Low-dose (10-Gy) total skin electron beam therapy for cutaneous t-cell lymphoma: An open clinical study and pooled data analysis

International Journal of Radiation Oncology Biology Physics

Volumn 92, Issue 1, 2015, Pages 138-143

  Kamstrup, Maria R ^a   Gniadecki, Robert ^a   Iversen, Lars ^b   Skov, Lone ^a   Petersen, Peter Meidahl ^a   Loft, Annika ^a   Specht, Lena ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DATA HANDLING; DISEASE CONTROL; ELECTRON BEAMS; INFORMATION ANALYSIS; OPEN DATA; SURVEYS; T-CELLS; TOXICITY;

BENEFICIAL EFFECTS; CLINICAL EFFECTS; COMBINATION TREATMENTS; CUTANEOUS T-CELL LYMPHOMA; METHODS AND MATERIALS; OUTCOME MEASURES; PARTIAL RESPONSE; TOTAL SKIN ELECTRON BEAM THERAPY;

PATIENT TREATMENT;

ALPHA INTERFERON; BEXAROTENE; CHLORAMBUCIL; CHLORMETHINE; ETRETIN; METHOTREXATE; PREDNISOLONE; PSORALEN; STEROID;

ADULT; AGED; ALOPECIA; ANHIDROSIS; ANKLE EDEMA; ARTICLE; BLISTER; CANCER CHEMOTHERAPY; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CUTANEOUS T CELL LYMPHOMA; DATA ANALYSIS; ERYTHEMA; EYE IRRITATION; FEMALE; HUMAN; MALE; MIDDLE AGED; OPEN STUDY; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RADIATION DOSE; SKIN DISCOMFORT; SKIN PAIN; SKIN TOXICITY; TOTAL SKIN ELECTRON THERAPY; TREATMENT DURATION; TREATMENT RESPONSE; VERY ELDERLY; XEROSIS; XEROSTOMIA; ADVERSE EFFECTS; DISEASE FREE SURVIVAL; ELECTRON; LYMPHOMA, T-CELL, CUTANEOUS; MYCOSIS FUNGOIDES; PATHOLOGY; PROCEDURES; RADIATION DOSE FRACTIONATION; RECURRENT DISEASE; RETREATMENT; SEZARY SYNDROME; SKIN NEOPLASMS; THERAPEUTIC USE; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; DISEASE-FREE SURVIVAL; DOSE FRACTIONATION; ELECTRONS; FEMALE; HUMANS; LYMPHOMA, T-CELL, CUTANEOUS; MALE; MIDDLE AGED; MYCOSIS FUNGOIDES; RECURRENCE; RETREATMENT; SEZARY SYNDROME; SKIN NEOPLASMS; TREATMENT OUTCOME;

EID: 84927515102     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2015.01.047     Document Type: Article

References (21)

1. R. Willemze, E.S. Jaffe, and G. Burg WHO-EORTC classification for cutaneous lymphomas Blood 105 2005 3768 3785
2. R. Dummer, C. Assaf, and M. Bagot Maintenance therapy in cutaneous T-cell lymphoma: Who, when, what? Eur J Cancer 43 2007 2321 2329
3. G.W. Jones, R.T. Hoppe, and E. Glatstein Electron beam treatment for cutaneous T-cell lymphoma Hematol Oncol Clin North Am 9 1995 1057 1076
4. G.W. Jones, B.M. Kacinski, and L.D. Wilson Total skin electron radiation in the management of mycosis fungoides: Consensus of the European Organization for Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Project Group J Am Acad Dermatol 47 2002 364 370
5. M. Becker, R.T. Hoppe, and S.J. Knox Multiple courses of high-dose total skin electron beam therapy in the management of mycosis fungoides Int J Radiat Oncol Biol Phys 32 1995 1445 1449
6. L.D. Wilson, P.A. Quiros, and S.A. Kolenik Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma J Am Acad Dermatol 35 1996 69 73
7. C.E. Introcaso, B. Micaily, and S.K. Richardson Total skin electron beam therapy may be associated with improvement of peripheral blood disease in Sezary syndrome J Am Acad Dermatol 58 2008 592 595
8. R.S. Klein, J.D. Dunlop, and S.S. Samimi Improvement in peripheral blood disease burden in patients with Sezary syndrome and leukemic mycosis fungoides after total skin electron beam therapy J Am Acad Dermatol 68 2013 972 977
9. R.T. Hoppe, Z. Fuks, and M.A. Bagshaw The rationale for curative radiotherapy in mycosis fungoides Int J Radiat Oncol Biol Phys 2 1977 843 851
10. C. Harrison, J. Young, and D. Navi Revisiting low-dose total skin electron beam therapy in mycosis fungoides Int J Radiat Oncol Biol Phys 81 2011 651 657
11. M.R. Kamstrup, L. Specht, G.L. Skovgaard, and R. Gniadecki A prospective, open-label study of low-dose total skin electron beam therapy in mycosis fungoides Int J Radiat Oncol Biol Phys 71 2008 1204 1207
12. M.R. Kamstrup, L.M. Lindahl, and R. Gniadecki Low-dose total skin electron beam therapy as a debulking agent for cutaneous T-cell lymphoma: An open-label prospective phase II study Br J Dermatol 166 2012 399 404
13. E. Olsen, E. Vonderheid, and N. Pimpinelli Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: A proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC) Blood 110 2007 1713 1722
14. R.S. Cox, R.J. Heck, and P. Fessenden Development of total-skin electron therapy at two energies Int J Radiat Oncol Biol Phys 18 1990 659 669
15. L.M. Lindahl, M.R. Kamstrup, and P.M. Petersen Total skin electron beam therapy for cutaneous T-cell lymphoma: A nationwide cohort study from Denmark Acta Oncol 50 2011 1199 1205
16. S. Lloyd, Z. Chen, and F.M. Foss Acute toxicity and risk of infection during total skin electron beam therapy for mycosis fungoides J Am Acad Dermatol 69 2013 537 543
17. G.W. Jones, A. Tadros, and D.I. Hodson Prognosis with newly diagnosed mycosis fungoides after total skin electron radiation of 30 or 55 Gy Int J Radiat Oncol Biol Phys 28 1994 839 845
18. S.F. Barringtoon, N.G. Mikhaeel, and L. Kostakoglu Role of imaging in the staging and response assessment of lymphoma: Consensus of the International Conference on Malignant Lymphomas Imaging Working Group J Clin Oncol 32 2014 3048 3058
19. D. Navi, N. Riaz, and Y.S. Levin The Stanford University experience with conventional-dose, total skin electron-beam therapy in the treatment of generalized patch or plaque (T2) and tumor (T3) mycosis fungoides Arch Dermatol 147 2011 561 567
20. Hoppe RT, Harrison C, Tavallaee M, et al. Low-dose total skin electron beam therapy as an effective modality to reduce disease burden in patients with mycosis fungoides: Results of a pooled analysis from 3 phase-II clinical trials. J Am Acad Dermatol 2015 72:286-292.
21. J.B. Yu, A.M. Khan, and G.W. Jones Patient perspectives regarding the value of total skin electron beam therapy for cutaneous T-cell lymphoma/mycosis fungoides: A pilot study Am J Clin Oncol 32 2009 142 144