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Volumn 30, Issue 3, 2015, Pages 167-174

A pilot randomized placebo-controlled trial of adjunctive aripiprazole for chronic PTSD in US military Veterans resistant to antidepressant treatment

Author keywords

Antipsychotic; Anxiety; Aripiprazole; Clinical trial; Controlled; Depression; Post traumatic stress disorder; Psychosis; Randomized; Veterans

Indexed keywords

ARIPIPRAZOLE; PLACEBO; ANTIDEPRESSANT AGENT; NEUROLEPTIC AGENT;

EID: 84927178285     PISSN: 02681315     EISSN: 14735857     Source Type: Journal    
DOI: 10.1097/YIC.0000000000000061     Document Type: Article
Times cited : (29)

References (35)
  • 1
    • 31744447100 scopus 로고    scopus 로고
    • Quetiapine as an adjunctive treatment for post-traumatic stress disorder: An 8-week openlabel study
    • Ahearn EP, Mussey M, Johnson C, Krohn A, Krahn D (2006). Quetiapine as an adjunctive treatment for post-traumatic stress disorder: an 8-week openlabel study. Int Clin Psychopharmacol 21:29-33.
    • (2006) Int Clin Psychopharmacol , vol.21 , pp. 29-33
    • Ahearn, E.P.1    Mussey, M.2    Johnson, C.3    Krohn, A.4    Krahn, D.5
  • 2
    • 14644423248 scopus 로고    scopus 로고
    • Adjunctive risperidone in the treatment of chronic combat-related posttraumatic stress disorder
    • Bartzokis G, Lu PH, Turner J, Mintz J, Saunders CS (2005). Adjunctive risperidone in the treatment of chronic combat-related posttraumatic stress disorder. Biol Psychiatry 57:474-479.
    • (2005) Biol Psychiatry , vol.57 , pp. 474-479
    • Bartzokis, G.1    Lu, P.H.2    Turner, J.3    Mintz, J.4    Saunders, C.S.5
  • 4
    • 34347335477 scopus 로고    scopus 로고
    • The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: A multicenter, randomized, double-blind, placebo-controlled study
    • Berman RM, Marcus RN, Swanink R, McQuade RD, Carson WH, Corey-Lisle PK, Khan A (2007). The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a multicenter, randomized, double-blind, placebo-controlled study. J Clin Psychiatry 68:843-853.
    • (2007) J Clin Psychiatry , vol.68 , pp. 843-853
    • Berman, R.M.1    Marcus, R.N.2    Swanink, R.3    McQuade, R.D.4    Carson, W.H.5    Corey-Lisle, P.K.6    Khan, A.7
  • 5
    • 66849141289 scopus 로고    scopus 로고
    • Aripiprazole augmentation in major depressive disorder: A double-blind, placebo-controlled study in patients with inadequate response to anti-depressants
    • Berman RM, Fava M, Thase ME, Trivedi MH, Swanink R, McQuade RD, et al. (2009). Aripiprazole augmentation in major depressive disorder: a double-blind, placebo-controlled study in patients with inadequate response to anti-depressants. CNS Spectr 14:197-206.
    • (2009) CNS Spectr , vol.14 , pp. 197-206
    • Berman, R.M.1    Fava, M.2    Thase, M.E.3    Trivedi, M.H.4    Swanink, R.5    McQuade, R.D.6
  • 7
    • 0034639954 scopus 로고    scopus 로고
    • Efficacy and safety of sertraline treatment of posttraumatic stress disorder: A randomized controlled trial
    • Brady K, Pearlstein T, Asnis GM, Baker D, Rothbaum B, Sikes CR, Farfel GM (2000). Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial. JAMA 283:1837-1844.
    • (2000) JAMA , vol.283 , pp. 1837-1844
    • Brady, K.1    Pearlstein, T.2    Asnis, G.M.3    Baker, D.4    Rothbaum, B.5    Sikes, C.R.6    Farfel, G.M.7
  • 9
    • 84864117524 scopus 로고    scopus 로고
    • Olanzapine monotherapy in posttraumatic stress disorder: Efficacy in a randomized, double-blind, placebo-controlled study
    • Carey P, Suliman S, Ganesan K, Seedat S, Stein DJ (2012). Olanzapine monotherapy in posttraumatic stress disorder: efficacy in a randomized, double-blind, placebo-controlled study. Hum Psychopharmacol 27:386-391.
    • (2012) Hum Psychopharmacol , vol.27 , pp. 386-391
    • Carey, P.1    Suliman, S.2    Ganesan, K.3    Seedat, S.4    Stein, D.J.5
