Radiation exposure to comforters and carers during paediatric molecular radiotherapy

Pediatric Blood and Cancer

Volumn 62, Issue 2, 2015, Pages 235-239

  Gains, J E ^a   Walker, C ^a   Sullivan, T M ^a   Waddington, W A ^a   Fersht, N L ^a   Sullivan, K P ^a   Armstrong, E ^a   D'Souza, D P ^a   Aldridge, M D ^a   Bomanji, J B ^a   Gaze, M N ^a  

^a UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Comforters and carers; Molecular radiotherapy; Neuroblastoma; Radiation exposure; Thyroid cancer

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 131; IODINE 131; LUTETIUM 177; SODIUM IODIDE I 131;

ADOLESCENT; ADULT; ARTICLE; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER THERAPY; CAREGIVER; CHILD; EMOTIONAL STRESS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROBLASTOMA; NEUROENDOCRINE TUMOR; PEDIATRIC MOLECULAR RADIOTHERAPY; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RISK REDUCTION; SINGLE DRUG DOSE; THYROID CARCINOMA; UNITED KINGDOM; ENGLAND; INFANT; PRESCHOOL CHILD; PROCEDURES; RADIATION MONITORING; RADIOTHERAPY DOSAGE; STATISTICS AND NUMERICAL DATA; THYROID NEOPLASMS;

ADOLESCENT; CAREGIVERS; CHILD; CHILD, PRESCHOOL; ENGLAND; HUMANS; INFANT; NEUROBLASTOMA; RADIATION EXPOSURE; RADIATION MONITORING; RADIOTHERAPY DOSAGE; THYROID NEOPLASMS;

EID: 84927516174     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.25250     Document Type: Article

References (19)

1. Ionising Radiation Regulations 1999 (SI 1999 No 3232) London, HMSO. - Work with ionizing radiation. Approved code of practice and practical guidance on the Ionising Radiations Regulations 1999, (L121), London HMSO
2. Council Directive 96/29/Euratom of 13th May 1996, laying down basic safety standards for the protection of the health of workers and the general public against the dangers arising form ionising radiation. Off J Eur Commun 1996; 39:1-114.
3. Council Directive 97/43/Euratom of 30th June 1997, on health protection of individuals against the dangers of ionising radiation in relation to medical exposure. Off J Eur Commun 1997; 40.
4. ICRP. 2007a; The 2007 recommendations of the International Commission on Radiological Protection. ICRP Publication 103. Ann ICRP 37.
5. Application of the 2007 recommendations of the ICRP to the UK. Advice from the Health Protection Agency. http://webarchive.nationalarchives.gov.uk/20140714084352/, http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1246519364845 Accessed September 11, 2014.
6. Working party of the radiation protection committee of the British Institute of Radiology, including representatives of the Health and Safety Executive, the Department of Health, the Environment Agency and the National Radiological Protection Board. Patients leaving hospital after administration of radioactive substances. Br J Radiol 1999; 72:121-125.
7. Medical and dental guidance notes. A good practice guide on all aspects of ionizing radiation protection in the clinical environment. Prepared by the Institute of Physics and Engineering in Medicine with the support of National Radiological Protection Board, Health and Safety Executive, The Health Departments and The Environment Agencies. Institute of Physics and Engineering in Medicine 2002.
8. 131mIBG with topotecan as a radiosensitizer in children with metastatic neuroblastoma. Cancer Biother Radiopharm 2005; 20:195-199.
9. Gains JE, Bomanji JB, Fersht NL, et al. 177Lu-DOTATATE molecular radiotherapy for childhood neuroblastoma. J Nucl Med 2011; 52:1041-1047.
10. van der Steen J, Maessen HJ, Hoefnagel CA, et al. Radiation protection during treatment of children with 131I-meta-iodobenzylguanidine. Health Phys 1986; 50:515-522.
11. Tristam M. Radiation Protection. In: Fleming JS, Perkins AC, eds. Targeted radiotherapy: IPEM report 83. London, UK: IPEM; 2001.
12. Markelewicz RJ Jr, Lorenzen WA, Shusterman S, et al. Radiation exposure to family caregivers and nurses of pediatric neuroblastoma patients receiving 131I-metaiodobenzylguanidine (131I-MIBG) therapy. Clin Nucl Med 2013; 38:604-607.
13. Monsieurs M, Thierens H, Dierckx RA, et al. Real life radiation burden to relatives of patients treated with Iodine-131: A study in eight centres in Flanders (Belgium). Eur J Nuc Med 1998; 25:1368-1376.
14. Mathieu I, Caussin J, Smeesters P, et al. Recommended restrictions after 131I therapy: Measured doses in family members. Health Phys 1999; 76:129-136.
15. Thomson WH, Harding LK. Radiation protection issues associated with nuclear medicine out-patients. Nuc Med Comms 1995; 16:879-892.
16. Harbet JC, Wells N. Radiation exposure to the family of radioactive patients. J Nucl Med 1974; 15:887-888.
17. Barrington SF, O'Doherty MJ, Kettle AG, et al. Radiation exposure of the families of outpatients treated with radioiodine (iodine-131) for hyperthyroidism. Eur J Nucl Med 1999; 26:686-692.
18. Barrington SF, Anderson P, Kettle AG, et al. Measurement of the internal dose to families of outpatients treated with 131I for hyperthyroidism. Eur J Nucl Med Mol Imaging. 2008; 35:2097-2104.
19. Singleton M, Griffiths C, Soanes T. Dose constraints for comforters and carers. London, UK: Health and Safety Executive; 2003. Research Report 155.