메뉴 건너뛰기




Volumn 11, Issue , 2015, Pages 469-474

Ranolazine versus placebo in patients with ischemic cardiomyopathy and persistent chest pain or dyspnea despite optimal medical and revascularization therapy: Randomized, double-blind crossover pilot study

Author keywords

Angina; Controlled study; Ischemic heart disease; Microvascular disease; Reduced ejection fraction

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIANGINA PECTORIS AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PLACEBO; RANOLAZINE;

EID: 84928156724     PISSN: 11766336     EISSN: 1178203X     Source Type: Journal    
DOI: 10.2147/TCRM.S82288     Document Type: Article
Times cited : (6)

References (12)
  • 1
    • 84859793723 scopus 로고    scopus 로고
    • Comparison of clinical characteristics and long-term outcomes of patients with ischemic cardiomyopathy with versus without angina pectoris (from the Duke Databank for Cardiovascular Disease)
    • Mentz RJ, Fiuzat M, Shaw LK, et al. Comparison of clinical characteristics and long-term outcomes of patients with ischemic cardiomyopathy with versus without angina pectoris (from the Duke Databank for Cardiovascular Disease). Am J Cardiol. 2012;109(9):1272–1277.
    • (2012) Am J Cardiol , vol.109 , Issue.9 , pp. 1272-1277
    • Mentz, R.J.1    Fiuzat, M.2    Shaw, L.K.3
  • 2
    • 0030746244 scopus 로고    scopus 로고
    • Response of symptomatic myocardial ischemia in ischemic cardio-myopathy to intensive vasodilator therapy
    • Levine TB, Levine AB, Vincenzi A, Keteyian SJ, Billings J, Lesch M. Response of symptomatic myocardial ischemia in ischemic cardio-myopathy to intensive vasodilator therapy. Am J Cardiol. 1997;80(2): 212–214.
    • (1997) Am J Cardiol , vol.80 , Issue.2 , pp. 212-214
    • Levine, T.B.1    Levine, A.B.2    Vincenzi, A.3    Keteyian, S.J.4    Billings, J.5    Lesch, M.6
  • 3
    • 0020036633 scopus 로고
    • Pathophysiology of chest pain in patients with cardiomyopathies and normal coronary arteries
    • Pasternac A, Noble J, Streulens Y, Elie R, Henschke C, Bourassa MG. Pathophysiology of chest pain in patients with cardiomyopathies and normal coronary arteries. Circulation. 1982;654:778–789.
    • (1982) Circulation , vol.654 , pp. 778-789
    • Pasternac, A.1    Noble, J.2    Streulens, Y.3    Elie, R.4    Henschke, C.5    Bourassa, M.G.6
  • 4
    • 11144356285 scopus 로고    scopus 로고
    • MARISA Investigators. Anti-ischemic effects and long-term survival during ranolazine mono-therapy in patients with chronic severe angina
    • Chaitman BR, Skettino SL, Parker JO, et al; MARISA Investigators. Anti-ischemic effects and long-term survival during ranolazine mono-therapy in patients with chronic severe angina. J Am Coll Cardiol. 2004;43(8):1375–1382.
    • (2004) J am Coll Cardiol , vol.43 , Issue.8 , pp. 1375-1382
    • Chaitman, B.R.1    Skettino, S.L.2    Parker, J.O.3
  • 5
    • 0348129532 scopus 로고    scopus 로고
    • Combination Assessment of Ranolazine In Stable Angina (CARISA) Investigators. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: A randomized controlled trial
    • Chaitman BR, Pepine CJ, Parker JO, et al; Combination Assessment of Ranolazine In Stable Angina (CARISA) Investigators. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. JAMA. 2004;291(3):309–316.
    • (2004) JAMA , vol.291 , Issue.3 , pp. 309-316
    • Chaitman, B.R.1    Pepine, C.J.2    Parker, J.O.3
  • 6
    • 33745000050 scopus 로고    scopus 로고
    • MERLIN-TIMI 36 Investigators. Evaluation of a novel anti-ischemic agent in acute coronary syndromes: Design and rationale for the Metabolic Effciency with Ranolazine for Less Ischemia in Non-ST-elevation acute coronary syndromes (MERLIN)-TIMI 36 trial
    • Morrow DA, Scirica BM, Karwatowska-Prokopczuk E, Skene A, McCabe CH, Braunwald E; MERLIN-TIMI 36 Investigators. Evaluation of a novel anti-ischemic agent in acute coronary syndromes: design and rationale for the Metabolic Effciency with Ranolazine for Less Ischemia in Non-ST-elevation acute coronary syndromes (MERLIN)-TIMI 36 trial. Am Heart J. 2006;151(6):1186.e1–1186.e9.
    • (2006) Am Heart J , vol.151 , Issue.6 , pp. e1-1186
    • Morrow, D.A.1    Scirica, B.M.2    Karwatowska-Prokopczuk, E.3    Skene, A.4    McCabe, C.H.5    Braunwald, E.6
  • 7
    • 0036645419 scopus 로고    scopus 로고
    • Health status predicts long-term outcome in outpatients with coronary disease
    • Spertus JA, Jones P, McDonell M, Fan V, Fihn SD. Health status predicts long-term outcome in outpatients with coronary disease. Circulation. 2002;106(1):43–49.
    • (2002) Circulation , vol.106 , Issue.1 , pp. 43-49
    • Spertus, J.A.1    Jones, P.2    McDonell, M.3    Fan, V.4    Fihn, S.D.5
  • 9
    • 33144470708 scopus 로고    scopus 로고
    • Inhibition of late (sustained/ persistent) sodium current: A potential drug target to reduce intracellular sodium-dependent calcium overload and its detrimental effects on car-diomyocyte function
    • Belardinelli L, Antzelevitch C, Fraser H. Inhibition of late (sustained/ persistent) sodium current: a potential drug target to reduce intracellular sodium-dependent calcium overload and its detrimental effects on car-diomyocyte function. Eur Heart J Suppl. 2004;6(Suppl 1):S13–S17.
    • (2004) Eur Heart J Suppl , vol.6 , pp. S13-S17
    • Belardinelli, L.1    Antzelevitch, C.2    Fraser, H.3
  • 10
    • 0037162348 scopus 로고    scopus 로고
    • Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium
    • Pieske B, Maier LS, Piacentino V, Weisser J, Hasenfuss G, Houser S. Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium. Circulation. 2002;106(4):447–453.
    • (2002) Circulation , vol.106 , Issue.4 , pp. 447-453
    • Pieske, B.1    Maier, L.S.2    Piacentino, V.3    Weisser, J.4    Hasenfuss, G.5    Houser, S.6
  • 11
    • 33845284849 scopus 로고    scopus 로고
    • Ca2+/calmodulin-dependentprotein kinase II regulates cardiac Na+ channels
    • Wagner S, Dybkova N, Rasenack EC, et al. Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. J Clin Invest. 2006; 116(12):3127–3138.
    • (2006) J Clin Invest , vol.116 , Issue.12 , pp. 3127-3138
    • Wagner, S.1    Dybkova, N.2    Rasenack, E.C.3
  • 12
    • 84871692739 scopus 로고    scopus 로고
    • American College of Cardiology Foundation/American Heart Association Task Force. 2012 ACCF/ AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons
    • Fihn SD, Gardin JM, Abrams J, et al; American College of Cardiology Foundation/American Heart Association Task Force. 2012 ACCF/ AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation. 2012;126(25):e354–e471.
    • (2012) Circulation , vol.126 , Issue.25 , pp. e354-e471
    • Fihn, S.D.1    Gardin, J.M.2    Abrams, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.