Oral antioxidants supplementation for women with unexplained infertility undergoing ICSI/IVF: Randomized controlled trial

Human Fertility

Volumn 18, Issue 1, 2015, Pages 38-42

  Youssef, Mohamed A F M ^a,b,c   Abdelmoty, Hatem I ^a   Elashmwi, Hazem A ^a,b   Abduljawad, Esaad M ^b   Elghamary, Nevin ^a   Magdy, Ahmed ^a   Mohesen, Mohamed N ^d   Abdella, Rana M A ^a   Bar, Mostafa Abdel ^a   Gouda, Hisham M ^a   Ali, Ahmed Mahmoud Sayed ^a   Raslan, Ayman N ^a   Youssef, Dalia ^a   Sherif, Nadin A ^a   Ismail, Aboulfoutouh I ^a,b  

^a CAIRO UNIVERSITY   (Egypt)

^b Egyptian International Fertility IVF Center (EIFC IVF)   (Egypt)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d BENI SUEF UNIVERSITY   (Egypt)

Author keywords

Antioxidants; IVF ICSI; Ovarian stimulation

Indexed keywords

AMINO ACID; ANTIOXIDANT; FOLLITROPIN; MINERAL; MULTIVITAMIN; REACTIVE OXYGEN METABOLITE; CHELATING AGENT; FERTILITY PROMOTING AGENT; TRACE ELEMENT; VITAMIN;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; FEMALE; FEMALE SUBFERTILITY; FERTILIZATION IN VITRO; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; METAPHASE; OOCYTE; OOCYTE MATURATION; OVARY FOLLICLE; PREGNANCY RATE; RANDOMIZED CONTROLLED TRIAL; ADVERSE EFFECTS; DIET SUPPLEMENTATION; DIET THERAPY; DRUG EFFECTS; EGYPT; EPIDEMIOLOGY; FOLLOW UP; INFERTILITY, FEMALE; MULTIMODALITY CANCER THERAPY; OOCYTE DEVELOPMENT; OOCYTE RETRIEVAL; OVULATION INDUCTION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PREGNANCY;

ADULT; ANTIOXIDANTS; CHELATING AGENTS; COMBINED MODALITY THERAPY; DIETARY SUPPLEMENTS; EGYPT; FEMALE; FERTILITY AGENTS, FEMALE; FERTILIZATION IN VITRO; FOLLOW-UP STUDIES; HUMANS; INFERTILITY, FEMALE; LOST TO FOLLOW-UP; OOCYTE RETRIEVAL; OOGENESIS; OVULATION INDUCTION; OXIDATIVE STRESS; PREGNANCY; PREGNANCY RATE; SPERM INJECTIONS, INTRACYTOPLASMIC; TRACE ELEMENTS; VITAMINS;

EID: 84925880539     PISSN: 14647273     EISSN: 17428149     Source Type: Journal    
DOI: 10.3109/14647273.2014.927595     Document Type: Article

References (23)

