메뉴 건너뛰기




Volumn 20, Issue 11, 2014, Pages 2157-2178

Drug therapies for ulcerative proctitis: Systematic review and meta-analysis

Author keywords

Therapy; Ulcerative colitis; Ulcerative proctitis

Indexed keywords

BETAMETHASONE; BUDESONIDE; ENEMA; HYDROCORTISONE; MESALAZINE; OLSALAZINE; PLACEBO; PREDNISOLONE; SALAZOSULFAPYRIDINE; SUCRALFATE; SULFAPYRIDINE; ANTIINFLAMMATORY AGENT;

EID: 84925621650     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0000000000000141     Document Type: Review
Times cited : (24)

References (56)
  • 1
    • 0030451868 scopus 로고    scopus 로고
    • Incidence of inflammatory bowel disease across Europe: Is there a difference between north and south? Results of the European collaborative study on inflammatory bowel disease (EC-IBD)
    • Shivananda S, Lennard-Jones J, Logan R, et al. Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European collaborative study on inflammatory bowel disease (EC-IBD). Gut. 1996;39:690-697.
    • (1996) Gut. , vol.39 , pp. 690-697
    • Shivananda, S.1    Lennard-Jones, J.2    Logan, R.3
  • 2
    • 34247586997 scopus 로고    scopus 로고
    • Changes in clinical characteristics, course, and prognosis of inflammatory bowel disease during the last 5 decades: A population-based study from Copenhagen, Denmark
    • Jess T, Riis L, Vind I, et al. Changes in clinical characteristics, course, and prognosis of inflammatory bowel disease during the last 5 decades: a population-based study from Copenhagen, Denmark. Inflamm Bowel Dis. 2007;13:481-489.
    • (2007) Inflamm Bowel Dis. , vol.13 , pp. 481-489
    • Jess, T.1    Riis, L.2    Vind, I.3
  • 3
    • 0030011214 scopus 로고    scopus 로고
    • Progression of ulcerative proctosigmoiditis: Incidence and factors influencing progression
    • Ayres RC, Gillen CD, Walmsley RS, et al. Progression of ulcerative proctosigmoiditis: incidence and factors influencing progression. Eur J Gastroenterol Hepatol. 1996;8:555-558.
    • (1996) Eur J Gastroenterol Hepatol. , vol.8 , pp. 555-558
    • Ayres, R.C.1    Gillen, C.D.2    Walmsley, R.S.3
  • 4
    • 0033952947 scopus 로고    scopus 로고
    • The natural history of ulcerative proctitis: A multicenter, retrospective study. Gruppo di Studio per le Malattie Infiammatorie Intestinali (GSMII)
    • Meucci G, Vecchi M, Astegiano M, et al. The natural history of ulcerative proctitis: a multicenter, retrospective study. Gruppo di Studio per le Malattie Infiammatorie Intestinali (GSMII). Am J Gastroenterol. 2000;95: 469-473.
    • (2000) Am J Gastroenterol. , vol.95 , pp. 469-473
    • Meucci, G.1    Vecchi, M.2    Astegiano, M.3
  • 5
    • 0032975986 scopus 로고    scopus 로고
    • Change in extent of colonoscopic and histological involvement in ulcerative colitis over time
    • Moum B, Ekbom A, Vatn MH, et al. Change in extent of colonoscopic and histological involvement in ulcerative colitis over time. Am J Gastroenterol. 1999;94:1564-1569.
    • (1999) Am J Gastroenterol. , vol.94 , pp. 1564-1569
    • Moum, B.1    Ekbom, A.2    Vatn, M.H.3
  • 7
    • 33745521197 scopus 로고    scopus 로고
    • Ulcerative colitis and clinical course: Results of a 5-year population-based follow-up study (the IBSEN study)
    • Henriksen M, Jahnsen J, Lygren I, et al. Ulcerative colitis and clinical course: results of a 5-year population-based follow-up study (the IBSEN study). Inflamm Bowel Dis. 2006;12:543-550.
