Emotional learning selectively and retroactively strengthens memories for related events

Nature

Volumn 520, Issue 7547, 2015, Pages 345-348

  Dunsmoor, Joseph E ^a   Murty, Vishnu P ^a   Davachi, Lila ^a   Phelps, Elizabeth A ^a,b  

^a NEW YORK UNIVERSITY   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPISODIC EVENT; LEARNING; MEMORY; NEUROLOGY;

ADULT; ARTICLE; CONDITIONING; CONTROLLED STUDY; ELECTRIC SHOCK; EMOTION; EMOTIONAL LEARNING; EPISODIC MEMORY; FEAR; FEMALE; FOLLOW UP; HUMAN; LEARNING; LONG TERM MEMORY; LONG TERM POTENTIATION; MAJOR CLINICAL STUDY; MALE; MEMORY; MEMORY CONSOLIDATION; PERSONAL EXPERIENCE; PRIORITY JOURNAL; RECOGNITION; SHORT TERM MEMORY; BIOLOGICAL MODEL; CONDITIONED REFLEX; NERVE TRACT; PHOTOSTIMULATION; PHYSIOLOGY; PSYCHOLOGY; RECALL; TIME FACTOR; YOUNG ADULT;

RODENTIA;

CONDITIONING, CLASSICAL; EMOTIONS; FEAR; FEMALE; HUMANS; MALE; MEMORY, EPISODIC; MEMORY, LONG-TERM; MEMORY, SHORT-TERM; MENTAL RECALL; MODELS, NEUROLOGICAL; NEURAL PATHWAYS; PHOTIC STIMULATION; RECOGNITION (PSYCHOLOGY); TIME FACTORS; YOUNG ADULT;

EID: 84925660559     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14106     Document Type: Article

References (25)

1. Frey, U. & Morris, R. G. Synaptic tagging and long-term potentiation. Nature 385, 533-536 (1997).
2. Ballarini, F., Moncada, D., Martinez, M. C., Alen, N. & Viola, H. Behavioral tagging is a general mechanism of long-term memory formation. Proc. Natl Acad. Sci. USA 106, 14599-14604 (2009).
3. de Carvalho Myskiw, J., Benetti, F. & Izquierdo, I. Behavioral tagging of extinction learning. Proc. Natl Acad. Sci. USA 110, 1071-1076 (2013).
4. LaBar, K. S. & Cabeza, R. Cognitive neuroscience of emotional memory. Nature Rev. Neurosci. 7, 54-64 (2006).
5. Lisman, J., Grace, A. A. & Duzel, E. A neoHebbian framework for episodic memory; role of dopamine-dependent late LTP. Trends Neurosci. 34, 536-547 (2011).
6. Wang, S. H., Redondo, R. L. & Morris, R. G. Relevance of synaptic tagging and capture to the persistence of long-term potentiation and everyday spatial memory. Proc. Natl Acad. Sci. USA 107, 19537-19542 (2010).
7. Moncada, D. & Viola, H. Induction of long-term memory by exposure to novelty requires protein synthesis: evidence for a behavioral tagging. J. Neurosci. 27, 7476-7481 (2007).
8. McGaugh, J. L. The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annu. Rev. Neurosci. 27, 1-28 (2004).
9. Cahill, L. & McGaugh, J. L. Mechanisms of emotional arousal and lasting declarative memory. Trends Neurosci. 21, 294-299 (1998).
10. Moncada, D., Ballarini, F., Martinez, M. C., Frey, J. U. & Viola, H. Identification of transmitter systems and learning tag molecules involved in behavioral tagging during memory formation. Proc. Natl Acad. Sci. USA 108, 12931-12936 (2011).
11. da Silva, B. M., Bast, T. & Morris, R. G. Spatial memory: behavioral determinants of persistence in the watermaze delayed matching-to-place task. Learn. Mem. 21, 28-36 (2014).
12. Dunsmoor, J. E., Martin, A. & LaBar, K. S. Role of conceptual knowledge in learning and retention of conditioned fear. Biol. Psychol. 89, 300-305 (2012).
13. Dunsmoor, J. E., Kragel, P. A., Martin, A. & LaBar, K. S. Aversive learning modulates cortical representations of object categories. Cereb. Cortex 24, 2859-2872(2014).
14. Martin, A. The representation of object concepts in the brain. Annu. Rev. Psychol. 58, 25-45 (2007).
15. Stickgold, R. & Walker, M. P. Sleep-dependent memory triage: evolving generalization through selective processing. Nature Neurosci. 16, 139-145 (2013).
16. Park, J. Effect of arousal and retention delay on memory: a meta-analysis. Psychol. Rep. 97, 339-355 (2005).
17. Kleinsmith, L. J.& Kaplan, S. Paired-associate learning as a function of arousal and interpolated interval. J. Exp. Psychol. 65, 190-193 (1963).
18. Wilhelm, I. et al. Sleep selectively enhances memory expected to be of future relevance. J. Neurosci. 31, 1563-1569 (2011).
19. van Dongen, E. V., Thielen, J. W., Takashima, A., Barth, M. & Fernandez, G. Sleep supports selective retention of associativememories based on relevance for future utilization. PLoS ONE 7, e43426 (2012).
20. Shohamy, D. & Wagner, A. D. Integrating memories in the human brain: hippocampal-midbrain encoding of overlapping events. Neuron 60, 378-389 (2008).
21. Ellenbogen, J. M., Hu, P. T., Payne, J. D., Titone, D. & Walker, M. P. Human relational memory requires time and sleep. Proc. Natl Acad. Sci. USA 104, 7723-7728 (2007).
22. Lakens, D. Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. Front. Psychol. 4, 863 (2013).
23. Schiller, D. et al. Preventing the return of fear in humans using reconsolidation update mechanisms. Nature 463, 49-53 (2010).
24. Dunsmoor, J. E., Mitroff, S. R. & LaBar, K. S. Generalization of conditioned fear along a dimension of increasing fear intensity. Learn. Mem. 16, 460-469 (2009).
25. Green, S. R., Kragel, P. A., Fecteau, M. E. & LaBar, K. S. Development and validation of an unsupervised scoring system(Autonomate) for skin conductance response analysis. Int. J. Psychophysiol. 91, 186-193 (2014).