Origins of cystic fibrosis lung disease

New England Journal of Medicine

Volumn 372, Issue 16, 2015, Pages 1574-1575

  Munder, Antje ^a   Tümmler, Burkhard ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; CHLORIDE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR;

ACIDIFICATION; BONE MARROW CELL; CELL MEMBRANE; CELL TRANSPORT; CYSTIC FIBROSIS; EPITHELIUM CELL; HUMAN; LETTER; LUNG DISEASE; MACROPHAGE; MONOCYTE; MUCOCILIARY TRANSPORT; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; PSEUDOMONAS AERUGINOSA; RESPIRATORY EPITHELIUM; ANIMAL; GENETICS; LUNG; PATHOLOGY; ANTIMICROBIAL ACTIVITY; INFECTION; INFLAMMATION; NEUTROPHIL; PATHOGENESIS; SMOOTH MUSCLE FIBER;

ANIMALS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; LUNG;

EID: 84928014771     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc1502191     Document Type: Letter

References (5)

1. Stoltz DA, Meyerholz DK, Welsh MJ. Origins of cystic fibrosis lung disease. N Engl J Med 2015;372:351-62.
2. Del Porto P, Cifani N, Guarnieri S, et al. Dysfunctional CFTR alters the bactericidal activity of human macrophages against Pseudomonas aeruginosa. PLoS One 2011;6(5):e19970.
3. Van de Weert-van Leeuwen PB, Van Meegen MA, Speirs JJ, et al. Optimal complement-mediated phagocytosis of Pseudomonas aeruginosa by monocytes is cystic fibrosis transmembrane conductance regulator-dependent. Am J Respir Cell Mol Biol 2013; 49:463-70.
4. Ng HP, Zhou Y, Song K, Hodges CA, Drumm ML, Wang G. Neutrophil-mediated phagocytic host defense defect in myeloid Cftr-inactivated mice. PLoS One 2014;9(9):e106813.
5. Bonfield TL, Hodges CA, Cotton CU, Drumm ML. Absence of the cystic fibrosis transmembrane regulator (Cftr) from myeloidderived cells slows resolution of inflammation and infection. J Leukoc Biol 2012;92:1111-22.