1. Agarwal, A., Makker, K., & Sharma, R.(2008).Clinical relevance of oxidative stress in male factor infertility: an update.American Journal of Reproductive Immunology, 59, 2-11
2. Agarwal, A.& Sekhon, L.H.(2010).The role of antioxidant therapy in the treatment of male infertility.Human Fertility, 13, 217-225
3. Beckman, K.B.& Ames, B.N.(1998).The free radical theory of aging matures.Physiological Reviews, 78, 547-581
4. Chung, C.C., Fleming, R., Jamieson, M.E., Yates, R.W., & Coutts, J.R.(1995).Randomized comparison of ovulation induction with and without intrauterine insemination in the treatment of unexplained infertility.Human Reproduction, 10, 3139-3141
5. de Lamirande, E., Leclerc, P., & Gagnon, C.(1997).Capacitation as a regulatory event that primes spermatozoa for the acrosome reaction and fertilization.Molecular Human Reproduction, 3, 175-194
6. Desai, N.R., Mahfouz, R., Sharma, R., Gupta, S., & Agarwal, A.(2010).Reactive oxygen species levels are independent of sperm concentration, motility, and abstinence in a normal, healthy, proven fertile man: a longitudinal study.Fertility & Steril ity 94, 1541-1543
7. du Plessis, S.S., Makker, K., Desai, N.R., & Agarwal, A.(2008).Impact of oxidative stress on IVF.Expert Review of Obstetrics and Gynecology, 3, 539-554
8. Expert Group on Commissioning NHS Infertility Provision, Depart-ment of Health.(2009).Regulated Fertility Services: A Commissioning Aid - https://www.dh.gov.uk/publications.[Accessed: June 2013
9. Gué rin, P., El Mouatassim, S., & Mé né zo, Y.(2001).Oxidative stress and protection against reactive oxygen species in the preimplantation embryo and its surroundings.Human Reproduction Update, 7, 175-189
10. Isaksson, R.& Tiitinen, A.(1997).Superovulation combined with insemination or timed intercourse in the treatment of couples with unexplained infertility and minimal or mild endometriosis.Acta Obstetrica et Gynecologica Scandinavica, 76, 550-554
11. Jana, S.K., Narendra, B.K., Chattopadhyay, R., Chakravarty, B., & Chaudhury, K.(2010).Upper control limit of reactive oxygen species in follicular fl uid beyond which viable embryo formation is not favorable.Reproductive Toxicology, 29, 447-451
12. Martí n-Romero, F.J., Miguel-Lasobras, E.M., Domí nguez-Arroyo, J.A., González-Carrera, E., & Alvarez, I.S.(2008).Contribution of culture media to oxidative stress and its effect on human oocytes.Reproductive Biomedicine Online, 17, 652-661
13. Paszkowski, T., Traub, A.I., Robinson, S.Y., & McMaster, D.(1995).Selenium dependent glutathione peroxidase activity in human follicular fl uid.Clinica Chimica Acta, 236, 173-180
14. Sakkas, D., Urner, F., Bizzaro, D., Manicardi, G., Bianchi, P.G., Shoukir, Y., & Campana, A.(1998).Sperm nuclear DNA damage and altered chromatin structure: effect on fertilization and embryo development.Human Reproduction, 13, 11-19
15. Seino, T., Saito, H., Kaneko, T., Takahashi, T., Kawachiya, S., & Kurachi, H.(2002).Eight-hydroxy-2 -deoxyguanosine in granulosa cells is correlated with the quality of oocytes and embryos in an in vitro fertilization-embryo transfer program.Fertility & Sterility, 77, 1184-1190
16. Sikka, S.C.(1996).Oxidative stress and role of antioxidants in normal and abnormal sperm function.Frontiers in Bioscience, 1, e78-86
17. Sikka, S.C., Rajasekaran, M., & Hellstrom, W.J.(1995).Role of oxidative stress and antioxidants in male infertility.Journal of Andrology, 16, 464-468
18. Sugino, N., Takiguchi, S., Kashida, S., Karube, A., Nakamura, Y., & Kato, H.(2000).Superoxide dismutase expression in the human corpus luteum during the menstrual cycle and in early pregnancy.Molecular Human Reproduction, 6, 19-25
19. Suzuki, T., Sugino, N., Fukaya, T., Sugiyama, S., Uda, T., Takaya, R., et al.(1999).Superoxide dismutase in normal cycling human ovaries: immunohistochemical localization and characterization.Fertility & Steril ity, 72, 720-726
20. Takami, M., Preston, S.L., Toyloy, V.A, & Behrman, H.R.(1999).Antioxidants reversibly inhibit the spontaneous resumption of meiosis.American Journal of Physiology, 276, E684-688
21. Takenaka, M., Horiuchi, T., & Yanagimachi, R.(2007).Effects of light on development of mammalian zygotes.Proceedings of the National Academy of Sciences U S A, 104, 14289-14293
22. Tatemoto, H., Muto, N., Sunagawa, I., Shinjo, A., & Nakada, T.(2004).Protection of porcine oocytes against cell damage caused by oxidative stress during in vitro maturation: role of superoxide dismutase activity in porcine follicular fl uid.Biology of Reproduction, 71, 1150-1157
23. WHO.(2010).WHO Laboratory Manual for the Examination and Processing of Human Semen.5th edition.Geneva: World Health Organization, Department of Reproductive Health and Research 2010.[Accessed: June 2013