Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding

Science

Volumn 348, Issue 6231, 2015, Pages 242-245

  Xue, Yali ^a   Prado Martinez, Javier ^b   Sudmant, Peter H ^c   Narasimhan, Vagheesh ^a,d   Ayub, Qasim ^a   Szpak, Michal ^a   Frandsen, Peter ^e   Chen, Yuan ^a   Yngvadottir, Bryndis ^a   Cooper, David N ^f   De Manuel, Marc ^b   Hernandez Rodriguez, Jessica ^b   Lobon, Irene ^b   Siegismund, Hans R ^e   Pagani, Luca ^a,g   Quail, Michael A ^a   Hvilsom, Christina ^h   Mudakikwa, Antoine ⁱ   Eichler, Evan E ^c,j   Cranfield, Michael R ^k   Marques Bonet, Tomas ^b,l   Tyler Smith, Chris ^a   Scally, Aylwyn ^m   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f CARDIFF UNIVERSITY   (United Kingdom)

^g UNIVERSITY OF BOLOGNA   (Italy)

^h CENTER FOR ZOO AND WILD ANIMAL HEALTH   (Denmark)

ⁱ Rwanda Development Board   (Rwanda)

^j HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^k UNIVERSITY OF CALIFORNIA   (United States)

^l UNIVERSITY OF BARCELONA   (Spain)

^m UNIVERSITY OF CAMBRIDGE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CONSERVATION GENETICS; CONSERVATION MANAGEMENT; ENDANGERED SPECIES; GENETIC DIFFERENTIATION; GENOME; GENOMICS; HOMINID; INBREEDING; MUTATION; POPULATION DECLINE; SURVIVAL;

ANIMAL GENETICS; ARTICLE; CARDIOVASCULAR DISEASE; COPY NUMBER VARIATION; EVOLUTION; GENETIC VARIABILITY; GENOME; GEOGRAPHIC DISTRIBUTION; GORILLA; HETEROZYGOSITY; HISTOCOMPATIBILITY GENE; HUMAN; INBREEDING; MUSCLE HYPERTROPHY; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VOLCANO; Y CHROMOSOME; ADAPTATION; ANIMAL; CLASSIFICATION; COMPARATIVE STUDY; DEMOCRATIC REPUBLIC CONGO; DNA SEQUENCE; ENDANGERED SPECIES; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC SELECTION; GENETIC VARIATION; GENETICS; HOMOZYGOTE; MALE; MUTATION; PHYSIOLOGY; POPULATION DYNAMICS; RWANDA; SPECIES DIFFERENCE; TIME FACTOR;

GORILLA GORILLA BERINGEI; HOMINIDAE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BIOLOGICAL EVOLUTION; DEMOCRATIC REPUBLIC OF THE CONGO; DNA COPY NUMBER VARIATIONS; ENDANGERED SPECIES; FEMALE; GENETIC VARIATION; GENOME; GORILLA GORILLA; HOMOZYGOTE; INBREEDING; LINKAGE DISEQUILIBRIUM; MALE; MUTATION; POPULATION DYNAMICS; RWANDA; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY; TIME FACTORS;

EID: 84927589000     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa3952     Document Type: Article

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