    • (2006) Inflamm Bowel Dis. , vol.12 , pp. 543-550
    • Henriksen, M.1    Jahnsen, J.2    Lygren, I.3
  • 8
    • 9144235608 scopus 로고    scopus 로고
    • Oral mesalazine (5-ASA) treatment may protect against proximal extension of mucosal inflammation in ulcerative proctitis
    • Pica R, Paoluzi OA, Iacopini F, et al. Oral mesalazine (5-ASA) treatment may protect against proximal extension of mucosal inflammation in ulcerative proctitis. Inflamm Bowel Dis. 2004;10:731-736.
    • (2004) Inflamm Bowel Dis. , vol.10 , pp. 731-736
    • Pica, R.1    Paoluzi, O.A.2    Iacopini, F.3
  • 9
    • 58149401224 scopus 로고    scopus 로고
    • Mesalamine foam enema versus mesalamine liquid enema in active left-sided ulcerative colitis
    • Cortot A, Maetz D, Degoutte E, et al. Mesalamine foam enema versus mesalamine liquid enema in active left-sided ulcerative colitis. Am J Gastroenterol. 2008;103:3106-3114.
    • (2008) Am J Gastroenterol. , vol.103 , pp. 3106-3114
    • Cortot, A.1    Maetz, D.2    Degoutte, E.3
  • 10
    • 0342794493 scopus 로고
    • A double blind controlled trial of prednisolone-21-phosphate suppositories in the treatment of idiopathic proctitis
    • Lennard-Jones JE, Baron JH, Connell AM, et al. A double blind controlled trial of prednisolone-21-phosphate suppositories in the treatment of idiopathic proctitis. Gut. 1962;3:207-210.
    • (1962) Gut. , vol.3 , pp. 207-210
    • Lennard-Jones, J.E.1    Baron, J.H.2    Connell, A.M.3
  • 11
    • 7344238541 scopus 로고    scopus 로고
    • Olsalazine versus mesalazine in the treatment of mild to moderate ulcerative colitis
    • Kruis W, Brandes JW, Schreiber S, et al. Olsalazine versus mesalazine in the treatment of mild to moderate ulcerative colitis. Aliment Pharmacol Ther. 1998;12:707-715.
    • (1998) Aliment Pharmacol Ther. , vol.12 , pp. 707-715
    • Kruis, W.1    Brandes, J.W.2    Schreiber, S.3
  • 12
    • 18944363679 scopus 로고    scopus 로고
    • A new oral delivery system for 5-ASA: Preliminary clinical findings for MMx
    • Prantera C, Viscido A, Biancone L, et al. A new oral delivery system for 5-ASA: preliminary clinical findings for MMx. Inflamm Bowel Dis. 2005; 11:421-427.
    • (2005) Inflamm Bowel Dis. , vol.11 , pp. 421-427
    • Prantera, C.1    Viscido, A.2    Biancone, L.3
  • 13
    • 0023614327 scopus 로고
    • 5-aminosalicylic acid enemas in the maintenance of remission in distal ulcerative colitis and proctitis
    • Sutherland LR, Martin F. 5-aminosalicylic acid enemas in the maintenance of remission in distal ulcerative colitis and proctitis. Can J Gastroenterol. 1987;1:3-6.
    • (1987) Can J Gastroenterol. , vol.1 , pp. 3-6
    • Sutherland, L.R.1    Martin, F.2
  • 14
    • 0035990177 scopus 로고    scopus 로고
    • Effect of budesonide enema on remission and relapse rate in distal ulcerative colitis and procitis
    • Lindgren S, Löfberg R, Bergholm L, et al. Effect of budesonide enema on remission and relapse rate in distal ulcerative colitis and procitis. Scand J Gastroenterol. 2002;37:705-710.
    • (2002) Scand J Gastroenterol. , vol.37 , pp. 705-710
    • Lindgren, S.1    Löfberg, R.2    Bergholm, L.3
  • 15
    • 0029044783 scopus 로고
    • Rectal aminosalicylate therapy for distal ulcerative colitis: A meta-analysis
    • Marshall JK, Irvine EJ. Rectal aminosalicylate therapy for distal ulcerative colitis: a meta-analysis. Aliment Pharmacol Ther. 1995;9:293-300.
