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Volumn 31, Issue 4, 2015, Pages 363-374

The shared neuroanatomy and neurobiology of comorbid chronic pain and PTSD: Therapeutic implications

Author keywords

Allopregnanolone; Chronic pain; Exercise; Neuropeptide Y; Posttraumatic stress disorder

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ALPHA 2 ADRENERGIC RECEPTOR; C REACTIVE PROTEIN; CANNABINOID 1 RECEPTOR; ELTANOLONE; GAMMA INTERFERON; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; MU OPIATE RECEPTOR; NEUROPEPTIDE Y; TUMOR NECROSIS FACTOR ALPHA;

EID: 84925876564     PISSN: 07498047     EISSN: 15365409     Source Type: Journal    
DOI: 10.1097/AJP.0000000000000115     Document Type: Review
Times cited : (85)

References (136)
  • 1
    • 0142151587 scopus 로고    scopus 로고
    • An examination of the relationship between chronic pain and post-traumatic stress disorder
    • Otis JD, Keane TM, Kerns RD. An examination of the relationship between chronic pain and post-traumatic stress disorder. J Rehabil Res Dev. 2003;40:397-405.
    • (2003) J Rehabil Res Dev , vol.40 , pp. 397-405
    • Otis, J.D.1    Keane, T.M.2    Kerns, R.D.3
  • 2
    • 0030750345 scopus 로고    scopus 로고
    • Chronic post-traumatic stress disorder and chronic pain in Vietnam combat veterans
    • Beckham JC, Crawford AL, Feldman ME, et al. Chronic post-traumatic stress disorder and chronic pain in Vietnam combat veterans. J Psychosom Res. 1997;43:379-389.
    • (1997) J Psychosom Res , vol.43 , pp. 379-389
    • Beckham, J.C.1    Crawford, A.L.2    Feldman, M.E.3
  • 3
    • 0036995241 scopus 로고    scopus 로고
    • PTSD and the experience of pain: Research and clinical implications of shared vulnerability and mutual maintenance models
    • Asmundson GJG, Coons MJ, Taylor S, et al. PTSD and the experience of pain: research and clinical implications of shared vulnerability and mutual maintenance models. Can J Psychiatry. 2002;47:930-937.
    • (2002) Can J Psychiatry , vol.47 , pp. 930-937
    • Asmundson, G.J.G.1    Coons, M.J.2    Taylor, S.3
  • 4
    • 0030220658 scopus 로고    scopus 로고
    • The relationship between symptoms of post-traumatic stress disorder and pain, affective disturbance and disability among patients with accident and non-accident related pain
    • Geisser ME, Roth RS, Bachman JE, et al. The relationship between symptoms of post-traumatic stress disorder and pain, affective disturbance and disability among patients with accident and non-accident related pain. Pain. 1996;66:207-214.
    • (1996) Pain , vol.66 , pp. 207-214
    • Geisser, M.E.1    Roth, R.S.2    Bachman, J.E.3
  • 5
    • 0029830264 scopus 로고    scopus 로고
    • Perception of traumatic onset, compensation status, and physical findings: Impact on pain severity, emotional distress, and disability in chronic pain patients
    • Turk DC, Okifuji A. Perception of traumatic onset, compensation status, and physical findings: impact on pain severity, emotional distress, and disability in chronic pain patients. J Behav Med. 1996;19:435-453.
    • (1996) J Behav Med , vol.19 , pp. 435-453
    • Turk, D.C.1    Okifuji, A.2
  • 6
    • 84990381073 scopus 로고    scopus 로고
    • Psychological problems associated with OEF/OIF deployment
    • Scioli ER, Otis JD, Keane TM. Psychological problems associated with OEF/OIF deployment. Am J Lifestyle Med. 2009;4:349-359.
    • (2009) Am J Lifestyle Med , vol.4 , pp. 349-359
    • Scioli, E.R.1    Otis, J.D.2    Keane, T.M.3
  • 7
    • 34250003163 scopus 로고    scopus 로고
    • Veterans seeking treatment for posttraumatic stress disorder: What about comorbid chronic pain?
    • Shipherd JC, Keyes M, Jovanovic T, et al. Veterans seeking treatment for posttraumatic stress disorder: what about comorbid chronic pain? J Rehabil Res Dev. 2007;44:153-166.
    • (2007) J Rehabil Res Dev , vol.44 , pp. 153-166
    • Shipherd, J.C.1    Keyes, M.2    Jovanovic, T.3
  • 8
    • 33750919074 scopus 로고    scopus 로고
    • The management of chronic pain in the primary care setting
    • James LC, Folen RA, eds. Washington, DC: American Psychological Association Press
    • Otis JD, Reid MC, Kerns RD. The management of chronic pain in the primary care setting. In: James LC, Folen RA, eds. Primary Care Clinical Health Psychology: A Model for the Next Frontier. Washington, DC: American Psychological Association Press; 2005:41-59.
    • (2005) Primary Care Clinical Health Psychology: A Model for the Next Frontier , pp. 41-59
    • Otis, J.D.1    Reid, M.C.2    Kerns, R.D.3
  • 10
  • 13
    • 0029999315 scopus 로고    scopus 로고
    • Role of the amygdala in the coordination of behavioral, neuroendocrine and prefrontal cortical monoamine responses to psychological stress in the rat
    • Goldstein LE, Rasmusson AM, Bunney BS, et al. Role of the amygdala in the coordination of behavioral, neuroendocrine and prefrontal cortical monoamine responses to psychological stress in the rat. J Neurosci. 1996;16:4787-4798.
    • (1996) J Neurosci , vol.16 , pp. 4787-4798
    • Goldstein, L.E.1    Rasmusson, A.M.2    Bunney, B.S.3
  • 14
    • 0025259299 scopus 로고
    • The spino(trigemino) pontoamygdaloid pathway: Electrophysiological evidence for an involvement in pain processes
    • Bernard JF, Besson JM. The spino(trigemino) pontoamygdaloid pathway: electrophysiological evidence for an involvement in pain processes. J Neurophysiol. 1990;63:473-490.
    • (1990) J Neurophysiol , vol.63 , pp. 473-490
    • Bernard, J.F.1    Besson, J.M.2
  • 15
    • 0043125664 scopus 로고    scopus 로고
    • Dendritic domains of nociceptive-responsive parabrachial neurons match terminal fields of lamina I neurons in the rat
    • Bourgeais L, Gauriau C, Monconduit L, et al. Dendritic domains of nociceptive-responsive parabrachial neurons match terminal fields of lamina I neurons in the rat. J Comp Neurol. 2003;464:238-256.
    • (2003) J Comp Neurol , vol.464 , pp. 238-256
    • Bourgeais, L.1    Gauriau, C.2    Monconduit, L.3
  • 16
    • 0035370306 scopus 로고    scopus 로고
    • Dopamine attenuates prefrontal cortical suppression of sensory inputs to the basolateral amygdala of rats
    • Rosenkranz JA, Grace AA. Dopamine attenuates prefrontal cortical suppression of sensory inputs to the basolateral amygdala of rats. J Neurosci. 2001;21:4090-4103.
    • (2001) J Neurosci , vol.21 , pp. 4090-4103
    • Rosenkranz, J.A.1    Grace, A.A.2
  • 17
    • 0026847155 scopus 로고
    • Brain mechanisms of emotion and emotional learning
    • LeDoux JE. Brain mechanisms of emotion and emotional learning. Curr Opin Neurobiol. 1992;2:191-197.
    • (1992) Curr Opin Neurobiol , vol.2 , pp. 191-197
    • LeDoux, J.E.1
  • 18
    • 33646114054 scopus 로고    scopus 로고
    • Opposing influence of basolateral amygdala and footshock stimulation on neurons of the central amygdala
    • Rosenkranz JA, Buffalari DM, Grace AA. Opposing influence of basolateral amygdala and footshock stimulation on neurons of the central amygdala. Biol Psychiatry. 2006;59:801-811.
