Presynaptic neuromuscular action of a methanolic extract from the venom of Rhinella schneideri toad

Journal of Venomous Animals and Toxins Including Tropical Diseases

Volumn 20, Issue 1, 2014, Pages

  Rostelato Ferreira, Sandro ^a   Dal Belo, Cháriston A ^b   Leite, Gildo B ^a   Hyslop, Stephen ^a   Rodrigues Simioni, Léa ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSIDADE FEDERAL DO PAMPA   (Brazil)

Author keywords

Neurotransmitter release; Ouabain; Presynaptic; Rhinella schneideri; Toad venom

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMPHIBIAN VENOM; OUABAIN; RHINELLA SCHNEIDERI VENOM; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ANIMAL TISSUE; ANURA; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; IN VITRO STUDY; MALE; MEMBRANE STEADY POTENTIAL; MINIATURE ENDPLATE POTENTIAL; MOUSE; MUSCLE TWITCH; NEUROTOXICITY; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRESYNAPTIC POTENTIAL; RHINELLA SCHNEIDERI;

ANIMALIA; ANURA; STROPHANTHUS GRATUS;

EID: 84927734486     PISSN: 16789180     EISSN: 16789199     Source Type: Journal    
DOI: 10.1186/1678-9199-20-30     Document Type: Article

References (24)

1. Daly JW, Witkop B. The venoms of amphibians. Mem Inst Butantan 1966, 33(2):425-432.
2. Toledo RC, Jared C, Brunner Junior A. Morphology of the large granular alveoli of the parotid glands in toad (Bufo ictericus) before and after compression. Toxicon 1992, 30(7):745-753. 10.1016/0041-0101(92)90008-S, 1509492.
3. Chen KK, Kovaríková A. Pharmacology and toxicology of toad venom. J Pharm Sci 1967, 56(12):1535-1541. 10.1002/jps.2600561202, 4871915.
4. Sakate M, Oliveira PCL. Toad envenoming in dogs: effects and treatment. J Venom Anim Toxins 2000, 6(1):52-62. [http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000100003].
5. Camplesi CA. Avaliações clínicas e laboratoriais da intoxicação experimental por veneno de sapo em cães. MSc Dissertation 2006, 103. Botucatu: Universidade Estadual Paulista - UNESP, Faculdade de Medicina Veterinária e Zootecnia.
6. Frost D. Amphibian species of the world: an online reference, version 5.4. [http://research.amnh.org/vz/herpetology/amphibia/Amphibia/Anura/Bufonidae/Rhinella/Rhinella-schneideri]. 2009 Available at. Accessed 2 Feb 2010.
7. Riet F. Consideraciones sobre la farmacología y toxicología del veneno deBufo paracnemisLutz. An Fac Vet 1966, 11(9):17-29. láms. 1-5. Montevideo.
8. Gao H, Zehl M, Leitner A, Wu X, Wang Z, Kopp B. Comparison of toad venoms from differentBufospecies by HPLC and LC-DAD-MS/MS. J Ethnopharmacol 2010, 131(2):368-376. 10.1016/j.jep.2010.07.017, 20637273.
9. Bülbring E. Observations on the isolated phrenic nerve diaphragm preparation of the rat. Br J Pharmacol Chemother 1946, 1(1):38-61. 10.1111/j.1476-5381.1946.tb00025.x, 1509711, 20999334.
10. Prior C, Dempster J, Marshall G. Electrophysiological analysis of transmission at the skeletal neuromuscular junction. J Pharmacol Toxicol Methods 1983, 30(1):1-17.
11. Dal Belo CA, Leite GB, Toyama MH, Marangoni S, Corrado AP, Fontana MD, Southan A, Rowan EG, Hyslop S, Rodrigues-Simioni L. Pharmacological and structural characterization of a novel phospholipase A2 fromMicrurus dumerilii carinicaudavenom. Toxicon 2005, 46(7):736-750. 10.1016/j.toxicon.2005.07.016, 16198388.
12. Maeno T, Hara N, Enomoto K, Ichinose M, Sawada M. Effects of inhibitors of ouabain-sensitive Na+, K(+)-ATPase and Li+ions on the neuromuscular transmission of the frog. Jpn J Physiol 1995, 45(3):397-410. 10.2170/jjphysiol.45.397, 7474524.
13. Rostelato-Ferreira S, Dal Belo CA, Cruz-Höfling MA, Hyslop S, Rodrigues-Simioni L. Presynaptic effect of a methanolic extract of toad (Rhinella schneideri) poison in avian neuromuscular preparation. J Venom Res 2011, 2:32-36. 3189579, 21994808.
14. Lundh H, Schiller HH, Elmqvist D. Correlation between single fibre EMG jitter and endplate potentials studied in mild experimental botulinum poisoning. Acta Neurol Scand 1977, 56(2):141-152.
15. Rodrigues-Simioni L, Silva-Carvalho I, Heluany NF, Leite GB, Prado-Franceschi J, Cruz-Höfling MA, Ballejo G, Corrado AP. Novel effects of guanidine on the neuromuscular junction. Gen Pharmacol 1997, 28(4):599-605. 10.1016/S0306-3623(96)00229-7, 9147031.
16. Fatt P, Katz B. An analysis of the end-plate potential recorded with an intracellular electrode. J Physiol 1951, 115(3):320-370. 1392060, 14898516.
17. Haimann C, Torri-Tarelli F, Fesce R, Ceccarelli B. Measurement of quantal secretion induced by ouabain and its correlation with depletion of synaptic vesicles. J Cell Biol 1985, 101(5 Pt 1):1953-1965. 2113948, 3932368.
18. Balezina OP, Lapteva VI. Digoxin facilitates neuromuscular transmission in mouse diaphragm. Bull Exp Biol Med 2007, 144(4):487-490. 10.1007/s10517-007-0357-7, 18642693.
19. Zelnik R. A natureza química do veneno de sapo. Ciênc Cult 1965, 17:10-14.
20. Brownlee AA, Johnson P, Mills IH. Actions of bufalin and cinobufotalin, two bufadienolides respectively more active and less active than ouabain, on ouabain binding and86Rb uptake by human erytrocytes. Clin Sci 1990, 78(2):169-174.
21. Krivoi II, Drabkina TM, Kravtsova VV, Vasiliev NA, Eaton MJ, Skatchkov SN, Mandel F. On the functional interaction between nicotinic acetylcholine receptor and Na+, K+-ATPase. Pflugers Arch 2006, 452(6):756-765. 10.1007/s00424-006-0081-6, 16636868.
22. Nikol'skii EE, Bukharaeva EA, Badrutdinov LR. The effects of carbacholine on spontaneous quantum secretion of mediator from frog motor nerve endings in the presence of ouabain and in a potassium-free medium. Neirofiziologiia 1989, 21(4):558-561. [Article in Russian].
23. Busse F, Lullmann H, Peters T. Concentration dependence of the binding of ouabain to isolated guinea pig atria. J Cardiovasc Pharmacol 1979, 1(6):687-698. 10.1097/00005344-197911000-00009, 94634.
24. Krivoi II. Mechanisms of the non-neurotransmitter actions of acetylcholine in the neuromuscular apparatus. Neurosci Behav Physiol 2002, 32(2):149-156. 10.1023/A:1013975324963, 11942694.