    • (1995) Aliment Pharmacol Ther. , vol.9 , pp. 293-300
    • Marshall, J.K.1    Irvine, E.J.2
  • 16
    • 4243762722 scopus 로고
    • Sulfasalazine inhibits cytokine production in human mononuclear cells: A novel anti-inflammatory mechanism
    • Cominelli F, Zipser RD, Dinarello CA. Sulfasalazine inhibits cytokine production in human mononuclear cells: a novel anti-inflammatory mechanism. Gastroenterology. 1992;96:A96.
    • (1992) Gastroenterology. , vol.96 , pp. A96
    • Cominelli, F.1    Zipser, R.D.2    Dinarello, C.A.3
  • 17
    • 0027451775 scopus 로고
    • Effects of zileuton, a new 5-lipoxygenase inhibitor, in experimentally induced colitis in rats
    • Zingarelli B, Squadrito F, Graziani P, et al. Effects of zileuton, a new 5-lipoxygenase inhibitor, in experimentally induced colitis in rats. Agents Actions. 1993;39:150.
    • (1993) Agents Actions. , vol.39 , pp. 150
    • Zingarelli, B.1    Squadrito, F.2    Graziani, P.3
  • 18
    • 0023221033 scopus 로고
    • Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity
    • Craven PA, Pfanstiel J, Saito R, et al. Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity. Gastroenterology. 1987;92:1998.
    • (1987) Gastroenterology. , vol.92 , pp. 1998
    • Craven, P.A.1    Pfanstiel, J.2    Saito, R.3
  • 19
    • 0017275912 scopus 로고
    • Glucocorticosteroid therapy: Mechanisms of action and clinical considerations
    • Fauci AS, Dale DC, Balow JE. Glucocorticosteroid therapy: mechanisms of action and clinical considerations. Ann Intern Med. 1976;84:304.
    • (1976) Ann Intern Med. , vol.84 , pp. 304
    • Fauci, A.S.1    Dale, D.C.2    Balow, J.E.3
  • 20
    • 0020682927 scopus 로고
    • Prednisone-induced alterations of circulating human lymphocyte subsets
    • Slade JD, Hepburn B. Prednisone-induced alterations of circulating human lymphocyte subsets. J Lab Clin Med. 1983;101:479.
    • (1983) J Lab Clin Med. , vol.101 , pp. 479
    • Slade, J.D.1    Hepburn, B.2
  • 21
    • 0023098282 scopus 로고
    • Corticosteroid-interleukin 2 interactions: Inhibition of binding of interleukin 2 to interleukin 2 receptors
    • Horst HJ, Flad HD. Corticosteroid-interleukin 2 interactions: inhibition of binding of interleukin 2 to interleukin 2 receptors. Clin Exp Immunol. 1987;68:156.
    • (1987) Clin Exp Immunol. , vol.68 , pp. 156
    • Horst, H.J.1    Flad, H.D.2
  • 22
    • 0028879819 scopus 로고
    • Role of transcriptional activation of i kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, et al. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science. 1995;270:283.
    • (1995) Science. , vol.270 , pp. 283
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3
  • 23
    • 0026758498 scopus 로고
    • The clinical pharmacology of 6-mercaptopurine
    • Lennard L. The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol. 1992;43:329.
    • (1992) Eur J Clin Pharmacol. , vol.43 , pp. 329
    • Lennard, L.1
  • 24
    • 0242464926 scopus 로고    scopus 로고
    • CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes
    • Tiede I, Fritz G, Strand S, et al. CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. J Clin Invest. 2003;111:1133.
    • (2003) J Clin Invest. , vol.111 , pp. 1133
    • Tiede, I.1    Fritz, G.2    Strand, S.3
  • 25
    • 0026077170 scopus 로고
    • The molecular action of tumor necrosis factor-alpha
    • Camussi G, Albano E, Tetta C, et al. The molecular action of tumor necrosis factor-alpha. Eur J Biochem. 1991;202:3-14.
    • (1991) Eur J Biochem. , vol.202 , pp. 3-14
    • Camussi, G.1    Albano, E.2    Tetta, C.3
  • 26
    • 84873137028 scopus 로고    scopus 로고
    • Oral 5-aminosailcylic acid for induction of remission in ulcerative colitis
    • Feagan BG, MacDonald JK. Oral 5-aminosailcylic acid for induction of remission in ulcerative colitis. Cochrane Database of Syst Rev. 2012;10: CD000544.
