Impact of treatment time and dose escalation on local control in locally advanced cervical cancer treated by chemoradiation and image-guided pulsed-dose rate adaptive brachytherapy

Radiotherapy and Oncology

Volumn 114, Issue 2, 2015, Pages 257-263

  Mazeron, Renaud ^a   Castelnau Marchand, Pauline ^a   Dumas, Isabelle ^a   Del Campo, Eleonor Rivin ^a   Kom, Léopold Kamsu ^a   Martinetti, Florent ^a   Farha, George ^a   Tailleur, Anne ^a   Morice, Philippe ^a   Chargari, Cyrus ^a   Lefkopoulos, Dimitri ^a   Haie Meder, Christine ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Cervical cancer; D90; Dose effect correlation; Image guided adaptive brachytherapy; Local control; Treatment time

Indexed keywords

CARBOPLATIN; CISPLATIN;

ADULT; ADVANCED CANCER; ARTICLE; BRACHYTHERAPY; CANCER CONTROL; CANCER LOCALIZATION; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SIZE; CANCER STAGING; CHEMORADIOTHERAPY; CONTROLLED STUDY; DOSE RESPONSE; EXTERNAL BEAM RADIOTHERAPY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MIDDLE AGED; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE ESCALATION; RADIATION RESPONSE; RADIOTHERAPY PLANNING SYSTEM; RISK FACTOR; SQUAMOUS CELL CARCINOMA; TIME TO TREATMENT; TREATMENT DURATION; TREATMENT RESPONSE; UTERINE CERVIX CARCINOMA; COMPUTER ASSISTED TOMOGRAPHY; NEOPLASM RECURRENCE, LOCAL; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; TREATMENT OUTCOME; TUMOR RECURRENCE; UTERINE CERVICAL NEOPLASMS;

BRACHYTHERAPY; CARBOPLATIN; CHEMORADIOTHERAPY; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROPORTIONAL HAZARDS MODELS; RADIOTHERAPY DOSAGE; RETROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS;

EID: 84926200004     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2014.11.045     Document Type: Article

References (22)

