메뉴 건너뛰기




Volumn 6, Issue JAN, 2015, Pages

Differential signaling during macropinocytosis in response to M-CSF and PMA in macrophages

Author keywords

diacylglycerol; Macropinocytosis; Phosphatidylinositol (3,4,5) trisphosphate; Phospholipase C; Protein kinase C; Ras

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; CALPHOSTIN C; COLONY STIMULATING FACTOR 1; DIACYLGLYCEROL; FLUORESCENT DYE; LIPID; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; PROTEIN KINASE C; RAS PROTEIN; ROTTLERIN; SALIRASIB;

EID: 84926454260     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2015.00008     Document Type: Article
Times cited : (44)

References (45)
  • 1
    • 0029804116 scopus 로고    scopus 로고
    • Mechanism of activation of protein kinase B by insulin and IGF-1
    • Alessi, D. R., Andjelkovic, M., Caudwell, B., Cron, P., Morrice, N., Cohen, P., et al. (1996). Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15, 6541-6551.
    • (1996) EMBO J , vol.15 , pp. 6541-6551
    • Alessi, D.R.1    Andjelkovic, M.2    Caudwell, B.3    Cron, P.4    Morrice, N.5    Cohen, P.6
  • 2
    • 0033783042 scopus 로고    scopus 로고
    • Constitutive macropinocytosis in oncogene-transformed fibroblasts depends on sequential permanent activation phosphoinositide 3-kinase and phospholipase C
    • Amyere, M., Payrastre, B., Krause, U., Van Der Smissen, P., Veithen, A., and Courtoy, P. J. (2000). Constitutive macropinocytosis in oncogene-transformed fibroblasts depends on sequential permanent activation phosphoinositide 3-kinase and phospholipase C. Mol. Biol. Cell 11, 3453-3467. doi: 10.1091/mbc.11.10.3453
    • (2000) Mol. Biol. Cell , vol.11 , pp. 3453-3467
    • Amyere, M.1    Payrastre, B.2    Krause, U.3    Van Der Smissen, P.4    Veithen, A.5    Courtoy, P.J.6
  • 3
    • 0030459125 scopus 로고    scopus 로고
    • A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis in macrophages
    • Araki, N., Johnson, M. T., and Swanson, J. A. (1996). A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis in macrophages. J. Cell Biol. 135, 1249-1260. doi: 10.1083/jcb.135.5.1249
    • (1996) J. Cell Biol. , vol.135 , pp. 1249-1260
    • Araki, N.1    Johnson, M.T.2    Swanson, J.A.3
  • 4
    • 36549040859 scopus 로고    scopus 로고
    • The selectivity of protein kinase inhibitors: a further update
    • Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C. J., McLauchlan, H., et al. (2007). The selectivity of protein kinase inhibitors: a further update. Biochem. J. 408, 297-315. doi: 10.1042/BJ20070797
    • (2007) Biochem. J. , vol.408 , pp. 297-315
    • Bain, J.1    Plater, L.2    Elliott, M.3    Shpiro, N.4    Hastie, C.J.5    McLauchlan, H.6
  • 5
    • 84870236441 scopus 로고    scopus 로고
    • Trypanosoma cruzi uses macropinocytosis as an additional entry pathway into mammalian host cell
    • Barrias, E. S., Reignault, L. C., De Souza, W., and Carvalho, T. M. (2012). Trypanosoma cruzi uses macropinocytosis as an additional entry pathway into mammalian host cell. Microbes Infect. 14, 1340-1351. doi: 10.1016/j.micinf.2012.08.003
    • (2012) Microbes Infect , vol.14 , pp. 1340-1351
    • Barrias, E.S.1    Reignault, L.C.2    De Souza, W.3    Carvalho, T.M.4
  • 6
    • 0022470480 scopus 로고
    • Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins
    • Bar-Sagi, D., and Feramisco, J. R. (1986). Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins. Science 233, 1061-1066. doi: 10.1126/science.3090687
    • (1986) Science , vol.233 , pp. 1061-1066
    • Bar-Sagi, D.1    Feramisco, J.R.2