    • (2006) Biol Psychiatry , vol.59 , pp. 801-811
    • Rosenkranz, J.A.1    Buffalari, D.M.2    Grace, A.A.3
  • 19
    • 84867247538 scopus 로고    scopus 로고
    • Central amygdala metabotropic glutamate receptor 5 in the modulation of visceral pain
    • Crock LW, Kolber BJ, Morgan CD, et al. Central amygdala metabotropic glutamate receptor 5 in the modulation of visceral pain. J Neurosci. 2012;32:14217-14226.
    • (2012) J Neurosci , vol.32 , pp. 14217-14226
    • Crock, L.W.1    Kolber, B.J.2    Morgan, C.D.3
  • 20
    • 11144298072 scopus 로고    scopus 로고
    • mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain
    • Han JS, Neugebauer V. mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain. Pain. 2005;113:211-222.
    • (2005) Pain , vol.113 , pp. 211-222
    • Han, J.S.1    Neugebauer, V.2
  • 21
    • 27944456383 scopus 로고    scopus 로고
    • Critical role of calcitonin gene-related peptide1 receptors in the amygdala in synaptic plasticity and pain behavior
    • Han JS, Li W, Neugebauer V. Critical role of calcitonin gene-related peptide1 receptors in the amygdala in synaptic plasticity and pain behavior. J Neurosci. 2005;25:10717-10728.
    • (2005) J Neurosci , vol.25 , pp. 10717-10728
    • Han, J.S.1    Li, W.2    Neugebauer, V.3
  • 22
    • 33847145480 scopus 로고    scopus 로고
    • Activation of the extracellular signal-regulated kinase in the amygdala modulates pain perception
    • Carrasquillo Y, Gereau RW IV. Activation of the extracellular signal-regulated kinase in the amygdala modulates pain perception. J Neurosci. 2007;27:1543-1551.
    • (2007) J Neurosci , vol.27 , pp. 1543-1551
    • Carrasquillo, Y.1    Gereau, R.W.2
  • 23
    • 0027222896 scopus 로고
    • Lesions of the amygdala block conditional hypoalgesia in the tail flick test
    • Helmstetter FD, Belgowan PS. Lesions of the amygdala block conditional hypoalgesia in the tail flick test. Brain Res. 1992;612:253-257.
    • (1992) Brain Res , vol.612 , pp. 253-257
    • Helmstetter, F.D.1    Belgowan, P.S.2
  • 24
    • 73949099064 scopus 로고    scopus 로고
    • The development of an integrated treatment for veterans with comorbid chronic pain and posttraumatic stress disorder
    • Otis JD, Keane TM, Kerns RD, et al. The development of an integrated treatment for veterans with comorbid chronic pain and posttraumatic stress disorder. Pain Med. 2009;10:1300-1311.
    • (2009) Pain Med , vol.10 , pp. 1300-1311
    • Otis, J.D.1    Keane, T.M.2    Kerns, R.D.3
  • 25
    • 84924405687 scopus 로고    scopus 로고
    • Integrating the neuroendocrinology, neurochemistry, and neuroimmunology of PTSD to date and the challenges ahead
    • Friedman M, Keane T, Resick P, eds. New York, NY: Guilford Publications Inc.
    • Rasmusson AM, Shalev A. Integrating the neuroendocrinology, neurochemistry, and neuroimmunology of PTSD to date and the challenges ahead. In: Friedman M, Keane T, Resick P, eds. Handbook of PTSD, Second Edition. New York, NY: Guilford Publications Inc.; 2014.
    • (2014) Handbook of PTSD, Second Edition
    • Rasmusson, A.M.1    Shalev, A.2
  • 27
    • 0028025568 scopus 로고
    • The pathophysiology of chronic pain - Increased sensitivity to low threshold A B-fibre inputs
    • Woolf CJ, Doubell TP. The pathophysiology of chronic pain - increased sensitivity to low threshold A B-fibre inputs. Curr Opin Neurobiol. 1994;4:525-534.
    • (1994) Curr Opin Neurobiol , vol.4 , pp. 525-534
    • Woolf, C.J.1    Doubell, T.P.2
  • 28
    • 0037061684 scopus 로고    scopus 로고
    • Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala
    • Tsvetkov E, Carlezon WA, Benes FM, et al. Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala. Neuron. 2002;34:289-300.
    • (2002) Neuron , vol.34 , pp. 289-300
    • Tsvetkov, E.1    Carlezon, W.A.2    Benes, F.M.3
  • 29
    • 33947330432 scopus 로고    scopus 로고
    • GABA-A receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: Possible insights into a non-serotonergic mechanism of action of SSRIs in mood and anxiety disorders
    • Matsumoto K, Puia G, Dong E, et al. GABA-A receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: possible insights into a non-serotonergic mechanism of action of SSRIs in mood and anxiety disorders. Stress. 2007;10:3-12.
    • (2007) Stress , vol.10 , pp. 3-12
    • Matsumoto, K.1    Puia, G.2    Dong, E.3
  • 30
    • 34547522672 scopus 로고    scopus 로고
    • The relationship of allopregnanolone immunoreactivity and HPA-axis measures to experimental pain sensitivity: Evidence for ethnic differences
    • Mechlin B, Morrow AL, Maixner W, et al. The relationship of allopregnanolone immunoreactivity and HPA-axis measures to experimental pain sensitivity: evidence for ethnic differences. Pain. 2007;131:142-152.
    • (2007) Pain , vol.131 , pp. 142-152
    • Mechlin, B.1    Morrow, A.L.2    Maixner, W.3
  • 31
    • 33748901641 scopus 로고    scopus 로고
    • Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder
    • Rasmusson AM, Pinna G, Paliwal P, et al. Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder. Biol Psychiatry. 2006;60:704-713.
    • (2006) Biol Psychiatry , vol.60 , pp. 704-713
    • Rasmusson, A.M.1    Pinna, G.2    Paliwal, P.3
  • 32
    • 0019475084 scopus 로고
    • Avian pancreatic polypeptide (APP) immunoreactive neurons in the spinal cord and spinal trigeminal nucleus
    • Hokfelt T, Lundberg JM, Jansco G, et al. Avian pancreatic polypeptide (APP) immunoreactive neurons in the spinal cord and spinal trigeminal nucleus. Peptides. 1981;2:81-87.
    • (1981) Peptides , vol.2 , pp. 81-87
    • Hokfelt, T.1    Lundberg, J.M.2    Jansco, G.3
  • 33
    • 0023684177 scopus 로고
    • Neuropeptide Y modulates neurotransmitter release and Ca2 + currents in rat sensory neurons
    • Walker MW, Ewald DA, Perney TM, et al. Neuropeptide Y modulates neurotransmitter release and Ca2 + currents in rat sensory neurons. J Neurosci. 1988;8:2438-2446.
    • (1988) J Neurosci , vol.8 , pp. 2438-2446
    • Walker, M.W.1    Ewald, D.A.2    Perney, T.M.3
  • 34
    • 0036220189 scopus 로고    scopus 로고
    • Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors
    • Taiwo OB, Taylor BK. Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors. Pain. 2002;96:353-363.
    • (2002) Pain , vol.96 , pp. 353-363
    • Taiwo, O.B.1    Taylor, B.K.2
  • 35
    • 27644527791 scopus 로고    scopus 로고
    • Involvement of neuropeptide Y and Y1 receptor in antinociception in the arcuate nucleus of hypothalamus, an immunohistochemical and pharmacological study in intact rats and rats with inflammation
    • Li J, Zhou X, Yu L. Involvement of neuropeptide Y and Y1 receptor in antinociception in the arcuate nucleus of hypothalamus, an immunohistochemical and pharmacological study in intact rats and rats with inflammation. Pain. 2005;118:232-242.
