-
1
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy
-
Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer. 2004; 4: 361-370
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
2
-
-
0037429725
-
The erbb receptors and their role in cancer progression
-
Holbro T, Civenni G, Hynes NE. The ErbB receptors and their role in cancer progression. Exp Cell Res. 2003; 284: 99-110
-
(2003)
Exp Cell Res
, vol.284
, pp. 99-110
-
-
Holbro, T.1
Civenni, G.2
Hynes, N.E.3
-
3
-
-
0037429737
-
Epidermal growth factor receptor: Mechanisms of activation and signalling
-
Jorissen RN, Walker F, Pouliot N, et al. Epidermal growth factor receptor: mechanisms of activation and signalling. Exp Cell Res. 2003; 284: 31-53
-
(2003)
Exp Cell Res
, vol.284
, pp. 31-53
-
-
Jorissen, R.N.1
Walker, F.2
Pouliot, N.3
-
4
-
-
0034788982
-
The erbb receptor tyrosine family as signal integrators
-
Hynes NE, Horsch K, Olayioye MA, et al. The ErbB receptor tyrosine family as signal integrators. Endocr Relat Cancer. 2001; 8: 151-159
-
(2001)
Endocr Relat Cancer
, vol.8
, pp. 151-159
-
-
Hynes, N.E.1
Horsch, K.2
Olayioye, M.A.3
-
5
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib. N Engl J Med. 2004; 350: 2129-2139
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
6
-
-
2342624080
-
Egfr mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004; 304: 1497-1500
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
7
-
-
4444344330
-
Egf receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA. 2004; 101: 13306-13311
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
8
-
-
38749114995
-
Oncogenes and cancer
-
Croce CM. Oncogenes and cancer. N Engl J Med. 2008; 358: 502-511
-
(2008)
N Engl J Med
, vol.358
, pp. 502-511
-
-
Croce, C.M.1
-
9
-
-
38049008135
-
Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of nonsmall-cell lung cancers
-
Savic S, Tapia C, Grilli B, et al. Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of nonsmall-cell lung cancers. Br J Cancer. 2008; 98: 154-160
-
(2008)
Br J Cancer
, vol.98
, pp. 154-160
-
-
Savic, S.1
Tapia, C.2
Grilli, B.3
-
10
-
-
33745965856
-
High sensitivity detection of epidermal growth factor receptor mutations in the pleural effusion of non-small cell lung cancer patients
-
Kimura H, Fujiwara Y, Sone T, et al. High sensitivity detection of epidermal growth factor receptor mutations in the pleural effusion of non-small cell lung cancer patients. Cancer Sci. 2006; 97: 642-648
-
(2006)
Cancer Sci
, vol.97
, pp. 642-648
-
-
Kimura, H.1
Fujiwara, Y.2
Sone, T.3
-
11
-
-
33644539850
-
Epidermal growth factor receptor gene mutation in non-small cell lung cancer using highly sensitive and fast taqman pcr assay
-
Endo K, Konishi A, Sasaki H, et al. Epidermal growth factor receptor gene mutation in non-small cell lung cancer using highly sensitive and fast TaqMan PCR assay. Lung Cancer. 2005; 50: 375-384
-
(2005)
Lung Cancer
, vol.50
, pp. 375-384
-
-
Endo, K.1
Konishi, A.2
Sasaki, H.3
-
12
-
-
20244389231
-
Somatic mutations of egfr gene in squamous cell carcinoma of the head and neck
-
Lee JW, Soung YH, Kim SY, et al. Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck. Clin Cancer Res. 2005; 11: 2879-2882
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2879-2882
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
-
13
-
-
33749606016
-
Usefulness of egfr mutation screening in pleural fluid to predict the clinical outcome of gefitinib treated patients with lung cancer
-
Soh J, Toyooka S, Aoe K, et al. Usefulness of EGFR mutation screening in pleural fluid to predict the clinical outcome of gefitinib treated patients with lung cancer. Int J Cancer. 2006; 119: 2353-2358
-
(2006)
Int J Cancer
, vol.119
, pp. 2353-2358
-
-
