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Volumn 26, Issue 6, 2014, Pages 551-555

Tumor-stroma crosstalk: Targeting stroma in breast cancer

Author keywords

Breast cancer; Microenvironment; Tumor stroma

Indexed keywords

ANGIOGENESIS; BREAST METASTASIS; CANCER GROWTH; CELL IMMORTALIZATION; CELL PROLIFERATION; ENDOTHELIUM CELL; ENERGY METABOLISM; EXTRACELLULAR MATRIX; FIBROBLAST; HOST CELL; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; MACROPHAGE; MEDIATOR RELEASE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; STROMA CELL; TUMOR INVASION; TUMOR MICROENVIRONMENT; ANIMAL; BREAST TUMOR; FEMALE; PATHOLOGY; PHYSIOLOGY;

EID: 84927619757     PISSN: 10408746     EISSN: 1531703X     Source Type: Journal    
DOI: 10.1097/CCO.0000000000000122     Document Type: Review
Times cited : (52)

References (32)
  • 1
    • 67549125238 scopus 로고    scopus 로고
    • Gene expression profiling of the tumor microenvironment during breast cancer progression
    • Ma XJ, Dahiya S, Richardson E, et al. Gene expression profiling of the tumor microenvironment during breast cancer progression. Breast Cancer Res 2009; 11:R7.
    • (2009) Breast Cancer Res , vol.11 , pp. R7
    • Ma, X.J.1    Dahiya, S.2    Richardson, E.3
  • 2
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: Functions of cells recruited to the tumor microenvironment
    • Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 2012; 21:309-322.
    • (2012) Cancer Cell , vol.21 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 3
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005; 121:335-348.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3
  • 4
    • 33644826473 scopus 로고    scopus 로고
    • Roots and stems: Stem cells in cancer
    • Polyak K, Hahn WC. Roots and stems: stem cells in cancer. Nat Med 2006; 12:296-300.
    • (2006) Nat Med , vol.12 , pp. 296-300
    • Polyak, K.1    Hahn, W.C.2
  • 5
    • 36048947234 scopus 로고    scopus 로고
    • Breast cancer: Origins and evolution
    • Polyak K. Breast cancer: origins and evolution. J Clin Invest 2007; 117:3155-3163.
    • (2007) J Clin Invest , vol.117 , pp. 3155-3163
    • Polyak, K.1
  • 6
    • 78049529766 scopus 로고    scopus 로고
    • Extracellular matrix composition reveals complex and dynamic stromal-epithelial interactions in the mammary gland
    • Maller O, Martinson H, Schedin P. Extracellular matrix composition reveals complex and dynamic stromal-epithelial interactions in the mammary gland. J Mammary Gland Biol Neoplasia 2010; 15:301-318.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 301-318
    • Maller, O.1    Martinson, H.2    Schedin, P.3
  • 7
    • 77950099096 scopus 로고    scopus 로고
    • Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast
    • Bauer M, Su G, Casper C, et al. Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast. Oncogene 2010; 29:1732-1740.
    • (2010) Oncogene , vol.29 , pp. 1732-1740
    • Bauer, M.1    Su, G.2    Casper, C.3
  • 8
    • 70949103794 scopus 로고    scopus 로고
    • Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model
    • Liao D, Luo Y, Markowitz D, et al. Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model. PLoS One 2009; 4:e7965.
    • (2009) PLoS One , vol.4 , pp. e7965
    • Liao, D.1    Luo, Y.2    Markowitz, D.3
  • 9
    • 84862313154 scopus 로고    scopus 로고
    • Cancer-associated-fibroblasts and tumour cells: A diabolic liaison driving cancer progression
    • Cirri P, Chiarugi P. Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression. Cancer Metastasis Rev 2012; 31:195-208.
    • (2012) Cancer Metastasis Rev , vol.31 , pp. 195-208
    • Cirri, P.1    Chiarugi, P.2
  • 10
    • 84884368877 scopus 로고    scopus 로고
    • Influence of tumour micro-environment heterogeneity on therapeutic response
    • Junttila MR, de Sauvage FJ. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 2013; 501:346-354.
    • (2013) Nature , vol.501 , pp. 346-354
    • Junttila, M.R.1    De Sauvage, F.J.2
  • 11
    • 84866784798 scopus 로고    scopus 로고
    • Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
    • DeNardo DG, Brennan DJ, Rexhepaj E, et al. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov 2011; 1:54-67.
    • (2011) Cancer Discov , vol.1 , pp. 54-67
    • Denardo, D.G.1    Brennan, D.J.2    Rexhepaj, E.3
  • 12
    • 38949202980 scopus 로고    scopus 로고
    • Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
    • Bergamaschi A, Tagliabue E, Sorlie T, et al. Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome. J Pathol 2008; 214:357-367.
    • (2008) J Pathol , vol.214 , pp. 357-367
    • Bergamaschi, A.1    Tagliabue, E.2    Sorlie, T.3
  • 13
    • 84874165459 scopus 로고    scopus 로고
    • Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress
    • Triulzi T, Casalini P, Sandri M, et al. Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress. PLoS One 2013; 8:e56761.
    • (2013) PLoS One , vol.8 , pp. e56761
    • Triulzi, T.1    Casalini, P.2    Sandri, M.3
  • 14
    • 19344363035 scopus 로고    scopus 로고
    • Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds
    • Chang HY, Sneddon JB, Alizadeh AA, et al. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol 2004; 2:E7.
    • (2004) PLoS Biol , vol.2 , pp. E7
    • Chang, H.Y.1    Sneddon, J.B.2    Alizadeh, A.A.3
  • 15