1. K. Han, M. Milosevic, A. Fyles, M. Pintilie, and A.N. Viswanathan Trends in the utilization of brachytherapy in cervical cancer in the United States Int J Radiat Oncol Biol Phys 87 2013 111 119
2. Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data from 18 randomized trials J Clin Oncol 26 2008 5802 5812
3. R. Potter, P. Georg, J.C. Dimopoulos, M. Grimm, D. Berger, and N. Nesvacil Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer Radiother Oncol 100 2011 116 123
4. R. Mazeron, J. Gilmore, I. Dumas, J. Champoudry, J. Goulart, and B. Vanneste Adaptive 3D image-guided brachytherapy: a strong argument in the debate on systematic radical hysterectomy for locally advanced cervical cancer Oncologist 18 2013 415 422
5. J.C. Dimopoulos, R. Potter, S. Lang, E. Fidarova, P. Georg, and W. Dorr Dose-effect relationship for local control of cervical cancer by magnetic resonance image-guided brachytherapy Radiother Oncol 93 2009 311 315
6. N. Magne, C. Chargari, N. SanFilippo, T. Messai, A. Gerbaulet, and C. Haie-Meder Technical aspects and perspectives of the vaginal mold applicator for brachytherapy of gynecologic malignancies Brachytherapy 9 2009 274 277
7. P. Morice, P. Rouanet, A. Rey, P. Romestaing, G. Houvenaeghel, and J.C. Boulanger Results of the GYNECO 02 study, an FNCLCC phase III trial comparing hysterectomy with no hysterectomy in patients with a (clinical and radiological) complete response after chemoradiation therapy for stage IB2 or II cervical cancer Oncologist 17 2012 64 71
8. T.P. Hellebust, C. Kirisits, D. Berger, J. Perez-Calatayud, M. De Brabandere, and A. De Leeuw Recommendations from GYNAECOLOGICAL (GYN) GEC-ESTRO Working Group: considerations and pitfalls in commissioning and applicator reconstruction in 3D image-based treatment planning of cervix cancer brachytherapy Radiother Oncol 96 2010 153 160
9. C. Haie-Meder, R. Potter, E. Van Limbergen, E. Briot, M. De Brabandere, and J. Dimopoulos Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV Radiother Oncol 74 2005 235 245
10. R. Potter, C. Haie-Meder, E. Van Limbergen, I. Barillot, M. De Brabandere, and J. Dimopoulos Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology Radiother Oncol 78 2006 67 77
11. A. Fyles, T.J. Keane, M. Barton, and J. Simm The effect of treatment duration in the local control of cervix cancer Radiother Oncol 25 1992 273 279
12. T. Girinsky, A. Rey, B. Roche, C. Haie, A. Gerbaulet, and H. Randrianarivello Overall treatment time in advanced cervical carcinomas: a critical parameter in treatment outcome Int J Radiat Oncol Biol Phys 27 1993 1051 1056
13. R.M. Lanciano, T.F. Pajak, K. Martz, and G.E. Hanks The influence of treatment time on outcome for squamous cell cancer of the uterine cervix treated with radiation: a patterns-of-care study Int J Radiat Oncol Biol Phys 25 1993 391 397
14. C.A. Perez, P.W. Grigsby, H. Castro-Vita, and M.A. Lockett Carcinoma of the uterine cervix. I. Impact of prolongation of overall treatment time and timing of brachytherapy on outcome of radiation therapy Int J Radiat Oncol Biol Phys 32 1995 1275 1288
15. P.J. Eifel, and H.D. Thames Has the influence of treatment duration on local control of carcinoma of the cervix been defined? Int J Radiat Oncol Biol Phys 32 1995 1527 1529
16. D.G. Petereit, J.N. Sarkaria, R. Chappell, J.F. Fowler, T.J. Hartmann, and T.J. Kinsella The adverse effect of treatment prolongation in cervical carcinoma Int J Radiat Oncol Biol Phys 32 1995 1301 1307
17. N. Shaverdian, V. Gondi, K.L. Sklenar, E.F. Dunn, D.G. Petereit, and M.R. Straub Effects of treatment duration during concomitant chemoradiation therapy for cervical cancer Int J Radiat Oncol Biol Phys 86 2013 562 568
18. C. Chargari, N. Magné, I. Dumas, T. Messai, L. Vicenzi, and N. Gillion Physics contribution and clinical outcoles with 3D-MRI-pulsed-dose-rate intracavitary brachytherapy in cervical cancer patients Int J Radiat Oncol Biol Phys 74 2009 133 139
19. C.A. Perez, S. Fox, M.A. Lockett, P.W. Grigsby, H.M. Camel, and A. Galakatos Impact of dose in outcome of irradiation alone in carcinoma of the uterine cervix: analysis of two different methods Int J Radiat Oncol Biol Phys 21 1991 885 898
20. C.N. Nomden, A.A. de Leeuw, J.M. Roesink, R.J. Tersteeg, M.A. Moerland, and P.O. Witteveen Clinical outcome and dosimetric parameters of chemo-radiation including MRI guided adaptive brachytherapy with tandem-ovoid applicators for cervical cancer patients: a single institution experience Radiother Oncol 107 2013 69 74
21. J.C. Dimopoulos, S. Lang, C. Kirisits, E.F. Fidarova, D. Berger, and P. Georg Dose-volume histogram parameters and local tumor control in magnetic resonance image-guided cervical cancer brachytherapy Int J Radiat Oncol Biol Phys 75 2009 56 63
22. M.P. Schmid, C. Kirisits, N. Nesvacil, J.C. Dimopoulos, D. Berger, and R. Potter Local recurrences in cervical cancer patients in the setting of image-guided brachytherapy: a comparison of spatial dose distribution within a matched-pair analysis Radiother Oncol 100 2011 468 472