Clinical characteristics and circumstances of death in the sudden arrhythmic death syndrome

Circulation: Arrhythmia and Electrophysiology

Volumn 7, Issue 6, 2014, Pages 1078-1083

  Mellor, Greg ^a   Raju, Hariharan ^a   De Noronha, Sofia V ^a   Papadakis, Michael ^a   Sharma, Sanjay ^a   Behr, Elijah R ^a   Sheppard, Mary N ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Epilepsy; Postmortem; Sudden cardiac death

Indexed keywords

ADULT; ARTICLE; AUTOPSY; CAUSE OF DEATH; CLINICAL EVALUATION; CLINICAL FEATURE; EMOTIONAL STRESS; EPILEPSY; EXERCISE; FAINTNESS; FAMILY HISTORY; FEMALE; HEART ARRHYTHMIA; HEART ATRIOVENTRICULAR NODE; HEART ATRIUM FIBRILLATION; HEART LEFT BUNDLE BRANCH BLOCK; HEART MUSCLE CONDUCTION DISTURBANCE; HEART VENTRICLE TACHYCARDIA; HISTOPATHOLOGY; HUMAN; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REST; RISK ASSESSMENT; SLEEP; SUDDEN CARDIAC DEATH; SUPRAVENTRICULAR TACHYCARDIA; UNITED KINGDOM; ADOLESCENT; AGE; ARRHYTHMIAS, CARDIAC; CHILD; COMORBIDITY; COMPLICATION; DEATH, SUDDEN, CARDIAC; EPIDEMIOLOGY; GENETIC PREDISPOSITION; GENETICS; GREAT BRITAIN; HEREDITY; INFANT; MORTALITY; PEDIGREE; PRESCHOOL CHILD; RETROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; TERTIARY CARE CENTER; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; ARRHYTHMIAS, CARDIAC; CHILD; CHILD, PRESCHOOL; COMORBIDITY; DEATH, SUDDEN, CARDIAC; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GREAT BRITAIN; HEREDITY; HUMANS; INFANT; MALE; PEDIGREE; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SEX FACTORS; TERTIARY CARE CENTERS; YOUNG ADULT;

EID: 84925714472     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/CIRCEP.114.001854     Document Type: Article

References (33)