  • 7
    • 33745183370 scopus 로고    scopus 로고
    • A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis
    • Beemiller, P., Hoppe, A. D., and Swanson, J. A. (2006). A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis. PLoS Biol. 4:e162. doi: 10.1371/journal.pbio.0040162
    • (2006) PLoS Biol , vol.4
    • Beemiller, P.1    Hoppe, A.D.2    Swanson, J.A.3
  • 8
    • 76049108692 scopus 로고    scopus 로고
    • A Cdc42 activation cycle coordinated by PI 3-kinase during Fc receptor-mediated phagocytosis
    • Beemiller, P., Zhang, Y., Mohan, S., Levinsohn, E., Gaeta, I., Hoppe, A. D., et al. (2010). A Cdc42 activation cycle coordinated by PI 3-kinase during Fc receptor-mediated phagocytosis. Mol. Biol. Cell 21, 470-480. doi: 10.1091/mbc.E08-05-0494
    • (2010) Mol. Biol. Cell , vol.21 , pp. 470-480
    • Beemiller, P.1    Zhang, Y.2    Mohan, S.3    Levinsohn, E.4    Gaeta, I.5    Hoppe, A.D.6
  • 9
    • 0034739859 scopus 로고    scopus 로고
    • Localized biphasic changes in phosphatidylinositol-4 5-bisphosphate at sites of phagocytosis
    • Botelho, R. J., Teruel, M., Dierckman, R., Anderson, R., Wells, A., York, J. D., et al. (2000). Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. J. Cell Biol. 151, 1353-1367. doi: 10.1083/jcb.151.7.1353
    • (2000) J. Cell Biol. , vol.151 , pp. 1353-1367
    • Botelho, R.J.1    Teruel, M.2    Dierckman, R.3    Anderson, R.4    Wells, A.5    York, J.D.6
  • 10
    • 79960055459 scopus 로고    scopus 로고
    • RAS interaction with PI3K: more than just another effector pathway
    • Castellano, E., and Downward, J. (2011). RAS interaction with PI3K: more than just another effector pathway. Genes Cancer 2, 261-274. doi: 10.1177/1947601911408079
    • (2011) Genes Cancer , vol.2 , pp. 261-274
    • Castellano, E.1    Downward, J.2
  • 11
    • 84878396462 scopus 로고    scopus 로고
    • Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
    • Commisso, C., Davidson, S. M., Soydaner-Azeloglu, R. G., Parker, S. J., Kamphorst, J. J., Hackett, S., et al. (2013). Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature 497, 633-637. doi: 10.1038/nature12138
    • (2013) Nature , vol.497 , pp. 633-637
    • Commisso, C.1    Davidson, S.M.2    Soydaner-Azeloglu, R.G.3    Parker, S.J.4    Kamphorst, J.J.5    Hackett, S.6
  • 12
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies, S. P., Reddy, H., Caivano, M., and Cohen, P. (2000). Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105. doi: 10.1042/0264-6021:3510095
    • (2000) Biochem. J. , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 13
    • 84907062564 scopus 로고    scopus 로고
    • Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation
    • Egami, Y., Taguchi, T., Maekawa, M., Arai, H., and Araki, N. (2014). Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation. Front. Physiol. 5:374. doi: 10.3389/fphys.2014.00374
    • (2014) Front. Physiol. , vol.5 , pp. 374
    • Egami, Y.1    Taguchi, T.2    Maekawa, M.3    Arai, H.4    Araki, N.5
  • 14
    • 0032518666 scopus 로고    scopus 로고
    • Activation of phospholipase Cg by PI 3-kinase-induced PH domain-mediated membrane targeting
    • Falasca, M., Logan, S. K., Lehto, V. P., Baccante, G., Lemmon, M. A., and Schlessinger, J. (1998). Activation of phospholipase Cg by PI 3-kinase-induced PH domain-mediated membrane targeting. EMBO J. 17, 414-422. doi: 10.1093/emboj/17.2.414
    • (1998) EMBO J , vol.17 , pp. 414-422
    • Falasca, M.1    Logan, S.K.2    Lehto, V.P.3    Baccante, G.4    Lemmon, M.A.5    Schlessinger, J.6