    • (2005) Pain , vol.118 , pp. 232-242
    • Li, J.1    Zhou, X.2    Yu, L.3
  • 36
    • 67651087154 scopus 로고    scopus 로고
    • Involvement of neuropeptie Y in the acute, chronic and withdrawal responses of morphine in nociception in neuropathic rats: Behavioral and neuroanatomical correlates
    • Upadhya MA, Dandekar MP, Kokare DM, et al. Involvement of neuropeptie Y in the acute, chronic and withdrawal responses of morphine in nociception in neuropathic rats: behavioral and neuroanatomical correlates. Neuropeptides. 2009;43:303-314.
    • (2009) Neuropeptides , vol.43 , pp. 303-314
    • Upadhya, M.A.1    Dandekar, M.P.2    Kokare, D.M.3
  • 37
    • 79955563200 scopus 로고    scopus 로고
    • Tonic inhibition of chronic pain by neuropeptide Y
    • Solway B, Bose SC, Corder G, et al. Tonic inhibition of chronic pain by neuropeptide Y. Proc Nat Acad Sci. 2011;108:7224-7229.
    • (2011) Proc Nat Acad Sci , vol.108 , pp. 7224-7229
    • Solway, B.1    Bose, S.C.2    Corder, G.3
  • 38
    • 84875988022 scopus 로고    scopus 로고
    • Opposing roles of corticotropin-releasing factor and neuropeptide Y within the dorsolateral bed nucleus of the stria terminalis in the negative affective component of pain in rats
    • Ide S, Hara T, Ohno A, et al. Opposing roles of corticotropin-releasing factor and neuropeptide Y within the dorsolateral bed nucleus of the stria terminalis in the negative affective component of pain in rats. J Neurosci. 2013;33:5881-5894.
    • (2013) J Neurosci , vol.33 , pp. 5881-5894
    • Ide, S.1    Hara, T.2    Ohno, A.3
  • 40
    • 77957843240 scopus 로고    scopus 로고
    • Adaptation to extreme stress: PTSD, NPY, and metabolic syndrome
    • Rasmusson AM, Schnurr P, Zukowska Z, et al. Adaptation to extreme stress: PTSD, NPY, and metabolic syndrome. Exp Biol Med. 2010;235:1150-1156.
    • (2010) Exp Biol Med , vol.235 , pp. 1150-1156
    • Rasmusson, A.M.1    Schnurr, P.2    Zukowska, Z.3
  • 41
    • 0027512327 scopus 로고
    • Neuropeptide Y-related peptides and their receptors - Are the receptors potential therapeutic drug targets?
    • Wahlestedt C, Reis DJ. Neuropeptide Y-related peptides and their receptors - are the receptors potential therapeutic drug targets? Ann Rev Pharmacol Toxicol. 1993;33:309-352.
    • (1993) Ann Rev Pharmacol Toxicol , vol.33 , pp. 309-352
    • Wahlestedt, C.1    Reis, D.J.2
  • 42
    • 0034014168 scopus 로고    scopus 로고
    • Plasma neuropeptide-Y concentrations in humans exposed to military survival training
    • Morgan CA III, Wang S, Southwick SM, et al. Plasma neuropeptide-Y concentrations in humans exposed to military survival training. Biol Psychiatry. 2000;47:902-909.
    • (2000) Biol Psychiatry , vol.47 , pp. 902-909
    • Morgan, C.A.1    Wang, S.2    Southwick, S.M.3
  • 43
    • 0037100255 scopus 로고    scopus 로고
    • Neuropeptide Y, cortisol, and subjective distress in humans exposed to acute stress: Replication and extension of previous report
    • Morgan CA III, Rasmusson AM, Wang S, et al. Neuropeptide Y, cortisol, and subjective distress in humans exposed to acute stress: replication and extension of previous report. Biol Psychiatry. 2002;52:136-142.
    • (2002) Biol Psychiatry , vol.52 , pp. 136-142
    • Morgan, C.A.1    Rasmusson, A.M.2    Wang, S.3
  • 44
    • 79953659017 scopus 로고    scopus 로고
    • Dissociation during intense military stress is related to subsequent somatic symptoms in women
    • Dimoulas E, Steffian G, Doran A, et al. Dissociation during intense military stress is related to subsequent somatic symptoms in women. Psychiatry. 2007;4:66-73.
    • (2007) Psychiatry , vol.4 , pp. 66-73
    • Dimoulas, E.1    Steffian, G.2    Doran, A.3
  • 45
    • 0343920026 scopus 로고    scopus 로고
    • Low baseline and yohimbine-stimulated plasma neuropeptide Y (NPY) levels in combat-related PTSD
    • Rasmusson AM, Hauger RL, Morgan CA III, et al. Low baseline and yohimbine-stimulated plasma neuropeptide Y (NPY) levels in combat-related PTSD. Biol Psychiatry. 2000; 47:526-539.
    • (2000) Biol Psychiatry , vol.47 , pp. 526-539
    • Rasmusson, A.M.1    Hauger, R.L.2    Morgan, C.A.3
  • 46
    • 69749125954 scopus 로고    scopus 로고
    • Sallee Low cerebrospinal fluid neuropeptide Y concentrations in post-traumatic stress disorder
    • Sah R, Ekhator NN, Strawn JR, et al. Sallee Low cerebrospinal fluid neuropeptide Y concentrations in post-traumatic stress disorder. Biol Psychiatry. 2009;66:705-707.
    • (2009) Biol Psychiatry , vol.66 , pp. 705-707
    • Sah, R.1    Ekhator, N.N.2    Strawn, J.R.3
  • 47
    • 33644817491 scopus 로고    scopus 로고
    • Plasma neuropeptide Y concentrations in combat exposed veterans: Relationship to trauma exposure, recovery from PTSD and coping
    • Yehuda R, Brand S, Yank RK. Plasma neuropeptide Y concentrations in combat exposed veterans: relationship to trauma exposure, recovery from PTSD and coping. Biol Psychiatry. 2005;59:660-663.
    • (2005) Biol Psychiatry , vol.59 , pp. 660-663
    • Yehuda, R.1    Brand, S.2    Yank, R.K.3
  • 48
    • 0026671993 scopus 로고
    • Central and peripheral effects of repeated stress and high NaCl diet on neuropeptide Y
    • Corder R, Castagne V, Rivet JM, et al. Central and peripheral effects of repeated stress and high NaCl diet on neuropeptide Y. Physiol Behav. 1992;52:205-210.
    • (1992) Physiol Behav , vol.52 , pp. 205-210
    • Corder, R.1    Castagne, V.2    Rivet, J.M.3
  • 49
    • 0242391909 scopus 로고    scopus 로고
    • Trauma exposure rather than posttraumatic stress disorder is associated with reduced baseline plasma neuropeptide-Y levels
    • Morgan CA III, Rasmusson AM, Winters B, et al. Trauma exposure rather than posttraumatic stress disorder is associated with reduced baseline plasma neuropeptide-Y levels. Biol Psychiatry. 2003;54:1087-1091.
    • (2003) Biol Psychiatry , vol.54 , pp. 1087-1091
    • Morgan, C.A.1    Rasmusson, A.M.2    Winters, B.3
  • 50
    • 0037502679 scopus 로고    scopus 로고
    • Plasma cortisol and neuropeptide Y in female victims of intimate partner violence
    • Seedat S, Stein MB, Kennedy CM, et al. Plasma cortisol and neuropeptide Y in female victims of intimate partner violence. Psychoneuroendocrinology. 2003;28:796-808.
    • (2003) Psychoneuroendocrinology , vol.28 , pp. 796-808
    • Seedat, S.1    Stein, M.B.2    Kennedy, C.M.3
  • 51
    • 0034093646 scopus 로고    scopus 로고
    • Hormone profiles in humans experiencing military survival training
    • Morgan CA III, Wang S, Mason J, et al. Hormone profiles in humans experiencing military survival training. Biol Psychiatry. 2000;47:891-901.