1. Winkel BG, Holst AG, Theilade J, Kristensen IB, Thomsen JL, Ottesen GL, Bundgaard H, Svendsen JH, Haunsø S, Tfelt-Hansen J. Nationwide study of sudden cardiac death in persons aged 1-35 years. Eur Heart J. 2011;32:983-990.
2. Morentin B, Suárez-Mier MP, Aguilera B. Sudden unexplained death among persons 1-35 years old. Forensic Sci Int. 2003;135:213-217.
3. Puranik R, Chow CK, Duflou JA, Kilborn MJ, McGuire MA. Sudden death in the young. Heart Rhythm. 2005;2:1277-1282.
4. Reddy PR, Reinier K, Singh T, Mariani R, Gunson K, Jui J, Chugh SS. Physical activity as a trigger of sudden cardiac arrest: the Oregon Sudden Unexpected Death Study. Int J Cardiol. 2009;131:345-349.
5. Doolan A, Langlois N, Semsarian C. Causes of sudden cardiac death in young Australians. Med J Aust. 2004;180:110-112.
6. Margey R, Roy A, Tobin S, O'Keane CJ, McGorrian C, Morris V, Jennings S, Galvin J. Sudden cardiac death in 14- to 35-year olds in Ireland from 2005 to 2007: a retrospective registry. Europace. 2011;13:1411-1418.
7. Corrado D, Basso C, Thiene G. Sudden cardiac death in young people with apparently normal heart. Cardiovasc Res. 2001;50:399-408.
8. Papadakis M, Sharma S, Cox S, Sheppard MN, Panoulas VF, Behr ER. The magnitude of sudden cardiac death in the young: a death certificatebased review in England and Wales. Europace. 2009;11:1353-1358.
9. Fabre A, Sheppard MN. Sudden adult death syndrome and other non- ischaemic causes of sudden cardiac death. Heart. 2006;92:316-320.
10. Maron BJ, Doerer JJ, Haas TS, Tierney DM, Mueller FO. Sudden deaths in young competitive athletes: analysis of 1866 deaths in the United States, 1980-2006. Circulation. 2009;119:1085-1092.
11. de Noronha SV, Sharma S, Papadakis M, Desai S, Whyte G, Sheppard MN. Aetiology of sudden cardiac death in athletes in the United Kingdom: a pathological study. Heart. 2009;95:1409-1414.
12. Behr ER, Dalageorgou C, Christiansen M, Syrris P, Hughes S, Tome Esteban MT, Rowland E, Jeffery S, McKenna WJ. Sudden arrhythmic death syndrome: familial evaluation identifies inheritable heart disease in the majority of families. Eur Heart J. 2008;29:1670-1680.
13. Tan HL, Hofman N, van Langen IM, van der Wal AC, Wilde AA. Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives. Circulation. 2005;112:207-213.
14. Ministry of Justice. Coroners Statistics 2011 England and Wales. 2012.
15. Hoyert DL. The changing profile of autopsied deaths in the United States, 1972-2007. NCHS Data Brief. 2011;67:1-8.
16. Kapusta ND, Tran US, Rockett IR, De Leo D, Naylor CP, Niederkrotenthaler T, Voracek M, Etzersdorfer E, Sonneck G. Declining autopsy rates and suicide misclassification: a cross-national analysis of 35 countries. Arch Gen Psychiatry. 2011;68:1050-1057.
17. Wong LCH, Behr ER. Sudden unexplained death in infants and children: the role of undiagnosed inherited cardiac conditions. Europace. 2014. In press. doi 10.1093/europace/euu037.
18. Basso C, Burke M, Fornes P, Gallagher PJ, de Gouveia RH, Sheppard M, Thiene G, van der Wal A; Association for European Cardiovascular Pathology. Guidelines for autopsy investigation of sudden cardiac death. Virchows Arch. 2008;452:11-18.
19. Sheppard MN. Approach to the cardiac autopsy. J Clin Pathol. 2012;65:484-495.
20. de Noronha SV, Behr ER, Papadakis M, Ohta-Ogo K, Banya W, Wells J, Cox S, Cox A, Sharma S, Sheppard MN. The importance of specialist cardiac histopathological examination in the investigation of young sudden cardiac deaths. Europace. 2014;16:899-907.
21. Papadakis M, Raju H, Behr ER, De Noronha SV, Spath N, Kouloubinis A, Sheppard MN, Sharma S. Sudden cardiac death with autopsy findings of uncertain significance: potential for erroneous interpretation. Circ Arrhythm Electrophysiol. 2013;6:588-596.
22. Matsuo K, Kurita T, Inagaki M, Kakishita M, Aihara N, Shimizu W, Taguchi A, Suyama K, Kamakura S, Shimomura K. The circadian pattern of the development of ventricular fibrillation in patients with Brugada syndrome. Eur Heart J. 1999;20:465-470.
23. Tester DJ, Medeiros-Domingo A, Will ML, Haglund CM, Ackerman MJ. Cardiac channel molecular autopsy: insights from 173 consecutive cases of autopsy-negative sudden unexplained death referred for postmortem genetic testing. Mayo Clin Proc. 2012;87:524-539.
24. Priori SG. Clinical and Molecular Characterization of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation. 2002;106:69-74.
25. Priori SG, Wilde A, Horie M, Cho Y, Behr ER, Berul C, Blom N, Brugada J, Chiang C-E, Huikuri H, Kannankeril P, Krahn A, Leenhardt A, Moss A, Schwartz PJ, Shimizu W, Tomaselli G, Tracy C. Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes. Europace. 2013;15:1389-1406.
26. Health and Social Care Commision. National Audit of Sudden Arrhythmic Death Syndrome 2012.
27. Behr ER, Casey A, Sheppard M, Wright M, Bowker TJ, Davies MJ, McKenna WJ, Wood DA. Sudden arrhythmic death syndrome: a national survey of sudden unexplained cardiac death. Heart. 2007;93:601-605.
28. MacDonald BK, Cockerell OC, Sander JW, Shorvon SD. The incidence and lifetime prevalence of neurological disorders in a prospective community- based study in the UK. Brain. 2000;123 (Pt 4):665-676.
29. Ficker DM, So EL, Shen WK, Annegers JF, O'Brien PC, Cascino GD, Belau PG. Population-based study of the incidence of sudden unexplained death in epilepsy. Neurology. 1998;51:1270-1274.
30. Shorvon S, Tomson T. Sudden unexpected death in epilepsy. Lancet. 2011;378:2028-2038.
31. Hesdorffer DC, Tomson T, Benn E, Sander JW, Nilsson L, Langan Y, Walczak TS, Beghi E, Brodie MJ, Hauser A; ILAE Commission on Epidemiology; Subcommission on Mortality. Combined analysis of risk factors for SUDEP. Epilepsia. 2011;52:1150-1159.
32. Stecker EC, Reinier K, Uy-Evanado A, Teodorescu C, Chugh H, Gunson K, Jui J, Chugh SS. Relationship between seizure episode and sudden cardiac arrest in patients with epilepsy: a community-based study. Circ Arrhythm Electrophysiol. 2013;6:912-916.
33. Zaidi A, Clough P, Cooper P, Scheepers B, Fitzpatrick AP. Misdiagnosis of epilepsy: many seizure-like attacks have a cardiovascular cause. J Am Coll Cardiol. 2000;36:181-184.