  • 15
    • 84897071551 scopus 로고    scopus 로고
    • Fluorescently labeled methyl-beta-cyclodextrin enters intestinal epithelial Caco-2 cells by fluid-phase endocytosis
    • Fenyvesi, F., Reti-Nagy, K., Bacso, Z., Gutay-Toth, Z., Malanga, M., Fenyvesi, E., et al. (2014). Fluorescently labeled methyl-beta-cyclodextrin enters intestinal epithelial Caco-2 cells by fluid-phase endocytosis. PLoS ONE 9:e84856. doi: 10.1371/journal.pone.0084856
    • (2014) PLoS ONE , vol.9
    • Fenyvesi, F.1    Reti-Nagy, K.2    Bacso, Z.3    Gutay-Toth, Z.4    Malanga, M.5    Fenyvesi, E.6
  • 16
    • 0031039024 scopus 로고    scopus 로고
    • Direct regulation of the Akt proto-oncogene product by phosphatidyl-3
    • Franke, T. F., Kaplan, D. R., Cantley, L. C., and Toker, A. (1997). Direct regulation of the Akt proto-oncogene product by phosphatidyl-3,4-bisphosphate. Science 275, 665-668. doi: 10.1126/science.275.5300.665
    • (1997) 4-bisphosphate. Science , vol.275 , pp. 665-668
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3    Toker, A.4
  • 17
    • 84882318208 scopus 로고    scopus 로고
    • Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation
    • Fujii, M., Kawai, K., Egami, Y., and Araki, N. (2013). Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation. Sci. Rep. 3, 2385. doi: 10.1038/srep02385
    • (2013) Sci. Rep. , vol.3 , pp. 2385
    • Fujii, M.1    Kawai, K.2    Egami, Y.3    Araki, N.4
  • 18
    • 33947603008 scopus 로고    scopus 로고
    • Protein kinase C and other diacylglycerol effectors in cancer
    • Griner, E. M., and Kazanietz, M. G. (2007). Protein kinase C and other diacylglycerol effectors in cancer. Nat. Rev. Cancer 7, 281-294. doi: 10.1038/nrc2110
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 281-294
    • Griner, E.M.1    Kazanietz, M.G.2
  • 19
    • 0037542854 scopus 로고    scopus 로고
    • Ras proteins: different signals from different locations
    • Hancock, J. F. (2003). Ras proteins: different signals from different locations. Nat. Rev. Mol. Cell Biol. 4, 373-384. doi: 10.1038/nrm1105
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 373-384
    • Hancock, J.F.1
  • 20
    • 84859527579 scopus 로고    scopus 로고
    • Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner
    • Haspot, F., Lavault, A., Sinzger, C., Laib Sampaio, K., Stierhof, Y. D., Pilet, P., et al. (2012). Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner. PLoS ONE 7:e34795. doi: 10.1371/journal.pone.0034795
    • (2012) PLoS ONE , vol.7
    • Haspot, F.1    Lavault, A.2    Sinzger, C.3    Laib Sampaio, K.4    Stierhof, Y.D.5    Pilet, P.6
  • 21
    • 77954615408 scopus 로고    scopus 로고
    • MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo
    • Hirai, H., Sootome, H., Nakatsuru, Y., Miyama, K., Taguchi, S., Tsujioka, K., et al. (2010). MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo. Mol. Cancer Ther. 9, 1956-1967. doi: 10.1158/1535-7163.MCT-09-1012
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 1956-1967
    • Hirai, H.1    Sootome, H.2    Nakatsuru, Y.3    Miyama, K.4    Taguchi, S.5    Tsujioka, K.6
  • 22
    • 0036924067 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer-based stoichiometry in living cells
    • Hoppe, A., Christensen, K., and Swanson, J. A. (2002). Fluorescence resonance energy transfer-based stoichiometry in living cells. Biophys. J. 83, 3652-3664. doi: 10.1016/S0006-3495(02)75365-4
    • (2002) Biophys. J. , vol.83 , pp. 3652-3664
    • Hoppe, A.1    Christensen, K.2    Swanson, J.A.3
  • 23
