-
1
-
-
77954580523
-
Multiplicity of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC) patients treated with tyrosine kinase inhibitors
-
Benesova L, Minarik M, Jancarikova D, Belsanova B, Pesek M (2010) Multiplicity of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC) patients treated with tyrosine kinase inhibitors. Anticancer Res 30(5): 1667-1671.
-
(2010)
Anticancer Res
, vol.30
, Issue.5
, pp. 1667-1671
-
-
Benesova, L.1
Minarik, M.2
Jancarikova, D.3
Belsanova, B.4
Pesek, M.5
-
2
-
-
84885029292
-
Frequency of EGFR mutations in 907 lung adenocarcioma patients of Indian ethnicity
-
Chougule A, Prabhash K, Noronha V, Joshi A, Thavamani A, Chandrani P, Upadhyay P, Utture S, Desai S, Jambhekar N, Dutt A (2013) Frequency of EGFR mutations in 907 lung adenocarcioma patients of Indian ethnicity. PLoS One 8(10): e76164.
-
(2013)
PLoS One
, vol.8
, Issue.10
-
-
Chougule, A.1
Prabhash, K.2
Noronha, V.3
Joshi, A.4
Thavamani, A.5
Chandrani, P.6
Upadhyay, P.7
Utture, S.8
Desai, S.9
Jambhekar, N.10
Dutt, A.11
-
3
-
-
79960702788
-
Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS)
-
Fukuoka M, Wu YL, Thongprasert S, Sunpaweravong P, Leong SS, Sriuranpong V, Chao TY, Nakagawa K, Chu DT, Saijo N, Duffield EL, Rukazenkov Y, Speake G, Jiang H, Armour AA, To KF, Yang JC, Mok TS (2011) Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS). J Clin Oncol 29(21): 2866-2874.
-
(2011)
J Clin Oncol
, vol.29
, Issue.21
, pp. 2866-2874
-
-
Fukuoka, M.1
Wu, Y.L.2
Thongprasert, S.3
Sunpaweravong, P.4
Leong, S.S.5
Sriuranpong, V.6
Chao, T.Y.7
Nakagawa, K.8
Chu, D.T.9
Saijo, N.10
Duffield, E.L.11
Rukazenkov, Y.12
Speake, G.13
Jiang, H.14
Armour, A.A.15
To, K.F.16
Yang, J.C.17
Mok, T.S.18
-
4
-
-
29244463359
-
Mutational analysis of K-RAS and EGFR implicates KRAS as a resistance marker in the Southwest Oncology Group (SWOG) trial S0126 of bronchioalveolar carcinoma (BAC) patients (pts) treated with gefitinib
-
abstr 7008
-
Gumerlock PH, Holland WS, Chen H, Franklin WA, Hirsch FR, Mack PC, Davies AM, McCoy J, West HJ, Gandara DR (2005) Mutational analysis of K-RAS and EGFR implicates KRAS as a resistance marker in the Southwest Oncology Group (SWOG) trial S0126 of bronchioalveolar carcinoma (BAC) patients (pts) treated with gefitinib. Proc Am Soc Clin Oncol 23(Suppl 623s): abstr 7008.
-
(2005)
Proc Am Soc Clin Oncol
, vol.23
-
-
Gumerlock, P.H.1
Holland, W.S.2
Chen, H.3
Franklin, W.A.4
Hirsch, F.R.5
Mack, P.C.6
Davies, A.M.7
McCoy, J.8
West, H.J.9
Gandara, D.R.10
-
5
-
-
84863116014
-
Effect of KRAS oncogene substitutions on protein behavior: Implications for signaling and clinical outcome
-
Ihle NT, Byers LA, Kim ES, Saintigny P, Lee JJ, Blumenschein GR, Tsao A, Liu S, Larsen JE, Wang J, Diao L, Coombes KR, Chen L, Zhang S, Abdelmelek MF, Tang X, Papadimitrakopoulou V, Minna JD, Lippman SM, Hong WK, Herbst RS, Wistuba II, Heymach JV, Powis G (2012) Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. J Natl Cancer Inst 104(3): 228-239.
