Expanded blood borne virus testing in a tuberculosis clinic. A cost and yield analysis

Journal of Infection

Volumn 70, Issue 4, 2015, Pages 317-323

  Sewell, J ^a   Capocci, S ^b   Johnson, J ^b   Solamalai, A ^b   Hopkins, S ^b   Cropley, I ^b   Webster, D P ^b   Lipman, M ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Hepatitis B virus; Hepatitis C virus; HIV infection; Tuberculosis; Tuberculosis management

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD BORNE VIRUS TESTING; DEMOGRAPHY; FEMALE; HEALTH CARE COST; HEPATITIS B; HEPATITIS C; HIV TEST; HOSPITAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; SERODIAGNOSIS; TUBERCULOSIS; UNITED KINGDOM; BLOODBORNE BACTERIUM; COST; ECONOMICS; HIV INFECTIONS; ISOLATION AND PURIFICATION; LABORATORY DIAGNOSIS; MASS SCREENING; MIDDLE AGED; PREVALENCE; RETROSPECTIVE STUDY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BLOOD-BORNE PATHOGENS; CLINICAL LABORATORY SERVICES; COSTS AND COST ANALYSIS; DEMOGRAPHY; FEMALE; HEPATITIS B; HEPATITIS C; HIV INFECTIONS; HUMANS; MALE; MASS SCREENING; MIDDLE AGED; PREVALENCE; RETROSPECTIVE STUDIES; TUBERCULOSIS; YOUNG ADULT;

EID: 84926132387     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2014.10.014     Document Type: Article

References (23)

1. Blasi F., Matteelli A. Indicator condition-guided HIV testing in Europe: a step forward to HIV control. Eur Respir J 2013, 42(3):572-575.
2. British HIV Association UK national guidelines for HIV testing 2008, London, URL:, [accessed Nov 2012]. http://www.bhiva.org/HIVTesting2008.aspx.
3. National Institute for Health and Clinical Excellence PH33 increasing the uptake of HIV testing among black Africans in England: guidance 2011, London, URL:, [accessed Jan 2013]. http://guidance.nice.org.uk/PH33/Guidance/pdf/English.
4. Ramachandran P., Fraser A., Agarwal K., Austin A., Brown A., Foster G.R., et al. UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic Hepatitis C infected patients. Aliment Pharmacol Ther 2012, 35(6):647-662.
5. Scaglione S.J., Lok A.S. Effectiveness of Hepatitis B treatment inclinical practice. Gastroenterology 2012, 142(6). 1360-1368.e1.
6. National Institute for Health and Care Excellence NICE public health guidance 43: Hepatitis B and C: ways to promote and offer testing to people at increased risk of infection 2012, London, URL:, [accessed Jan 2013]. http://publications.nice.org.uk/hepatitis-b-and-c-ways-to-promote-and-offer-testing-to-people-at-increased-risk-of-infection-ph43.
7. Uddin G., Shoeb D., Solaiman S., Marley R., Gore C., Ramsay M., et al. Prevalence of chronic viral hepatitis in people of South Asian ethnicity living in England: the prevalence cannot necessarily be predicted from the prevalence in the country of origin. J Viral Hepat 2010, 17(5):327-335.
8. Harris D.H., Ramsay D.M. Health Protection Agency: Hepatitis C in the UK 2012, London, URL:, [accessed Jan 2013]. http://www.hpa.org.uk/Publications/InfectiousDiseases/BloodBorneInfections/HepatitisCInTheUK/1207HepCintheUK2012/.
9. Selwyn P.A., Hartel D., Lewis V.A., Schoenbaum E.E., Vermund S.H., Klein R.S., et al. A prospective study of the risk of tuberculosis among intravenous drug users with human immunodeficiency virus infection. N Engl J Med 1989, 320(9):545.
10. Saukkonen J.J., Cohn D.L., Jasmer R.M., Schenker S., Jereb J.A., Nolan C.M., et al. An official ATS statement: hepatotoxicity of antituberculosis therapy. Am J Respir Crit Care Med 2006, 174(8):935-952.
11. Gardner A., Naureckas C., Beckwith C., Losikoff P., Martin C., Carter E.J. Experiences in implementation of routine human immunodeficiency virus testing in a US tuberculosis clinic. Int J Tuberc Lung Dis 2012, 16(9):1241-1246.
12. Tedder R.S., Rodger A.J., Fries L., Ijaz S., Thursz M., Rosenberg W., et al. The diversity and management of chronic Hepatitis B virus infections in the United Kingdom: a wake-up call. Clin Infect Dis 2013, 56(7):951-960.
13. Caley M., Fowler T., Greatrex S., Wood A. Differences in Hepatitis B infection rate between ethnic groups in antenatal women in Birmingham, United Kingdom, May 2004 to December 2008. Euro Surveill 2012, 17(30).
14. Sanders G.D., Bayoumi A.M., Sundaram V., Bilir S.P., Neukermans C.P., Rydzak C.E., et al. Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy. N Engl J Med 2005, 352(6):570-585.
15. Health Protection Agency HIV prevalence greatest in London boroughs but quality of care is high 2010, London, Retrieved October 2010 from:. http://www.hpa.org.uk/ProductsServices/LocalServices/London/LondonPressReleases/lond101126HIVprevalencegreatestinLondon/?
16. Moyer V.A. Screening for HIV: U.S. Preventive services task force recommendation statement. Ann Intern Med 2013, 159(1):51-60. on behalf of the U.S. Preventive Services Task Force.
17. Miller R., Lipman M. HIV pre-test discussion. BMJ 1996, 313(7050):130.
18. Veldhuijzen I.K., Toy M., Hahné S.J., De Wit G.A., Schalm S.W., de Man R.A., et al. Screening and early treatment of migrants for chronic Hepatitis B virus infection is cost-effective. Gastroenterology 2010, 138(2):522-530.
19. Miners A.H., Martin N.K., Ghosh A., Hickman M., Vickerman P. Assessing the cost-effectiveness of finding cases of hepatitis C infection in UK migrant populations and the value of further research. J Viral Hepat 2014, 21(9):616-623.
20. Beasley V.E., Anders R., Darmalingam M. British Thoracic Society Winter Meeting 2013 Abstract P94 Retrospective study to assess the background incidence of Hepatitis B and C in patients with tuberculosis and latent tuberculosis at Whipps Cross Hospital. Thorax 2013, 68(Suppl. 3):A117-A118.
21. Moyer V.A. Screening for hepatitis C virus infection in adults: U.S. Preventive services task force recommendation statement. Ann Intern Med 2013, 159(5):349-357. on behalf of the U.S. Preventive Services Task Force.
22. Ngo-Metzger Q., Ward J.W., Valdiserri R.O. Expanded hepatitis C virus screening recommendations promote opportunities for care and cure. Ann Intern Med 2013, 159(5):364-365.
23. Roy A., Anaraki S., Hardelid P., Catchpole M., Rodrigues L.C., Lipman M., et al. Universal HIV testing in London tuberculosis clinics: a cluster randomised controlled trial. Eur Respir J 2013, 41(3):627-634.