Histone demethylase LSD2 Acts as an E3Ubiquitin ligase and inhibits cancer cell growth through promoting proteasomal degradation of OGT

Molecular Cell

Volumn 58, Issue 1, 2015, Pages 47-59

  Yang, Yi ^a   Yin, Xiaotong ^a   Yang, Huirong ^a   Xu, Yanhui ^a,b,c  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^b FUDAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; HISTONE DEMETHYLASE; HISTONE H3; HISTONE LYSINE DEMETHYLASE 2; O LINKED BETA N ACETYLGLUCOSAMINE TRANSFERASE; TRANSFERASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; HISTONE; LYSINE (K)-SPECIFIC DEMETHYLASE 1B, HUMAN; N ACETYLGLUCOSAMINYLTRANSFERASE; O-GLCNAC TRANSFERASE; PROTEASOME; UBIQUITIN PROTEIN LIGASE;

A549 CELL LINE; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; COLONY FORMATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE TARGETING; HUMAN; HUMAN CELL; PROTEIN DEPLETION; UBIQUITINATION; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HISTONE DEMETHYLASES; HISTONES; HUMANS; N-ACETYLGLUCOSAMINYLTRANSFERASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84926215563     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.01.038     Document Type: Article

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