Review: In renal impairment, apixaban reduces, or does not increase, bleeding compared with other anticoagulants

Annals of Internal Medicine

Volumn 162, Issue 8, 2015, Pages JC3-

  Ribic, Christine M ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIVITAMIN K; APIXABAN; CREATININE; DABIGATRAN; ENOXAPARIN; PLACEBO; WARFARIN; BLOOD CLOTTING FACTOR 10A INHIBITOR; PYRAZOLE DERIVATIVE; PYRIDONE DERIVATIVE;

ALBUMINURIA; ANTICOAGULANT THERAPY; ATRIAL FIBRILLATION; BLEEDING; CREATININE CLEARANCE; DRUG SAFETY; FOLLOW UP; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FAILURE; KIDNEY FUNCTION; MILD RENAL IMPAIRMENT; NOTE; PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEVERE RENAL IMPAIRMENT; VENOUS THROMBOEMBOLISM; CHEMICALLY INDUCED; COMPLICATION; STROKE;

ATRIAL FIBRILLATION; FACTOR XA INHIBITORS; HEMORRHAGE; HUMANS; PYRAZOLES; PYRIDONES; RENAL INSUFFICIENCY; STROKE; VENOUS THROMBOEMBOLISM;

EID: 84928139940     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/ACPJC-2015-162-8-003     Document Type: Note

References (4)

1. Connolly SJ, Ezekowitz MD, Yusuf S, et al; RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009;361:1139-51.
2. Hernandez I, Baik SH, Piñera A, Zhang Y. Risk of bleeding with dabigatran in atrial fibrillation. JAMA Intern Med. 2015;175:18-24.
3. Jun. M, James MT, Manns BJ, et al; Alberta Kidney Disease Network. The association between kidney function and major bleeding in older adults with atrial fibrillation starting warfarin treatment: population based observational study. BMJ. 2015;350:h246.
4. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International Supplements. 2013;3:1-150.