-
1
-
-
67549125238
-
Gene expression profiling of the tumor microenvironment during breast cancer progression
-
Ma XJ, Dahiya S, Richardson E, et al. Gene expression profiling of the tumor microenvironment during breast cancer progression. Breast Cancer Res 2009; 11:R7.
-
(2009)
Breast Cancer Res
, vol.11
, pp. R7
-
-
Ma, X.J.1
Dahiya, S.2
Richardson, E.3
-
2
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumor microenvironment
-
Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 2012; 21:309-322.
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
3
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005; 121:335-348.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
-
4
-
-
33644826473
-
Roots and stems: Stem cells in cancer
-
Polyak K, Hahn WC. Roots and stems: stem cells in cancer. Nat Med 2006; 12:296-300.
-
(2006)
Nat Med
, vol.12
, pp. 296-300
-
-
Polyak, K.1
Hahn, W.C.2
-
5
-
-
36048947234
-
Breast cancer: Origins and evolution
-
Polyak K. Breast cancer: origins and evolution. J Clin Invest 2007; 117:3155-3163.
-
(2007)
J Clin Invest
, vol.117
, pp. 3155-3163
-
-
Polyak, K.1
-
6
-
-
78049529766
-
Extracellular matrix composition reveals complex and dynamic stromal-epithelial interactions in the mammary gland
-
Maller O, Martinson H, Schedin P. Extracellular matrix composition reveals complex and dynamic stromal-epithelial interactions in the mammary gland. J Mammary Gland Biol Neoplasia 2010; 15:301-318.
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 301-318
-
-
Maller, O.1
Martinson, H.2
Schedin, P.3
-
7
-
-
77950099096
-
Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast
-
Bauer M, Su G, Casper C, et al. Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast. Oncogene 2010; 29:1732-1740.
-
(2010)
Oncogene
, vol.29
, pp. 1732-1740
-
-
Bauer, M.1
Su, G.2
Casper, C.3
-
8
-
-
70949103794
-
Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model
-
Liao D, Luo Y, Markowitz D, et al. Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model. PLoS One 2009; 4:e7965.
-
(2009)
PLoS One
, vol.4
, pp. e7965
-
-
Liao, D.1
Luo, Y.2
Markowitz, D.3
-
9
-
-
84862313154
-
Cancer-associated-fibroblasts and tumour cells: A diabolic liaison driving cancer progression
-
Cirri P, Chiarugi P. Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression. Cancer Metastasis Rev 2012; 31:195-208.
-
(2012)
Cancer Metastasis Rev
, vol.31
, pp. 195-208
-
-
Cirri, P.1
Chiarugi, P.2
-
10
-
-
84884368877
-
Influence of tumour micro-environment heterogeneity on therapeutic response
-
Junttila MR, de Sauvage FJ. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 2013; 501:346-354.
-
(2013)
Nature
, vol.501
, pp. 346-354
-
-
Junttila, M.R.1
De Sauvage, F.J.2
-
11
-
-
84866784798
-
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
-
DeNardo DG, Brennan DJ, Rexhepaj E, et al. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov 2011; 1:54-67.
-
(2011)
Cancer Discov
, vol.1
, pp. 54-67
-
-
Denardo, D.G.1
Brennan, D.J.2
Rexhepaj, E.3
-
12
-
-
38949202980
-
Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
-
Bergamaschi A, Tagliabue E, Sorlie T, et al. Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome. J Pathol 2008; 214:357-367.
-
(2008)
J Pathol
, vol.214
, pp. 357-367
-
-
Bergamaschi, A.1
Tagliabue, E.2
Sorlie, T.3
-
13
-
-
84874165459
-
Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress
-
Triulzi T, Casalini P, Sandri M, et al. Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress. PLoS One 2013; 8:e56761.
-
(2013)
PLoS One
, vol.8
, pp. e56761
-
-
Triulzi, T.1
Casalini, P.2
Sandri, M.3
-
14
-
-
19344363035
-
Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds
-
Chang HY, Sneddon JB, Alizadeh AA, et al. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol 2004; 2:E7.
-
(2004)
PLoS Biol
, vol.2
, pp. E7
-
-
Chang, H.Y.1
Sneddon, J.B.2
Alizadeh, A.A.3
-
15
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
Finak G, Bertos N, Pepin F, et al. Stromal gene expression predicts clinical outcome in breast cancer. Nature Med 2008; 14:518-527.
