-
1
-
-
0002000533
-
Heavy metals and heavy-metal antagonists
-
Gilman (ed.). McGraw-Hill, New York, NY
-
Klaassen CD: Heavy metals and heavy-metal antagonists. In: The Pharmacological Basis of Therapeutics. Gilman (ed.). McGraw-Hill, New York, NY, pp 649-1672, 1996.
-
(1996)
The Pharmacological Basis of Therapeutics
, pp. 649-1672
-
-
Klaassen, C.D.1
-
2
-
-
34948874719
-
Arsenic patent keeps drug for rare cancer out of reach of many
-
Cyranoski D: Arsenic patent keeps drug for rare cancer out of reach of many. Nat Med 13: 1005, 2007.
-
(2007)
Nat Med
, vol.13
, pp. 1005
-
-
Cyranoski, D.1
-
4
-
-
0032773828
-
Induction of apoptosis and inhibition of human gastric cancer MGC-803 cell growth by arsenic trioxide
-
Zhang TC, Cao EH, Li JF, Ma W and Qin JF: Induction of apoptosis and inhibition of human gastric cancer MGC-803 cell growth by arsenic trioxide. Eur J Cancer 35: 1258-1263, 1999.
-
(1999)
Eur J Cancer
, vol.35
, pp. 1258-1263
-
-
Zhang, T.C.1
Cao, E.H.2
Li, J.F.3
Ma, W.4
Qin, J.F.5
-
5
-
-
0034133665
-
The alteration of mitochondria is an early event of arsenic trioxide induced apoptosis in esophageal carcinoma cells
-
Shen ZY, Shen J, Cai WJ, Hong C and Zheng MH: The alteration of mitochondria is an early event of arsenic trioxide induced apoptosis in esophageal carcinoma cells. Int J Mol Med 5: 155-158, 2000.
-
(2000)
Int J Mol Med
, vol.5
, pp. 155-158
-
-
Shen, Z.Y.1
Shen, J.2
Cai, W.J.3
Hong, C.4
Zheng, M.H.5
-
6
-
-
0033066323
-
Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro
-
Akao Y, Nakagawa Y and Akiyama K: Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro. FEBS Lett 455: 59-62, 1999.
-
(1999)
FEBS Lett
, vol.455
, pp. 59-62
-
-
Akao, Y.1
Nakagawa, Y.2
Akiyama, K.3
-
7
-
-
0034490080
-
Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines
-
Uslu R, Sanli UA, Sezgin C, Karabulut B, Terzioglu E, Omay SB and Goker E: Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines. Clin Cancer Res 6: 4957-4964, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4957-4964
-
-
Uslu, R.1
Sanli, U.A.2
Sezgin, C.3
Karabulut, B.4
Terzioglu, E.5
Omay, S.B.6
Goker, E.7
-
8
-
-
16644398131
-
3) on human breast cancer cells
-
Chow SK, Chan JY and Fung KP: Inhibition of cell proliferation and the action mechanisms of arsenic trioxide (As2O3) on human breast cancer cells. J Cell Biochem 93: 173-187, 2004.
-
(2004)
J Cell Biochem
, vol.93
, pp. 173-187
-
-
Chow, S.K.1
Chan, J.Y.2
Fung, K.P.3
-
9
-
-
33644980607
-
Inhibition of mitogen-activated protein kinase kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells
-
Ye J, Li A, Liu Q, Wang X and Zhou J: Inhibition of mitogen-activated protein kinase kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells. Clin Exp Pharmacol Physiol 32: 1042-1048, 2005.
-
(2005)
Clin Exp Pharmacol Physiol
, vol.32
, pp. 1042-1048
-
-
Ye, J.1
Li, A.2
Liu, Q.3
Wang, X.4
Zhou, J.5
-
10
-
-
0037474225
-
Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells
-
Crociani O, Guasti L, Balzi M, et al: Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells. J Biol Chem 278: 2947-2955, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 2947-2955
-
-
Crociani, O.1
Guasti, L.2
Balzi, M.3
-
11
-
-
49449109702
-
Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells
-
Guasti L, Crociani O, Redaelli E, Pillozzi S, PolVani S, Masselli M, Mello T, Galli A, Amedei A, Wymore RS, et al: Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells. Mol Cell Biol 28: 5043-5060, 2008.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5043-5060
-
-
Guasti, L.1
Crociani, O.2
Redaelli, E.3
Pillozzi, S.4
Polvani, S.5
Masselli, M.6
Mello, T.7
Galli, A.8
Amedei, A.9
Wymore, R.S.10
-
12
-
-
23844547384
-
Expression and role of hERG channels in cancer cells
-
Arcangeli A: Expression and role of hERG channels in cancer cells. Novartis Found Symp 266: 225-232, 2005.
