Preserved Na/HCO3 cotransporter sensitivity to insulin may promote hypertension in metabolic syndrome

Kidney International

Volumn 87, Issue 3, 2015, Pages 535-542

  Nakamura, Motonobu ^a   Yamazaki, Osamu ^a   Shirai, Ayumi ^a   Horita, Shoko ^a   Satoh, Nobuhiko ^a   Suzuki, Masashi ^a   Hamasaki, Yoshifumi ^a   Noiri, Eisei ^a   Kume, Haruki ^a   Enomoto, Yutaka ^a   Homma, Yukio ^a   Seki, George ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

insulin resistance; IRS1; IRS2; NBCe1; proximal tubule; siRNA

Indexed keywords

BICARBONATE SODIUM COTRANSPORTER; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; PHOSPHATIDYLINOSITOL 3 KINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, RAT; IRS2 PROTEIN, RAT; MESSENGER RNA; SREBF1 PROTEIN, RAT;

ADIPOCYTE; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN VERSUS ANIMAL COMPARISON; HYPERTENSION; INSULIN RESISTANCE; INSULIN SENSITIVITY; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; MALE; METABOLIC SYNDROME X; NONHUMAN; OBESITY; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SODIUM TRANSPORT; ANIMAL; DRUG EFFECTS; GENE SILENCING; GENETICS; LIVER; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SIGNAL TRANSDUCTION; WISTAR RAT;

ADIPOCYTES; AGED; ANIMALS; FEMALE; GENE SILENCING; GLUCOSE; HUMANS; HYPERTENSION; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; KIDNEY CORTEX; KIDNEY TUBULES, PROXIMAL; LIVER; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASE; RATS; RATS, INBRED OLETF; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; SODIUM-BICARBONATE SYMPORTERS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84928006369     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2014.351     Document Type: Article

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