Soh, J.1
Toyooka, S.2
Aoe, K.3
-
14
-
-
73449096114
-
Frequency of and variables associated with the egfr mutation and its subtypes
-
Tanaka T, Matsuoka M, Sutani A, et al. Frequency of and variables associated with the EGFR mutation and its subtypes. Int J Cancer. 2010; 126: 651-655
-
(2010)
Int J Cancer
, vol.126
, pp. 651-655
-
-
Tanaka, T.1
Matsuoka, M.2
Sutani, A.3
-
15
-
-
80052588962
-
Identification of non-smallcell lung cancer with activating egfr mutations in malignant effusion and cerebrospinal fluid: Rapid and sensitive detection of exon 19 deletion e746-A750 and exon 21 l858r mutation by immunocytochemistry
-
Kawahara A, Azuma K, Sumi A, et al. Identification of non-smallcell lung cancer with activating EGFR mutations in malignant effusion and cerebrospinal fluid: rapid and sensitive detection of exon 19 deletion E746-A750 and exon 21 L858R mutation by immunocytochemistry. Lung Cancer. 2011; 74: 35-40
-
(2011)
Lung Cancer
, vol.74
, pp. 35-40
-
-
Kawahara, A.1
Azuma, K.2
Sumi, A.3
-
16
-
-
79952232123
-
Significance of epidermal growth factor receptor gene mutations in squamous cell lung carcinoma
-
Miyamae Y, Shimizu K, Hirato J, et al. Significance of epidermal growth factor receptor gene mutations in squamous cell lung carcinoma. Oncol Rep. 2011; 25: 921-928
-
(2011)
Oncol Rep
, vol.25
, pp. 921-928
-
-
Miyamae, Y.1
Shimizu, K.2
Hirato, J.3
-
17
-
-
79958114179
-
Detection of low-level egfr t790m mutation in lung cancer tissues
-
Oh JE, An CH, Yoo NJ, et al. Detection of low-level EGFR T790M mutation in lung cancer tissues. APMIS. 2011; 119: 403-411
-
(2011)
APMIS
, vol.119
, pp. 403-411
-
-
Oh, J.E.1
An, C.H.2
Yoo, N.J.3
-
18
-
-
79959340582
-
Antitumor effects of gefitinib for metastatic brain tumors from lung carcinomas with egfr mutation
-
Ono Y, Toyota Y, Toyoshima A, et al. Antitumor effects of gefitinib for metastatic brain tumors from lung carcinomas with EGFR mutation. No Shinkei Geka. 2011; 39: 569-574
-
(2011)
No Shinkei Geka
, vol.39
, pp. 569-574
-
-
Ono, Y.1
Toyota, Y.2
Toyoshima, A.3
-
19
-
-
84858337878
-
Detection of egfr mutation status in lung adenocarcinoma specimens with different proportions of tumor cells using two methods of differential sensitivity
-
Han HS, Lim SN, An JY, et al. Detection of EGFR mutation status in lung adenocarcinoma specimens with different proportions of tumor cells using two methods of differential sensitivity. J Thorac Oncol. 2012; 7: 355-364
-
(2012)
J Thorac Oncol
, vol.7
, pp. 355-364
-
-
Han, H.S.1
Lim, S.N.2
An, J.Y.3
-
20
-
-
84865530167
-
Direct comparison of 3 pcr methods in detecting egfr mutations in patients with advanced non-small-cell lung cancer
-
Ikeda T, Nakamura Y, Yamaguchi H, et al. Direct comparison of 3 PCR methods in detecting EGFR mutations in patients with advanced non-small-cell lung cancer. Clin Lung Cancer. 2012; 13: 369-374
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 369-374
-
-
Ikeda, T.1
Nakamura, Y.2
Yamaguchi, H.3
-
21
-
-
84866160573
-
A diagnostic algorithm using egfr mutation-specific antibodies for rapid response egfr-Tki treatment in patients with non-small cell lung cancer
-
Kawahara A, Taira T, Azuma K, et al. A diagnostic algorithm using EGFR mutation-specific antibodies for rapid response EGFR-TKI treatment in patients with non-small cell lung cancer. Lung Cancer. 2012; 78: 39-44
-
(2012)
Lung Cancer
, vol.78
, pp. 39-44
-
-
Kawahara, A.1
Taira, T.2
Azuma, K.3
-
22
-
-
84856585835
-
Detection and comparison of peptide nucleic acid-mediated real-Time polymerase chain reaction clamping and direct gene sequencing for epidermal growth factor receptor mutations in patients with non-small cell lung cancer
-