    • (2012) Cochrane Database of Syst Rev. , vol.10 , pp. CD000544
    • Feagan, B.G.1    Macdonald, J.K.2
  • 27
    • 77950889396 scopus 로고    scopus 로고
    • Rectal 5-aminosalicylic acid for induction of remission in ulcerative colitis
    • Marshall JK, Thabane M, Steinhart AH, et al. Rectal 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database of Syst Rev. 2010;1:CD004115.
    • (2010) Cochrane Database of Syst Rev. , vol.1 , pp. CD004115
    • Marshall, J.K.1    Thabane, M.2    Steinhart, A.H.3
  • 28
    • 84873153604 scopus 로고    scopus 로고
    • Rectal 5-aminosalicylic acid for maintenance of remission in ulcerative colitis
    • Marshall JK, Thabane M, Steinhart AH, et al. Rectal 5-aminosalicylic acid for maintenance of remission in ulcerative colitis. Cochrane Database of Syst Rev. 2012;11:CD004118.
    • (2012) Cochrane Database of Syst Rev. , vol.11 , pp. CD004118
    • Marshall, J.K.1    Thabane, M.2    Steinhart, A.H.3
  • 29
    • 79953777773 scopus 로고    scopus 로고
    • Glucocorticosteroid therapy in inflammatory bowel disease: Systematic review and meta-analysis
    • Ford AC, Bernstein CN, Khan JK, et al. Glucocorticosteroid therapy in inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol. 2011;106:590-599.
    • (2011) Am J Gastroenterol. , vol.106 , pp. 590-599
    • Ford, A.C.1    Bernstein, C.N.2    Khan, J.K.3
  • 30
    • 84873020600 scopus 로고    scopus 로고
    • Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis
    • Timmer A, McDonald JWD, Tsoulis DJ, et al. Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis. Cochrane Database of Syst Rev. 2012;9:CD000478.
    • (2012) Cochrane Database of Syst Rev. , vol.9 , pp. CD000478
    • Timmer, A.1    McDonald, J.W.D.2    Tsoulis, D.J.3
  • 31
    • 84903362250 scopus 로고    scopus 로고
    • Systematic review with network meta-analysis: The efficacy of anti-tumour necrosis factor-alpha agents for the treatment of ulcerative colitis
    • Stidham RW, Lee TC, Higgins PD, et al. Systematic review with network meta-analysis: the efficacy of anti-tumour necrosis factor-alpha agents for the treatment of ulcerative colitis. Aliment Pharmacol Ther. 2014;39:660-671.
    • (2014) Aliment Pharmacol Ther. , vol.39 , pp. 660-671
    • Stidham, R.W.1    Lee, T.C.2    Higgins, P.D.3
  • 33
    • 0021909115 scopus 로고
    • Beta blockade during and after myocardial infarction: An overview of the randomized trials
    • Yusuf S, Peto R, Lewis J, et al. Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis. 1985;27:335-371.
    • (1985) Prog Cardiovasc Dis. , vol.27 , pp. 335-371
    • Yusuf, S.1    Peto, R.2    Lewis, J.3
  • 34
    • 78249266327 scopus 로고    scopus 로고
    • Clinical trial: A novel high-dose 1 g mesalamine suppository (Salofalk) once daily is as efficacious as a 500-mg suppository thrice daily in active ulcerative proctitis
    • Andus T, Kocjan A, Müser M, et al. Clinical trial: a novel high-dose 1 g mesalamine suppository (Salofalk) once daily is as efficacious as a 500-mg suppository thrice daily in active ulcerative proctitis. Inflamm Bowel Dis. 2010;16:1747-1756.
    • (2010) Inflamm Bowel Dis. , vol.16 , pp. 1747-1756
    • Andus, T.1    Kocjan, A.2    Müser, M.3
  • 35
    • 0029843249 scopus 로고    scopus 로고
    • Sucralfate and hydrocortisone enemas in the treatment of active ulcerative proctitis-A randomized singleblind comparative study
    • Ardizzone S, Petrillo M, Antonacci CM, et al. Sucralfate and hydrocortisone enemas in the treatment of active ulcerative proctitis-a randomized singleblind comparative study. Aliment Pharmacol Ther. 1996;10:957-960.
