The genomic diversity of prostate cancer: Our achilles heel explored

European Urology

Volumn 67, Issue 5, 2015, Pages 823-824

  Bryant, Richard J ^a   Verrill, Clare ^a   Hamdy, Freddie C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN; DNA;

CANCER PATIENT; CLINICAL DECISION MAKING; CLINICAL EVALUATION; EDITORIAL; EXOME; FOLLOW UP; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOMICS; GERMLINE MUTATION; GLEASON SCORE; HUMAN; INTRADUCTAL CARCINOMA; LASER MICRODISSECTION; LYMPH NODE METASTASIS; MOLECULAR DIAGNOSTICS; PHENOTYPE; PRIORITY JOURNAL; PROSTATE CANCER; SEMINAL VESICLE; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; TUMOR INVASION; BIOPSY; MALE; METABOLISM; NEOPLASM METASTASIS; PAGET NIPPLE DISEASE; PATHOLOGY; PROCEDURES; PROSTATE; PROSTATE TUMOR;

BIOPSY; CARCINOMA, DUCTAL; DNA; HUMANS; MALE; NEOPLASM METASTASIS; PROSTATE; PROSTATIC NEOPLASMS;

EID: 84926042646     PISSN: 03022838     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2014.11.026     Document Type: Editorial

References (11)

1. J. Lindberg, A. Kristiansen, P. Wiklund, H. Grönberg, and L. Egevad Tracking the origin of metastatic prostate cancer Eur Urol 67 2015 819 822
2. J. Lindberg, I.G. Mills, and D. Klevebring The mitochondrial and autosomal mutation landscapes of prostate cancer Eur Urol 63 2013 702 708
3. D. Trudel, M.R. Downes, J. Sykes, K.J. Kron, J. Trachtenberg, and T.H. van der Kwast Prognostic impact of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary cohort Eur J Cancer 50 2014 1610 1616
4. M.C. Haffner, T. Mosbruger, and D.M. Esopi Tracking the clonal origin of lethal prostate cancer J Clin Invest 123 2013 4918 4922
5. W. Liu, S. Laitinen, and S. Khan Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer Nat Med 15 2009 559 565
6. D. Brocks, Y. Assenov, S. Minner, et al ICGC Early Onset Prostate Cancer Project Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer Cell Rep 8 2014 798 806
7. Kweldam CF, Wildhagen MF, Steyerberg EW, Bangma CH, van der Kwast TH, van Leenders GJ. Cribriform growth is highly predictive for postoperative metastasis and disease-specific death in Gleason score 7 prostate cancer. Mod Pathol. In press. http://dx.doi.org/10.1038/modpathol.2014.116
8. R. Arora, M.O. Koch, J.N. Eble, T.M. Ulbright, L. Li, and L. Cheng Heterogeneity of Gleason grade in multifocal adenocarcinoma of the prostate Cancer 100 2004 2362 2366
9. N.L. Sharma, C.E. Massie, and A. Ramos-Montoya The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man Cancer Cell 23 2013 35 47
10. T.H. Van der Kwast, and M.J. Roobol Defining the threshold for significant versus insignificant prostate cancer Nat Rev Urol 10 2013 473 482
11. Klotz L, L. Zhang, A. Lam, R. Nam, A. Mamedov, and A. Loblaw Clinical results of long-term follow-up of a large, active surveillance cohort with localized prostate cancer J Clin Oncol 28 2010 126 131