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Volumn 23, Issue 4, 2015, Pages 612-

Transduction of antigen-presenting cells in the brain by AAV9 warrants caution in preclinical studies

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DECARBOXYLASE; GREEN FLUORESCENT PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PARVOVIRUS VECTOR;

EID: 84926625888     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2015.35     Document Type: Letter
Times cited : (9)

References (8)
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    • Hinderer, C, Bell, P, Vite, CH, Louboutin, J-P, Grant, R, Bote, E et al. (2014). Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna. Mol Ther Methods Clin Dev 1: 14051.
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    • Hinderer, C.1    Bell, P.2    Vite, C.H.3    Louboutin, J.-P.4    Grant, R.5    Bote, E.6
  • 2
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    • Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates
    • Samaranch, L, Salegio, EA, San Sebastian, W, Kells, AP, Bringas, JR, Forsayeth, J et al. (2013). Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates. Hum Gene Ther 24: 526-532.
    • (2013) Hum Gene Ther , vol.24 , pp. 526-532
    • Samaranch, L.1    Salegio, E.A.2    San Sebastian, W.3    Kells, A.P.4    Bringas, J.R.5    Forsayeth, J.6
  • 3
    • 84893307092 scopus 로고    scopus 로고
    • AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction
    • Samaranch, L, San Sebastian, W, Kells, AP, Salegio, EA, Heller, G, Bringas, JR et al. (2014). AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction. Mol Ther 22: 329-337.
    • (2014) Mol Ther , vol.22 , pp. 329-337
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  • 4
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    • Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses
    • Gao, G, Wang, Q, Calcedo, R, Mays, L, Bell, P, Wang, L et al. (2009). Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses. Hum Gene Ther 20: 930-942.
    • (2009) Hum Gene Ther , vol.20 , pp. 930-942
    • Gao, G.1    Wang, Q.2    Calcedo, R.3    Mays, L.4    Bell, P.5    Wang, L.6
  • 5
    • 84871922836 scopus 로고    scopus 로고
    • Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses
    • Ciesielska, A, Hadaczek, P, Mittermeyer, G, Zhou, S, Wright, JF, Bankiewicz, KS et al. (2013). Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses. Mol Ther 21: 158-166.
    • (2013) Mol Ther , vol.21 , pp. 158-166
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  • 6
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    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen, M and Bujard, H (1992). Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89: 5547-5551.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
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  • 7
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    • In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9
    • Swiech, L, Heidenreich, M, Banerjee, A, Habib, N, Li, Y, Trombetta, J et al. (2015). In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9. Nat Biotechnol 33: 102-106.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.