Effect of CD4+ cell count and viral suppression on risk of ischemic stroke in HIV infection

AIDS

Volumn 28, Issue 17, 2014, Pages 2573-2577

  Chow, Felicia C ^a   Bacchetti, Peter ^b   Kim, Anthony S ^a   Price, Richard W ^a   Hsue, Priscilla Y ^b  

^a SAN FRANCISCO GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cerebrovascular disease; HIV; Immunodeficiency; Ischemic stroke; Viral suppression

Indexed keywords

CD4 ANTIGEN; VIRUS RNA;

ADULT; AGED; ARTICLE; BRAIN ISCHEMIA; CASE CONTROL STUDY; CELL COUNT; CONTROLLED STUDY; DISEASE ASSOCIATION; DYSLIPIDEMIA; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERTENSION; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; VIRUS INHIBITION; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; COMPLICATION; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOLOGY; ISOLATION AND PURIFICATION; MIDDLE AGED; STROKE; VIROLOGY; VIRUS LOAD;

ADULT; AGED; CASE-CONTROL STUDIES; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; HIV; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; RISK ASSESSMENT; STROKE; VIRAL LOAD;

EID: 84927741564     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0000000000000452     Document Type: Article

References (9)

1. Chow FC. Regan S. Feske S. Meigs JB. Grinspoon SK. Triant VA. Comparison of ischemic stroke incidence in HIV-infected and non-HIV-infected patients in a US Healthcare System. J Acquir Immune Defic Syndr 2012; 60: 351-358.
2. Rasmussen LD. Engsig FN. Christensen H. Gerstoft J. Kronborg G. Pedersen C. et al. Risk of cerebrovascular events in persons with and without HIV. AIDS 2011; 25: 1637-1646.
3. Vinikoor MJ. Napravnik S. Floris-Moore M. Wilson S. Huang DY. Eron JJ. Incidence and clinical features of cerebrovascular disease among HIV-infected adults in the Southeastern United States. AIDS Res Hum Retroviruses 2013; 29: 1068-1074.
4. Mateen FJ. Post WS. Sacktor N. Abraham AG. Becker JT. Smith BR. et al. Long-term predictive value of the Framingham Risk Score for Stroke in HIV-positive vs HIV-negative men. Neurology 2013; 81: 2094-2102.
5. Sabin CA. Ryom L. De Wit S. Mocroft A. Phillips AN. Worm SW. et al. Associations between immune depression and cardiovascular events in HIV infection. AIDS 2013; 27: 2735-2748.
6. WHO MONICA Project Principal Investigators. The World Health Organization MONICA Project (Monitoring Trends and Determinants in Cardiovascular Disease): a major international collaboration. J Clin Epidemiol 1988; 41: 105-114.
7. Adams HP. Bendixen BH. Kappelle LJ. Biller J. Love BB. Gordon DL. et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993; 24: 35-41.
8. Marcus JL. Leyden WA. Chao CR. Chow FC. Horberg MA. Hurley LB. et al. HIV infection and incidence of ischemic stroke. AIDS 2014; 28: 1911-1919.
9. Chow FC. He W. Bacchetti P. Regan S. Feske SF. Meigs JB. et al. Elevated rates of intracerebral hemorrhage in individuals from a U.S. clinical care HIV cohort. Neurology (in press).