Kim HJ, Lee KY, Kim YC, et al. Detection and comparison of peptide nucleic acid-mediated real-Time polymerase chain reaction clamping and direct gene sequencing for epidermal growth factor receptor mutations in patients with non-small cell lung cancer. Lung Cancer. 2012; 75: 321-325
-
(2012)
Lung Cancer
, vol.75
, pp. 321-325
-
-
Kim, H.J.1
Lee, K.Y.2
Kim, Y.C.3
-
23
-
-
84861892217
-
The peptide nucleic acidlocked nucleic acid polymerase chain reaction clamp-based test for epidermal growth factor receptor mutations in bronchoscopic cytological specimens of non-small cell lung cancer
-
Yamada N, Oizumi S, Asahina H, et al. The Peptide nucleic Acidlocked nucleic Acid polymerase chain reaction clamp-based test for epidermal growth factor receptor mutations in bronchoscopic cytological specimens of non-small cell lung cancer. Oncology. 2012; 82: 341-346
-
(2012)
Oncology
, vol.82
, pp. 341-346
-
-
Yamada, N.1
Oizumi, S.2
Asahina, H.3
-
24
-
-
23844465454
-
Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid pcr clamp
-
Nagai Y, Miyazawa H, Huqun, et al. Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp. Cancer Res. 2005; 65: 7276-7282
-
(2005)
Cancer Res
, vol.65
, pp. 7276-7282
-
-
Nagai, Y.1
Miyazawa, H.H.2
-
25
-
-
31544459265
-
Detection of egfr gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay
-
Asano H, Toyooka S, Tokumo M, et al. Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay. Clin Cancer Res. 2006; 12: 43-48
-
(2006)
Clin Cancer Res
, vol.12
, pp. 43-48
-
-
Asano, H.1
Toyooka, S.2
Tokumo, M.3
-
26
-
-
33845572242
-
Evaluation of denaturing high-performance liquid chromatography as a rapid detection method for identification of epidermal growth factor receptor mutations in nonsmall-cell lung cancer
-
Cohen V, Agulnik JS, Jarry J, et al. Evaluation of denaturing high-performance liquid chromatography as a rapid detection method for identification of epidermal growth factor receptor mutations in nonsmall-cell lung cancer. Cancer. 2006; 107: 2858-2865
-
(2006)
Cancer
, vol.107
, pp. 2858-2865
-
-
Cohen, V.1
Agulnik, J.S.2
Jarry, J.3
-
27
-
-
32944468710
-
A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening
-
Janne PA, Borras AM, Kuang Y, et al. A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening. Clin Cancer Res. 2006; 12(pt 1): 751-758
-
(2006)
Clin Cancer Res
, vol.12
, Issue.PART 1
, pp. 751-758
-
-
Janne, P.A.1
Borras, A.M.2
Kuang, Y.3
-
28
-
-
84879456138
-
Comparison study of the performance of the qiagen egfr rgq and egfr pyro assays for mutation analysis in non-small cell lung cancer
-
Cushman-Vokoun AM, Crowley AM, Rapp SA, et al. Comparison study of the performance of the QIAGEN EGFR RGQ and EGFR pyro assays for mutation analysis in non-small cell lung cancer. Am J Clin Pathol. 2013; 140: 7-19
-
(2013)
Am J Clin Pathol
, vol.140
, pp. 7-19
-
-
Cushman-Vokoun, A.M.1
Crowley, A.M.2
Rapp, S.A.3
-
29
-
-
84875891467
-
Utility of serum dna and pyrosequencing for the detection of egfr mutations in non-small cell lung cancer
-
Akca H, Demiray A, Yaren A, et al. Utility of serum DNA and pyrosequencing for the detection of EGFR mutations in non-small cell lung cancer. Cancer Genet. 2013; 206: 73-80
-
(2013)
Cancer Genet
, vol.206
, pp. 73-80
-
-
Akca, H.1
Demiray, A.2
Yaren, A.3
-
30
-
-
84874972652
-
Comparison of direct sequencing, pna clamping-real time polymerase chain reaction, and pyrosequencing methods for the detection of egfr mutations in non-small cell lung carcinoma and the correlation with clinical responses to egfr tyrosine kinase inhibitor treatment
-
Lee HJ, Xu X, Kim H, et al. Comparison of direct sequencing, PNA clamping-real time polymerase chain reaction, and pyrosequencing methods for the detection of EGFR mutations in non-small cell lung carcinoma and the correlation with clinical responses to EGFR tyrosine kinase inhibitor treatment. Korean J Pathol. 2013; 47: 52-60
