Effects of pancreas transplantation on the prevention and reversal of diabetic nephropathy

Contributions to Nephrology

Volumn 170, Issue , 2011, Pages 237-246

  Fioretto, Paola ^a   Mauer, Michael ^b  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; DIABETIC NEPHROPATHY; GLOMERULUS; HUMAN; KIDNEY TRANSPLANTATION; PANCREAS TRANSPLANTATION; PATHOLOGY;

ANIMALS; DIABETIC NEPHROPATHIES; HUMANS; KIDNEY GLOMERULUS; KIDNEY TRANSPLANTATION; PANCREAS TRANSPLANTATION;

EID: 84925937209     PISSN: 03025144     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000325747     Document Type: Article

References (42)

1. US Renal Data System: US Renal Data System Annual Report. Bethesda, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2006.
2. Mauer M, Fioretto P, Woredekal Y, et al: Diabetic nephropathy; in Schrier RW (ed): Disease of the Kidney and Urinary Tract. Philadelphia, Lippincott Williams & Wilkins, 2001, pp 2083-2127.
3. Mauer SM, Steffes MW, Ellis EN, et al: Structural-functional relationships in diabetic nephropathy. J Clin Invest 1984;74:1143-1155. (Pubitemid 15210185)
4. Lewis EJ, Hunsicker LG, Bain RP, et al: The effect of angiotensin-converting enzyme inhibition on diabetic nephropathy. N Engl J Med 1993;329:1456-1462. (Pubitemid 23335891)
5. Lewis EJ, Hunsicker LG, Clarke WR, et al, for the Collaborative Study Group: Renoprotective effect of the angiotensinreceptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001;345:851-860.
6. Brenner BM, Cooper ME, De Zeeuw D, et al, for the Renal Study Investigators: Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001;345: 861-869.
7. Mauer M, Zinman B, Gardiner R, Suissa S, Sinaiko A, Strand T, Drummond K, Donnelly S, Goodyer P, Gubler MC, Klein R: Renal and retinal effects of Enalapril and Losartan in type 1 diabetes. N Engl J Med 2009;361: 40-51.
8. Østerby R: Early phases in the development of diabetic glomerulopathy. Acta Med Scand 1975;475:1-84.
9. Pirart J: Diabetes mellitus and its degenerative complications: A prospective study of 4,400 patients observed between 1947 and 1973. Diabetes Metab 1977;3:173-182. (Pubitemid 8190305)
10. Diabetes Complications and Control Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications of insulin dependent diabetes mellitus. N Engl J Med 1993;329:977-986.
11. Parving H-H, Rossing P, Hommel E, et al: Angiotensin-converting enzyme inhibition in diabetic nephropathy: Ten years' experience. Am J Kidney Dis 1995;26:99-107.
12. Steffes MW, Sutherland DER, Goetz FC, et al: Studies of kidney and muscle biopsy specimens from identical twins discordant for type I diabetes mellitus. N Engl J Med 1985; 312:1282-1287. (Pubitemid 15033061)
13. Mauer SM, Goetz FC, McHugh LE, et al: Long-term study of normal kidneys transplanted into patients with type I diabetes. Diabetes 1989;38:516-523. (Pubitemid 19105413)
14. Mauer SM, Steffes MW, Connett J, et al: The development of lesions in the glomerular basement membrane and mesangium after transplantation of normal kidneys into diabetic patients. Diabetes 1983;32:948-952. (Pubitemid 13000659)
15. Barbosa J, Steffes MW, Sutherland DER, et al: The effect of glycemic control on early diabetic renal lesions. A 5-year randomized controlled clinical trial of insulin-dependent diabetic kidney transplant recipients. JAMA 1994;272:600-606. (Pubitemid 24255218)
16. UKPDS Group: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. Lancet 1998;352:837-853.
17. Fioretto P, Steffes MW, Sutherland DER, et al: Reversal of lesions of diabetic nephropathy after pancreas transplantation. N Engl J Med 1998;339:69-75. (Pubitemid 28304880)
18. Fioretto P, Steffes MW, Mauer SM: Glomerular structure in non-proteinuric insulin-dependent diabetic patients with various levels of albuminuria. Diabetes 1994;43: 1358-1364.
19. Brito PL, Fioretto P, Drummond K, et al: Proximal tubular basement membrane width in insulin-dependent diabetes mellitus. Kidney Int 1998;53:754-761. (Pubitemid 28124292)
20. Steffes MW, Bilous RW, Sutherland DER, et al: Cell and matrix components of the glomerular mesangium in type I diabetes. Diabetes 1992;41:679-684.
