Urinary CD80 levels as a diagnostic biomarker of minimal change disease

Pediatric Nephrology

Volumn 30, Issue 2, 2014, Pages 309-316

  Ling, Chen ^a   Liu, Xiaorong ^a   Shen, Ying ^a   Chen, Zhi ^a   Fan, Jianfeng ^a   Jiang, Yeping ^a   Meng, Qun ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

CD80; Children; FSGS; MCD

Indexed keywords

B7 ANTIGEN; BIOLOGICAL MARKER;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; CREATININE URINE LEVEL; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOCAL GLOMERULOSCLEROSIS; HUMAN; HUMAN TISSUE; INFANT; KIDNEY BIOPSY; MAJOR CLINICAL STUDY; MALE; MINIMAL CHANGE DISEASE; MINIMAL CHANGE GLOMERULONEPHRITIS; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; AREA UNDER THE CURVE; LIPOID NEPHROSIS; PRESCHOOL CHILD; URINE;

ANTIGENS, CD80; AREA UNDER CURVE; BIOLOGICAL MARKERS; CHILD; CHILD, PRESCHOOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; NEPHROSIS, LIPOID; ROC CURVE;

EID: 84926619908     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-014-2915-3     Document Type: Article

References (23)

1. International Study of Kidney Disease in Children (1978) Nephrotic syndrome in children: prediction of histopathology from clinical and laboratory characteristics at time of diagnosis. A report of the International Study of Kidney Disease in Children. Kidney Int 13: 159-165
2. International Study of Kidney Disease in Children (1981) The primary nephrotic syndrome in children. Identification of patients with minimal change nephrotic syndrome from i n i t i a l r e spons e t o predni sone. A r e p o r t of the International Study of Kidney Disease in Children. J Pediatr 98:561-564
3. Rianthavorn P, Kerr SJ, Chiengthong K (2014) Safety of pediatric percutaneous native kidney biopsy and factors predicting bleeding complications. Nephrology (Carlton) 19: 143-148
4. Greenwald RJ, Freeman GJ, Sharpe AH (2005) The B7 family revisited. Annu Rev Immunol 23:515-548
5. Chang JM, Hwang DY, Chen SC, Kuo MC, Hung CC, Hwang SJ, Tsai JC, Chen HC (2013) B7-1 expression regulates the hypoxiadriven cytoskeleton rearrangement in glomerular podocytes. Am J Physiol Renal Physiol 304:F127-F136
6. Reiser J, von Gersdorff G, Loos M, Oh J, Asanuma K, Giardino L, Rastaldi MP, Calvaresi N, Watanabe H, Schwarz K, Faul C, Kretzler M, Davidson A, Sugimoto H, Kalluri R, Sharpe AH, Kreidberg JA, Mundel P (2004) Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest 113:1390-1397
7. Garin EH, Diaz LN, MuW, Wasserfall C, Araya C, SegalM, Johnson RJ (2009) Urinary CD80 excretion increases in idiopathic minimalchange disease. J Am Soc Nephrol 20:260-266
8. Garin EH, Mu W, Arthur JM, Rivard CJ, Araya CE, Shimada M, Johnson RJ (2010) Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis. Kidney Int 78:296-302
9. Kistler AD, Reiser J (2010) Maximal ‘CD80-uria’ with minimal change. Kidney Int 78:236-238
10. Churg J, Habib R, White RH (1970) Pathology of the nephrotic syndrome in children: a report for the International Study of Kidney Disease in Children. Lancet 760:1299-1302
11. Reiser J, Mundel P (2004) Danger signaling by glomerular podocytes defines a novel function of inducible B7-1 in the pathogenesis of nephrotic syndrome. J Am Soc Nephrol 15: 2246-2248
12. Eto N, Wada T, Inagi R, Takano H, Shimizu A, Kato H, Kurihara H, Kawachi H, Shankland SJ, Fujita T, Nangaku M (2007) Podocyte protection by darbepoetin: preservation of the cytoskeleton and nephrin expression. Kidney Int 72:455-463
13. Shimada M, Araya C, Rivard C, Ishimoto T, Johnson RJ, Garin EH (2011) Minimal change disease: a “two-hit” podocyte immune disorder? Pediatr Nephrol 26(4):645-649
14. Kow NY, Mak A (2013) Costimulatory pathways: physiology and potential therapeutic manipulation in systemic lupus erythematosus. Clin Dev Immunol 2013:245-928
15. Merrill JT (2013) Co-stimulatory molecules as targets for treatment of lupus. Clin Immunol 148(3):369-375
16. Wong CK, Lit LC, Tam LS, Li EK, Lam CW (2005) Aberrant production of soluble costimulatory molecules CTLA-4, CD28, CD80 and CD86 in patients with systemic lupus erythematosus. Rheumatology 44:989-994
17. Meyrier A, Niaudet P (2005) Minimal changes and focal segmental glomerulosclerosis. In: Davison AM, Cameron SJ, Grunfeld JP, Ponticelli C, Ritz E, Winearls C, Van Ypersele C (eds) Textbook of clinical nephrology. Oxford University Press, Oxford, pp 439-469
18. Haas M, Yousefzadeh N (2002) Glomerular tip lesion in minimal change nephropathy: a study of autopsies before 1950. Am J Kidney Dis 39:1168-1175
19. Howie AJ, Brewer DB (1984) The glomerular tip lesion: a previously undescribed type of segmental glomerular abnormality. J Pathol 142: 205-220
20. Howie AJ, Lee SJ, Green NJ, Newbold KM, Kizaki T, Koram A, Richards NT, Michael J, Adu D (1993) Different clinicopathological types of segmental sclerosing glomerular lesions in adults. Nephrol Dial Transplant 8:590-599
21. D’Agati VD, Kaskel FJ, Falk RJ (2011) Focal segmental glomerulosclerosis. N Engl J Med 365:2398-2411
22. Sinha A, Bajpai J, Saini S, Bhatia D, Gupta A, Puraswani M, Dinda AK, Agarwal SK, Sopory S, Pandey RM, Hari P, Bagga A (2014) Serum-soluble urokinase receptor levels do not distinguish focal segmental glomerulosclerosis from other causes of nephrotic syndrome in children. Kidney Int 85:649-658
23. Cara-Fuentes G, Wei C, Segarra A, Segarra A, Ishimoto T, Rivard C, Johnson RJ, Reiser J, Garin EH (2014) CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance. Pediatr Nephrol 29:1363-1371