Copy number variation in schizophrenia

Neuropsychopharmacology

Volumn 40, Issue 1, 2015, Pages 252-254

  Gulsuner, Suleyman ^a   McClellan, Jon M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COPY NUMBER VARIATION; EVOLUTION; GENE LOCUS; GENE MUTATION; GENETIC VARIABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN GENOME; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SCHIZOPHRENIA; SEGMENTAL DUPLICATION; ANIMAL; GENETIC VARIATION; GENETICS;

ANIMALS; DNA COPY NUMBER VARIATIONS; GENETIC VARIATION; HUMANS; SCHIZOPHRENIA;

EID: 84926655754     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.216     Document Type: Article

References (6)

1. Malhotra D, Sebat J (2012). CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell 148: 1223-1241.
2. Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, Cooper GM et al. (2008). Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 320: 539-543.
3. Rippey C, Walsh T, Gulsuner S, Brodsky M, Nord AS, Gasperini M et al. (2013). Formation of chimeric genes by copy-number variation as a mutational mechanism in schizophrenia. Am J Hum Genet 93: 697-710.
4. Stefansson H, Meyer-Lindenberg A, Steinberg S, Magnusdottir B, Morgen K, Arnarsdottir S et al. (2014). CNVs conferring risk of autism or schizophrenia affect cognition in controls. Nature 505: 361-366.
5. McClellan J, King MC (2010). Genetic heterogeneity in human disease. Cell 141: 210-217.
6. Kirov G, Pocklington AJ, Holmans P, Ivanov D, Ikeda M, Ruderfer D et al. (2012). De novo CNV analysis implicates specific abnormalities of postsynaptic signaling complexes in the pathogenesis of schizophrenia. Mol Psychiatry 17: 142-153.