    • (2000) Biol Psychiatry , vol.47 , pp. 891-901
    • Morgan, C.A.1    Wang, S.2    Mason, J.3
  • 52
    • 79951476373 scopus 로고    scopus 로고
    • Emotion processing, major depression, and functional genetic variation of neuropeptide Y
    • Mickey BJ, Zhou Z, Heitzeg MM, et al. Emotion processing, major depression, and functional genetic variation of neuropeptide Y. Arch Gen Psychiatry. 2011;68:158-166.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 158-166
    • Mickey, B.J.1    Zhou, Z.2    Heitzeg, M.M.3
  • 53
    • 42549135962 scopus 로고    scopus 로고
    • Genetic variation in human NPY expression affects stress response and emotion
    • Zhou Z, Zhu G, Hariri AR, et al. Genetic variation in human NPY expression affects stress response and emotion. Nature. 2008;452:997-1001.
    • (2008) Nature , vol.452 , pp. 997-1001
    • Zhou, Z.1    Zhu, G.2    Hariri, A.R.3
  • 54
    • 0242552669 scopus 로고    scopus 로고
    • Neurosteroid modulation of GABAA receptors
    • Lambert JJ, Belelli D, Peden DR, et al. Neurosteroid modulation of GABAA receptors. Prog Neurobiol. 2003;71:67-80.
    • (2003) Prog Neurobiol , vol.71 , pp. 67-80
    • Lambert, J.J.1    Belelli, D.2    Peden, D.R.3
  • 55
    • 0037252696 scopus 로고    scopus 로고
    • On the putative physiological role of allopregnanolone on GABAA receptor function
    • Puia G, Mienville J-M, Matsumoto K, et al. On the putative physiological role of allopregnanolone on GABAA receptor function. Neuropharmacology. 2003;44:49-55.
    • (2003) Neuropharmacology , vol.44 , pp. 49-55
    • Puia, G.1    Mienville, J.-M.2    Matsumoto, K.3
  • 56
    • 53349127737 scopus 로고    scopus 로고
    • Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms
    • Charlet A, Lesbennes F, Darbon P, et al. Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms. Pain. 2008;139:603-609.
    • (2008) Pain , vol.139 , pp. 603-609
    • Charlet, A.1    Lesbennes, F.2    Darbon, P.3
  • 57
    • 0023182380 scopus 로고
    • Analgesic effects of the progesterone metabolite, 3 α-hydroxy-5 α-pregnan-20-one, and possible modes of action in mice
    • Kavaliers M, Wiebe JP. Analgesic effects of the progesterone metabolite, 3 α-hydroxy-5 α-pregnan-20-one, and possible modes of action in mice. Brain Res. 1987;415:393-398.
    • (1987) Brain Res , vol.415 , pp. 393-398
    • Kavaliers, M.1    Wiebe, J.P.2
  • 59
    • 1242328701 scopus 로고    scopus 로고
    • Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function
    • Cagetti E, Pinna G, Guidotti A, et al. Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function. Neuropharmacology. 2004;46:350-357.
    • (2004) Neuropharmacology , vol.46 , pp. 350-357
    • Cagetti, E.1    Pinna, G.2    Guidotti, A.3
  • 60
    • 0141957928 scopus 로고    scopus 로고
    • Gender differences in the regulation of 3-alpha-hydroxysteroid dehydrogenase in rat brain and sensitivity to neurosteroid-mediated stress protection
    • Mitev YA, Darwish M, Wolf SS, et al. Gender differences in the regulation of 3-alpha-hydroxysteroid dehydrogenase in rat brain and sensitivity to neurosteroid-mediated stress protection. Neuroscience. 2003;120:541-549.
    • (2003) Neuroscience , vol.120 , pp. 541-549
    • Mitev, Y.A.1    Darwish, M.2    Wolf, S.S.3
  • 61
    • 0031979258 scopus 로고    scopus 로고
    • Dexamethasone regulation of the Rat 3α-hydroxysteroid/dihydrodiol dehydrogenase gene
    • Hou Y-T, Lin H-K, Penning TM. Dexamethasone regulation of the Rat 3α-hydroxysteroid/dihydrodiol dehydrogenase gene. Mol Pharmacol. 1998;53:459-466.
    • (1998) Mol Pharmacol , vol.53 , pp. 459-466
    • Hou, Y.-T.1    Lin, H.-K.2    Penning, T.M.3
  • 62
    • 84875284885 scopus 로고    scopus 로고
    • Sex dependent influence of a functional polymorphism in steroid 5-alpha-reductase type 2 (SRD5A2) on post-traumatic stress symptoms
    • Gillespie CF, Almli LM, Smith AK, et al. Sex dependent influence of a functional polymorphism in steroid 5-alpha-reductase type 2 (SRD5A2) on post-traumatic stress symptoms. Am J Med Genet B Neuropsychiatr Genet. 2013;162B:283-292.
    • (2013) Am J Med Genet B Neuropsychiatr Genet , vol.162 B , pp. 283-292
    • Gillespie, C.F.1    Almli, L.M.2    Smith, A.K.3
  • 63
    • 81855161676 scopus 로고    scopus 로고
    • Molecular mechanisms of opioid receptor-dependent signaling and behavior
    • Al-Hasani R, Bruchas MR. Molecular mechanisms of opioid receptor-dependent signaling and behavior. Anesthesiology. 2011;115:1363-1381.
    • (2011) Anesthesiology , vol.115 , pp. 1363-1381
    • Al-Hasani, R.1    Bruchas, M.R.2
  • 64
    • 0346996861 scopus 로고    scopus 로고
    • Functional interactions between mu opioid and alpha 2A-adrenergic receptors
    • Jordan BA, Gomes I, Rios C, et al. Functional interactions between mu opioid and alpha 2A-adrenergic receptors. Mol Pharmacol. 2003;64:1317-1324.
    • (2003) Mol Pharmacol , vol.64 , pp. 1317-1324
    • Jordan, B.A.1    Gomes, I.2    Rios, C.3
  • 65
    • 0030611098 scopus 로고    scopus 로고
    • The alpha2 adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy
    • Stone L, MacMillan L, Kitto K, et al. The alpha2 adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy. J Neurosci. 1997;18:7157-7165.
    • (1997) J Neurosci , vol.18 , pp. 7157-7165
    • Stone, L.1    MacMillan, L.2    Kitto, K.3
  • 66
    • 0023449930 scopus 로고
    • Altered platelet alpha 2-adrenergic binding sites in posttraumatic stress disorder
    • Perry BD, Giller EL, Southwick SM. Altered platelet alpha 2-adrenergic binding sites in posttraumatic stress disorder. Am J Psychiatry. 1987;144:1511-1512.
    • (1987) Am J Psychiatry , vol.144 , pp. 1511-1512
    • Perry, B.D.1    Giller, E.L.2    Southwick, S.M.3
  • 67
    • 0033080761 scopus 로고    scopus 로고
    • Serotonergic and noradrenergic markers of post-traumatic stress disorder with and without major depression
    • Maes M, Lin AH, Verkerk R, et al. Serotonergic and noradrenergic markers of post-traumatic stress disorder with and without major depression. Neuropsychopharmacology. 1999;20:188-197.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 188-197
    • Maes, M.1    Lin, A.H.2    Verkerk, R.3
  • 68
    • 0028030717 scopus 로고
    • Effects of neuropeptide Y on the electrical properties of neurons
    • Colmers W, Bleakman D. Effects of neuropeptide Y on the electrical properties of neurons. Trends Neurosci. 1994;17:373-379.
