메뉴 건너뛰기




Volumn 24, Issue 5, 2014, Pages 468-474

Features and management of pyrexia with combined dabrafenib and trametinib in metastatic melanoma

Author keywords

BRAF inhibitor; Dabrafenib; Fever; Management; MEK inhibitor; Melanoma; Prophylaxis; Pyrexia; Toxicity; Trametinib

Indexed keywords

CORTICOSTEROID; DABRAFENIB; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PREDNISONE; TRAMETINIB; ANTINEOPLASTIC AGENT; IMIDAZOLE DERIVATIVE; OXIME; PYRIDONE DERIVATIVE; PYRIMIDINONE DERIVATIVE;

EID: 84926097366     PISSN: 09608931     EISSN: 14735636     Source Type: Journal    
DOI: 10.1097/CMR.0000000000000110     Document Type: Article
Times cited : (37)

References (17)
  • 2
    • 84864722943 scopus 로고    scopus 로고
    • NRAS mutation status is an independent prognostic factor in metastatic melanoma
    • Jakob JA, Bassett RL Jr, Ng CS, Curry JL, Joseph RW, Alvarado GC, et al. NRAS mutation status is an independent prognostic factor in metastatic melanoma. Cancer 2012;118:4014-4023.
    • (2012) Cancer , vol.118 , pp. 4014-4023
    • Jakob, J.A.1    Bassett, R.L.2    Ng, C.S.3    Curry, J.L.4    Joseph, R.W.5    Alvarado, G.C.6
  • 4
    • 84864285704 scopus 로고    scopus 로고
    • Dabrafenib in BRAF-mutated metastatic melanoma: A multicentre, openlabel, phase 3 randomised controlled trial
    • Hauschild A, Grob JJ, Demidov LV, Jouary T, Gutzmer R, Millward M, et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, openlabel, phase 3 randomised controlled trial. Lancet 2012;380:358-365.
    • (2012) Lancet , vol.380 , pp. 358-365
    • Hauschild, A.1    Grob, J.J.2    Demidov, L.V.3    Jouary, T.4    Gutzmer, R.5    Millward, M.6
  • 9
    • 84856485172 scopus 로고    scopus 로고
    • Phase I/II expansion cohort of BRAF inhibitor GSK2118436 +MEK inhibitor GSK1120212 in patients with BRAF mutant metastatic melanoma who progressed on a prior BRAF inhibitor
    • Flaherty KT, Infante JR, Falchook GS, Weber J, Daud A, Hamid O, et al. Phase I/II expansion cohort of BRAF inhibitor GSK2118436 +MEK inhibitor GSK1120212 in patients with BRAF mutant metastatic melanoma who progressed on a prior BRAF inhibitor. Pigment Cell Melanoma Res 2011;24:1022 (abstract LBA1021-1024).
    • (2011) Pigment Cell Melanoma Res , vol.24 , pp. 1022
    • Flaherty, K.T.1    Infante, J.R.2    Falchook, G.S.3    Weber, J.4    Daud, A.5    Hamid, O.6
  • 10
    • 84881611323 scopus 로고    scopus 로고
    • Effects of particle size, food, and capsule shell composition on the oral bioavailability of dabrafenib, a BRAF inhibitor, in patients with BRAF mutation-positive tumors
    • Ouellet D, Grossmann KF, Limentani G, Nebot N, Lan K, Knowles L, et al. Effects of particle size, food, and capsule shell composition on the oral bioavailability of dabrafenib, a BRAF inhibitor, in patients with BRAF mutation-positive tumors. J Pharm Sci 2013;102:3100-3109.
    • (2013) J Pharm Sci , vol.102 , pp. 3100-3109
    • Ouellet, D.1    Grossmann, K.F.2    Limentani, G.3    Nebot, N.4    Lan, K.5    Knowles, L.6
  • 12
    • 84861083983 scopus 로고    scopus 로고
    • Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial
    • Falchook GS, Long GV, Kurzrock R, Kim KB, Arkenau TH, Brown MP, et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet 2012;379:1893-1901.
    • (2012) Lancet , vol.379 , pp. 1893-1901
    • Falchook, G.S.1    Long, G.V.2    Kurzrock, R.3    Kim, K.B.4    Arkenau, T.H.5    Brown, M.P.6
  • 13