  • 10
    • 0141731320 scopus 로고    scopus 로고
    • Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC)
    • Connor KM, Davidson JR (2003). Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC). Depress Anxiety 18:76-82.
    • (2003) Depress Anxiety , vol.18 , pp. 76-82
    • Connor, K.M.1    Davidson, J.R.2
  • 11
    • 84894317267 scopus 로고    scopus 로고
    • Antidepressant response to aripiprazole augmentation associated with enhanced FDOPA utilization in striatum: A preliminary PET study
    • Conway CR, Chibnall JT, Cumming P, Mintun MA, Gebara MA, Perantie DC, et al. (2014). Antidepressant response to aripiprazole augmentation associated with enhanced FDOPA utilization in striatum: a preliminary PET study. Psychiatry Res 221:231-239.
    • (2014) Psychiatry Res , vol.221 , pp. 231-239
    • Conway, C.R.1    Chibnall, J.T.2    Cumming, P.3    Mintun, M.A.4    Gebara, M.A.5    Perantie, D.C.6
  • 13
    • 0037308244 scopus 로고    scopus 로고
    • Quetiapine treatment in patients with posttraumatic stress disorder: An open trial of adjunctive therapy
    • Hamner MB, Deitsch SE, Brodrick PS, Ulmer HG, Lorberbaum JP (2003). Quetiapine treatment in patients with posttraumatic stress disorder: an open trial of adjunctive therapy. J Clin Psychopharmacol 23:15-20.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 15-20
    • Hamner, M.B.1    Deitsch, S.E.2    Brodrick, P.S.3    Ulmer, H.G.4    Lorberbaum, J.P.5
  • 14
    • 61649113529 scopus 로고    scopus 로고
    • The association of posttraumatic stress disorder and metabolic syndrome: A study of increased health risk in veterans
    • Heppner PS, Crawford EF, Haji UA, Afari N, Hauger RL, Dashevsky BA, et al. (2009). The association of posttraumatic stress disorder and metabolic syndrome: a study of increased health risk in veterans. BMC Med 7:1.
    • (2009) BMC Med , vol.7 , pp. 1
    • Heppner, P.S.1    Crawford, E.F.2    Haji, U.A.3    Afari, N.4    Hauger, R.L.5    Dashevsky, B.A.6
  • 15
    • 0036738786 scopus 로고    scopus 로고
    • Efficacy and safety of aripiprazole and haloperidol versus placebo in patients with schizophrenia and schizoaffective disorder
    • Kane JM, Carson WH, Saha AR, McQuade RD, Ingenito GG, Zimbroff DL, Ali MW (2002). Efficacy and safety of aripiprazole and haloperidol versus placebo in patients with schizophrenia and schizoaffective disorder. J Clin Psychiatry 63:763-771.
    • (2002) J Clin Psychiatry , vol.63 , pp. 763-771
    • Kane, J.M.1    Carson, W.H.2    Saha, A.R.3    McQuade, R.D.4    Ingenito, G.G.5    Zimbroff, D.L.6    Ali, M.W.7
  • 16
    • 0038585981 scopus 로고    scopus 로고
    • A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole in patients with acute bipolar mania
    • Keck PE Jr, Marcus R, Tourkodimitris S, Ali M, Liebeskind A, Saha A, Ingenito G. Aripiprazole Study Group (2003). A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole in patients with acute bipolar mania. Am J Psychiatry 160:1651-1658.
    • (2003) Am J Psychiatry , vol.160 , pp. 1651-1658
    • Keck, P.E.1    Marcus, R.2    Tourkodimitris, S.3    Ali, M.4    Liebeskind, A.5    Saha, A.6    Ingenito, G.7
  • 18
    • 33847049883 scopus 로고    scopus 로고
    • Quetiapine treatment in an open trial in combat-related post-traumatic stress disorder with psychotic features
    • Kozaric-Kovacic D, Pivac N (2007). Quetiapine treatment in an open trial in combat-related post-traumatic stress disorder with psychotic features. Int J Neuropsychopharmacol 10:253-261.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 253-261
    • Kozaric-Kovacic, D.1    Pivac, N.2
  • 19
    • 22744451818 scopus 로고    scopus 로고
    • Risperidone in psychotic combat-related posttraumatic stress disorder: An open trial
