Cell cycle status of CD34 + hemopoietic stem cells determines lentiviral integration in actively transcribed and development-related genes

Molecular Therapy

Volumn 23, Issue 4, 2015, Pages 683-696

  Papanikolaou, Eleni ^a,b   Paruzynski, Anna ^c   Kasampalidis, Ioannis ^a   Deichmann, Annette ^c   Stamateris, Evangelos ^b   Schmidt, Manfred ^c   Von Kalle, Christof ^c   Anagnou, Nicholas P ^a,b  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; CD34 ANTIGEN; LENTIVIRUS VECTOR; NOCODAZOLE; PACLITAXEL; THYMINE; TRANSCRIPTOME;

AMPLICON; ARTICLE; BIOINFORMATICS; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE STATUS; CHROMOSOMAL DISTRIBUTION; CHROMOSOMAL PARAMETERS; COMPARATIVE STUDY; COMPUTER MODEL; CONTROLLED STUDY; CPG ISLAND; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; HUMAN GENOME; INSERTIONAL MUTAGENESIS; INTEGRATION SITE; LINEAR AMPLIFICATION MEDIATED POLYMERASE CHAIN REACTION; M PHASE CELL CYCLE CHECKPOINT; MICROARRAY ANALYSIS; MITOSIS; MOLECULAR DYNAMICS; MUTAGENESIS; POLYMERASE CHAIN REACTION; RNA TRANSLATION; SEQUENCE ALIGNMENT; VIRAL GENE DELIVERY SYSTEM; VIRAL PHENOMENA AND FUNCTIONS; VIRUS DNA CELL DNA INTERACTION; VIRUS GENOME; CYTOLOGY; GENE VECTOR; GENETICS; IMMUNOLOGY; LENTIVIRINAE;

ANTIGENS, CD34; CELL CYCLE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC VECTORS; HEMATOPOIETIC STEM CELLS; HUMANS; LENTIVIRUS; TRANSCRIPTION, GENETIC; VIRUS INTEGRATION;

EID: 84927098682     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2014.246     Document Type: Article

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