    • (1994) Trends Neurosci , vol.17 , pp. 373-379
    • Colmers, W.1    Bleakman, D.2
  • 69
    • 0036682222 scopus 로고    scopus 로고
    • The endogenous cannabinoid system controls extinction of aversive memories
    • Marsicano G, Wotjak CT, Azad SC, et al. The endogenous cannabinoid system controls extinction of aversive memories. Nature. 2002;418:530-534.
    • (2002) Nature , vol.418 , pp. 530-534
    • Marsicano, G.1    Wotjak, C.T.2    Azad, S.C.3
  • 70
    • 13944267958 scopus 로고    scopus 로고
    • Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear
    • Chhatwal JP, Davis M, Maguschak KA, et al. Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear. Neuropsychopharmacology. 2005;30:516-524.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 516-524
    • Chhatwal, J.P.1    Davis, M.2    Maguschak, K.A.3
  • 71
    • 79952728977 scopus 로고    scopus 로고
    • Effect of 7,8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning
    • Andero R, Heldt SA, Ye K, et al. Effect of 7,8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning. Am J Psychiatry. 2013;168:163-172.
    • (2013) Am J Psychiatry , vol.168 , pp. 163-172
    • Andero, R.1    Heldt, S.A.2    Ye, K.3
  • 72
    • 84871281899 scopus 로고    scopus 로고
    • Serine 363 is required for nociceptin/orphanin FQ opioids receptor (NOPR) desensitization, internalization, and arrestin signaling
    • Zhang NR, Planer W, Siuda ER, et al. Serine 363 is required for nociceptin/orphanin FQ opioids receptor (NOPR) desensitization, internalization, and arrestin signaling. J Biol Chemistry. 2012;287:42019-42030.
    • (2012) J Biol Chemistry , vol.287 , pp. 42019-42030
    • Zhang, N.R.1    Planer, W.2    Siuda, E.R.3
  • 73
    • 84860540323 scopus 로고    scopus 로고
    • 2 +-stimulated adenylyl cyclases in bidirectional synaptic plasticity and brain function
    • 2 +-stimulated adenylyl cyclases in bidirectional synaptic plasticity and brain function. Rev Neurosci. 2012;23:67-78.
    • (2012) Rev Neurosci , vol.23 , pp. 67-78
    • Wang, H.1    Zhang, M.2
  • 74
    • 79957880321 scopus 로고    scopus 로고
    • Astrocytes support hippocampal-dependent memory and long-term potentiation via interleukin-1 signaling
    • Ben Menachem-Zidon O, Avital A, Ben-Menahem Y, et al. Astrocytes support hippocampal-dependent memory and long-term potentiation via interleukin-1 signaling. Brain Behav Immun. 2011;25:1008-1016.
    • (2011) Brain Behav Immun , vol.25 , pp. 1008-1016
    • Ben Menachem-Zidon, O.1    Avital, A.2    Ben-Menahem, Y.3
  • 75
    • 61849166110 scopus 로고    scopus 로고
    • Low cortisol, high DHEA, and high levels of stimulated TNF-α, and IL-6 in women with PTSD
    • Gill J, Vythilingam M, Page GG. Low cortisol, high DHEA, and high levels of stimulated TNF-α, and IL-6 in women with PTSD. JJ Trauma Stress. 2008;21:530-539.
    • (2008) JJ Trauma Stress , vol.21 , pp. 530-539
    • Gill, J.1    Vythilingam, M.2    Page, G.G.3
  • 77
    • 78349312880 scopus 로고    scopus 로고
    • Sustained elevation of serum interleukin-6 and relative insensitivity to hydrocortisone differentiates posttraumatic stress disorder with and without depression
    • Gill J, Luckenbaugh D, Charney D, et al. Sustained elevation of serum interleukin-6 and relative insensitivity to hydrocortisone differentiates posttraumatic stress disorder with and without depression. Biol Psychiatry. 2010;68:999-1006.
    • (2010) Biol Psychiatry , vol.68 , pp. 999-1006
    • Gill, J.1    Luckenbaugh, D.2    Charney, D.3
  • 78
    • 33748182420 scopus 로고    scopus 로고
    • Smoking as a complex but critical covariate in neurobiological studies of posttraumatic stress disorders: A review
    • Rasmusson AM, Picciotto MR, Krishnan-Sarin S. Smoking as a complex but critical covariate in neurobiological studies of posttraumatic stress disorders: a review. J Psychopharmacol. 2006;20:693-707.
    • (2006) J Psychopharmacol , vol.20 , pp. 693-707
    • Rasmusson, A.M.1    Picciotto, M.R.2    Krishnan-Sarin, S.3
  • 79
    • 27744584673 scopus 로고    scopus 로고
    • A twin registry study of the relationship between posttraumatic stress disorder and nicotine dependence in men
    • Koenen KC, Hitsman B, Lyons MJ, et al. A twin registry study of the relationship between posttraumatic stress disorder and nicotine dependence in men. Arch Gen Psychiatry. 2005;62:1258-1265.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1258-1265
    • Koenen, K.C.1    Hitsman, B.2    Lyons, M.J.3
  • 80
    • 82855161003 scopus 로고    scopus 로고
    • Pain, nicotine, and smoking: Research findings and mechanistic considerations
    • Zale EL, Meagher MM. Pain, nicotine, and smoking: research findings and mechanistic considerations. Psychol Bull. 2011;137:1065-1093.
    • (2011) Psychol Bull , vol.137 , pp. 1065-1093
    • Zale, E.L.1    Meagher, M.M.2
  • 81
    • 84857788632 scopus 로고    scopus 로고
    • Smoking cigarettes as a coping strategy for chronic pain is associated with greater pain intensity and poorer pain-related function
    • Patterson AL, Gritzner S, Resnick MP, et al. Smoking cigarettes as a coping strategy for chronic pain is associated with greater pain intensity and poorer pain-related function. J Pain. 2012;13:285-292.
    • (2012) J Pain , vol.13 , pp. 285-292
    • Patterson, A.L.1    Gritzner, S.2    Resnick, M.P.3
  • 82
    • 0034536613 scopus 로고    scopus 로고
    • Neuroendocrine and hormonal perturbations and relations to the serotonergic system in fibromyalgia patients
    • Neeck G. Neuroendocrine and hormonal perturbations and relations to the serotonergic system in fibromyalgia patients. Scand J Rheumatol. 2000;29:8-12.
    • (2000) Scand J Rheumatol , vol.29 , pp. 8-12
    • Neeck, G.1
  • 83
    • 0036672211 scopus 로고    scopus 로고
    • Prevalence of post-traumatic stress disorder in fibromyalgia patients: Overlapping syndromes or post-traumatic fibromyalgia syndrome?
    • Cohen H, Neumann L, Haiman Y, et al. Prevalence of post-traumatic stress disorder in fibromyalgia patients: overlapping syndromes or post-traumatic fibromyalgia syndrome? Semin Arthritis Rheum. 2002;32:38-50.
    • (2002) Semin Arthritis Rheum , vol.32 , pp. 38-50
    • Cohen, H.1    Neumann, L.2    Haiman, Y.3
  • 84
    • 32944462155 scopus 로고    scopus 로고
    • Childhood trauma and diurnal cortisol disruption in fibromyalgia syndrome
    • Weissbecker I, Floyd A, Dedert E, et al. Childhood trauma and diurnal cortisol disruption in fibromyalgia syndrome. Psychoneuroendocrinology. 2006;31:312-324.
    • (2006) Psychoneuroendocrinology , vol.31 , pp. 312-324
    • Weissbecker, I.1    Floyd, A.2    Dedert, E.3
  • 85
    • 0028917715 scopus 로고
    • Abuse-related posttraumatic stress disorder: Evidence for chronic neuroendocrine activation in women
    • Lemieux AM, Coe CL. Abuse-related posttraumatic stress disorder: evidence for chronic neuroendocrine activation in women. Psychosom Med. 1995;57:105-115.
