Acute idiopathic transverse myelitis in children: Early predictors of relapse and disability

Neurology

Volumn 84, Issue 4, 2015, Pages 341-349

  Deiva, Kumaran ^a   Absoud, Michael ^b   Hemingway, Cheryl ^c   Hernandez, Yaiza ^b   Hussson, Béatrice ^d   Maurey, Hélène ^a   Niotakis, Giorgios ^c   Wassmer, Evangeline ^e   Lim, Ming ^b   Tardieu, Marc ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^d BICÊTRE HOSPITAL   (France)

^e BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM;

ACUTE DISEASE; ADOLESCENT; AMERICAN SPINAL INJURY ASSOCIATION IMPAIRMENT SCALE; ARTICLE; BRAIN DAMAGE; CENTRAL NERVOUS SYSTEM DISEASE; CHILD; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DEMYELINATING DISEASE; DISABILITY; EXPANDED DISABILITY STATUS SCALE; FEMALE; FOLLOW UP; HUMAN; IDIOPATHIC DISEASE; INFANT; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; MYELITIS; MYELOOPTIC NEUROPATHY; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PLEOCYTOSIS; PRIORITY JOURNAL; RELAPSE; SEX; CLINICAL TRIAL; MULTICENTER STUDY; MYELITIS, TRANSVERSE; NEUROMYELITIS OPTICA; PRESCHOOL CHILD; PROGNOSIS; RECURRENT DISEASE; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SEX DIFFERENCE;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DISABILITY EVALUATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; MALE; MULTIPLE SCLEROSIS; MYELITIS, TRANSVERSE; NEUROMYELITIS OPTICA; PROGNOSIS; RECURRENCE; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX FACTORS;

EID: 84927645179     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000001179     Document Type: Article

References (30)

1. Wolf VL, Lupo PJ, Lotze TE. Pediatric acute transverse myelitis overview and differential diagnosis. J Child Neurol 2012;27:1426-1436.
2. Ketelslegers IA, Catsman-Berrevoets CE, Neuteboom RF, et al. Incidence of acquired demyelinating syndromes of the CNS in Dutch children: a nationwide study. J Neurol 2012;259:1929-1935.
3. De Goede CG, Holmes EM, Pike MG. Acquired transverse myelopathy in children in the United Kingdom: a 2-year prospective study. Eur J Paediatr Neurol 2010;14:479-487.
4. Transverse Myelitis Consortium Working Group. Proposed diagnostic criteria and nosology of acute transverse myelitis. Neurology 2002;59:499-505.
5. Pidcock FS, Krishnan C, Crawford TO, Salorio CF, Trovato M, Kerr DA. Acute transverse myelitis in childhood: center-based analysis of 47 cases. Neurology 2007; 68:1474-1480.
6. Kalra V, Sharma S, Sahu J, et al. Childhood acute transverse myelitis: clinical profile, outcome, and association with antiganglioside antibodies. J Child Neurol 2009;24: 466-471.
7. Thomas T, Branson HM, Verhey LH, et al. The demographic, clinical, and magnetic resonance imaging (MRI) features of transverse myelitis in children. J Child Neurol 2012;27:11-21.
8. Alper G, Petropoulou KA, Fitz CR, Kim Y. Idiopathic acute transverse myelitis in children: an analysis and discussion of MRI findings. Mult Scler 2011;17:74-80.
9. DaJusta DG, Wosnitzer MS, Barone JG. Persistent motor deficits predict long-term bladder dysfunction in children following acute transverse myelitis. J Urol 2008;180: 1774-1777.
10. Yiu EM, Kornberg AJ, Ryan MM, Coleman LT, Mackay MT. Acute transverse myelitis and acute disseminated encephalomyelitis in childhood: spectrum or separate entities? J Child Neurol 2009;24:287-296.
11. Defresne P, Hollenberg H, Husson B, et al. Acute transverse myelitis in children: clinical course and prognostic factors. J Child Neurol 2003;18:401-406.
12. Cobo Calvo A,ManeMartinezMA, Alentorn-Palau A, Bruna Escuer J, Romero Pinel L, Martinez-Yelamos S. Idiopathic acute transverse myelitis: outcome and conversion to multiple sclerosis in a large series. BMC Neurol 2013;13:135.
13. Krupp LB, Tardieu M, Amato MP, et al. International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions. Mult Scler 2013;19:1261-1267.
14. Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006;66:1485-1489.
15. Maynard FM Jr, Bracken MB, Creasey G, et al. International standards for neurological and functional classification of spinal cord injury: American Spinal Injury Association. Spinal Cord 1997;35:266-274.
16. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-1452.
17. Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 2011;69:292-302.
18. Royston P, Moons KG, Altman DG, Vergouwe Y. Prognosis and prognostic research: Developing a prognostic model. BMJ 2009;338:b604.
19. Mikaeloff Y, Adamsbaum C, Husson B, et al. MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhood. Brain 2004;127:1942-1947.
20. Young J, Quinn S, Hurrell M, Taylor B. Clinically isolated acute transverse myelitis: prognostic features and incidence. Mult Scler 2009;15:1295-1302.
21. Jacobs LD, Beck RW, Simon JH, et al. Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group. N Engl J Med 2000;343:898-904.
22. Bruna J, Martinez-Yelamos S, Martinez-Yelamos A, Rubio F, Arbizu T. Idiopathic acute transverse myelitis: a clinical study and prognostic markers in 45 cases. Mult Scler 2006;12: 169-173.
23. Scott TF, Frohman EM, De Seze J, et al. Evidencebased guideline: clinical evaluation and treatment of transverse myelitis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2011;77:2128-2134.
24. Meyer P, Leboucq N, Molinari N, et al. Partial acute transverse myelitis is a predictor of multiple sclerosis in children. Mult Scler 2014;20:1485-1493.
25. Banwell B, Ghezzi A, Bar-Or A, Mikaeloff Y, Tardieu M. Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions. Lancet Neurol 2007;6: 887-902.
26. Hacohen Y, Absoud M, Woodhall M, et al. Autoantibody biomarkers in childhood-acquired demyelinating syndromes: results from a national surveillance cohort. J Neurol Neurosurg Psychiatry 2014;85:456-461.
27. Kitley J, Waters P, Woodhall M, et al. Neuromyelitis optica spectrum disorders with aquaporin-4 and myelinoligodendrocyte glycoprotein antibodies: a comparative study. JAMA Neurol 2014;71:276-283.
28. Graves DE, Frankiewicz RG, Donovan WH. Construct validity and dimensional structure of the ASIA motor scale. J Spinal Cord Med 2006;29:39-45.
29. Kipp M, Berger K, Clarner T, Dang J, Beyer C. Sex steroids control neuroinflammatory processes in the brain: relevance for acute ischaemia and degenerative demyelination. J Neuroendocrinol 2012;24:62-70.
30. Nedeltchev K, Loher TJ, Stepper F, et al. Long-term outcome of acute spinal cord ischemia syndrome. Stroke 2004;35:560-565.