    • 43249121177 scopus 로고    scopus 로고
    • Stromal gene expression predicts clinical outcome in breast cancer
    • Finak G, Bertos N, Pepin F, et al. Stromal gene expression predicts clinical outcome in breast cancer. Nature Med 2008; 14:518-527.
    • (2008) Nature Med , vol.14 , pp. 518-527
    • Finak, G.1    Bertos, N.2    Pepin, F.3
  • 16
    • 0024549349 scopus 로고
    • Induction of angiogenesis during the transition from hyperplasia to neoplasia
    • Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989; 339:58-61.
    • (1989) Nature , vol.339 , pp. 58-61
    • Folkman, J.1    Watson, K.2    Ingber, D.3    Hanahan, D.4
  • 17
    • 0024547916 scopus 로고
    • Successful treatment of an angiogenic disease
    • Folkman J. Successful treatment of an angiogenic disease. N Engl J Med 1989; 320:1211-1212.
    • (1989) N Engl J Med , vol.320 , pp. 1211-1212
    • Folkman, J.1
  • 18
    • 84855912001 scopus 로고    scopus 로고
    • Pericyte depletion results in hypoxiaassociated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway
    • Cooke VG, LeBleu VS, Keskin D, et al. Pericyte depletion results in hypoxiaassociated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell 2012; 21:66-81.
    • (2012) Cancer Cell , vol.21 , pp. 66-81
    • Cooke, V.G.1    Lebleu, V.S.2    Keskin, D.3
  • 19
    • 84857640591 scopus 로고    scopus 로고
    • Cancer associated fibroblasts: The dark side of the coin
    • Cirri P, Chiarugi P. Cancer associated fibroblasts: the dark side of the coin. Am J Cancer Res 2011; 1:482-497.
    • (2011) Am J Cancer Res , vol.1 , pp. 482-497
    • Cirri, P.1    Chiarugi, P.2
  • 20
    • 79953309908 scopus 로고    scopus 로고
    • Tumour-associated fibroblasts and mesenchymal stem cells: More similarities than differences
    • Paunescu V, Bojin FM, Tatu CA, et al. Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differences. J Cell Mol Med 2011; 15:635-646.
    • (2011) J Cell Mol Med , vol.15 , pp. 635-646
    • Paunescu, V.1    Bojin, F.M.2    Tatu, C.A.3
  • 21
    • 42549152045 scopus 로고    scopus 로고
    • No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
    • Qiu W, Hu M, Sridhar A, et al. No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas. Nat Genet 2008; 40:650-655.
    • (2008) Nat Genet , vol.40 , pp. 650-655
    • Qiu, W.1    Hu, M.2    Sridhar, A.3
  • 22
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev 2012; 12:252-264.
    • (2012) Nat Rev , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 23
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • Dong H, Strome SE, Salomao DR, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8:793-800.
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3
  • 24
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366:2443-2454.
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 25
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012; 366:2455-2465.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 26
    • 79955570584 scopus 로고    scopus 로고
    • Anti-ErbB-2 mAb therapy requires type i and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy
    • Stagg J, Loi S, Divisekera U, et al. Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy. Proc Natl Acad Sci U S A 2011; 108:7142-7147.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 7142-7147
    • Stagg, J.1    Loi, S.2    Divisekera, U.3
  • 27
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: In vivo veritas
    • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 2012; 122:787-795.
    • (2012) J Clin Invest , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 28
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • Mantovani A, Cassatella MA, Costantini C, Jaillon S. Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 2011; 11:519-531.
    • (2011) Nat Rev Immunol , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 29
    • 84927170707 scopus 로고    scopus 로고
    • Successes and limitations of targeted cancer therapy in breast cancer
    • Curigliano G, Criscitiello C. Successes and limitations of targeted cancer therapy in breast cancer. Prog Tumor Res 2014; 41:15-35.
    • (2014) Prog Tumor Res , vol.41 , pp. 15-35
    • Curigliano, G.1    Criscitiello, C.2
  • 30
    • 84879108302 scopus 로고    scopus 로고
    • GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors
    • Morandi A, Martin LA, Gao Q, et al.GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors. Cancer Res 2013; 73:3783-3795.
    • (2013) Cancer Res , vol.73 , pp. 3783-3795
    • Morandi, A.1    Martin, L.A.2    Gao, Q.3
  • 31
    • 81555210940 scopus 로고    scopus 로고
    • Antiestrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells
    • Martinez-Outschoorn UE, Goldberg A, Lin Z, et al. Antiestrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells. Cancer Biol Ther 2011; 12:924-938.
    • (2011) Cancer Biol Ther , vol.12 , pp. 924-938
    • Martinez-Outschoorn, U.E.1    Goldberg, A.2    Lin, Z.3
  • 32
    • 58149334773 scopus 로고    scopus 로고
    • A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
    • Farmer P, Bonnefoi H, Anderle P, et al. A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. Nat Med 2009; 15:68-74.
    • (2009) Nat Med , vol.15 , pp. 68-74
    • Farmer, P.1    Bonnefoi, H.2    Anderle, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.