    • Kozarić-Kovacić D, Pivac N, Mück-Seler D, Rothbaum BO (2005). Risperidone in psychotic combat-related posttraumatic stress disorder: an open trial. J Clin Psychiatry 66:922-927.
    • (2005) J Clin Psychiatry , vol.66 , pp. 922-927
    • Kozarić-Kovacić, D.1    Pivac, N.2    Mück-Seler, D.3    Rothbaum, B.O.4
  • 20
    • 79961040968 scopus 로고    scopus 로고
    • Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: A randomized trial
    • Krystal JH, Rosenheck RA, Cramer JA, Vessicchio JC, Jones KM, Vertrees JE, et al. Veterans Affairs Cooperative Study No. 504 Group (2011). Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: a randomized trial. JAMA 306:493-502.
    • (2011) JAMA , vol.306 , pp. 493-502
    • Krystal, J.H.1    Rosenheck, R.A.2    Cramer, J.A.3    Vessicchio, J.C.4    Jones, K.M.5    Vertrees, J.E.6
  • 21
    • 40949089056 scopus 로고    scopus 로고
    • The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: A second multicenter, randomized, double-blind, placebo-controlled study
    • Marcus RN, McQuade RD, Carson WH, Hennicken D, Fava M, Simon JS, et al. (2008). The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a second multicenter, randomized, double-blind, placebo-controlled study. J Clin Psychopharmacol 28:156-165.
    • (2008) J Clin Psychopharmacol , vol.28 , pp. 156-165
    • Marcus, R.N.1    McQuade, R.D.2    Carson, W.H.3    Hennicken, D.4    Fava, M.5    Simon, J.S.6
  • 22
    • 0035189776 scopus 로고    scopus 로고
    • Efficacy and safety of paroxetine treatment for chronic PTSD: A fixed-dose, placebocontrolled study
    • Marshall RD, Beebe KL, Oldham M, Zaninelli R (2001). Efficacy and safety of paroxetine treatment for chronic PTSD: a fixed-dose, placebocontrolled study. Am J Psychiatry 158:1982-1988.
    • (2001) Am J Psychiatry , vol.158 , pp. 1982-1988
    • Marshall, R.D.1    Beebe, K.L.2    Oldham, M.3    Zaninelli, R.4
  • 23
    • 58549112958 scopus 로고    scopus 로고
    • Aripiprazole in the treatment of posttraumatic stress disorder: An open-label trial
    • Mello MF, Costa MC, Schoedl AF, Fiks JP (2008). Aripiprazole in the treatment of posttraumatic stress disorder: an open-label trial. Rev Bras Psiquiatr 30:358-361.
    • (2008) Rev Bras Psiquiatr , vol.30 , pp. 358-361
    • Mello, M.F.1    Costa, M.C.2    Schoedl, A.F.3    Fiks, J.P.4
  • 24
    • 0037380689 scopus 로고    scopus 로고
    • Low-dose risperidone as adjunctive therapy for irritable aggression in posttraumatic stress disorder
    • Monnelly EP, Ciraulo DA, Knapp C, Keane T (2003). Low-dose risperidone as adjunctive therapy for irritable aggression in posttraumatic stress disorder. J Clin Psychopharmacol 23:193-196.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 193-196
    • Monnelly, E.P.1    Ciraulo, D.A.2    Knapp, C.3    Keane, T.4
  • 25
    • 33746686967 scopus 로고    scopus 로고
    • Risperidone monotherapy for post-traumatic stress disorder related to sexual assault and domestic abuse in women
    • Padala PR, Madison J, Monnahan M, Marcil W, Price P, Ramaswamy S, et al. (2006). Risperidone monotherapy for post-traumatic stress disorder related to sexual assault and domestic abuse in women. Int Clin Psychopharmacol 21:275-280.
    • (2006) Int Clin Psychopharmacol , vol.21 , pp. 275-280
    • Padala, P.R.1    Madison, J.2    Monnahan, M.3    Marcil, W.4    Price, P.5    Ramaswamy, S.6
  • 27
    • 33745246855 scopus 로고    scopus 로고
    • Pharmacotherapy of treatment-resistant combat-related posttraumatic stress disorder with psychotic features
    • Pivac N, Kozarić-Kovacić D (2006). Pharmacotherapy of treatment-resistant combat-related posttraumatic stress disorder with psychotic features. Croat Med J 47:440-451.
    • (2006) Croat Med J , vol.47 , pp. 440-451
    • Pivac, N.1    Kozarić-Kovacić, D.2
  • 28
    • 5444225306 scopus 로고    scopus 로고
    • Olanzapine versus fluphenazine in an open trial in patients with psychotic combat-related post-traumatic stress disorder
