Replicative study of GWAS TP63C/T, TERTC/T, and SLC14A1C/T with susceptibility to bladder cancer in North Indians1Equal contribution

Urologic Oncology: Seminars and Original Investigations

Volumn 32, Issue 8, 2014, Pages 1209-1214

  Singh, Vibha ^a   Jaiswal, Praveen Kumar ^a   Mittal, Rama Devi ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Bladder cancer; Genome wide association studies (GWAS); RFLP; Single nucleotide polymorphisms

Indexed keywords

CISPLATIN; GEMCITABINE; CARRIER PROTEIN; TELOMERASE; TERT PROTEIN, HUMAN; TP63 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; UREA TRANSPORTER;

ADULT; ARTICLE; BLADDER CANCER; CANCER RISK; CANCER SUSCEPTIBILITY; CASE CONTROL STUDY; CONTROLLED STUDY; CYSTECTOMY; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SLC14A1C T GENE; SMOKING; TERTC T GENE; TP63C T GENE; ASIAN CONTINENTAL ANCESTRY GROUP; BLADDER TUMOR; GENETIC PREDISPOSITION; GENETICS; INDIA; MIDDLE AGED; PATHOLOGY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TREATMENT OUTCOME;

ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INDIA; MALE; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; TELOMERASE; TRANSCRIPTION FACTORS; TREATMENT OUTCOME; TUMOR SUPPRESSOR PROTEINS; URINARY BLADDER NEOPLASMS;

EID: 84925945174     PISSN: 10781439     EISSN: 18732496     Source Type: Journal    
DOI: 10.1016/j.urolonc.2014.05.013     Document Type: Article

References (21)

1. Franekova M., Halasova E., Bukovska E., Luptak J., Dobrota D. Gene polymorphisms in bladder cancer. Urol Oncol 2008, 26:1-8.
2. Sinha R., Anderson D.E., McDonald S.S., Greenwald P. Cancer risk and diet in India. J Postgrad Med 2003, 49:222-228.
3. Kaufman D.S., Shipley W.U., Feldman A.S. Bladder cancer. Lancet 2009, 374:239-249.
4. Wu G.Y., Hasenberg T., Magdeburg R., Bonninghoff R., Sturm J.W., Keese M. Association between EGF, TGF-beta1, VEGF gene polymorphism and colorectal cancer. World J Surg 2009, 33:124-129.
5. Kiltie A.E. Common predisposition alleles for moderately common cancers bladder cancer. Curr Opin Genet Dev 2010, 20:218-224.
6. Lantuejoul S., Salon C., Soria J.C., Brambilla E. Telomerase expression in lung preneoplasia and neoplasia. Int J Cancer 2007, 120:1835-1841.
7. Comperat E., Bieche I., Dargere D., et al. p63 gene expression study and early bladder carcinogenesis. Urology 2007, 70:459-462.
8. Urist M.J., Di Como C.J., Lu M.L., et al. Loss of p63 expression is associated with tumor progression in bladder cancer. Am J Pathol 2002, 161:1199-1206.
9. Zigeuner R., Tsybrovskyy O., Ratschek M., Rehak P., Lipsky K., Langner C. Prognostic impact of p63 and p53 expression in upper urinary tract transitional cell carcinoma. Urology 2004, 63:1079-1083.
10. Kiemeney L.A., Thorlacius S., Sulem P., et al. Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat Genet 2008, 40:1307-1312.
11. Garcia-Closas M., Ye Y., Rothman N., et al. A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. Hum Mol Genet 2011, 20:4282-4289.
12. Colombel M., Soloway M., Akaza H., et al. Epidemiology, staging, grading, and risk stratification of bladder cancer. Eur Urol 2008, 7(Suppl):618-626.
13. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988, 16:1215.
14. Gago-Dominguez M., Jiang X., Conti D.V., et al. Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study. Carcinogenesis 2011, 32:197-202.
15. Jin E.C., Kang H.G., Jin S.J., et al. Polymorphisms in telomere maintenance genes and risk of lung cancer. Cancer Epidemiol Biomarker Prev 2009, 18:2773-2781.
16. Chen H., Chen Y., Zhao Y., et al. Association of sequence variants on chromosomes 20, 11, and 5 (20q13.33, 11q23.3, and 5p15.33) with glioma susceptibility in a Chinese population. Am J Epidemiol 2011, 173:915-922.
17. Savage S.A., Chanock S.J., Lissowska J., et al. Genetic variation in five genes important in telomere biology and risk for breast cancer. Br J Cancer 2007, 97:832-836.
18. Wang M., Wang M., Zhang W., et al. Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population. Carcinogenesis 2009, 6:991-996.
19. Stewart G. The emerging physiological roles of the SLC14A family of urea transporters. Br J Pharmacol 2011, 164:1780-1792.
20. Rafnar T., Vermeulen S.H., Sulem P., et al. European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene. Hum Mol Genet 2011, 20:4268-4281.
21. Koutros S., Baris D., Fischer A., et al. Differential urinary specific gravity as a molecular phenotype of the bladder cancer genetic association in the urea transporter gene, SLC14A1. Int J Cancer 2013, 133:3008-3013.