IL-10, IL-15, IL-17, and GMCSF levels in cervical cancer tissue of Tanzanian women infected with HPV16/18 vs. non-HPV16/18 genotypes Clinical oncology

Infectious Agents and Cancer

Volumn 10, Issue 1, 2015, Pages

  Vidal, Adriana C ^a   Skaar, David ^b   Maguire, Rachel ^b   Dodor, Seyram ^b   Musselwhite, Laura W ^c   Bartlett, John A ^d   Oneko, Olola ^e   Obure, Joseph ^e   Mlay, Pendo ^e   Murphy, Susan K ^d   Hoyo, Cathrine ^b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e KILIMANJARO CHRISTIAN MEDICAL CENTRE   (Tanzania)

Author keywords

Case only; Cytokines; Disparities; HPV infection; Invasive cervical cancer; Race

Indexed keywords

ALPHA INTERFERON; CHEMOKINE; COLONY STIMULATING FACTOR 1; CYTOKINE; FIBROBLAST GROWTH FACTOR 12; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADULT; AGE; ARTICLE; CANCER PATIENT; CANCER RISK; CANCER TISSUE; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTRACEPTIVE BEHAVIOR; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENOTYPE; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; HUMAN TISSUE; MIDDLE AGED; PAPILLOMAVIRUS INFECTION; PARITY; PRIORITY JOURNAL; QUESTIONNAIRE; RISK FACTOR; SMOKING; TANZANIAN; TUMOR INVASION; UTERINE CERVIX CANCER;

EID: 84925654368     PISSN: None     EISSN: 17509378     Source Type: Journal    
DOI: 10.1186/s13027-015-0005-1     Document Type: Article

References (26)

1. Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin. 2014;64(1):9-29.
2. Singh GK, Miller BA, Hankey BF, Edwards BK. Persistent area socioeconomic disparities in U.S. incidence of cervical cancer, mortality, stage, and survival, 1975-2000. Cancer. 2004;101(5):1051-7.
3. Coughlin SS, King J, Richards TB, Ekwueme DU. Cervical cancer screening among women in metropolitan areas of the United States by individual-level and area-based measures of socioeconomic status, 2000 to. Cancer Epidemiol Biomarkers Prev. 2002;15(11):2154-9.
4. Simard EP, Fedewa S, Ma J, Siegel R, Jemal A. Widening socioeconomic disparities in cervical cancer mortality among women in 26 states, 1993-2007. Cancer. 2012;118(20):5110-6.
5. Hariri S, Unger ER, Powell SE, Bauer HM, Bennett NM, Bloch KC, et al. Human papillomavirus genotypes in high-grade cervical lesions in the United States. J Infect Dis. 2012;206(12):1878-86.
6. Niccolai LM, Russ C, Julian PJ, Hariri S, Sinard J, Meek JI, et al. Individual and geographic disparities in human papillomavirus types 16/18 in high-grade cervical lesions: Associations with race, ethnicity, and poverty. Cancer. 2013;119(16):3052-8.
7. Vidal AC, Smith JS, Valea F, Bentley R, Gradison M, Yarnall KS, et al. HPV genotypes and cervical intraepithelial neoplasia in a multiethnic cohort in the southeastern USA. Cancer Causes Control. 2014;25(8):1055-62.
8. Vidal AC, Murphy SK, Hernandez BY, Vasquez B, Bartlett JA, Oneko O, et al. Distribution of HPV genotypes in cervical intraepithelial lesions and cervical cancer in Tanzanian women. Infect Agent Cancer. 2011;6(1):20.
9. Banister CE, Messersmith AR, Cai B, Spiryda LB, Glover SH, Pirisi L, et al. Disparity in the persistence of high-risk human papillomavirus genotypes between African American and European American Women of College Age. J Infect Dis. 2014;211:100-8.
10. Feng Q, Wei H, Morihara J, Stern J, Yu M, Kiviat N, et al. Th2 type inflammation promotes the gradual progression of HPV-infected cervical cells to cervical carcinoma. Gynecol Oncol. 2012;127(2):412-9.
11. Paradkar PH, Joshi JV, Mertia PN, Agashe SV, Vaidya RA. Role of cytokines in genesis, progression and prognosis of cervical cancer. Asian Pac J Cancer Prev. 2014;15(9):3851-64.
12. Ouyang W, Rutz S, Crellin NK, Valdez PA, Hymowitz SG. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol. 2011;29:71-109.
13. Azar KK, Tani M, Yasuda H, Sakai A, Inoue M, Sasagawa T. Increased secretion patterns of interleukin-10 and tumor necrosis factor-alpha in cervical squamous intraepithelial lesions. Hum Pathol. 2004;35(11):1376-84.
14. Clerici M, Merola M, Ferrario E, Trabattoni D, Villa ML, Stefanon B, et al. Cytokine production patterns in cervical intraepithelial neoplasia: association with human papillomavirus infection. J Natl Cancer Inst. 1997;89(3):245-50.
15. Mindiola R, Caulejas D, Nunez-Troconis J, Araujo M, Delgado M, Mosquera J. Increased number of IL-2, IL-2 receptor and IL-10 positive cells in premalignant lesions of the cervix. Invest Clin. 2008;49(4):533-45.
16. Scott ME, Shvetsov YB, Thompson PJ, Hernandez BY, Zhu X, Wilkens LR, et al. Cervical cytokines and clearance of incident human papillomavirus infection: Hawaii HPV cohort study. Int J Cancer. 2013;133(5):1187-96.
17. Vidal AC, Henry NM, Murphy SK, Oneko O, Nye M, Bartlett JA, et al. PEG1/MEST and IGF2 DNA methylation in CIN and in cervical cancer. Clin Transl Oncol. 2014;16(3):266-72.
18. Apgar BS, Zoschnick L, Wright Jr TC. The 2001 Bethesda System terminology. Am Fam Physician. 2003;68(10):1992-8.
19. Gravitt PE, Peyton CL, Alessi TQ, Wheeler CM, Coutlee F, Hildesheim A, et al. Improved amplification of genital human papillomaviruses. J Clin Microbiol. 2000;38(1):357-61.
20. Gravitt PE, Peyton CL, Apple RJ, Wheeler CM. Genotyping of 27 human papillomavirus types by using L1 consensus PCR products by a single-hybridization, reverse line blot detection method. J Clin Microbiol. 1998;36(10):3020-7.
21. Qi L, Nassir R, Kosoy R, Garcia L, Waetjen LE, Ochs-Balcom HM, et al. Relationship between hysterectomy and admixture in African American women. Am J Obstet Gynecol. 2013;208(4):279.e271-277.
22. Yu Q, Lou XM, He Y. Prediction of local recurrence in cervical cancer by a Cox model comprised of lymph node status, lymph-vascular space invasion, and intratumoral Th17 cell-infiltration. Med Oncol. 2014;31(1):795.
23. Gosmann C, Mattarollo SR, Bridge JA, Frazer IH, Blumenthal A. IL-17 Suppresses Immune Effector Functions in Human Papillomavirus-Associated Epithelial Hyperplasia. J Immunol. 2014;193(5):2248-57.
24. Wang Y, Liu XH, Li YH, Li O. The paradox of IL-10-mediated modulation in cervical cancer. Biomed Rep. 2013;1(3):347-51.
25. Scott ME, Ma Y, Kuzmich L, Moscicki AB. Diminished IFN-gamma and IL-10 and elevated Foxp3 mRNA expression in the cervix are associated with CIN 2 or 3. Int J Cancer. 2009;124(6):1379-83.
26. Syrjanen S, Naud P, Sarian L, Derchain S, Roteli-Martins C, Longatto-Filho A, et al. Immunosuppressive cytokine Interleukin-10 (IL-10) is up-regulated in high-grade CIN but not associated with high-risk human papillomavirus (HPV) at baseline, outcomes of HR-HPV infections or incident CIN in the LAMS cohort. Virchows Arch. 2009;455(6):505-15.