-
1
-
-
84870441080
-
Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein
-
Belda O, Targett-Adams P. Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein. Virus Res 2012; 170:1-14.
-
(2012)
Virus Res
, vol.170
, pp. 1-14
-
-
Belda, O.1
Targett-Adams, P.2
-
2
-
-
84885949784
-
Antiviral activity and resistance of HCV NS5A replication complex inhibitors
-
Gao M. Antiviral activity and resistance of HCV NS5A replication complex inhibitors. Curr Opin Virol 2013; 3:1-7.
-
(2013)
Curr Opin Virol
, vol.3
, pp. 1-7
-
-
Gao, M.1
-
3
-
-
82455192239
-
Genotypic and phenotypic analysis of variants resistant to hepatitis C virus non-structural protein 5A replication complex inhibitor BMS-790052 in humans: In vitro and in vivo correlations
-
Fridell RA, Wang C, Sun JH, et al. Genotypic and phenotypic analysis of variants resistant to hepatitis C virus non-structural protein 5A replication complex inhibitor BMS-790052 in humans: in vitro and in vivo correlations. Hepatology 2011; 54:1924-1935.
-
(2011)
Hepatology
, vol.54
, pp. 1924-1935
-
-
Fridell, R.A.1
Wang, C.2
Sun, J.H.3
-
4
-
-
84862684876
-
A phase 1, randomized placebo-controlled, 3-day, dose-ranging study of GS-5885, an NS5A inhibitor, in patients with genotype 1 hepatitis C
-
Lawitz EJ, Gruener D, Hill JM, et al. A Phase 1, randomized placebo-controlled, 3-day, dose-ranging study of GS-5885, an NS5A inhibitor, in patients with genotype 1 hepatitis C. J Hepatol 2012; 57:24-31.
-
(2012)
J Hepatol
, vol.57
, pp. 24-31
-
-
Lawitz, E.J.1
Gruener, D.2
Hill, J.M.3
-
5
-
-
77952035218
-
Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
-
Gao M, Nettles R, Belema M, et al. Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect. Nature 2010; 465:96-100.
-
(2010)
Nature
, vol.465
, pp. 96-100
-
-
Gao, M.1
Nettles, R.2
Belema, M.3
-
6
-
-
77956116880
-
Resistance analysis of the hepatitis C virus NS5A inhibitor BMS-790052 in an in vitro replicon system
-
Fridell RA, Qiu D, Wang C, Valera L, Gao M. Resistance analysis of the hepatitis C virus NS5A inhibitor BMS-790052 in an in vitro replicon system. Antimicrob Agents Chemother 2010; 54:3641-3650.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3641-3650
-
-
Fridell, R.A.1
Qiu, D.2
Wang, C.3
Valera, L.4
Gao, M.5
-
7
-
-
84856159009
-
Preliminary study of two antiviral agents for hepatitis C genotype 1
-
Lok AS, Gardiner D F, Lawitz E, et al. Preliminary study of two antiviral agents for hepatitis C genotype 1. N Engl J Med 2012; 366:216-224.
-
(2012)
N Engl J Med
, vol.366
, pp. 216-224
-
-
Lok, A.S.1
Gardiner, D.F.2
Lawitz, E.3
-
8
-
-
84875660709
-
Hepatitis C virus subtyping based on sequencing of the C/E1 and NS5B genomic regions in comparison to a commercially available line probe assay
-
Avá AP, Água-Doce I, Andrade A, Pádua E. Hepatitis C virus subtyping based on sequencing of the C/E1 and NS5B genomic regions in comparison to a commercially available line probe assay. J Med Virol 2013; 85:815-822.
-
(2013)
J Med Virol
, vol.85
, pp. 815-822
-
-
Avá, A.P.1
Água-Doce, I.2
Andrade, A.3
Pádua, E.4
-
9
-
-
84880299420
-
NS5A inhibitors in the treatment of hepatitis C
-
Pawlotsky JM. NS5A inhibitors in the treatment of hepatitis C. J Hepatol 2013; 59:375-382.