-
(2013)
Korean J Pathol
, vol.47
, pp. 52-60
-
-
Lee, H.J.1
Xu, X.2
Kim, H.3
-
31
-
-
33749340253
-
Detection of egfr mutations in archived cytologic specimens of non-small cell lung cancer using high-resolution melting analysis
-
Nomoto K, Tsuta K, Takano T, et al. Detection of EGFR mutations in archived cytologic specimens of non-small cell lung cancer using high-resolution melting analysis. Am J Clin Pathol. 2006; 126: 608-615
-
(2006)
Am J Clin Pathol
, vol.126
, pp. 608-615
-
-
Nomoto, K.1
Tsuta, K.2
Takano, T.3
-
32
-
-
58949091382
-
An alternative method for screening egfr mutation using rflp in non-small cell lung cancer patients
-
Kawada I, Soejima K, Watanabe H, et al. An alternative method for screening EGFR mutation using RFLP in non-small cell lung cancer patients. J Thorac Oncol. 2008; 3: 1096-1103
-
(2008)
J Thorac Oncol
, vol.3
, pp. 1096-1103
-
-
Kawada, I.1
Soejima, K.2
Watanabe, H.3
-
33
-
-
63449103435
-
Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital pcr in non-small cell lung cancer patients
-
Yung TK, Chan KC, Mok TS, et al. Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients. Clin Cancer Res. 2009; 15: 2076-2084
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2076-2084
-
-
Yung, T.K.1
Chan, K.C.2
Mok, T.S.3
-
34
-
-
65549153120
-
Cold-pcr: A new platform for highly improved mutation detection in cancer and genetic testing
-
Li J, Makrigiorgos GM. COLD-PCR: a new platform for highly improved mutation detection in cancer and genetic testing. Biochem Soc Trans. 2009; 37(Pt 2): 427-432
-
(2009)
Biochem Soc Trans
, vol.37
, Issue.PART 2
, pp. 427-432
-
-
Li, J.1
Makrigiorgos, G.M.2
-
35
-
-
84857687561
-
Competitive amplification of differentially melting amplicons (cadma) enables sensitive and direct detection of all mutation types by highresolution melting analysis
-
Kristensen LS, Andersen GB, Hager H, et al. Competitive amplification of differentially melting amplicons (CADMA) enables sensitive and direct detection of all mutation types by highresolution melting analysis. Hum Mutat. 2012; 33: 264-271
-
(2012)
Hum Mutat
, vol.33
, pp. 264-271
-
-
Kristensen, L.S.1
Andersen, G.B.2
Hager, H.3
-
36
-
-
84925859574
-
Prospective evaluation of first-line tyrosine kinase inhibition with erlotinib in patients with advanced non-small cell lung cancer (nsclc) harbouring a mutant egfr gene (fielt study
-
De Grève JL, Van Meerbeeck J, Vansteenkiste J, et al. Prospective evaluation of first-line tyrosine kinase inhibition with erlotinib in patients with advanced non-small cell lung cancer (NSCLC) harbouring a mutant EGFR gene (FIELT study). J Thorac Oncol. 2007; 2: S712
-
(2007)
J Thorac Oncol
, vol.2
, pp. S712
-
-
De Grève, J.L.1
Van Meerbeeck, J.2
Vansteenkiste, J.3
-
37
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R, Moran T, Queralt C, et al. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med. 2009; 361: 958-967
-
(2009)
N Engl J Med
, vol.361
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
-
38
-
-
33847323129
-
Epidermal growth factor receptor mutations in lung cancer
-
Sharma SV, Bell DW, Settleman J, et al. Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer. 2007; 7: 169-181
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 169-181
-
-
Sharma, S.V.1
Bell, D.W.2
Settleman, J.3
-
39
-
-
3843084078
-
The cosmic (catalogue of somatic mutations in cancer) database and website
-
Bamford S, Dawson E, Forbes S, et al. The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer. 2004; 91: 355-358
-
(2004)
Br J Cancer
, vol.91
, pp. 355-358
-
-
Bamford, S.1
Dawson, E.2
Forbes, S.3
|