    • (1996) Aliment Pharmacol Ther. , vol.10 , pp. 957-960
    • Ardizzone, S.1    Petrillo, M.2    Antonacci, C.M.3
  • 36
    • 0015218286 scopus 로고
    • Betamethasone 17-valerate, prednisolone 21-phosphate retention enemata in proctocolitis
    • Betamethasone 17-valerate, prednisolone 21-phosphate retention enemata in proctocolitis. Br Med J. 1971;3:84-86.
    • (1971) Br Med J , vol.3 , pp. 84-86
  • 37
    • 0023819344 scopus 로고
    • 5-Aminosalicylic acid as enemas or suppositories in distal ulcerative colitis?
    • Campieri M, Gionchetti P, Belluzzi A, et al. 5-Aminosalicylic acid as enemas or suppositories in distal ulcerative colitis? J Clin Gastroenterol. 1988;10:406-409.
    • (1988) J Clin Gastroenterol. , vol.10 , pp. 406-409
    • Campieri, M.1    Gionchetti, P.2    Belluzzi, A.3
  • 38
    • 0025322421 scopus 로고
    • Mesalazine (5-aminosalicylic acid) suppositories in the treatment of ulcerative proctitis or distal proctosigmoiditis. A randomized controlled trial
    • Campieri M, De Franchis R, Bianchi Porro G, et al. Mesalazine (5-aminosalicylic acid) suppositories in the treatment of ulcerative proctitis or distal proctosigmoiditis. A randomized controlled trial. Scand J Gastroenterol. 1990;25:663-668.
    • (1990) Scand J Gastroenterol. , vol.25 , pp. 663-668
    • Campieri, M.1    De Franchis, R.2    Bianchi Porro, G.3
  • 39
    • 0025376146 scopus 로고
    • Topical treatment with 5-aminosalicylic in distal ulcerative colitis by using a new suppository preparation. A double-blind placebo controlled trial
    • Campieri M, Gionchetti P, Belluzzi A, et al. Topical treatment with 5-aminosalicylic in distal ulcerative colitis by using a new suppository preparation. A double-blind placebo controlled trial. Int J Colorectal Dis. 1990;5:79-81.
    • (1990) Int J Colorectal Dis. , vol.5 , pp. 79-81
    • Campieri, M.1    Gionchetti, P.2    Belluzzi, A.3
  • 40
    • 35449008088 scopus 로고    scopus 로고
    • Clinical trial: Randomizedcontrolled clinical study comparing the efficacy and safety of a lowvolume vs. A high-volume mesalazine foam in active distal ulcerative colitis
    • Eliakim R, Tulassay Z, Kupcinskas L, et al. Clinical trial: randomizedcontrolled clinical study comparing the efficacy and safety of a lowvolume vs. a high-volume mesalazine foam in active distal ulcerative colitis. Aliment Pharmacol Ther. 2007;26:1237-1249.
    • (2007) Aliment Pharmacol Ther. , vol.26 , pp. 1237-1249
    • Eliakim, R.1    Tulassay, Z.2    Kupcinskas, L.3
  • 41
    • 0028830213 scopus 로고
    • Mesalazine suppositories versus hydrocortisone foam in patients with distal ulcerative colitis
    • Farup PG, Hovde O, Halvorsen FA, et al. Mesalazine suppositories versus hydrocortisone foam in patients with distal ulcerative colitis. Scand J Gastroenterol. 1995;30:164-170.
    • (1995) Scand J Gastroenterol. , vol.30 , pp. 164-170
    • Farup, P.G.1    Hovde, O.2    Halvorsen, F.A.3
  • 42
    • 0030862269 scopus 로고    scopus 로고
    • Comparison of mesalazine suppositories in proctitis and distal proctosigmoiditis
    • Gionchetti P, Rizzello F, Venturi A, et al. Comparison of mesalazine suppositories in proctitis and distal proctosigmoiditis. Aliment Pharmacol Ther. 1997;11:1053-1057.
