Rapid sensitive validated UPLC-MS method for determination of venlafaxine and its metabolite in rat plasma: Application to pharmacokinetic study

Journal of Pharmaceutical Analysis

Volumn 3, Issue 6, 2013, Pages 466-471

  Dubey, Sunil Kumar ^a   Saha, R N ^a   Jangala, Hemanth ^a   Pasha, S ^b  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^b CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

Metabolite; O desmethylvenlafaxine; UPLC MS ES; Venlafaxine

Indexed keywords

DESVENLAFAXINE; DRUG METABOLITE; VENLAFAXINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA CLEARANCE; PLASMA CONCENTRATION-TIME CURVE; RAT; SOLID PHASE EXTRACTION; STANDARD; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

RATTUS;

EID: 84925835378     PISSN: 20951779     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpha.2013.05.002     Document Type: Article

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