    • Pivac N, Kozaric-Kovacic D, Muck-Seler D (2004). Olanzapine versus fluphenazine in an open trial in patients with psychotic combat-related post-traumatic stress disorder. Psychopharmacology (Berl) 175:451-456.
    • (2004) Psychopharmacology (Berl) , vol.175 , pp. 451-456
    • Pivac, N.1    Kozaric-Kovacic, D.2    Muck-Seler, D.3
  • 29
    • 13744255491 scopus 로고    scopus 로고
    • A preliminary study of risperidone in the treatment of posttraumatic stress disorder related to childhood abuse in women
    • Reich DB, Winternitz S, Hennen J, Watts T, Stanculescu C (2004). A preliminary study of risperidone in the treatment of posttraumatic stress disorder related to childhood abuse in women. J Clin Psychiatry 65:1601-1606.
    • (2004) J Clin Psychiatry , vol.65 , pp. 1601-1606
    • Reich, D.B.1    Winternitz, S.2    Hennen, J.3    Watts, T.4    Stanculescu, C.5
  • 31
    • 44849108132 scopus 로고    scopus 로고
    • Placebo-controlled trial of risperidone augmentation for selective serotonin reuptake inhibitor-resistant civilian posttraumatic stress disorder
    • Rothbaum BO, Killeen TK, Davidson JR, Brady KT, Connor KM, Heekin MH (2008). Placebo-controlled trial of risperidone augmentation for selective serotonin reuptake inhibitor-resistant civilian posttraumatic stress disorder. J Clin Psychiatry 69:520-525.
    • (2008) J Clin Psychiatry , vol.69 , pp. 520-525
    • Rothbaum, B.O.1    Killeen, T.K.2    Davidson, J.R.3    Brady, K.T.4    Connor, K.M.5    Heekin, M.H.6
  • 32
    • 27544485778 scopus 로고    scopus 로고
    • Aripiprazole augmentation of antidepressants for the treatment of partially responding and nonresponding patients with major depressive disorder
    • Simon JS, Nemeroff CB (2005). Aripiprazole augmentation of antidepressants for the treatment of partially responding and nonresponding patients with major depressive disorder. J Clin Psychiatry 66 :1216-1220.
    • (2005) J Clin Psychiatry , vol.66 , pp. 1216-1220
    • Simon, J.S.1    Nemeroff, C.B.2
  • 33
    • 0036789143 scopus 로고    scopus 로고
    • Adjunctive olanzapine for SSRI-resistant combat-related PTSD: A double-blind, placebo-controlled study
    • Stein MB, Kline NA, Matloff JL (2002). Adjunctive olanzapine for SSRI-resistant combat-related PTSD: a double-blind, placebo-controlled study. Am J Psychiatry 159:1777-1779.
    • (2002) Am J Psychiatry , vol.159 , pp. 1777-1779
    • Stein, M.B.1    Kline, N.A.2    Matloff, J.L.3
  • 34
    • 34548561615 scopus 로고    scopus 로고
    • Prospective study to evaluate the efficacy of aripiprazole as a monotherapy in patients with severe chronic posttraumatic stress disorder: An open trial
    • Villarreal G, Calais LA, Cañive JM, Lundy SL, Pickard J, Toney G (2007). Prospective study to evaluate the efficacy of aripiprazole as a monotherapy in patients with severe chronic posttraumatic stress disorder: an open trial. Psychopharmacol Bull 40:6-18.
    • (2007) Psychopharmacol Bull , vol.40 , pp. 6-18
    • Villarreal, G.1    Calais, L.A.2    Cañive, J.M.3    Lundy, S.L.4    Pickard, J.5    Toney, G.6
  • 35
    • 84862116033 scopus 로고    scopus 로고
    • An open-label pilot study of aripiprazole for male and female veterans with chronic post-traumatic stress disorder who respond suboptimally to anti-depressants
    • Youssef NA, Marx CE, Bradford DW, Zinn S, Hertzberg MA, Kilts JD, et al. (2012). An open-label pilot study of aripiprazole for male and female veterans with chronic post-traumatic stress disorder who respond suboptimally to anti-depressants. Int Clin Psychopharmacol 27:191-196.
    • (2012) Int Clin Psychopharmacol , vol.27 , pp. 191-196
    • Youssef, N.A.1    Marx, C.E.2    Bradford, D.W.3    Zinn, S.4    Hertzberg, M.A.5    Kilts, J.D.6


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