21. Falk RJ, Scheinman JI, Mauer SM, et al: Polyantigenic expansion of basement membrane constituents in diabetic nephropathy. Diabetes 1983;32:34-39. (Pubitemid 13099680)
22. Zhu D, Kim Y, Steffes MW, et al: Glomerular distribution of type IV collagen in diabetes by high resolution quantitative immunochemistry. Kidney Int 1994;45:425-433. (Pubitemid 24065076)
23. Moriya T, Groppoli TJ, Kim Y, et al: Quantitative immunoelectron microscopy of type VI collagen in glomeruli in type I diabetic patients. Kidney Int 2001;59:317-323. (Pubitemid 32055239)
24. Steffes MW, Barbosa J, Basgen JM, Sutherland DER, Najarian JS, Mauer SM: Quantitative glomerular morphology of the normal human kidney. Lab Invest 1983;49: 82-86. (Pubitemid 13078971)
25. Bohman S-O, Tyden G, Wilczek H, Lundgren G, Jaremko G, Gunnarsson R, Ostman J, Groth G: Prevention of kidney graft diabetic nephropathy by pancreas transplantation in man. Diabetes 1985;34:306-308. (Pubitemid 15134793)
26. Bohman S-O, Wilczek H, Tyden G, Jaremko G, Lundgren G, Groth G: Recurrent diabetic nephropathy in renal allografts placed in diabetic patients and protective effect of simultaneous pancreas transplantation. Transplant Proc 1987;1:2290-2293.
27. Wilczek HE, Jaremko G, Tyden G, Groth CG: Pancreatic graft protects a simultaneously transplanted kidney from developing diabetic nephropathy: A 1 to 6 year follow-up study. Transplant Proc 1993;1:1314-1315. (Pubitemid 23079000)
28. Nyberg G, Holdaas H, Brekke IB, et al: Glomerular ultrastructure in kidneys transplanted simultaneously with a segmental pancreas to patients with type 1 diabetes. Nephrol Dial Transplant 1996;11:1029-1033. (Pubitemid 26182494)
29. Bilous RW, Mauer SM, Sutherland DER, et al: The effects of pancreas transplantation on the glomerular structure of renal allografts in patients with insulin-dependent diabetes. N Engl J Med 1989;32:80-85. (Pubitemid 19170396)
30. Mauer SM, Sutherland DER, Steffes MW, et al: Pancreatic islet transplantation. Effects on the glomerular lesions of experimental diabetes in the rat. Diabetes 1974;23:748-753.
31. Pugliese G, Pricci F, Pesce C, et al: Early, but not advanced, glomerulopathy is reversed by pancreatic islet transplants in experimental diabetic rats: Correlation with glomerular extracellular matrix mRNA levels. Diabetes 1997;46:1198-2006.
32. Mauer SM, Steffes MW, Sutherland DER, et al: Studies of the rate of regression of the glomerular lesions in diabetic rats treated with pancreatic islet transplantation. Diabetes 1975;24:280-285.
33. Steffes MW, Brown DM, Basgen JM, et al: Amelioration of mesangial volume and surface alterations following islet transplantation in diabetic rats. Diabetes 1980;29: 509-515. (Pubitemid 12180507)
34. Steffes MW, Brown DM, Basgen JM, et al: Glomerular basement membrane thickness following islet transplantation in the diabetic rat. Lab Invest 1979;41:116-118. (Pubitemid 9244545)
35. Fioretto P, Mauer SM, Bilous RW, et al: Effects of pancreas transplantation on glomerular structure in insulin-dependent diabetic patients with their own kidneys. Lancet 1993;342:1193-1196. (Pubitemid 23331708)
36. Fioretto P, Steffes MW, Mihach MJ, et al: Cyclosporine associated lesions in native kidneys of diabetic pancreas transplant recipients. Kidney Int 1995;48:489-495.
37. Roys S, Sala R, Cagliero E, et al: Overexpression of fibronectin induced by diabetes or high glucose: Phenomenon with a memory. Proc Nat Acad Sci USA 1990;87: 404-408.
38. Brownlee M, Cerami A, Vlassara H: Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N Engl J Med 1988;318: 1315-1322.
39. Krolewski AS, Warram JH, Christleb AR, et al: The changing natural history of nephropathy in type I diabetes. Am J Med 1985;78: 785-794. (Pubitemid 15008233)
40. Myers BD, Sibley R, Newton L, et al: The long-term course of cyclosporineassociated chronic nephropathy. Kidney Int 1988;33:590-600. (Pubitemid 18073785)
41. Feutren G, Mihatsch MJ: Risk factors for cyclosporine induced nephropathy in patients with autoimmune diseases. N Engl J Med 1992;326:1654-1660.
42. Fioretto P, Sutherland DER, Najafian B, Mauer M: Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients. Kidney Int 2006;69:907-912.