    • (1997) Aliment Pharmacol Ther. , vol.11 , pp. 1053-1057
    • Gionchetti, P.1    Rizzello, F.2    Venturi, A.3
  • 43
    • 0031963091 scopus 로고    scopus 로고
    • Comparison of oral with rectal mesalazine in the treatment of ulcerative proctitis
    • Gionchetti P, Rizzello F, Venturi A, et al. Comparison of oral with rectal mesalazine in the treatment of ulcerative proctitis. Dis Colon Rectum. 1998;41:93-97.
    • (1998) Dis Colon Rectum. , vol.41 , pp. 93-97
    • Gionchetti, P.1    Rizzello, F.2    Venturi, A.3
  • 44
    • 33644907461 scopus 로고    scopus 로고
    • Budesonide foam versus budesonide enema in active ulcerative proctitis and proctosigmoiditis
    • Gross V, Bar-Meir S, Lavy A, et al. Budesonide foam versus budesonide enema in active ulcerative proctitis and proctosigmoiditis. Aliment Pharmacol Ther. 2006;23:303-312.
    • (2006) Aliment Pharmacol Ther. , vol.23 , pp. 303-312
    • Gross, V.1    Bar-Meir, S.2    Lavy, A.3
  • 45
    • 33644653559 scopus 로고    scopus 로고
    • Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis; The ASCEND II trial
    • Hanauer SB, Sandborn WJ, Kornbluth A, et al. Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis; the ASCEND II trial. Am J Gastroenterol. 2005; 100:2478-2485.
    • (2005) Am J Gastroenterol. , vol.100 , pp. 2478-2485
    • Hanauer, S.B.1    Sandborn, W.J.2    Kornbluth, A.3
  • 46
    • 21844438005 scopus 로고    scopus 로고
    • Efficacy and safety of mesalamine 1 g HS versus 500mg BID suppositories in mild to moderate ulcerative proctitis: A multicenter randomized study
    • Larnet M, Ptak T, Dallaire C, et al. Efficacy and safety of mesalamine 1 g HS versus 500mg BID suppositories in mild to moderate ulcerative proctitis: a multicenter randomized study. Inflamm Bowel Dis. 2005;11: 625-630.
    • (2005) Inflamm Bowel Dis. , vol.11 , pp. 625-630
    • Larnet, M.1    Ptak, T.2    Dallaire, C.3
  • 47
    • 0033802393 scopus 로고    scopus 로고
    • Efficacy and tolerability of mesalazine foam enema (Salofalk foam) for distal ulcerative colitis: A double-blind, randomized, placebo-controlled study
    • Pokrotnieks J, Marlicz K, Paradowski L, et al. Efficacy and tolerability of mesalazine foam enema (Salofalk foam) for distal ulcerative colitis: a double-blind, randomized, placebo-controlled study. Aliment Pharmacol Ther. 2000;14:1191-1198.
    • (2000) Aliment Pharmacol Ther. , vol.14 , pp. 1191-1198
    • Pokrotnieks, J.1    Marlicz, K.2    Paradowski, L.3
  • 48
    • 0018961746 scopus 로고
    • Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: A study t determine the active therapeutic moiety of sulphasalazine
    • van Hees PAM, Bakker JH, van Tongeren JHM. Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study t determine the active therapeutic moiety of sulphasalazine. Gut. 1980;21:632-635.
    • (1980) Gut. , vol.21 , pp. 632-635
    • Van Hees, P.A.M.1    Bakker, J.H.2    Van Tongeren, J.H.M.3
  • 49
    • 0023960187 scopus 로고
    • Double-blind comparison of 5-aminosalicylic acid and acetyl-5-aminosalicylic acid suppositories in patients with idiopathic proctitis
    • van Hogezand RA, van Hees PAM, van Gorp JPWM, et al. Double-blind comparison of 5-aminosalicylic acid and acetyl-5-aminosalicylic acid suppositories in patients with idiopathic proctitis. Aliment Pharmacol Ther. 1988;2:33-40.