-
(2012)
J Natl Cancer Inst
, vol.104
, Issue.3
, pp. 228-239
-
-
Ihle, N.T.1
Byers, L.A.2
Kim, E.S.3
Saintigny, P.4
Lee, J.J.5
Blumenschein, G.R.6
Tsao, A.7
Liu, S.8
Larsen, J.E.9
Wang, J.10
Diao, L.11
Coombes, K.R.12
Chen, L.13
Zhang, S.14
Abdelmelek, M.F.15
Tang, X.16
Papadimitrakopoulou, V.17
Minna, J.D.18
Lippman, S.M.19
Hong, W.K.20
Herbst, R.S.21
Wistuba, I.I.22
Heymach, J.V.23
Powis, G.24
more..
-
6
-
-
10844231985
-
Mutations of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications
-
Kosaka T, Yatabe Y, Endoh H, Kuwano H, Takahashi T, Mitsudomi T (2004) Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 64(24): 8919-8923.
-
(2004)
Cancer Res
, vol.64
, Issue.24
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
Kuwano, H.4
Takahashi, T.5
Mitsudomi, T.6
-
7
-
-
84901590009
-
Coexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: A comprehensive mutation profiling from 5125 Chinese cohorts
-
Li S, Li L, Zhu Y, Huang C, Qin Y, Liu H, Ren-Heidenreich L, Shi B, Ren H, Chu X, Kang J, Wang W, Xu J, Tang K, Yang H, Zheng Y, He J, Yu G, Liang N (2014) Coexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: a comprehensive mutation profiling from 5125 Chinese cohorts. Br J Cancer 110(11): 2812-2820.
-
(2014)
Br J Cancer
, vol.110
, Issue.11
, pp. 2812-2820
-
-
Li, S.1
Li, L.2
Zhu, Y.3
Huang, C.4
Qin, Y.5
Liu, H.6
Ren-Heidenreich, L.7
Shi, B.8
Ren, H.9
Chu, X.10
Kang, J.11
Wang, W.12
Xu, J.13
Tang, K.14
Yang, H.15
Zheng, Y.16
He, J.17
Yu, G.18
Liang, N.19
-
8
-
-
33646228635
-
KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
-
Lievre A, Bachet JB, Le Corre D, Boige V, Landi B, Emile JF, Cote JF, Tomasic G, Penna C, Ducreux M, Rougier P, Penault-Llorca F, Laurent-Puig P (2006) KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res 66(8): 3992-3995.
-
(2006)
Cancer Res
, vol.66
, Issue.8
, pp. 3992-3995
-
-
Lievre, A.1
Bachet, J.B.2
Le Corre, D.3
Boige, V.4
Landi, B.5
Emile, J.F.6
Cote, J.F.7
Tomasic, G.8
Penna, C.9
Ducreux, M.10
Rougier, P.11
Penault-Llorca, F.12
Laurent-Puig, P.13
-
9
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, Settleman J, Haber DA (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350(21): 2129-2139.
-
(2004)
N Engl J Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
10
-
-
77955096407
-
KRAS mutations and resistance to EGFR-TKIs treatment in patients with non-small cell lung cancer: A meta-analysis of 22 studies
-
Mao C, Qiu LX, Liao RY, Du FB, Ding H, Yang WC, Li J, Chen Q (2010) KRAS mutations and resistance to EGFR-TKIs treatment in patients with non-small cell lung cancer: a meta-analysis of 22 studies. Lung Cancer 69(3): 272-278.
-
(2010)
Lung Cancer
, vol.69
, Issue.3
, pp. 272-278
-
-
Mao, C.1
Qiu, L.X.2
Liao, R.Y.3
Du, F.B.4
Ding, H.5
Yang, W.C.6
Li, J.7
Chen, Q.8
-
11
-
-
20244388126
-
Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
-
Mitsudomi T, Kosaka T, Endoh H, Horio Y, Hida T, Mori S, Li J, Chen Q (2005) Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 23(11): 2513-2520.
-
(2005)
J Clin Oncol
, vol.23
, Issue.11
, pp. 2513-2520
-
-
Mitsudomi, T.1
Kosaka, T.2
Endoh, H.3
Horio, Y.4
Hida, T.5
Mori, S.6
Li, J.7
Chen, Q.8
-
12
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, Yang CH, Chu DT, Saijo N, Sunpaweravong P, Han B, Margono B, Ichinose Y, Nishiwaki Y, Ohe Y, Yang JJ, Chewaskulyong B, Jiang H, Duffield EL, Watkins CL, Armour AA, Fukuoka M (2009) Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 361(10): 947-957.