    • (1995) Psychosom Med , vol.57 , pp. 105-115
    • Lemieux, A.M.1    Coe, C.L.2
  • 86
    • 0031866221 scopus 로고    scopus 로고
    • Abuse-related posttraumatic stress disorder and alterations of the hypothalamic-pituitary-adrenal axis in women with chronic pelvic pain
    • Heim C, Ehlert U, Hanker JP, et al. Abuse-related posttraumatic stress disorder and alterations of the hypothalamic-pituitary-adrenal axis in women with chronic pelvic pain. Psychosom Med. 1998;60:309-318.
    • (1998) Psychosom Med , vol.60 , pp. 309-318
    • Heim, C.1    Ehlert, U.2    Hanker, J.P.3
  • 87
    • 0035894627 scopus 로고    scopus 로고
    • Increased pituitary and adrenal reactivity in premenopausal women with posttraumatic stress disorder
    • Rasmusson AM, Lipschitz DS, Wang S, et al. Increased pituitary and adrenal reactivity in premenopausal women with posttraumatic stress disorder. Biol Psychiatry. 2001;50:965-977.
    • (2001) Biol Psychiatry , vol.50 , pp. 965-977
    • Rasmusson, A.M.1    Lipschitz, D.S.2    Wang, S.3
  • 88
    • 1842528209 scopus 로고    scopus 로고
    • Cortisol and catecholamines in posttraumatic stress disorder: An epidemiologic community study
    • Young EA, Breslau N. Cortisol and catecholamines in posttraumatic stress disorder: an epidemiologic community study. Arch Gen Psychiatry. 2004;61:394-401.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 394-401
    • Young, E.A.1    Breslau, N.2
  • 89
    • 84871717397 scopus 로고    scopus 로고
    • Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions
    • Klengel T, Mehta D, Anacker C, et al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci. 2013;16:33-41.
    • (2013) Nat Neurosci , vol.16 , pp. 33-41
    • Klengel, T.1    Mehta, D.2    Anacker, C.3
  • 90
    • 0031979258 scopus 로고    scopus 로고
    • Dexamethasone regulation of the rat 3α-hydroxysteroid/dihydrodiol dehydrogenase gene
    • Hou YT, Lin HK, Penning TM. Dexamethasone regulation of the rat 3α-hydroxysteroid/dihydrodiol dehydrogenase gene. Mol Pharmacol. 1998;53:459-466.
    • (1998) Mol Pharmacol , vol.53 , pp. 459-466
    • Hou, Y.T.1    Lin, H.K.2    Penning, T.M.3
  • 91
    • 34447116241 scopus 로고    scopus 로고
    • Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome
    • Kuo J, Kitlinska JB, Tilan JU, et al. Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome. Nat Med. 2007;13:803-811.
    • (2007) Nat Med , vol.13 , pp. 803-811
    • Kuo, J.1    Kitlinska, J.B.2    Tilan, J.U.3
  • 92
    • 0024790235 scopus 로고
    • Diurnal hormone variation in fibromyalgia syndrome: A comparison with rheumatoid arthritis
    • McCain GA, Tilbe KS. Diurnal hormone variation in fibromyalgia syndrome: a comparison with rheumatoid arthritis. J Rheumatol. 1989;19:154-157.
    • (1989) J Rheumatol , vol.19 , pp. 154-157
    • McCain, G.A.1    Tilbe, K.S.2
  • 93
    • 0028099256 scopus 로고
    • Hypothalamic-pituitary-adrenal axis perturbations in patients with fibromyalgia
    • Crofford LJ, Pillemer SR, Kalogeras KT, et al. Hypothalamic-pituitary-adrenal axis perturbations in patients with fibromyalgia. Arthritis Rheum. 1994;37:1583-1592.
    • (1994) Arthritis Rheum , vol.37 , pp. 1583-1592
    • Crofford, L.J.1    Pillemer, S.R.2    Kalogeras, K.T.3
  • 95
    • 0031835646 scopus 로고    scopus 로고
    • Function of the hypothalamic-pituitary-adrenal axis in patients with fibromyalgia and low back pain
    • Griep EN, Boersma JW, Lentjes EG, et al. Function of the hypothalamic-pituitary-adrenal axis in patients with fibromyalgia and low back pain. J Rheumatol. 1998;25:1374-1381.
    • (1998) J Rheumatol , vol.25 , pp. 1374-1381
    • Griep, E.N.1    Boersma, J.W.2    Lentjes, E.G.3
  • 96
    • 69849109461 scopus 로고    scopus 로고
    • Cortisol metabolic predictors of response to psychotherapy for symptoms of PTSD in survivors of the World Trade Center attacks on September 11, 2001
    • Yehuda R, Bierer LM, Sarapas C, et al. Cortisol metabolic predictors of response to psychotherapy for symptoms of PTSD in survivors of the World Trade Center attacks on September 11, 2001. Psychoneuroendocrinology. 2009;34:1304-1313.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 1304-1313
    • Yehuda, R.1    Bierer, L.M.2    Sarapas, C.3
  • 97
    • 16544385385 scopus 로고    scopus 로고
    • Gender differences in chronic pain - Findings from a population-based study of Norwegian adults
    • Rustoen T, Wahl AK, Hanestad BR, et al. Gender differences in chronic pain - findings from a population-based study of Norwegian adults. Pain Manag Nurs. 2004;5:105-117.
    • (2004) Pain Manag Nurs , vol.5 , pp. 105-117
    • Rustoen, T.1    Wahl, A.K.2    Hanestad, B.R.3
  • 98
    • 33748939434 scopus 로고    scopus 로고
    • Prevalence of musculoskeletal disorders is systematically higher in women than in men
    • Wijnjoven HAH, de Vet HCW, Picavet HSJ. Prevalence of musculoskeletal disorders is systematically higher in women than in men. Clin J Pain. 2006;22:717-724.
    • (2006) Clin J Pain , vol.22 , pp. 717-724
    • Wijnjoven, H.A.H.1    De Vet, H.C.W.2    Picavet, H.S.J.3
  • 99
    • 8644282176 scopus 로고    scopus 로고
    • Intimate partner violence and physical health consequences: Policy and practice implications
    • Plichta SB. Intimate partner violence and physical health consequences: policy and practice implications. J Interpers Violence. 2004;19:1296-1323.
    • (2004) J Interpers Violence , vol.19 , pp. 1296-1323
    • Plichta, S.B.1
  • 100
    • 33847796836 scopus 로고    scopus 로고
    • Cumulative interpersonal traumas and social support as risk and resiliency factors in predicting PTSD and depression among inner-city women
    • Schomm JA, Briggs-Phillips M, Hobfoll SE. Cumulative interpersonal traumas and social support as risk and resiliency factors in predicting PTSD and depression among inner-city women. J Trauma Stress. 2006;19:825-836.
    • (2006) J Trauma Stress , vol.19 , pp. 825-836
    • Schomm, J.A.1    Briggs-Phillips, M.2    Hobfoll, S.E.3
  • 101
    • 0034172668 scopus 로고    scopus 로고
    • Pain perception to the cold pressor test during the menstrual cycle in relation to estrogen levels and a comparison with men
    • Hellstrom B, Lundberg U. Pain perception to the cold pressor test during the menstrual cycle in relation to estrogen levels and a comparison with men. Integr Psychol Behav Sci. 2000;35:132-142.
    • (2000) Integr Psychol Behav Sci , vol.35 , pp. 132-142
    • Hellstrom, B.1    Lundberg, U.2
  • 102
    • 0041843703 scopus 로고    scopus 로고
    • Pain perception across the menstrual phases in women with chronic pain
    • Hellstrom B. Pain perception across the menstrual phases in women with chronic pain. Percept Motor Skills. 2003;96:201-211.