-
(2013)
J Hepatol
, vol.59
, pp. 375-382
-
-
Pawlotsky, J.M.1
-
10
-
-
84861546211
-
Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus non-structural protein 5A replication complex inhibitor, BMS-79005
-
Sun JH, O'Boyle DR, II, Zhang Y, et al. Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus non-structural protein 5A replication complex inhibitor, BMS-79005. Hepatology 2012; 55:1692-1699.
-
(2012)
Hepatology
, vol.55
, pp. 1692-1699
-
-
Sun, J.H.1
O'Boyle, D.R.2
Zhang, Y.3
-
11
-
-
84894897183
-
IDX719, HCV NS5A inhibitor, demonstrates pan-genotypic activity after three days of monotherapy in genotype 1, 2, 3 or 4 HCV-infected subject
-
Mayers DL, Vince B, Hill JM, et al. IDX719, HCV NS5A inhibitor, demonstrates pan-genotypic activity after three days of monotherapy in genotype 1, 2, 3 or 4 HCV-infected subject. Hepatology 2012; 56:1020A.
-
(2012)
Hepatology
, vol.56
-
-
Mayers, D.L.1
Vince, B.2
Hill, J.M.3
-
12
-
-
84875804486
-
Natural prevalence of NS5A polymorphisms in subjects infected with hepatitis C virus genotype 3 and their effects on the antiviral activity of NS5A inhibitors
-
Hernandez D, Zhou N, Ueland J, et al. Natural prevalence of NS5A polymorphisms in subjects infected with hepatitis C virus genotype 3 and their effects on the antiviral activity of NS5A inhibitors. J Clin Virol 2013; 57:13-18.
-
(2013)
J Clin Virol
, vol.57
, pp. 13-18
-
-
Hernandez, D.1
Zhou, N.2
Ueland, J.3
-
13
-
-
84872021404
-
In vitro activity of daclatasvir on hepatitis C virus genotype 3 NS5A
-
Wang C, Valera L, Jia L, Kirk MJ, Gao M, Fridell RA. in vitro activity of daclatasvir on hepatitis C virus genotype 3 NS5A. Antimicrob Agents Chemother 2013; 57:611-613.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 611-613
-
-
Wang, C.1
Valera, L.2
Jia, L.3
Kirk, M.J.4
Gao, M.5
Fridell, R.A.6
-
14
-
-
84863156581
-
In vitro activity of BMS-790052 on hepatitis C virus genotype 4 NS5A
-
Wang C, Lingling L, Huang H, et al. in vitro activity of BMS-790052 on hepatitis C virus genotype 4 NS5A. Antimicrob Agents Chemother 2012; 56:1588-1590.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 1588-1590
-
-
Wang, C.1
Lingling, L.2
Huang, H.3
-
15
-
-
84858415895
-
Prevalence of natural polymorphisms at the HCV NS5A gene associated with resistance to daclatasvir, an NS5A inhibitor
-
Plaza Z, Soriano V, Vispo E, et al. Prevalence of natural polymorphisms at the HCV NS5A gene associated with resistance to daclatasvir, an NS5A inhibitor. Antivir Ther 2012; 17:921-926.
-
(2012)
Antivir Ther
, vol.17
, pp. 921-926
-
-
Plaza, Z.1
Soriano, V.2
Vispo, E.3
-
16
-
-
84863860109
-
Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b
-
Suzuki F, Sezaki H, Akuta N, et al. Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b. J Clin Virol 2012; 54:352-354.
-
(2012)
J Clin Virol
, vol.54
, pp. 352-354
-
-
Suzuki, F.1
Sezaki, H.2
Akuta, N.3
-
17
-
-
84880931245
-
Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir
-
Karino Y, Toyota J, Ikeda K, et al. Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir. J Hepatol 2013; 58:646-654.
-
(2013)
J Hepatol
, vol.58
, pp. 646-654
-
-
Karino, Y.1
Toyota, J.2
Ikeda, K.3
-
18
-
-
84927725089
-
-
(Accessed 30 September 2013.) Available from
-
Max Planck Institut Informatik. geno2pheno. (Accessed 30 September 2013.) Available from www.geno2pheno.org
-
Max Planck Institut Informatik
-
-
|