Intestinal decontamination of multidrug-resistant Klebsiella pneumoniae after recurrent infections in an immunocompromised host

Diagnostic Microbiology and Infectious Disease

Volumn 80, Issue 1, 2014, Pages 87-89

  Kronman, Matthew P ^a,b,c   Zerr, Danielle M ^a,b,c   Qin, Xuan ^b,d   Englund, Janet ^a,b,c   Cornell, Cathy ^b   Sanders, Jean E ^a,e   Myers, Jeffrey ^c   Rayar, Jaipreet ^c   Berry, Jessica E ^c   Adler, Amanda L ^c   Weissman, Scott J ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^d SEATTLE CHILDREN S HOSPITAL   (United States)

^e USA   (United States)

Author keywords

Hematopoietic cell transplantation; Intestinal decontamination; Klebsiella pneumoniae; Pediatrics; Resistance

Indexed keywords

AMIKACIN; CARBAPENEM; COLISTIN; IMIPENEM; MEROPENEM; TIGECYCLINE; ANTIINFECTIVE AGENT;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BACTERIAL ARTHRITIS; BACTERIAL COLONIZATION; BACTERIUM CULTURE; BACTERIUM ISOLATE; CARBAPENEM NEGATIVE ESCHERICHIA COLI; CARBAPENEM RESISTANT ESCHERICHIA COLI; CARBAPENEM SUSCEPTIBLE KLEBSIELLA PNEUMONIAE; CARBAPENEM SUSCEPTIBLE KLEBSIELLA PNEUMONIAE BACTEREMIA; CASE REPORT; CHRONIC OSTEOMYELITIS; ESCHERICHIA COLI; FEBRILE NEUTROPENIA; FECES CULTURE; FOLLOW UP; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOCOMPROMISED PATIENT; INFECTION; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; KNEE PAIN; MALE; MOLECULAR TYPING; MULTIDRUG RESISTANT KLEBSIELLA PNEUMONIAE; MULTILOCUS SEQUENCE TYPING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RECIPIENT; RECURRENT INFECTION; RECURRENT MULTIDRUG RESISTANT KLEBSIELLA PNEUMONIAE INFECTION; SUPERFICIAL PARASPINOUS INFECTION; TOTAL KNEE REPLACEMENT; URINARY TRACT INFECTION; YOUNG ADULT; CLASSIFICATION; DRUG EFFECTS; FECES; GENETICS; GRAFT RECIPIENT; KLEBSIELLA INFECTIONS; MICROBIOLOGY; MULTIDRUG RESISTANCE; RECURRENT DISEASE; SKIN DISEASES, BACTERIAL;

ADULT; ANTI-BACTERIAL AGENTS; BACTEREMIA; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FECES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOCOMPROMISED HOST; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; RECURRENCE; SKIN DISEASES, BACTERIAL; TRANSPLANT RECIPIENTS; YOUNG ADULT;

EID: 84926200495     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2014.06.006     Document Type: Article

References (16)

1. Centers for Disease Control and Prevention (CDC) Vital signs: carbapenem-resistant Enterobacteriaceae. MMWR Morb Mortal Wkly Rep 2013, 62:165-170.
2. Borer A., Saidel-Odes L., Eskira S., Nativ R., Riesenberg K., Livshiz-Riven I., et al. Risk factors for developing clinical infection with carbapenem-resistant Klebsiella pneumoniae in hospital patients initially only colonized with carbapenem-resistant K pneumoniae. Am J Infect Control 2012, 40:421-425.
3. Brisse S., Fevre C., Passet V., Issenhuth-Jeanjean S., Tournebize R., Diancourt L., et al. Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization. PLoS One 2009, 4(3):e4982. Epub 2009 Mar 25. 10.1371/journal.pone.0004982.
4. Calfee D., Jenkins S.G. Use of active surveillance cultures to detect asymptomatic colonization with carbapenem-resistant Klebsiella pneumoniae in intensive care unit patients. Infect Control Hosp Epidemiol 2008, 29:966-968.
5. De Lastours V., Cambau E., Guillard T., Marcade G., Chau F., Fantin B. Diversity of individual dynamic patterns of emergence of resistance to quinolones in Escherichia coli from the fecal flora of healthy volunteers exposed to ciprofloxacin. J Infect Dis 2012, 206:1399-1406.
6. Friedman-Moraco R.J., Mehta A.K., Lyon G.M., Kraft C.S. Fecal microbiota transplantation for refractory Clostridium difficile colitis in solid organ transplant recipients. Am J Transplant 2014, 14:477-480.
7. Gijon D., Curiao T., Baquero F., Coque T.M., Canton R. Fecal carriage of carbapenemase-producing Enterobacteriaceae: a hidden reservoir in hospitalized and nonhospitalized patients. J Clin Microbiol 2012, 50:1558-1563.
8. Han J.H., Kasahara K., Edelstein P.H., Bilker W.B., Lautenbach E. Risk factors for infection or colonization with CTX-M extended-spectrum-beta-lactamase-positive Escherichia coli. Antimicrob Agents Chemother 2012, 56:5575-5580.
9. Humphries R.M., Kelesidis T., Dien Bard J., Ward K.W., Bhattacharya D., Lewinski M.A. Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin. J Med Microbiol 2010, 59:1383-1386.
10. Oostdijk E.A., De Smet A.M., Kesecioglu J., Bonten M.J. Decontamination of cephalosporin-resistant Enterobacteriaceae during selective digestive tract decontamination in intensive care units. J Antimicrob Chemother 2012, 67:2250-2253.
11. Patel G., Huprikar S., Factor S.H., Jenkins S.G., Calfee D.P. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 2008, 29:1099-1106.
12. Saidel-Odes L., Polachek H., Peled N., Riesenberg K., Schlaeffer F., Trabelsi Y., et al. A randomized, double-blind, placebo-controlled trial of selective digestive decontamination using oral gentamicin and oral polymyxin E for eradication of carbapenem-resistant Klebsiella pneumoniae carriage. Infect Control Hosp Epidemiol 2012, 33:14-19.
13. Tenover F.C., Arbeit R.D., Goering R.V., Mickelsen P.A., Murray B.E., Persing D.H., et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995, 33:2233-2239.
14. Tzouvelekis L.S., Markogiannakis A., Psichogiou M., Tassios P.T., Daikos G.L. Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions. Clin Microbiol Rev 2012, 25:682-707.
15. Van Nood E., Vrieze A., Nieuwdorp M., Fuentes S., Zoetendal E.G., De Vos W.M., et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med 2013, 368:407-415.
16. Zuckerman T., Benyamini N., Sprecher H., Fineman R., Finkelstein R., Rowe J.M., et al. SCT in patients with carbapenem resistant Klebsiella pneumoniae: a single center experience with oral gentamicin for the eradication of carrier state. Bone Marrow Transplant 2011, 46:1226-1230.