Effects of sugar-free chewing gum sweetened with xylitol or maltitol on the development of gingivitis and plaque: A randomized clinical trial

International Journal of Dental Hygiene

Volumn 12, Issue 4, 2014, Pages 238-244

  Keukenmeester, R S ^a   Slot, D E ^a   Rosema, N A M ^a   Van Loveren, C ^a   Van der Weijden, G A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Chewing gum; Gingivitis; Maltitol; Plaque; Randomized clinical trial; Xylitol

Indexed keywords

CHEWING GUM; MALTITOL; MALTOSE; SUGAR ALCOHOL; SWEETENING AGENT; XYLITOL;

ADOLESCENT; ADULT; ANALOGS AND DERIVATIVES; CHEWING GUM; COMPARATIVE STUDY; CONTROLLED STUDY; DENTAL PLAQUE; DOUBLE BLIND PROCEDURE; FEMALE; GINGIVITIS; HUMAN; MALE; MOUTH HYGIENE; PERIODONTICS; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; TOOTH BRUSHING; TOOTH PLAQUE; YOUNG ADULT;

ADOLESCENT; ADULT; CHEWING GUM; DENTAL PLAQUE; DENTAL PLAQUE INDEX; DOUBLE-BLIND METHOD; FEMALE; GINGIVITIS; HUMANS; MALE; MALTOSE; ORAL HYGIENE; PERIODONTAL INDEX; SUGAR ALCOHOLS; SWEETENING AGENTS; TOOTHBRUSHING; XYLITOL; YOUNG ADULT;

EID: 84925944537     PISSN: 16015029     EISSN: 16015037     Source Type: Journal    
DOI: 10.1111/idh.12071     Document Type: Article

References (23)

1. International Chewing Gum Association. Available at: http://www.gumassociation.org (accessed 22 December 2013).
2. Ly KA, Milgrom P, Rothen M. The potential of dental-protective chewing gum in oral health interventions. J Am Dent Assoc 2008; 139: 553-563.
3. Burt BA. The use of sorbitol- and xylitol-sweetened chewing gum in caries control. J Am Dent Assoc 2006; 137: 190-196.
4. Mickenautsch S, Leal SC, Yengopal V, Bezerra AC, Cruvinel V. Sugar-free chewing gum and dental caries: a systematic review. J Appl Oral Sci 2007; 15: 83-88.
5. Deshpande A, Jadad AR. The impact of polyol-containing chewing gums on dental caries: a systematic review of original randomized controlled trials and observational studies. J Am Dent Assoc 2008; 139: 1602-1614.
6. Keukenmeester RS, Slot DE, Putt MS, Van der Weijden GA. The effect of sugar-free chewing gum on plaque and clinical parameters of gingival inflammation: a systematic review. Int J Dent Hyg 2013; 11: 2-14.
7. Löe H, Theilade E, Jensen SB. Experimental gingivitis in man. J Periodontol 1965; 36: 177-187.
8. Wennström JL. Mouthrinses in "experimental gingivitis" studies. J Clin Periodontol 1988; 15: 511-516.
9. Van der Weijden GA, Timmerman MF, Reijerse E, Nijboer A, Van der Velden U. Comparison of different approaches to assess bleeding on probing as indicators of gingivitis. J Clin Periodontol 1994; 21: 589-594.
10. Van der Weijden GA, Timmerman MF, Saxton CA, Russell JI, Huntington E, Van der Velden U. Intra-/ Inter-examiner reproducibility study of gingival bleeding. J Periodontal Res 1994; 29: 236-241.
11. Lie MA, Timmerman MF, Van der Velden U, Van der Weijden GA. Evaluation of two methods to assess gingival bleeding in smokers and non-smokers in natural and experimental gingivitis. J Clin Periodontol 1998; 25: 695-700.
12. Dupont WD, Plummer WD. PS power and sample size program available for free on the internet. Control Clin Trials 1997; 18: 274.
13. Rosema NA, Timmerman MF, Piscaer M et al. An oscillating/pulsating electric toothbrush versus a high-frequency electric toothbrush in the treatment of gingivitis. J Dent 2005; 33: 29-36.
14. Versteeg PA, Timmerman MF, Rosema NA, Warren PR, Van der Velden U, Van der Weijden GA. Sonic-powered toothbrushes and reversal of experimental gingivitis. J Clin Periodontol 2005; 32: 1236-1241.
15. Turesky S, Gilmore ND, Glickman L. Reduced formation by chloromethyl analogue of victamine C. J Periodontol 1970; 41: 41-43.
16. Quigley GA, Hein JW. Comparative cleansing efficiency of manual and power brushing. J Am Dent Assoc 1962; 65: 26-29.
17. Paraskevas S, Rosema NA, Versteeg P, Timmerman MF, Van der Velden U, Van der Weijden GA. The additional effect of a dentifrice on the instant efficacy of tooth brushing: a crossover study. J Periodontol 2007; 78: 1011-1016.
18. Slot DE, Rosema NA, Hennequin-Hoenderdos NL, Versteeg PA, Van der Velden U, Van der Weijden GA. The effect of 1% chlorhexidine gel and 0.12% dentifrice gel on plaque accumulation: a 3-day non-brushing model. Int J Dent Hyg 2010; 8: 294-300.
19. Lesaffre E, Feine J, Leroux B, Declerck D. Statistical and methodological aspects of oral health research. Chichester (UK): John Wiley & Sons; 2009. 83.
20. American Dental Association: Guideline for Product Acceptance, July 2011. Available at: http://www.ada.org/sections/scienceAndResearch/pdfs/guide_adjunctive.pdf (accessed 22 December 2013).
21. Altman DG. Statistics and ethics in medical research, III: how large a sample? BMJ 1980; 281: 1336-1338.
22. Dupont WD, Plummer WD. Power and sample size calculations: a review and computer program. Control Clin Trials 1990; 11: 116-128.
23. Rosenhek M, Macpherson LM, Dawes C. The effects of chewing-gum stick size and duration of chewing on salivary flow rate and sucrose and bicarbonate concentrations. Arch Oral Biol 1993; 38: 885-891.