    • (2003) Percept Motor Skills , vol.96 , pp. 201-211
    • Hellstrom, B.1
  • 104
    • 0037230055 scopus 로고    scopus 로고
    • Serum allopregnanolone levels relate to FSFI score during the menstrual cycle
    • Nappi RE, Abbiati I, Luisi S, et al. Serum allopregnanolone levels relate to FSFI score during the menstrual cycle. J Sex Marital Ther. 2003;29:95-102.
    • (2003) J Sex Marital Ther , vol.29 , pp. 95-102
    • Nappi, R.E.1    Abbiati, I.2    Luisi, S.3
  • 105
    • 84055191662 scopus 로고    scopus 로고
    • Upregulation of neurosteroid biosynthesis as a pharmacological strategy to improve behavioral deficits in a putative mouse model of PTSD
    • Pinna G, Rasmusson AM. Upregulation of neurosteroid biosynthesis as a pharmacological strategy to improve behavioral deficits in a putative mouse model of PTSD. J Neuroendocrinology. 2012;24:102-116.
    • (2012) J Neuroendocrinology , vol.24 , pp. 102-116
    • Pinna, G.1    Rasmusson, A.M.2
  • 106
    • 84867058193 scopus 로고    scopus 로고
    • An fMRI study of unconditioned responses in post-traumatic stress disorder
    • Linman C, Zeffiro TA, Pitman RK, et al. An fMRI study of unconditioned responses in post-traumatic stress disorder. Biol Mood Anxiety Disord. 2011;1:8.
    • (2011) Biol Mood Anxiety Disord , vol.1 , pp. 8
    • Linman, C.1    Zeffiro, T.A.2    Pitman, R.K.3
  • 107
    • 33845988787 scopus 로고    scopus 로고
    • Altered pain processing in veterans with posttraumatic stress disorder
    • Geuze E, Westenberg GM, Jochims A, et al. Altered pain processing in veterans with posttraumatic stress disorder. Arch Gen Psychiatry. 2007;64:76-85.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 76-85
    • Geuze, E.1    Westenberg, G.M.2    Jochims, A.3
  • 108
    • 78650727969 scopus 로고    scopus 로고
    • Effects of trauma-related cues on pain processing in posttraumatic stress disorder: An fMRI investigation
    • Mickelborough MJS, Daniels JK, Coupland NJ, et al. Effects of trauma-related cues on pain processing in posttraumatic stress disorder: an fMRI investigation. J Psychiatry Neurosci. 2011;36:6-14.
    • (2011) J Psychiatry Neurosci , vol.36 , pp. 6-14
    • Mickelborough, M.J.S.1    Daniels, J.K.2    Coupland, N.J.3
  • 109
    • 49049101856 scopus 로고    scopus 로고
    • Quantitative testing of pain perception in subjects with PTSD - Implications for the mechanism of the coexistence between PTSD and chronic pain
    • Defrin R, Ginzburg K, Soloman Z, et al. Quantitative testing of pain perception in subjects with PTSD - implications for the mechanism of the coexistence between PTSD and chronic pain. Pain. 2008;138:450-459.
    • (2008) Pain , vol.138 , pp. 450-459
    • Defrin, R.1    Ginzburg, K.2    Soloman, Z.3
  • 110
    • 0142165203 scopus 로고    scopus 로고
    • Mood and anxiety disorders associated with chronic pain: An examination in a nationally representative sample
    • McWilliams LA, Cox BJ, Enns MW. Mood and anxiety disorders associated with chronic pain: an examination in a nationally representative sample. Pain. 2003;106:127-133.
    • (2003) Pain , vol.106 , pp. 127-133
    • McWilliams, L.A.1    Cox, B.J.2    Enns, M.W.3
  • 111
    • 0036742727 scopus 로고    scopus 로고
    • Chronic pain and psychopathology: Research findings and theoretical considerations
    • Dersh J, Polatin PB, Gatchel RJ. Chronic pain and psychopathology: research findings and theoretical considerations. Psychosom Med. 2002;64:773-786.
    • (2002) Psychosom Med , vol.64 , pp. 773-786
    • Dersh, J.1    Polatin, P.B.2    Gatchel, R.J.3
  • 112
    • 73349096872 scopus 로고    scopus 로고
    • Prevalence of chronic pain, posttraumatic stress disorder, and persistent postconcussive symptoms in OIF/OEF veterans: Polytrauma clinical triad
    • Lew HL, Otis JD, Tun C, et al. Prevalence of chronic pain, posttraumatic stress disorder, and persistent postconcussive symptoms in OIF/OEF veterans: polytrauma clinical triad. J Rehabil Res Dev. 2009;46:697-702.
    • (2009) J Rehabil Res Dev , vol.46 , pp. 697-702
    • Lew, H.L.1    Otis, J.D.2    Tun, C.3
  • 113
    • 21844485088 scopus 로고    scopus 로고
    • Explaining high rates of depression in chronic pain: A diathesis-stress framework
    • Banks SM, Kerns RD. Explaining high rates of depression in chronic pain: a diathesis-stress framework. Psychol Bull. 1996;119:95-110.
    • (1996) Psychol Bull , vol.119 , pp. 95-110
    • Banks, S.M.1    Kerns, R.D.2
  • 114
    • 18644367786 scopus 로고    scopus 로고
    • Traumatic brain injury in the war zone
    • Okie S. Traumatic brain injury in the war zone. N Engl J Med. 2005;352:2043-2047.
    • (2005) N Engl J Med , vol.352 , pp. 2043-2047
    • Okie, S.1
  • 115
    • 33748775183 scopus 로고    scopus 로고
    • Military TBI during the Iraq and Afghanistan wars
    • Warden D. Military TBI during the Iraq and Afghanistan wars. J Head Trauma Rehabil. 2006;21:398-402.
    • (2006) J Head Trauma Rehabil , vol.21 , pp. 398-402
    • Warden, D.1
  • 116
  • 117
    • 38749111066 scopus 로고    scopus 로고
    • Mild traumatic brain injury in US soldiers returning from Iraq
    • Hoge CW, McGurk D, Thomas JL, et al. Mild traumatic brain injury in US soldiers returning from Iraq. N Engl J Med. 2008;358:453-463.
    • (2008) N Engl J Med , vol.358 , pp. 453-463
    • Hoge, C.W.1    McGurk, D.2    Thomas, J.L.3
  • 118
    • 38049161830 scopus 로고    scopus 로고
    • PTSD and traumatic brain injury: Folklore and fact?
    • King NS. PTSD and traumatic brain injury: folklore and fact? Brain Inj. 2008;22:1-5.
    • (2008) Brain Inj , vol.22 , pp. 1-5
    • King, N.S.1
  • 119
    • 67649994616 scopus 로고    scopus 로고
    • Exploring the convergence of posttraumatic stress disorder and mild traumatic brain injury
    • Stein MB, McAllister TW. Exploring the convergence of posttraumatic stress disorder and mild traumatic brain injury. Am J Psychiatry. 2009;166:768-776.
    • (2009) Am J Psychiatry , vol.166 , pp. 768-776
    • Stein, M.B.1    McAllister, T.W.2
  • 120
    • 77957594741 scopus 로고    scopus 로고
    • Traumatic brain injury, posttraumatic stress disorder, and postconcussive symptoms reporting among troops returning from Iraq
    • Brenner LA, Ivins BJ, Schwab K, et al. Traumatic brain injury, posttraumatic stress disorder, and postconcussive symptoms reporting among troops returning from Iraq. J Head Trauma Rehabil. 2010;25:307-312.
    • (2010) J Head Trauma Rehabil , vol.25 , pp. 307-312
    • Brenner, L.A.1    Ivins, B.J.2    Schwab, K.3
  • 121
    • 67849097743 scopus 로고    scopus 로고
    • Progesterone as a neuroprotective factor in traumatic and ischemic brain injury
    • Sayeed I, Stein DG. Progesterone as a neuroprotective factor in traumatic and ischemic brain injury. Prog Brain Res. 2009;175:219-237.
