Dihydroartemisinin inhibits glucose uptake and cooperates with glycolysis inhibitor to induce apoptosis in non-small cell lung carcinoma cells

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Mi, Yan Jun ^a,b   Geng, Guo Jun ^a   Zou, Zheng Zhi ^c   Gao, Jing ^a   Luo, Xian Yang ^a   Liu, Yu ^a   Li, Ning ^a   Li, Chun Lei ^a   Chen, Yu Qiang ^b   Yu, Xiu Yi ^a   Jiang, Jie ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

^b The Affiliated Chenggong Hospital of Xiamen University   (China)

^c Institute of Laser Life Science   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEOXYGLUCOSE; DIHYDROARTEMISININ; GLUCOSE; GLUCOSE TRANSPORTER 1; LACTIC ACID; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN S6; REACTIVE OXYGEN METABOLITE; ARTEMISININ DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL DESTRUCTION; CARCINOMA CELL LINE; CELL PROLIFERATION; CELL VIABILITY; COLONY FORMATION; CONTROLLED STUDY; CYTOPLASM; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENTIATION; GLUCOSE TRANSPORT; GLYCOLYSIS; LUNG FIBROBLAST; NON SMALL CELL LUNG CANCER; PROTEIN EXPRESSION; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BIOSYNTHESIS; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; HUMAN; LUNG TUMOR; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; ARTEMISININS; BIOLOGICAL TRANSPORT; CARCINOMA, NON-SMALL-CELL LUNG; CASPASE 8; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DEOXYGLUCOSE; DRUG SYNERGISM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLYCOLYSIS; HUMANS; LUNG NEOPLASMS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84925881056     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120426     Document Type: Article

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