    • 3342938063 scopus 로고    scopus 로고
    • Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis
    • Hoppe, A. D., and Swanson, J. A. (2004). Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis. Mol. Biol. Cell 15, 3509-3519. doi: 10.1091/mbc.E03-11-0847
    • (2004) Mol. Biol. Cell , vol.15 , pp. 3509-3519
    • Hoppe, A.D.1    Swanson, J.A.2
  • 24
    • 84873657250 scopus 로고    scopus 로고
    • Mammalian phospholipase C
    • Kadamur, G., and Ross, E. M. (2013). Mammalian phospholipase C. Annu. Rev. Physiol. 75, 127-154. doi: 10.1146/annurev-physiol-030212-183750
    • (2013) Annu. Rev. Physiol. , vol.75 , pp. 127-154
    • Kadamur, G.1    Ross, E.M.2
  • 25
    • 34347375817 scopus 로고    scopus 로고
    • Differential association of phosphatidylinositol 3-kinase, SHIP-1, and PTEN with forming phagosomes
    • Kamen, L. A., Levinsohn, J., and Swanson, J. A. (2007). Differential association of phosphatidylinositol 3-kinase, SHIP-1, and PTEN with forming phagosomes. Mol. Biol. Cell 18, 2463-2472. doi: 10.1091/mbc.E07-01-0061
    • (2007) Mol. Biol. Cell , vol.18 , pp. 2463-2472
    • Kamen, L.A.1    Levinsohn, J.2    Swanson, J.A.3
  • 26
    • 84896503356 scopus 로고    scopus 로고
    • Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis
    • Maekawa, M., Terasaka, S., Mochizuki, Y., Kawai, K., Ikeda, Y., Araki, N., et al. (2014). Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis. Proc. Natl. Acad. Sci. U.S.A. 111, E978-E987. doi: 10.1073/pnas.1311029111
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , pp. E978-E987
    • Maekawa, M.1    Terasaka, S.2    Mochizuki, Y.3    Kawai, K.4    Ikeda, Y.5    Araki, N.6
  • 27
    • 84856385380 scopus 로고    scopus 로고
    • Rottlerin and cancer: novel evidence and mechanisms
    • Maioli, E., Torricelli, C., and Valacchi, G. (2012). Rottlerin and cancer: novel evidence and mechanisms. ScientificWorldJournal 2012:350826. doi: 10.1100/2012/350826
    • (2012) ScientificWorldJournal , pp. 350826
    • Maioli, E.1    Torricelli, C.2    Valacchi, G.3
  • 28
    • 65449120034 scopus 로고    scopus 로고
    • Virus entry by macropinocytosis
    • Mercer, J., and Helenius, A. (2009). Virus entry by macropinocytosis. Nat. Cell Biol. 11, 510-520. doi: 10.1038/ncb0509-510
    • (2009) Nat. Cell Biol. , vol.11 , pp. 510-520
    • Mercer, J.1    Helenius, A.2
  • 29
    • 41649085148 scopus 로고    scopus 로고
    • A unique platform for H-Ras signaling involving clathrin-independent endocytosis
    • Porat-Shliom, N., Kloog, Y., and Donaldson, J. G. (2008). A unique platform for H-Ras signaling involving clathrin-independent endocytosis. Mol. Biol. Cell 19, 765-775. doi: 10.1091/mbc.E07-08-0841
    • (2008) Mol. Biol. Cell , vol.19 , pp. 765-775
    • Porat-Shliom, N.1    Kloog, Y.2    Donaldson, J.G.3
  • 30
    • 0024394044 scopus 로고
    • Macrophage colony stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages
    • Racoosin, E. L., and Swanson, J. A. (1989). Macrophage colony stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages. J. Exp. Med. 170, 1635-1648. doi: 10.1084/jem.170.5.1635
    • (1989) J. Exp. Med. , vol.170 , pp. 1635-1648
    • Racoosin, E.L.1    Swanson, J.A.2
  • 31
    • 0026776006 scopus 로고
    • M-CSF-induced macropinocytosis increases solute endocytosis but not receptor-mediated endocytosis in mouse macrophages
    • Racoosin, E. L., and Swanson, J. A. (1992). M-CSF-induced macropinocytosis increases solute endocytosis but not receptor-mediated endocytosis in mouse macrophages. J. Cell Sci. 102, 867-880.