-
(2005)
Novartis Found Symp
, vol.266
, pp. 225-232
-
-
Arcangeli, A.1
-
13
-
-
79953281990
-
Arsenic trioxide induces the apoptosis of human breast cancer MCF-7 cells through activation of caspase-3 and inhibition of HERG channels
-
Wang Y, Zhang Y, Yang L, Cai B, Li J, Zhou Y, Yin L, Yang L, Yang BF and Lu YJ: Arsenic trioxide induces the apoptosis of human breast cancer MCF-7 cells through activation of caspase-3 and inhibition of HERG channels. Exp Ther Med 2: 481-486, 2011.
-
(2011)
Exp Ther Med
, vol.2
, pp. 481-486
-
-
Wang, Y.1
Zhang, Y.2
Yang, L.3
Cai, B.4
Li, J.5
Zhou, Y.6
Yin, L.7
Yang, L.8
Yang, B.F.9
Lu, Y.J.10
-
14
-
-
67649448828
-
MiR-145 inhibits breast cancer cell growth through RTKN
-
Wang S, Bian C, Yang Z, Bo Y, Li J, Zeng L, Zhou H and Zhao RC: miR-145 inhibits breast cancer cell growth through RTKN. Int J Oncol 34: 1461-1466, 2009.
-
(2009)
Int J Oncol
, vol.34
, pp. 1461-1466
-
-
Wang, S.1
Bian, C.2
Yang, Z.3
Bo, Y.4
Li, J.5
Zeng, L.6
Zhou, H.7
Zhao, R.C.8
-
15
-
-
67649979858
-
The mir-34 microRNA is required for the DNA damage response in vivo in C. Elegans and in vitro in human breast cancer cells
-
Kato M, Paranjape T, Müller RU, Nallur S, Gillespie E, Keane K, Esquela-Kerscher A, Weidhaas JB and Slack FJ: The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells. Oncogene 28: 2419-2424, 2009.
-
(2009)
Oncogene
, vol.28
, pp. 2419-2424
-
-
Kato, M.1
Paranjape, T.2
Müller, R.U.3
Nallur, S.4
Gillespie, E.5
Keane, K.6
Esquela-Kerscher, A.7
Weidhaas, J.B.8
Slack, F.J.9
-
16
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, Vadas MA, Khew-Goodall Y and Goodall GJ: The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10: 593-601, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Vadas, M.A.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
17
-
-
66449095667
-
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis
-
Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szász AM, Wang ZC, Brock JE, Richardson AL and Weinberg RA: A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 137: 1032-1046, 2009.
-
(2009)
Cell
, vol.137
, pp. 1032-1046
-
-
Valastyan, S.1
Reinhardt, F.2
Benaich, N.3
Calogrias, D.4
Szász, A.M.5
Wang, Z.C.6
Brock, J.E.7
Richardson, A.L.8
Weinberg, R.A.9
-
18
-
-
54249132168
-
Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal
-
Wu G, Qiu XL, Zhou L, Zhu J, Chamberlin R, Lau J, Chen PL and Lee WH: Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res 68: 8393-8399, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 8393-8399
-
-
Wu, G.1
Qiu, X.L.2
Zhou, L.3
Zhu, J.4
Chamberlin, R.5
Lau, J.6
Chen, P.L.7
Lee, W.H.8
-
19
-
-
34147095310
-
The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2
-
Yang B, Lin H, Xiao J, Lu Y, Luo X, Li B, Zhang Y, Xu C, Bai Y, Wang H, et al: The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med 13: 486-491, 2007.
-
(2007)
Nat Med
, vol.13
, pp. 486-491
-
-
Yang, B.1
Lin, H.2
Xiao, J.3
Lu, Y.4
Luo, X.5
Li, B.6
Zhang, Y.7
Xu, C.8
Bai, Y.9
Wang, H.10
-
20
-
-
78650701405
-
MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation
-
Lu Y, Zhang Y, Wang N, Pan Z, Gao X, Zhang F, Zhang Y, Shan H, Luo X, Bai Y, et al: MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation. Circulation 122: 2378-2387, 2010.
