Angiotensin II type 1 receptor antibody precipitating acute vascular rejection in kidney transplantation

Nephrology

Volumn 20, Issue S1, 2015, Pages 10-12

  Jobert, Anjelo ^a   Rao, Nitesh ^a   Deayton, Sue ^b   Bennett, Greg D ^b   Brealey, John ^c   Nolan, James ^c   Carroll, Robert P ^a   Dragun, Duska ^d   Coates, Patrick T ^a  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b AUSTRALIAN RED CROSS BLOOD SERVICE   (Australia)

^c SA PATHOLOGY   (Australia)

^d DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

atypical antibody; non HLA antibodies; rejection; vascular

Indexed keywords

ANGIOTENSIN II TYPE 1 RECEPTOR ANTIBODY; BASILIXIMAB; CANDESARTAN; CREATININE; FRESH FROZEN PLASMA; HLA ANTIBODY; HLA ANTIGEN; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; TACROLIMUS; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG; AGTR1 PROTEIN, HUMAN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; AUTOANTIBODY; BENZIMIDAZOLE DERIVATIVE; CORTICOSTEROID; IMMUNOSUPPRESSIVE AGENT; LYMPHOCYTE ANTIBODY; TETRAZOLE DERIVATIVE;

ACUTE VASCULAR REJECTION; ADULT; CASE REPORT; COLD ISCHEMIA; CORTICOSTEROID THERAPY; CREATININE BLOOD LEVEL; CYTOMEGALOVIRUS; DRUG BLOOD LEVEL; END STAGE RENAL DISEASE; EPSTEIN BARR VIRUS; FOLLOW UP; GRAFT RECIPIENT; HUMAN; HYPERTENSION; KIDNEY ALLOGRAFT; KIDNEY BIOPSY; MALE; PERITONEAL DIALYSIS; PLASMAPHERESIS; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY; REVIEW; ACUTE DISEASE; ADVERSE EFFECTS; ALLOGRAFT; BIOPSY; BLOOD; DRUG EFFECTS; DRUG PULSE THERAPY; GRAFT REJECTION; IMMUNOLOGY; KIDNEY TRANSPLANTATION; ORAL DRUG ADMINISTRATION; SEVERITY OF ILLNESS INDEX; TIME; TREATMENT OUTCOME; UPREGULATION;

ACUTE DISEASE; ADMINISTRATION, ORAL; ADRENAL CORTEX HORMONES; ADULT; ALLOGRAFTS; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANTILYMPHOCYTE SERUM; AUTOANTIBODIES; BENZIMIDAZOLES; BIOPSY; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; PLASMA EXCHANGE; PULSE THERAPY, DRUG; RECEPTOR, ANGIOTENSIN, TYPE 1; SEVERITY OF ILLNESS INDEX; TETRAZOLES; TIME FACTORS; TREATMENT OUTCOME; UP-REGULATION;

EID: 84925629773     PISSN: 13205358     EISSN: 14401797     Source Type: Journal    
DOI: 10.1111/nep.12421     Document Type: Review

References (8)

1. Dragun D, Philippe A, Catar R,. Role of non-HLA antibodies in organ transplantation. Curr. Opin. Organ. Transplant. 2012; 17 (4): 440-445. doi: 10.1097/MOT.0b013e328355f12b.
2. Dragun D, Muller DN, Brasen JH, et al. Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N. Engl. J. Med. 2005; 352: 558-569.
3. Taniguchi M, Rebellato LM, Cai J, et al. Higher risk of kidney graft failure in the presence of anti-angiotensin II type 1 receptor antibodies. Am. J. Transplant. 2013; 13: 2577-2589.
4. Haas M, Sis B, Racusen LC, et al. Banff 2013 meeting report: Inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions. Am. J. Transplant. 2014; 14 (2): 272-283. doi: 10.1111/ajt.12590.
5. Wenzel K, Rajakumar A, Haase H, et al. Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats. Hypertension 2011; 58 (1): 77-84.
6. Giral M, Foucher Y, Dufay A, et al. Pretransplant sensitization against angiotensin II type 1 receptor is a risk factor for acute rejection and graft loss. Am. J. Transplant. 2013; 13: 2567-2576.
7. Amico P, Honger G, Bielmann D, et al. Incidence and prediction of early antibody-mediated rejection due to non-human leukocyte antigen-antibodies. Transplantation 2008; 85: 1557-1563.
8. Reinsmoen NL, Lai CH, Heidecke H, et al. Anti-angiotensin type 1 receptor antibodies associated with antibody mediated rejection in donor HLA antibody negative patients. Transplantation 2010; 90: 1473-1477.