    • (1992) J. Cell Sci. , vol.102 , pp. 867-880
    • Racoosin, E.L.1    Swanson, J.A.2
  • 32
    • 0027278232 scopus 로고
    • Macropinosome maturation and fusion with tubular lysosomes in macrophages
    • Racoosin, E. L., and Swanson, J. A. (1993). Macropinosome maturation and fusion with tubular lysosomes in macrophages. J. Cell Biol. 121, 1011-1020. doi: 10.1083/jcb.121.5.1011
    • (1993) J. Cell Biol. , vol.121 , pp. 1011-1020
    • Racoosin, E.L.1    Swanson, J.A.2
  • 33
    • 65349165676 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus utilizes an actin polymerization-dependent macropinocytic pathway to enter human dermal microvascular endothelial and human umbilical vein endothelial cells
    • Raghu, H., Sharma-Walia, N., Veettil, M. V., Sadagopan, S., and Chandran, B. (2009). Kaposi's sarcoma-associated herpesvirus utilizes an actin polymerization-dependent macropinocytic pathway to enter human dermal microvascular endothelial and human umbilical vein endothelial cells. J. Virol. 83, 4895-4911. doi: 10.1128/JVI.02498-08
    • (2009) J. Virol. , vol.83 , pp. 4895-4911
    • Raghu, H.1    Sharma-Walia, N.2    Veettil, M.V.3    Sadagopan, S.4    Chandran, B.5
  • 35
    • 0035168176 scopus 로고    scopus 로고
    • Sequential activities of phosphoinositide 3-kinase PKB/Akt, and Rab7 during macropinosome formation in Dictyostelium
    • Rupper, A., Lee, K., Knecht, D., and Cardelli, J. (2001). Sequential activities of phosphoinositide 3-kinase PKB/Akt, and Rab7 during macropinosome formation in Dictyostelium. Mol. Biol. Cell 12, 2813-2824. doi: 10.1091/mbc.12.9.2813
    • (2001) Mol. Biol. Cell , vol.12 , pp. 2813-2824
    • Rupper, A.1    Lee, K.2    Knecht, D.3    Cardelli, J.4
  • 36
    • 77954072416 scopus 로고    scopus 로고
    • A differential role for macropinocytosis in mediating entry of the two forms of vaccinia virus into dendritic cells
    • Sandgren, K. J., Wilkinson, J., Miranda-Saksena, M., McInerney, G. M., Byth-Wilson, K., Robinson, P. J., et al. (2010). A differential role for macropinocytosis in mediating entry of the two forms of vaccinia virus into dendritic cells. PLoS Pathog. 6:e1000866. doi: 10.1371/journal.ppat.1000866
    • (2010) PLoS Pathog , vol.6
    • Sandgren, K.J.1    Wilkinson, J.2    Miranda-Saksena, M.3    McInerney, G.M.4    Byth-Wilson, K.5    Robinson, P.J.6
  • 37
    • 28244451949 scopus 로고    scopus 로고
    • Selective inhibition by rottlerin of macropinocytosis in monocyte-derived dendritic cells
    • Sarkar, K., Kruhlak, M. J., Erlandsen, S. L., and Shaw, S. (2005). Selective inhibition by rottlerin of macropinocytosis in monocyte-derived dendritic cells. Immunology 116, 513-524. doi: 10.1111/j.1365-2567.2005.02253.x
    • (2005) Immunology , vol.116 , pp. 513-524
    • Sarkar, K.1    Kruhlak, M.J.2    Erlandsen, S.L.3    Shaw, S.4
  • 38
    • 12244303848 scopus 로고    scopus 로고
    • Ratiometric fluorescence microscopy
    • eds P. Sansonetti and A. Zychlinsky (New York NY: Academic Press)
    • Swanson, J. A. (2002). "Ratiometric fluorescence microscopy," in Molecular Cellular Biology, eds P. Sansonetti and A. Zychlinsky (New York, NY: Academic Press), 1-18.
