Bemiparin versus enoxaparin as thromboprophylaxis following vaginal and abdominal deliveries: A prospective clinical trial

BMC Pregnancy and Childbirth

Volumn 15, Issue 1, 2015, Pages

  Alalaf, Shahla K ^a   Jawad, Rojan K ^a   Muhammad, Parez R ^a   Ali, Mahabad S ^b   Al Tawil, Namir G ^a  

^a HAWLER MEDICAL UNIVERSITY   (Iraq)

^b Hawler Ministry of Health Directorate of Health Kurdistan Region   (Iraq)

Author keywords

Bemiparin; Enoxaparin; Low molecular weight heparin; Postpartum thromboprophylaxis

Indexed keywords

BEMIPARIN; ENOXAPARIN; ANTICOAGULANT AGENT; LOW MOLECULAR WEIGHT HEPARIN;

ADULT; ARTICLE; CESAREAN SECTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG COST; ECCHYMOSIS; EMERGENCY SURGERY; FEMALE; HEMATOMA; HUMAN; INJECTION SITE PAIN; IRAQ; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PROSPECTIVE STUDY; PUERPERIUM; SKIN ALLERGY; SKIN BRUISING; SKIN PRURITUS; SPINAL ANESTHESIA; TEACHING HOSPITAL; THROMBOSIS PREVENTION; URTICARIA; VAGINAL DELIVERY; VENOUS THROMBOEMBOLISM; WOUND DEHISCENCE; WOUND HEMATOMA; CHEMICALLY INDUCED; CLINICAL TRIAL; DRUG EFFECTS; INCIDENCE; NATURAL CHILDBIRTH; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREVALENCE; RISK FACTOR;

ADULT; ANTICOAGULANTS; CESAREAN SECTION; ENOXAPARIN; FEMALE; HEMATOMA; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; INCIDENCE; IRAQ; NATURAL CHILDBIRTH; POSTPARTUM PERIOD; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREVALENCE; PROSPECTIVE STUDIES; RISK FACTORS; SURGICAL WOUND DEHISCENCE; VENOUS THROMBOEMBOLISM;

EID: 84926324984     PISSN: None     EISSN: 14712393     Source Type: Journal    
DOI: 10.1186/s12884-015-0515-2     Document Type: Article

References (25)

1. Rosendaal FR. Risk factors for venous thrombotic disease. Thromb Haemost. 1999;82:610-9.
2. James AH, Tapson VF, Goldhaber SZ. Thrombosis during pregnancy and the postpartum period. Am J Obstet Gynecol. 2005;193:216-9.
3. Wu P, Poole TC, Pickett JA, Bhat A, Lees CC. Current obstetric guidelines on thromboprophylaxis in the United Kingdom: evidence based medicine? Eur J Obstet Gynecol Reprod Biol. 2013;168:7-11.
4. Bates SM, Greer IA, Pabinger I, Sofaer S, Hirsh J, American College of Chest Physicians. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133:844S-86.
5. Bain E, Wilson A, Tooher R, Gates S, Davis LJ, Middleton P. Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period. Cochrane Database Syst Rev. 2014;2:CD001689.
6. Royal College of Obstetricians and Gynaecologists. Reducing the risk of thrombosis and embolism during pregnancy and the puerperium 2009 (Green-top Guideline No. 37).
7. Hill J, Treasure T. Reducing the risk of venous thromboembolism in patients admitted to hospital: summary of NICE guidance. BMJ. 2010;340:c95.
8. Cosmi B, Palareti G. Old and new heparins. Thromb Res. 2012;129:388-91.
9. Lucas DN, Yentis SM, Kinsella SM, et al. Urgency of caesarean section: a new classification. J R Soc Med. 2000;93:346-50.
10. Greer IA. Thrombosis in pregnancy: maternal and fetal issues. Lancet. 1999;353:1258-65.
11. Dizon-Townson DS, Nelson LM, Jang H, Varner MW, Ward K. The incidence of the factor V Leiden mutation in an obstetric population and its relationship to deep vein thrombosis. Am J Obstet Gynecol. 1997;176:883-6.
12. Greer IA, Nelson-Piercy C. Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy. Blood. 2005;106:401-7.
13. Piazza G, Goldhaber SZ. Acute pulmonary embolism: part II: treatment and prophylaxis. Circulation. 2006;114:e42-7.
14. Heit JA, Silverstein MD, Mohr DN, Petterson TM, O'Fallon WM, Melton 3rd LJ. Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based, cohort study. Arch Intern Med. 1999;159:445-53.
15. Ferres MA, Olivarez SA, Trinh V, Davidson C, Sangi-Haghpeykar H, Aagaard-Tillery KM. Rate of wound complications with enoxaparin use among women at high risk for postpartum thrombosis. Obstet Gynecol. 2011;117:119-24.
16. Tooher R, Gates S, Dowswell T, Davis LJ. Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period. Cochrane Database Syst Rev. 2010;5:CD001689.
17. Connolly T. Thromboembolism prophylaxis and cesarean section: a survey of general obstetricians. South Med J. 2003;96:146-8.
18. Orme ML, Lewis PJ, de Swiet M, et al. NICE 2004 National Collaborating Centre for Women's and Children's Health, Commissioned by NICE. Caesarean section. London: RCOG Press; 2004.
19. Cruz M, Fernández-Alonso AM, Rodríguez I, et al. Postcesarean thromboprophylaxis with two different regimens of bemiparin. Obstet Gynecol Int. 2011;2011:548327.
20. Blondon M, Perrier A, Nendaz M, Righini M, et al. Thromboprophylaxis with low-molecular-weight heparin after cesarean delivery. Thromb Haemost. 2010;103:129-37.
21. Segal S, Sadovsky E, Weinsten D, Polishk WZ. Prevention of postpartum venous thrombosis with low doses of heparin. Eur J Obstet Gynecol Reprod Biol. 1975;5:273-6.
22. O'Connor DJ, Scher LA, Gargiulo 3rd NJ, Jang J, Suggs WD, Lipsitz EC. Incidence and characteristics of venous thromboembolic disease during pregnancy and the postnatal period: acontemporary series. Ann Vasc Surg. 2011;25:9-14.
23. Heit JA, Kobbervig CE, James AH, Petterson TM, Bailey KR, Melton 3rd LJ. Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study. Ann Intern Med. 2005;143:697-706.
24. Barbour LA, Pickard J. Controversies in thromboembolic disease during pregnancy: a critical review. Obstet Gynecol. 1995;86:621-33.
25. Rutherford S, Montoro M, McGehee W, Strong T. Thromboembolic disease associated with pregnancy: An 11-year review. Am J Obstet Gynecol. 1991;164:286 [abstract].