-
(2010)
Circulation
, vol.122
, pp. 2378-2387
-
-
Lu, Y.1
Zhang, Y.2
Wang, N.3
Pan, Z.4
Gao, X.5
Zhang, F.6
Zhang, Y.7
Shan, H.8
Luo, X.9
Bai, Y.10
-
21
-
-
67651111989
-
Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines
-
Shan H, Zhang Y, Lu Y, Zhang Y, Pan Z, Cai B, Wang N, Li X, Feng T, Hong Y, et al: Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines. Cardiovasc Res 83: 465-472, 2009.
-
(2009)
Cardiovasc Res
, vol.83
, pp. 465-472
-
-
Shan, H.1
Zhang, Y.2
Lu, Y.3
Zhang, Y.4
Pan, Z.5
Cai, B.6
Wang, N.7
Li, X.8
Feng, T.9
Hong, Y.10
-
22
-
-
77950647746
-
The roles of microRNAs in heart diseases: A novel important regulator
-
Cai B, Pan Z and Lu Y: The roles of microRNAs in heart diseases: A novel important regulator. Curr Med Chem 17: 407-411, 2010.
-
(2010)
Curr Med Chem
, vol.17
, pp. 407-411
-
-
Cai, B.1
Pan, Z.2
Lu, Y.3
-
23
-
-
84924271853
-
Global cancer statistics, 2012
-
Epub ahead of print
-
Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA Cancer J Clin: Feb 4, 2015 (Epub ahead of print).
-
(2015)
CA Cancer J Clin: Feb
, vol.4
-
-
Torre, L.A.1
Bray, F.2
Siegel, R.L.3
Ferlay, J.4
Lortet-Tieulent, J.5
Jemal, A.6
-
24
-
-
67649908927
-
Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
-
Vahdat LT, Pruitt B, Fabian CJ, Rivera RR, Smith DA, Tan-Chiu E, Wright J, Tan AR, Dacosta NA, Chuang E, et al: Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. J Clin Oncol 27: 2954-2961, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2954-2961
-
-
Vahdat, L.T.1
Pruitt, B.2
Fabian, C.J.3
Rivera, R.R.4
Smith, D.A.5
Tan-Chiu, E.6
Wright, J.7
Tan, A.R.8
Dacosta, N.A.9
Chuang, E.10
-
25
-
-
46149092982
-
HERG K+ channel expression in CD34+/CD38-/CD123(high) cells and primary leukemia cells and analysis of its regulation in leukemia cells
-
Li H, Liu L, Guo L, et al: HERG K+ channel expression in CD34+/CD38-/CD123(high) cells and primary leukemia cells and analysis of its regulation in leukemia cells. Int J Hematol 87: 387-392, 2008.
-
(2008)
Int J Hematol
, vol.87
, pp. 387-392
-
-
Li, H.1
Liu, L.2
Guo, L.3
-
26
-
-
70350001105
-
Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration
-
Afrasiabi E, Hietamäki M, Viitanen T, Sukumaran P, Bergelin N and Törnquist K: Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration. Cell Signal 22: 57-64, 2010.
-
(2010)
Cell Signal
, vol.22
, pp. 57-64
-
-
Afrasiabi, E.1
Hietamäki, M.2
Viitanen, T.3
Sukumaran, P.4
Bergelin, N.5
Törnquist, K.6
-
27
-
-
37549072709
-
Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo
-
Zhao J, Wei XL, Jia YS and Zheng JQ: Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo. Eur J Pharmacol 579: 50-57, 2008.
-
(2008)
Eur J Pharmacol
, vol.579
, pp. 50-57
-
-
Zhao, J.1
Wei, X.L.2
Jia, Y.S.3
Zheng, J.Q.4
-
28
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, Magri E, Pedriali M, Fabbri M, Campiglio M, et al: MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65: 7065-7070, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 7065-7070
-
-
Iorio, M.V.1
Ferracin, M.2
Liu, C.G.3
Veronese, A.4
Spizzo, R.5
Sabbioni, S.6
Magri, E.7
Pedriali, M.8
Fabbri, M.9
Campiglio, M.10
-
29
-
-
67649448828
-
MiR-145 inhibits breast cancer cell growth through RTKN
-
Wang S, Bian C, Yang Z, Bo Y, Li J, Zeng L, Zhou H and Zhao RC: miR-145 inhibits breast cancer cell growth through RTKN. Int J Oncol 34: 1461-1466, 2009.
