; 68: 1444-5.
5. Bucheit J, Collins R, Joshi P. Methicillin-resistant Staphylococcus aureus epidural abscess treated with ceftaroline fosamil salvage therapy. Am J Health Syst Pharm 2014; 71: 110-3.
6. Cottagnoud P, Cottagnoud M, Acosta F et al. Efficacy of ceftaroline fosamil against penicillin-sensitive and -resistant Streptococcus pneumoniae in an experimental rabbit meningitis model. Antimicrob Agents Chemother 2013; 57: 4653-5.
7. Stucki A, Acosta F, Cottagnoud M et al. Efficacy of ceftaroline fosamil against Escherichia coli and Klebsiella pneumoniae strains in a rabbit meningitis model. Antimicrob Agents Chemother 2013; 57:5808-10.
8. Nau R, Sorgel F, Eiffert H. Penetration of drugs through the bloodcerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections. Clin Microbiol Rev 2013; 23: 858-83.