    • (2002) Molecular Cellular Biology , pp. 1-18
    • Swanson, J.A.1
  • 39
    • 47749107873 scopus 로고    scopus 로고
    • Shaping cups into phagosomes and macropinosomes
    • Swanson, J. A. (2008). Shaping cups into phagosomes and macropinosomes. Nat. Rev. Mol. Cell Biol. 9, 639-649. doi: 10.1038/nrm2447
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 639-649
    • Swanson, J.A.1
  • 40
    • 84896007611 scopus 로고    scopus 로고
    • Overexpression of atypical protein kinase C in HeLa cells facilitates macropinocytosis via Src activation
    • Tisdale, E. J., Shisheva, A., and Artalejo, C. R. (2014). Overexpression of atypical protein kinase C in HeLa cells facilitates macropinocytosis via Src activation. Cell Signal. 26, 1235-1242. doi: 10.1016/j.cellsig.2014.02.014
    • (2014) Cell Signal , vol.26 , pp. 1235-1242
    • Tisdale, E.J.1    Shisheva, A.2    Artalejo, C.R.3
  • 41
    • 84964891885 scopus 로고    scopus 로고
    • A growth factor signaling cascade confined to circular ruffles in macrophages
    • Welliver, T. P., and Swanson, J. A. (2012). A growth factor signaling cascade confined to circular ruffles in macrophages. Biol. Open 1, 754-760. doi: 10.1242/bio.20121784
    • (2012) Biol. Open , vol.1 , pp. 754-760
    • Welliver, T.P.1    Swanson, J.A.2
  • 43
    • 80052736325 scopus 로고    scopus 로고
    • Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway
    • Yamamoto, K., Seki, T., Yamamoto, H., Adachi, N., Tanaka, S., Hide, I., et al. (2014). Deregulation of the actin cytoskeleton and macropinocytosis in response to phorbol ester by the mutant protein kinase C gamma that causes spinocerebellar ataxia type 14. Front. Physiol. 5:126. doi: 10.3389/fphys.2014.00126
    • (2011) J. Biol. Chem. , vol.286 , pp. 32651-32660
    • Yoshida, S.1    Hong, S.2    Suzuki, T.3    Nada, S.4    Mannan, A.M.5    Wang, J.6
  • 44
    • 70350349921 scopus 로고    scopus 로고
    • Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages
    • Yoshida, S., Hong, S., Suzuki, T., Nada, S., Mannan, A. M., Wang, J., et al. (2011). Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway. J. Biol. Chem. 286, 32651-32660. doi: 10.1074/jbc.M111.238014
    • (2009) J. Cell Sci. , vol.122 , pp. 3250-3261
    • Yoshida, S.1    Hoppe, A.D.2    Araki, N.3    Swanson, J.A.4
  • 45
    • 70350349921 scopus 로고    scopus 로고
    • Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages
    • Yoshida, S., Hoppe, A. D., Araki, N., and Swanson, J. A. (2009). Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages. J. Cell Sci. 122, 3250-3261. doi: 10.1242/jcs.053207
    • (2009) J. Cell Sci , vol.122 , pp. 3250-3261
    • Yoshida, S.1    Hoppe, A.D.2    Araki, N.3    Swanson, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.