Leukoencephalopathy: Before concluding treatment efficacy

Neurology

Volumn 84, Issue 3, 2015, Pages 218-219

  Gilden, Don ^a   Schiffmann, Raphael ^b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID TRANSFER RNA; IBUPROFEN; METHYLPREDNISOLONE; ASPARTATE TRANSFER RNA LIGASE; STEROID;

ADOLESCENT; BRAIN STEM; CEREBROSPINAL FLUID; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; EDITORIAL; EVOKED SOMATOSENSORY RESPONSE; HUMAN; HUMAN TISSUE; LEARNING DISORDER; LEG; LEUKOENCEPHALOPATHY; MUSCLE STRENGTH; MUSCLE TONE; NERVE BIOPSY; NERVE CONDUCTION; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOGENESIS; PRIORITY JOURNAL; PYRAMIDAL TRACT; SPASTIC PARAPLEGIA; SPASTICITY; SPINAL CORD; SPINE; SURAL NERVE; TENDON REFLEX; VIBRATION SENSE; ENCEPHALITIS; FEMALE; GENETICS; LEUKOENCEPHALOPATHIES; MALE; MUTATION; PATHOPHYSIOLOGY;

ASPARTATE-TRNA LIGASE; ENCEPHALITIS; FEMALE; HUMANS; LEUKOENCEPHALOPATHIES; MALE; MUTATION; STEROIDS;

EID: 84925936394     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000001165     Document Type: Editorial

References (4)

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2. Scheper GC, van der Klok T, van Andel RJ, et al. Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation. Nat Genet 2007;39:534-539.
3. Taft RJ, Vanderver A, Leventer RJ, et al. Mutations in DARS cause hypomyelination and brain stem and spinal cord involvement and leg spasticity. Am J Hum Genet 2013;92:774-780.
4. Wolf NI, Toro C, Kister I, et al. DARS-associated leukoencephalopathy can mimic a steroid-responsive neuroinflammatory disorder. Neurology 2015;84:226-230.