-
(2009)
N Engl J Med
, vol.361
, Issue.10
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
Yang, C.H.4
Chu, D.T.5
Saijo, N.6
Sunpaweravong, P.7
Han, B.8
Margono, B.9
Ichinose, Y.10
Nishiwaki, Y.11
Ohe, Y.12
Yang, J.J.13
Chewaskulyong, B.14
Jiang, H.15
Duffield, E.L.16
Watkins, C.L.17
Armour, A.A.18
Fukuoka, M.19
-
13
-
-
84876447147
-
EGFR mutations in Indian lung cancer patients: Clinical correlation and outcome to EGFR targeted therapy
-
Noronha V, Prabhash K, Thavamani A, Chougule A, Purandare N, Joshi A, Sharma R, Desai S, Jambekar N, Dutt A, Mulherkar R (2013) EGFR mutations in Indian lung cancer patients: clinical correlation and outcome to EGFR targeted therapy. PLoS One 8(4): e61561.
-
(2013)
PLoS One
, vol.8
, Issue.4
-
-
Noronha, V.1
Prabhash, K.2
Thavamani, A.3
Chougule, A.4
Purandare, N.5
Joshi, A.6
Sharma, R.7
Desai, S.8
Jambekar, N.9
Dutt, A.10
Mulherkar, R.11
-
14
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, Gabriel S, Herman P, Kaye FJ, Lindeman N, Boggon TJ, Naoki K, Sasaki H, Fujii Y, Eck MJ, Sellers WR, Johnson BE, Meyerson M (2004) EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304(5676): 1497-1500.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
15
-
-
15744372810
-
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
-
Pao W, Wang TY, Riely GJ, Miller VA, Pan Q, Ladanyi M, Zakowski MF, Heelan RT, Kris MG, Varmus HE (2005) KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2(1): e17.
-
(2005)
PLoS Med
, vol.2
, Issue.1
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
Miller, V.A.4
Pan, Q.5
Ladanyi, M.6
Zakowski, M.F.7
Heelan, R.T.8
Kris, M.G.9
Varmus, H.E.10
-
16
-
-
78149249388
-
Personalized medicine in non-small-cell lung cancer: Is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
-
Roberts PJ, Stinchcombe TE, Der CJ, Socinski MA (2010) Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy? J Clin Oncol 28(31): 4769-4777.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4769-4777
-
-
Roberts, P.J.1
Stinchcombe, T.E.2
Der, C.J.3
Socinski, M.A.4
-
17
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H, Lin L, Takahashi T, Nomura M, Suzuki M, Wistuba II, Fong KM, Lee H, Toyooka S, Shimizu N, Fujisawa T, Feng Z, Roth JA, Herz J, Minna JD, Gazdar AF (2005) Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 97(5): 339-346.
-
(2005)
J Natl Cancer Inst
, vol.97
, Issue.5
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
Nomura, M.4
Suzuki, M.5
Wistuba, I.I.6
Fong, K.M.7
Lee, H.8
Toyooka, S.9
Shimizu, N.10
Fujisawa, T.11
Feng, Z.12
Roth, J.A.13
Herz, J.14
Minna, J.D.15
Gazdar, A.F.16
-
18
-
-
33645052711
-
Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features
-
Tam IY, Chung LP, Suen WS, Wang E, Wong MC, Ho KK, Lam WK, Chiu SW, Girard L, Minna JD, Gazdar AF, Wong MP (2006) Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features. Clin Cancer Res 12(5): 1647-1653.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.5
, pp. 1647-1653
-
-
Tam, I.Y.1
Chung, L.P.2
Suen, W.S.3
Wang, E.4
Wong, M.C.5
Ho, K.K.6
Lam, W.K.7
Chiu, S.W.8
Girard, L.9
Minna, J.D.10
Gazdar, A.F.11
Wong, M.P.12
-
19
-
-
52049090365
-
Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
-
Zhu CQ, da Cunha Santos G, Ding K, Sakurada A, Cutz JC, Liu N, Zhang T, Marrano P, Whitehead M, Squire JA, Kamel-Reid S, Seymour L, Shepherd FA, Tsao MS (2008) Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 26(26): 4268-4275.
-
(2008)
J Clin Oncol
, vol.26
, Issue.26
, pp. 4268-4275
-
-
Zhu, C.Q.1
Da Cunha Santos, G.2
Ding, K.3
Sakurada, A.4
Cutz, J.C.5
Liu, N.6
Zhang, T.7
Marrano, P.8
Whitehead, M.9
Squire, J.A.10
Kamel-Reid, S.11
Seymour, L.12
Shepherd, F.A.13
Tsao, M.S.14
|