-
(2009)
Int J Oncol
, vol.34
, pp. 1461-1466
-
-
Wang, S.1
Bian, C.2
Yang, Z.3
Bo, Y.4
Li, J.5
Zeng, L.6
Zhou, H.7
Zhao, R.C.8
-
30
-
-
77952944048
-
MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer
-
Kong W, He L, Coppola M, Guo J, Esposito NN, Coppola D and Cheng JQ: MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. J Biol Chem 285: 17869-17879, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 17869-17879
-
-
Kong, W.1
He, L.2
Coppola, M.3
Guo, J.4
Esposito, N.N.5
Coppola, D.6
Cheng, J.Q.7
-
31
-
-
77950905590
-
MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression
-
Song B, Wang C, Liu J, Wang X, Lv L, Wei L, Xie L, Zheng Y and Song X: MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression. J Exp Clin Cancer Res 29: 29, 2010.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 29
-
-
Song, B.1
Wang, C.2
Liu, J.3
Wang, X.4
Lv, L.5
Wei, L.6
Xie, L.7
Zheng, Y.8
Song, X.9
-
32
-
-
38049046644
-
Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors
-
Lee EJ, Baek M, Gusev Y, Brackett DJ, Nuovo GJ and Schmittgen TD: Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors. RNA 14: 35-42, 2008.
-
(2008)
RNA
, vol.14
, pp. 35-42
-
-
Lee, E.J.1
Baek, M.2
Gusev, Y.3
Brackett, D.J.4
Nuovo, G.J.5
Schmittgen, T.D.6
-
33
-
-
84867433208
-
MiR-328 expression is decreased in high-grade gliomas and is associated with worse survival in primary glioblastoma
-
Wu Z, Sun L, Wang H, Yao J, Jiang C, Xu W and Yang Z: MiR-328 expression is decreased in high-grade gliomas and is associated with worse survival in primary glioblastoma. PLoS One 7: e47270, 2012.
-
(2012)
PLoS One
, vol.7
, pp. e47270
-
-
Wu, Z.1
Sun, L.2
Wang, H.3
Yao, J.4
Jiang, C.5
Xu, W.6
Yang, Z.7
-
34
-
-
79954987192
-
5-Fluorouracil drug alters the microRNA expression profiles in MCF-7 breast cancer cells
-
Shah MY, Pan X, Fix LN, Farwell MA and Zhang B: 5-Fluorouracil drug alters the microRNA expression profiles in MCF-7 breast cancer cells. J Cell Physiol 226: 1868-1878, 2011.
-
(2011)
J Cell Physiol
, vol.226
, pp. 1868-1878
-
-
Shah, M.Y.1
Pan, X.2
Fix, L.N.3
Farwell, M.A.4
Zhang, B.5
-
35
-
-
77649133970
-
MiR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts
-
Eiring AM, Harb JG, Neviani P, Garton C, Oaks JJ, Spizzo R, Liu S, Schwind S, Santhanam R, Hickey CJ, et al: miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell 140: 652-665, 2010.
-
(2010)
Cell
, vol.140
, pp. 652-665
-
-
Eiring, A.M.1
Harb, J.G.2
Neviani, P.3
Garton, C.4
Oaks, J.J.5
Spizzo, R.6
Liu, S.7
Schwind, S.8
Santhanam, R.9
Hickey, C.J.10
-
36
-
-
66849113786
-
MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells
-
Pan YZ, Morris ME and Yu AM: MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells. Mol Pharmacol 75: 1374-1379, 2009.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1374-1379
-
-
Pan, Y.Z.1
Morris, M.E.2
Yu, A.M.3
-
37
-
-
84872763413
-
Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328
-
Paduano F, Dattilo V, Narciso D, Bilotta A, Gaudio E, Menniti M, Agosti V, Palmieri C, Perrotti N, Fusco A, et al: Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328. FEBS J 280: 401-412, 2013.
-
(2013)
FEBS J
, vol.280
, pp. 401-412
-
-
Paduano, F.1
Dattilo, V.2
Narciso, D.3
Bilotta, A.4
Gaudio, E.5
Menniti, M.6
Agosti, V.7
Palmieri, C.8
Perrotti, N.9
Fusco, A.10
|