-
(2008)
Nature Med
, vol.14
, pp. 518-527
-
-
Finak, G.1
Bertos, N.2
Pepin, F.3
-
16
-
-
0024549349
-
Induction of angiogenesis during the transition from hyperplasia to neoplasia
-
Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989; 339:58-61.
-
(1989)
Nature
, vol.339
, pp. 58-61
-
-
Folkman, J.1
Watson, K.2
Ingber, D.3
Hanahan, D.4
-
17
-
-
0024547916
-
Successful treatment of an angiogenic disease
-
Folkman J. Successful treatment of an angiogenic disease. N Engl J Med 1989; 320:1211-1212.
-
(1989)
N Engl J Med
, vol.320
, pp. 1211-1212
-
-
Folkman, J.1
-
18
-
-
84855912001
-
Pericyte depletion results in hypoxiaassociated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway
-
Cooke VG, LeBleu VS, Keskin D, et al. Pericyte depletion results in hypoxiaassociated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell 2012; 21:66-81.
-
(2012)
Cancer Cell
, vol.21
, pp. 66-81
-
-
Cooke, V.G.1
Lebleu, V.S.2
Keskin, D.3
-
19
-
-
84857640591
-
Cancer associated fibroblasts: The dark side of the coin
-
Cirri P, Chiarugi P. Cancer associated fibroblasts: the dark side of the coin. Am J Cancer Res 2011; 1:482-497.
-
(2011)
Am J Cancer Res
, vol.1
, pp. 482-497
-
-
Cirri, P.1
Chiarugi, P.2
-
20
-
-
79953309908
-
Tumour-associated fibroblasts and mesenchymal stem cells: More similarities than differences
-
Paunescu V, Bojin FM, Tatu CA, et al. Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differences. J Cell Mol Med 2011; 15:635-646.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 635-646
-
-
Paunescu, V.1
Bojin, F.M.2
Tatu, C.A.3
-
21
-
-
42549152045
-
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
-
Qiu W, Hu M, Sridhar A, et al. No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas. Nat Genet 2008; 40:650-655.
-
(2008)
Nat Genet
, vol.40
, pp. 650-655
-
-
Qiu, W.1
Hu, M.2
Sridhar, A.3
-
22
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev 2012; 12:252-264.
-
(2012)
Nat Rev
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
23
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H, Strome SE, Salomao DR, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8:793-800.
-
(2002)
Nat Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
-
24
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366:2443-2454.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
25
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012; 366:2455-2465.
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
26
-
-
79955570584
-
Anti-ErbB-2 mAb therapy requires type i and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy
-
Stagg J, Loi S, Divisekera U, et al. Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy. Proc Natl Acad Sci U S A 2011; 108:7142-7147.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 7142-7147
-
-
Stagg, J.1
Loi, S.2
Divisekera, U.3
-
27
-
-
84857883847
-
Macrophage plasticity and polarization: In vivo veritas
-
Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 2012; 122:787-795.
-
(2012)
J Clin Invest
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
29
-
-
84927170707
-
Successes and limitations of targeted cancer therapy in breast cancer
-
Curigliano G, Criscitiello C. Successes and limitations of targeted cancer therapy in breast cancer. Prog Tumor Res 2014; 41:15-35.
-
(2014)
Prog Tumor Res
, vol.41
, pp. 15-35
-
-
Curigliano, G.1
Criscitiello, C.2
-
30
-
-
84879108302
-
GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors
-
Morandi A, Martin LA, Gao Q, et al.GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors. Cancer Res 2013; 73:3783-3795.
-
(2013)
Cancer Res
, vol.73
, pp. 3783-3795
-
-
Morandi, A.1
Martin, L.A.2
Gao, Q.3
-
31
-
-
81555210940
-
Antiestrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells
-
Martinez-Outschoorn UE, Goldberg A, Lin Z, et al. Antiestrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells. Cancer Biol Ther 2011; 12:924-938.
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 924-938
-
-
Martinez-Outschoorn, U.E.1
Goldberg, A.2
Lin, Z.3
-
32
-
-
58149334773
-
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
-
Farmer P, Bonnefoi H, Anderle P, et al. A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. Nat Med 2009; 15:68-74.
-
(2009)
Nat Med
, vol.15
, pp. 68-74
-
-
Farmer, P.1
Bonnefoi, H.2
Anderle, P.3
|