Poxvirus decapping enzymes enhance virulence by preventing the accumulation of dsRNA and the induction of innate antiviral responses

Cell Host and Microbe

Volumn 17, Issue 3, 2015, Pages 320-331

  Liu, Shin Wu ^a   Katsafanas, George C ^a   Liu, Ruikang ^a   Wyatt, Linda S ^a   Moss, Bernard ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; DOUBLE STRANDED RNA; INITIATION FACTOR 2ALPHA; PROTEIN KINASE R; RIBONUCLEASE L; RIBOSOME RNA; VIRUS ENZYME; INITIATION FACTOR 2; MRNA DECAPPING ENZYMES; RIBONUCLEASE; VIRAL PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; ENZYME ACTIVE SITE; HOST RANGE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MOUSE; NONHUMAN; POXVIRIDAE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RNA DEGRADATION; VACCINIA VIRUS; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; CELL LINE; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; VIRULENCE;

POXVIRIDAE; VACCINIA VIRUS;

2',5'-OLIGOADENYLATE SYNTHETASE; ANIMALS; CELL LINE; EIF-2 KINASE; ENDORIBONUCLEASES; EUKARYOTIC INITIATION FACTOR-2; HUMANS; IMMUNITY, INNATE; RNA, DOUBLE-STRANDED; VACCINIA VIRUS; VIRAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 84926153111     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2015.02.002     Document Type: Article

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