    • (1988) Aliment Pharmacol Ther. , vol.2 , pp. 33-40
    • Van Hogezand, R.A.1    Van Hees, P.A.M.2    Van Gorp, J.P.W.M.3
  • 50
    • 84879786241 scopus 로고    scopus 로고
    • Randomised clinical trial: Evaluation of the efficacy of mesalazine (mesalamine) suppositories in patients with ulcerative colitis and active rectal inflammation-A placebo-controlled study
    • Watanabe M, Nishino H, Sameshima Y, et al. Randomised clinical trial: evaluation of the efficacy of mesalazine (mesalamine) suppositories in patients with ulcerative colitis and active rectal inflammation- a placebo-controlled study. Aliment Pharmacol Ther. 2013;38: 264-273.
    • (2013) Aliment Pharmacol Ther. , vol.38 , pp. 264-273
    • Watanabe, M.1    Nishino, H.2    Sameshima, Y.3
  • 51
    • 0023611015 scopus 로고
    • Double-blind, placebo-controlled evaluation of 5-asa suppositories in active distal proctitis and measurement of extent of sread using 99mTc-labeled 5-asa suppositories
    • Williams CN, Haber G, Aquino JA. Double-blind, placebo-controlled evaluation of 5-asa suppositories in active distal proctitis and measurement of extent of sread using 99mTc-labeled 5-asa suppositories. Dig Dis Sci. 1987;32:71S-75S.
    • (1987) Dig Dis Sci. , vol.32 , pp. 71S-75S
    • Williams, C.N.1    Haber, G.2    Aquino, J.A.3
  • 52
    • 0032081148 scopus 로고    scopus 로고
    • Maintenance treatment of ulcerative proctitis with mesalazine suppositories: A double blind placebo-controlled trial
    • d'Albasio G, Paoluzi P, Campieri M, et al. Maintenance treatment of ulcerative proctitis with mesalazine suppositories: a double blind placebo-controlled trial. Am J Gastroenterol. 1998;93:799-803.
    • (1998) Am J Gastroenterol. , vol.93 , pp. 799-803
    • D'albasio, G.1    Paoluzi, P.2    Campieri, M.3
  • 53
    • 0025049819 scopus 로고
    • 5-aminosalicylic acid suppositories in the maintenance of remission in idiopathic proctitis or proctosigmoidits: A double-blind placebo-controlled clinical trial
    • d'Arienzo A, Panarese A, d'Armiento FP, et al. 5-aminosalicylic acid suppositories in the maintenance of remission in idiopathic proctitis or proctosigmoidits: a double-blind placebo-controlled clinical trial. Am J Gastroenterol. 1990;85:1079-1082.
    • (1990) Am J Gastroenterol. , vol.85 , pp. 1079-1082
    • D'arienzo, A.1    Panarese, A.2    D'armiento, F.P.3
  • 54
    • 0033944175 scopus 로고    scopus 로고
    • Long-term use of mesalamine (Rowasa suppositories in remission maintenance in ulcerative proctitis)
    • Hanauer SB, Good LI, Goodman MW, et al. Long-term use of mesalamine (Rowasa suppositories in remission maintenance in ulcerative proctitis). Am J Gastroenterol. 2000;95:1749-1754.
    • (2000) Am J Gastroenterol. , vol.95 , pp. 1749-1754
    • Hanauer, S.B.1    Good, L.I.2    Goodman, M.W.3
  • 55
    • 0028919406 scopus 로고
    • Olsalazine versus sulphasalazine for relapse prevention in ulcerative colitis: A multicenter study
    • Nilsson A, Danielsson A, Löfberg R, et al. Olsalazine versus sulphasalazine for relapse prevention in ulcerative colitis: a multicenter study. Am J Gastroenterol. 1995;90:381-387.
    • (1995) Am J Gastroenterol. , vol.90 , pp. 381-387
    • Nilsson, A.1    Danielsson, A.2    Löfberg, R.3
  • 56
    • 0028071107 scopus 로고
    • Optimum dose of olsalazine for maintaining remission in ulcerative colitis
    • Travis SPL, Tysk C, de Silva HJ, et al. Optimum dose of olsalazine for maintaining remission in ulcerative colitis. Gut. 1994;35:1282-1286.
    • (1994) Gut. , vol.35 , pp. 1282-1286
    • Travis, S.P.L.1    Tysk, C.2    De Silva, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.