    • 84873728334 scopus 로고    scopus 로고
    • Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance
    • Das Thakur M, Salangsang F, Landman AS, Sellers WR, Pryer NK, Levesque MP, et al. Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance. Nature 2013;494:251-255.
    • (2013) Nature , vol.494 , pp. 251-255
    • Das Thakur, M.1    Salangsang, F.2    Landman, A.S.3    Sellers, W.R.4    Pryer, N.K.5    Levesque, M.P.6
  • 14
    • 84926120873 scopus 로고    scopus 로고
    • Efficacy, safety, and pharmacokinetics (PK) of the BRAF inhibitor dabrafenib (D) hydroxypropyl methylcellulose (HPMC) capsule formulation in combination with the MEK1/2 inhibitor trametinib (T) in patients (pts) with BRAF mutation-positive metastatic melanoma (MM) [abstract]
    • Schuchter LM, Kudchadkar RR, Gonzalez R, Lawrence DP, Sosman JA, Infante JR, et al. Efficacy, safety, and pharmacokinetics (PK) of the BRAF inhibitor dabrafenib (D) hydroxypropyl methylcellulose (HPMC) capsule formulation in combination with the MEK1/2 inhibitor trametinib (T) in patients (pts) with BRAF mutation-positive metastatic melanoma (MM) [abstract]. J Clin Oncol 2013;31:9066.
    • (2013) J Clin Oncol , vol.31 , pp. 9066
    • Schuchter, L.M.1    Kudchadkar, R.R.2    Gonzalez, R.3    Lawrence, D.P.4    Sosman, J.A.5    Infante, J.R.6
  • 15
    • 84882832283 scopus 로고    scopus 로고
    • Initial results from a phase I, open-label, dose escalation study of the oral BRAF inhibitor LGX818 in patients with BRAF V600 mutant advanced or metastatic melanoma [abstract]
    • Dummer R, Robert C, Nyakas M, McArthur GA, Kudchadkar RR, Gomez-Roca C, et al. Initial results from a phase I, open-label, dose escalation study of the oral BRAF inhibitor LGX818 in patients with BRAF V600 mutant advanced or metastatic melanoma [abstract]. J Clin Oncol 2013;31:9028.
    • (2013) J Clin Oncol , vol.31 , pp. 9028
    • Dummer, R.1    Robert, C.2    Nyakas, M.3    McArthur, G.A.4    Kudchadkar, R.R.5    Gomez-Roca, C.6
  • 16
    • 84882898838 scopus 로고    scopus 로고
    • Phase 1B study of vemurafenib in combination with the MEK inhibitor, GDC-0973, in patients (pts) with unresectable or metastatic BRAFV600 mutated melanoma (BRIM7)
    • Gonzalez R, Ribas A, Daud A, Pavlick A, Gajewski TF, Puzanov I, et al. Phase 1B study of vemurafenib in combination with the MEK inhibitor, GDC-0973, in patients (pts) with unresectable or metastatic BRAFV600 mutated melanoma (BRIM7). Ann Oncol 2012;23:ixe19 (abstract LBA28-PR).
    • (2012) Ann Oncol , vol.23 , pp. ixe19
    • Gonzalez, R.1    Ribas, A.2    Daud, A.3    Pavlick, A.4    Gajewski, T.F.5    Puzanov, I.6
  • 17
    • 84882829380 scopus 로고    scopus 로고
    • Preliminary results from a phase Ib/II, open-label, dose-escalation study of the oral BRAF inhibitor LGX818 in combination with the oral MEK1/2 inhibitor MEK162 in BRAF V600-dependent advanced solid tumors [abstract]
    • Kefford R, Miller WH, DS-W Tan, Sullivan RJ, Long G, Dienstmann R, et al. Preliminary results from a phase Ib/II, open-label, dose-escalation study of the oral BRAF inhibitor LGX818 in combination with the oral MEK1/2 inhibitor MEK162 in BRAF V600-dependent advanced solid tumors [abstract]. J Clin Oncol 2013;31:9029.
    • (2013) J Clin Oncol , vol.31 , pp. 9029
    • Kefford, R.1    Miller, W.H.2    Tan, D.S.-W.3    Sullivan, R.J.4    Long, G.5    Dienstmann, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.