    • (2009) Prog Brain Res , vol.175 , pp. 219-237
    • Sayeed, I.1    Stein, D.G.2
  • 122
    • 80052263533 scopus 로고    scopus 로고
    • Progesterone in the treatment of acute traumatic brain injury: A clinical perspective and update
    • Stein DG. Progesterone in the treatment of acute traumatic brain injury: a clinical perspective and update. Neuroscience. 2011;191:101-106.
    • (2011) Neuroscience , vol.191 , pp. 101-106
    • Stein, D.G.1
  • 123
    • 79952007497 scopus 로고    scopus 로고
    • Heightening of the stress response during the first weeks after a mild traumatic brain injury
    • Griesbach GS, Hovda DA, Tio DL, et al. Heightening of the stress response during the first weeks after a mild traumatic brain injury. Neuroscience. 2004;178:147-158.
    • (2004) Neuroscience , vol.178 , pp. 147-158
    • Griesbach, G.S.1    Hovda, D.A.2    Tio, D.L.3
  • 124
    • 84861647070 scopus 로고    scopus 로고
    • Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice
    • Asiedu MN, Mejia G, Ossipov MK, et al. Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice. J Pain. 2012;13:546-554.
    • (2012) J Pain , vol.13 , pp. 546-554
    • Asiedu, M.N.1    Mejia, G.2    Ossipov, M.K.3
  • 125
    • 79251578642 scopus 로고    scopus 로고
    • Exercise impacts brain-derived neurotorphic factor plasticity by engaging mechanisms of epigenetic regulation
    • Gomez-Piniella F, Zhuang Y, Feng J, et al. Exercise impacts brain-derived neurotorphic factor plasticity by engaging mechanisms of epigenetic regulation. Eur J Neurosci. 2011;33:383-390.
    • (2011) Eur J Neurosci , vol.33 , pp. 383-390
    • Gomez-Piniella, F.1    Zhuang, Y.2    Feng, J.3
  • 126
    • 80052265974 scopus 로고    scopus 로고
    • Effect of different exercise protocols on histone acetyltransferases and histone deacetylases activities in rat hippocampus
    • Elsner VR, Lovatel GA, Bertoldi K, et al. Effect of different exercise protocols on histone acetyltransferases and histone deacetylases activities in rat hippocampus. Neuroscience. 2011;192:580-587.
    • (2011) Neuroscience , vol.192 , pp. 580-587
    • Elsner, V.R.1    Lovatel, G.A.2    Bertoldi, K.3
  • 127
    • 84872410959 scopus 로고    scopus 로고
    • Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: A preliminary study
    • Elsner VR, Lovatel GA, Moyses F, et al. Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: a preliminary study. Exp Gerontol. 2013;48:136-139.
    • (2013) Exp Gerontol , vol.48 , pp. 136-139
    • Elsner, V.R.1    Lovatel, G.A.2    Moyses, F.3
  • 128
    • 18144386145 scopus 로고    scopus 로고
    • The impact of an exercise program on posttraumatic stress disorder, anxiety and depression
    • Manger TA, Motta RW. The impact of an exercise program on posttraumatic stress disorder, anxiety and depression. Int J Emerg Ment Health. 2005;7:49-57.
    • (2005) Int J Emerg Ment Health , vol.7 , pp. 49-57
    • Manger, T.A.1    Motta, R.W.2
  • 129
    • 84886194582 scopus 로고    scopus 로고
    • Physical activity and mental health
    • Tenenbaum G, Eklund RC, eds. Hoboken, NJ: Wiley & Sons
    • Landers DM, Arent SM. Physical activity and mental health. In: Tenenbaum G, Eklund RC, eds. Handbook of Sport Psychology. Hoboken, NJ: Wiley & Sons; 2007:469-491.
    • (2007) Handbook of Sport Psychology , pp. 469-491
    • Landers, D.M.1    Arent, S.M.2
  • 130
    • 84855609366 scopus 로고    scopus 로고
    • Cognitive behavior therapy, exercise, or both for treating chronic widespread pain
    • McBeth J, Prescott G, Scotland G, et al. Cognitive behavior therapy, exercise, or both for treating chronic widespread pain. Arch Intern Med. 2012;172:48-57.
    • (2012) Arch Intern Med , vol.172 , pp. 48-57
    • McBeth, J.1    Prescott, G.2    Scotland, G.3
  • 131
    • 33847412701 scopus 로고    scopus 로고
    • A pilot study of the effects of high-intensity aerobic exercise versus passive interventions on pain, disability, psychological strain and serum cortisol concentrations in people with chronic low back pain
    • Chatzitheodorou D, Kabitsis C, Malliou P, et al. A pilot study of the effects of high-intensity aerobic exercise versus passive interventions on pain, disability, psychological strain and serum cortisol concentrations in people with chronic low back pain. Phys Ther. 2007;87:304-312.
    • (2007) Phys Ther , vol.87 , pp. 304-312
    • Chatzitheodorou, D.1    Kabitsis, C.2    Malliou, P.3
  • 132
    • 0036069289 scopus 로고    scopus 로고
    • Exercise-induced hypoalgesia and intensity of exercise
    • Koltyn KF. Exercise-induced hypoalgesia and intensity of exercise. Sports Med. 2002;32:477-487.
    • (2002) Sports Med , vol.32 , pp. 477-487
    • Koltyn, K.F.1
  • 133
    • 84870240047 scopus 로고    scopus 로고
    • A meta-analytic review of the hypoalgesic effects of exercise
    • NaugleKM, Fillingim RB, Riley JL III. A meta-analytic review of the hypoalgesic effects of exercise. J Pain. 2012;13:1139-1150.
    • (2012) J Pain , vol.13 , pp. 1139-1150
    • Naugle, K.M.1    Fillingim, R.B.2    Riley, J.L.3
  • 134
    • 0022994944 scopus 로고
    • Plasma neuropeptide Y-like immunoreactivity and catecholamines during various degrees of sympathetic activation in man
    • Pernow J, Lundberg JM, Kaliser L, et al. Plasma neuropeptide Y-like immunoreactivity and catecholamines during various degrees of sympathetic activation in man. Clin Physiol. 1986;6:561-578.
    • (1986) Clin Physiol , vol.6 , pp. 561-578
    • Pernow, J.1    Lundberg, J.M.2    Kaliser, L.3
  • 135
    • 0032566848 scopus 로고    scopus 로고
    • Blood pressure, plasma NPY and catecholamines during physical exercise in relation to menstrual cycle, ovariectomy and estrogen replacement
    • Lewandowski J, Pruszczyk ME, Chodakowska J, et al. Blood pressure, plasma NPY and catecholamines during physical exercise in relation to menstrual cycle, ovariectomy and estrogen replacement. Regul Pept. 1998;75-76:239-245.
    • (1998) Regul Pept , vol.75-76 , pp. 239-245
    • Lewandowski, J.1    Pruszczyk, M.E.2    Chodakowska, J.3
  • 136
    • 0002436736 scopus 로고    scopus 로고
    • Neurosteroids and regulation of neuroendocrine function
    • Genazzani AR, Petaglia F, Purdy R II, eds. New York: The Parthenon
    • Genazzani AR, Salvestroni C, Guo AL, et al. Neurosteroids and regulation of neuroendocrine function. In: Genazzani AR, Petaglia F, Purdy R II, eds. The Brain: Source and Target for Sex Steroid Hormones. New York: The Parthenon; 1996:83-91.
    • (1996) The Brain: Source and Target for Sex Steroid Hormones , pp. 83-91
    • Genazzani, A.R.1    Salvestroni, C.2    Guo, A.L.3


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